• Title/Summary/Keyword: growth point

Search Result 1,901, Processing Time 0.029 seconds

THE EXISTENCE OF THE SOLUTION OF ELLIPTIC SYSTEM APPLYING TWO CRITICAL POINT THEOREM

  • Nam, Hyewon
    • Journal of the Chungcheong Mathematical Society
    • /
    • v.31 no.1
    • /
    • pp.53-64
    • /
    • 2018
  • This paper deals with the study of solutions for the elliptic system with jumping nonlineartity and growth nonlinearity and Dirichlet boundary condition. We apply the two critical point theorem when proving the existence of nontrivial solutions for the elliptic system. We define the energy functional associated to the elliptic system and prove that the functional has two critical values.

A Cephalometric Study of Lateral Morphologic Features in Adult Cleft Lip and Palate Patients (구순 구개열 환자의 성장후 측모형태에 관한 두부계측방사선학적 연구)

  • Chang, Ic-Jun;Sohn, Woo-Ill;Song, Jae-Chul;Chin, Byung-Rho
    • Journal of Yeungnam Medical Science
    • /
    • v.18 no.1
    • /
    • pp.112-122
    • /
    • 2001
  • Background: Cleft lip and palate deformity have unknown patterns of maxillofacial growth and development. The maxillofacial growth can be affected either by congenital or environmental factors such as infection and trauma. Surgical repair of cleft lip and palate may interfere the subsequent growth and development of maxillofacial region. The purpose of this study is to evaluate the characteristics of maxillofacial growth patterns in adult cleft lip and palate patients. Materials and Methods: The material for this study consisted of 17 adult male patients with cleft lip and palate. Cephalometric tracing and measurements were done by one investigator. The relationship between 17 cleft lip and palate patients and Korean norms were evaluated statistically. Results: There were statistically differences in Na. perpendicular to point A, SNA angle, effective maxillary length, maxillofacial differencial. Wit's appraisal and upper incisor to point A(p < 0.01). Pogonion to Na. perpendicular also statistically differed(p < 0.05). Other measurements didn't statistically differ. Conclusion: It was evident that in adult cleft lip and palate patients, maxilla was retruded and short. Careful cleft lip and palate repair and treatment are recommended for facilitating normal growth of maxilla.

  • PDF

Effect of Incorrectly Estimated Parameters on the Control of Specific Growth Rate in E. coli Fed-Batch Fermentation

  • Park, Tai-Hyun;Yoon, Sung-Kwan;Kang, Whan-Koo
    • Biotechnology and Bioprocess Engineering:BBE
    • /
    • v.1 no.1
    • /
    • pp.22-25
    • /
    • 1996
  • An Exponetial feeding strategy has been frequently used in fed-batch fermentation of recombinant E. coli. In this feeding scheme, growth yield and initial cell concentration, which can be erroneously determined, are needed to calculate the feed rate for controlling specific growth rate at the set point. The effect of the incorrect growth yield and initial cell concentration on the control of the specific growth rate was theoretically analyzed. Insignificance of the correctness of those parameters for the control of the specific growth rate was shown theoretically and experimentally.

  • PDF

The influence of atomosphere on high temperature crystal growth

  • Klimm, D.;Schroder, W.
    • Journal of the Korean Crystal Growth and Crystal Technology
    • /
    • v.9 no.4
    • /
    • pp.360-364
    • /
    • 1999
  • The growth of crystals with high melting point$t_{fus}$$\geq$$1600^{\circ}C$ faces the researcher with experimental problems, as the choice of materials that withstand such high t is rather limited. Many metallic construction materials are in this high t range already molten or exhibit at least a drastically reduced mechanical strength. The very few materials with$t_{fus}$$1600^{\circ}C$ as e.g. W, Mo, and partially even Ir are more or less sensitive against oxygen upon heating. Whenever possible, high t crystal growth is performed under inert atmosphere (noble gases). Unfortunately, many oxides are not thermodynamically stable under such conditions, as reduction takes place within such atmosphere. A thoroughly search for suitable growth conditions has to be performed, that are on the one side "oxidative enough" to keep the oxides stable and on the other side "reductive enough" to avoid destruction of constructive parts of the crystal growth assembly. The relevant parameters are t and the oxygen partial pressure${po}_{2}$. The paper discusses quantitatively relevant properties of interesting oxides and construction materials and wasy to forecast theri behavior under growth conditions.

  • PDF

Relationship between Pattern of Fatigue Crack Surface and Fatigue Crack Growth Behavior under $K_{III}$ Mode-Four Point Shear in Al 5083-O

  • Kim Gun-Ho;Won Young-Jun;Sakakur Keigo;Fujimot Takehiro;Nishioka Toshihisa
    • Journal of Advanced Marine Engineering and Technology
    • /
    • v.30 no.4
    • /
    • pp.474-482
    • /
    • 2006
  • Generally almost all fatigue crack growth is affected by mode I. For this reason a study on mode I has concentrated in the field of fracture mechanics. However the fatigue crack initiation and growth in machines and structures usually occur in mixed mode loading. If there is any relationship between the cause of fracture in mixed mode loading and fracture surface, fracture surface pattern will be the main mean explaining reasons of fatigue fracture and obtaining further information about fracture process. In this paper low point shear-fatigue test with Aluminum alloy hi 5083-O is carried out from this prospect and then the mixed mode distribution of fracture surface is examined from the result after identifying the generation of fatigue crack surface pattern. It was found from the experimental results that the fatigue crack surface pattern and the fatigue crack shear direction are remarkably consistent. Furthermore It is possible that the analysis of distribution of mixed mode through the fatigue crack surface pattern.

Relationship between Pattern of Fatigue Crack Surface and Fatigue Crack Growth Behavior under $K_{III}$ Mode-Four Point Shear in Al 5083-O (Al 5083-O재에 있어서 $K_{III}$ 모드 4점 전단 하에서의 피로파단면 무늬와 피로균열진전거동의 관계)

  • Kim, Gun-Ho;Won, Young-Jun;Sakakura, Keigo;Fujimoto, Takehiro;Nishioka, Toshihisa
    • Proceedings of the Korean Society of Marine Engineers Conference
    • /
    • 2006.06a
    • /
    • pp.43-44
    • /
    • 2006
  • Generally almost all fatigue crack growth is affected by model. For this reason a study on model has concentrated in the field of fracture mechanics. However the fatigue crack initiation and growth in machines and structures usually occur in mixed mode loading. If there is any relationship between the cause of fracture in mixed mode loading and fracture surface, fracture surface pattern will be the main mean explaining reasons of fatigue fracture and obtaining further information about fracture process. In this paper four point shear-fatigue test with Aluminum alloy Al 5083-O is carried out from this prospect and then the mixed mode distribution of fracture surface is examined from the result after identifying the generation of fatigue crack surface pattern. It was found from the experimental results that the fatigue crack surface pattern and the fatigue crack shear direction are remarkably consistent. Furthermore It is possible that the analysis of distribution of mixed mode through the fatigue crack surface pattern.

  • PDF

Silymarin-Mediated Degradation of c-Myc Contributes to the Inhibition of Cell Proliferation in Human Colorectal Cancer Cells

  • Eo, Hyun Ji;Jeong, Jin Boo;Koo, Jin Suk;Jeong, Hyung Jin
    • Korean Journal of Plant Resources
    • /
    • v.30 no.3
    • /
    • pp.265-271
    • /
    • 2017
  • In this study, we elucidated the molecular mechanism of silymarin by which silymarin may inhibits cell proliferation in human colorectal cancer cells in order to search the new potential anti-cancer target associated with the cell growth arrest. Silymarin reduced the level of c-Myc protein but not mRNA level indicating that silymarin-mediated downregulation of c-Myc may result from the proteasomal degradation. In the confirmation of silymarin-mediated c-Myc degradation, MG132 as a proteasome inhibitor attenuated c-Myc degradation by silymarin. In addition, silymarin phosphorylated the threonine-58 (Thr58) of c-Myc and the point mutation of Thr58 to alanine blocked its degradation by silymarin, which indicates that Thr58 phosphorylation may be an important modification for silymarin-mediated c-Myc degradation. We observed that the inhibition of ERK1/2, p38 and $GSK3{\beta}$ blocked the Thr58 phosphorylation and subsequent c-Myc degradation by silymarin. Finally, the point mutation of Thr58 to alanine attenuated silymarin-mediated inhibition of the cell growth. The results suggest that silymarin induces the cell growth arrest through c-Myc proteasomal degradation via ERK1/2, p38 and $GSK3{\beta}-dependent$ Thr58 phosphorylation.

A Parameter Estimation of Software Reliability Growth Model with Change-Point (변화점을 고려한 소프트웨어 신뢰도 성장모형의 모수추정)

  • Kim, Do-Hoon;Park, Chun-Gun;Nam, Kyung-H.
    • The Korean Journal of Applied Statistics
    • /
    • v.21 no.5
    • /
    • pp.813-823
    • /
    • 2008
  • The non-homogeneous Poisson process(NHPP) based software reliability growth models are proved quite successful in practical software reliability engineering. The fault detection rate is usually assumed to be the continuous and monotonic function. However, the fault detection rate can be affected by many factors such as the testing strategy, running environment and resource allocation. This paper describes a parameter estimation of software reliability growth model with change-point problem. We obtain the maximum likelihood estimate(MLE) and least square estimate(LSE), and compare goodness-of-fit.

Metalorganic Chemical Vapor Deposition of Aluminum Thin Film for ULSI Using Dimethylethylamine Alane(DMEAA) (DMEAA를 이용한 초고집적 회로용 알루미늄 박막의 제조)

  • 이기호;김병엽;이시우
    • Journal of the Korean Vacuum Society
    • /
    • v.4 no.S1
    • /
    • pp.81-86
    • /
    • 1995
  • Aluminum has been deposited selectively on TiN surfaces in the presence of Si, SiO2 from Dimethyethylamine Alane(DMEAA). The film properties of the deopsited AI film were determined by various methods(SEM, Auger, UV-photospectrometer, Four point-probe, XRD). The effect of in-situ H2 plasma precleaning was studied. The effect of gap distance, pressure and temperature on the properties(crystallinity, resistance, grain size, morphology) of AI film and on the growth rates was investigated. It was found that the plasma precleaning promotes the growth rate and there exists optimum thmperature for maximum growth rate.

  • PDF