• 대한소아치과학회지
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• 제44권1호
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• pp.108-115
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• 2017

매복치의 치료방법으로 교정적 견인, 발치 후 임플란트, 자가치아이식 등 다양한 치료 방법이 있다. 그 중에서도 자가치아이식은 성장하는 환자들에게서 이식치 고유의 치주인대세포의 보존 및 치조골 성장이 가능하다는 점에서 좋은 치료방법이라고 생각된다. 이 증례에서는 성장중인 청소년의 이소 매복 치아를 자가치아이식으로 치료한 두 개의 증례를 소개하고자 한다. 첫 번째 증례에서 이소 매복된 좌측 하악 제2소구치를 발거 후 정위치로 자가치아이식하였고 혈소판 농축 피브린(PRF)과 mineral trioxide aggregate (MTA)를 사용하여 재생 근관 치료를 하였다. 석회화 치성낭으로 인해 이소매복된 좌측 하악 제2대구치를 지닌 두 번째 증례에서 병소의 적출술을 시행하였다. Obturator를 3개월 간 장착하여 매복치아의 자발적 맹출을 기대하였으나 맹출 양상이 없어 자가치아이식한 후 MTA를 이용한 근관치료를 하였다. 두 증례 모두 자가치아이식술로 이소매복치를 간단하고 빠르게 치료하였다. 성장하는 환자에게서 이소매복치의 자가치아 이식술은 임플란트나 보철물 수복 대신 좋은 치료 방법이 될 것이다.

• 생명과학회지
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• 제19권5호
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• pp.671-675
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• 2009

Prostate cancer has been a critical health problem due to an increase of prostate cancer-related deaths worldwide. Also, a frequent treatment option for prostate cancer is androgen ablation, but this treatment has a limited scope, especially for hormone-refractory cancer. There is an urgent need for the identification of alternative therapeutic strategies for prostate cancer. Previously, over one hundred species of dried-plant methanol extracts were tested for inhibitory effects on proliferation. One of them, Piper longum Linn. was selected based on its potent anti-proliferation effect. The dried root of P. longum Linn. was extracted with 100% methanol for 2-3 days and its extract was fractionated using chloroform. The chloroform layer was then subjected to column chromatography on silica gel, reverse phase-18 (RP-18) and Sephadex LH-20, in turn. Finally, the pure compound was obtained and identified as pipernonaline by NMR spectroscopic and physico-chemical analysis. In this study, anti-proliferation and cell cycle arrest effects of pipernonaline on human prostate cancer PC-3 cells were investigated using the MTT and PI staining, respectively. Our findings suggest that pipernonaline represents a dose-dependent growth inhibition pattern on PC-3 cells and, moreover, its growth inhibition is associated with sub-G1 and G0/G1 cell cycle accumulation in PC-3 cells. Also, these results provide an anticancer candidate for human prostate cancer.

• 대한간호학회지
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• 제3권1호
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• pp.41-51
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• 1972

In this article, the writer attempted to study the followings: (1) mother's knowledge of milk feeding (including method of sterilization, formula and feeding) (2) reasons of artificial feeding (3) how much mothers are concerned about their artificial feeding infants (4) condition of growth and development of artificial feeding infants. As the object of study, 96 mothers with artificial feeding infants, who had consulted dep't of pediatrics of two Hospitals in Seoul (Korea Hospital and Med. College Woo Suk Hospital, Korea Uni.) and well baby clinic of the two Health Centers (Sung Dong and Dongdaemoon), were randomly sampled. The data were treated by the statistic method of chi-square and percentage, and come to the following conclusion. 1. Knowledge of milk feeding Sterilization: 70 percentages of mothers know about the milk sterilization (including bottle, nipple and instrument), but 55 percentages of them do not know the nipple sterilization correctly. Formula: 69 percentages of mothers follow the indicator or in accordance with doctor's directions, but 31 percentages do at their option by reasons that the baby often coughs up the milk, the baby is too small, the baby often has digestive troubles, or the baby grow fleshy heavily etc, except family economic problems. Feeding: only half of mothers know the correct feeding method, especially they do not know how to determine the heat degree of milk and how to bubble up the baby correctly. They just do feeding according to the accepted usages. 2. Reasons of artificial feeding Of the reasons of artificial feeding, 18 percentages were caused by infants and 82 percentages by mothers. Most of the reasons are mainly due to the lack of breast milk and sufficient supply of nourishments rather than mother's deficiency or mother's abnormality. 3. Mother's concern for artificial feeding infants Mothers who are sharply concerned for their artificial feeding baby's growth and development: 63%, mothers who made the baby (artificial feeding infant) routine vaccinated: 81%, mothers who ear anxious about the baby's future personality forming : 68%, mothers who care about the baby's condition of nourishment; 60%, mothers who are anxious about tile selection of baby's food; 54%. 4. The growth and development of artificial feeding infants compared with Korean average infants. The artificial feeding infants are above the Korean average infants in stature by 1.21 centimeters and in weight by 0.3 kilograms. Conclusion: It has been said that there is no better food for infant than the breast milk. However, the artificial feeding has been used for the supplement of nourishments and as substitute food for the breast milk. And this artificial feeding could give the married women the chance to act in society and more opportunity to develop themselves and to work for others at home and other fields. Considering these advantages, artificial feeding should not be exclusive, but preferably should be more improved and inquired positively. And even in artificial feeding, what is most important is that mothers should recognize the requirement and need of artificial feeding clearly and correctly, and they should be accustomed to the correct knowledge and skills of artificial feeding in order to practice it appropriately. In some degree, they should be properly trained in school education process.

• Journal of Korean Neurosurgical Society
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• 제59권5호
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• pp.437-441
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• 2016

Objective : Recently, regenerative therapies have been used in clinical trials (heart, cartilage, skeletal). We don't make use of these treatments to spinal cord injury (SCI) patients yet, but regenerative therapies are rising interest in recent study about SCI. Neural precursor/stem cell (NPSC) proliferation is a significant event in functional recovery of the central nervous system (CNS). However, brain NPSCs and spinal cord NPSCs (SC-NPSCs) have many differences including gene expression and proliferation. The purpose of this study was to investigate the influence of neural growth factor (NGF) on the proliferation of SC-NPSCs. Methods : NPSCs ($2{\times}10^4$) were suspended in $100{\mu}L$ of neurobasal medium containing NGF-7S (Sigma-Aldrich) and cultured in a 96-well plate for 12 days. NPSC proliferation was analyzed five times for either concentration of NGF (0.02 and 2 ng/mL). Sixteen rats after SCI were randomly allocated into two groups. In group 1 (SCI-vehicle group, n=8), animals received 1.0 mL of the saline vehicle solution. In group 2 (SCI-NGF group, n=8), the animals received single doses of NGF (Sigma-Aldrich). A dose of 0.02 ng/mL of NGF or normal saline as a vehicle control was intra-thecally injected daily at 24 hour intervals for 7 days. For Immunohistochemistry analysis, rats were sacrificed after one week and the spinal cords were obtained. Results : The elevation of cell proliferation with 0.02 ng/mL NGF was significant (p<0.05) but was not significant for 2 ng/mL NGF. The optical density was increased in the NGF 0.02 ng/mL group compared to the control group and NGF 2 ng/mL groups. The density of nestin in the SCI-NGF group was significantly increased over the SCI-vehicle group (p<0.05). High power microscopy revealed that the density of nestin in the SCI-NGF group was significantly increased over the SCI-vehicle group. Conclusion : SC-NPSC proliferation is an important pathway in the functional recovery of SCI. NGF enhances SC-NPSC proliferation in vitro and in vivo. NGF may be a useful option for treatment of SCI patients pending further studies to verify the clinical applicability.

• 한국습지학회지
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• 제16권1호
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• pp.61-72
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• 2014

높은 생산성을 위한 인공습지 조성 및 관리 방안 제시를 위해 세 가지 대형정수식물(갈대, 애기부들, 줄)을 두 가지 매질조건(개별 매질과 혼합 매질)과 두 가지 수위 조건(5 cm와 20 cm)에 식재한 뒤 3년간의 모니터링을 수행하였다. 그 결과 줄의 경우 조성 환경에 상관없이 첫 해 초기 생육(최대 초고, 약 200 cm; 최대 지상부 생산성 약 500 $g/m^2$)뿐만 아니라 3년경과 후 최종 생육(줄, 약 1,100 $g/m^2$; 애기부들, 770 $g/m^2$; 갈대, 450 $g/m^2$)에 있어, 전반적으로 갈대나 애기부들에 비해 월등하게 나타났다. 특히 초기 생육이 좋았던 줄은 자연적으로 유입돼 발생하는 잡초들에 의한 피해가 거의 없었던 반면 갈대나 애기부들의 경우 다년생 잡초를 포함한 여러 잡초와의 종간 경쟁으로 생육이 다소 부진하였다. 특히 얕은 수심환경과 moss peat를 포함한 혼합 매질 조건에선 식재종들의 생육이 전반적으로 부진하였으며, 그로 인해 잡초들의 생육이 상대적으로 좋았다. 높은 지상부 생산성을 위한 인공습지 조성을 위해선 줄과 같이 생육 환경에 크게 구애받지 않으며 초기 생육이 뛰어난 종의 선발을 통해 자연유입 잡초나 야생동물 등에 의한 피해를 최소화시켜야 할 것이다. 만약 줄이 아닌 갈대나 애기부들과 같은 종을 식재하고자 한다면 온실과 같은 환경에서 일정 수준 이상 생육시킨 뒤 식재함으로써 더욱 경쟁력을 제고시킬 수 있을 것이다. 더불어 높은 지상부 생산성을 위한 인공습지를 지속적으로 유지시키기 위해선 한두 가지 선택지가 아닌 제초와 관련된 최적의 관리방안들을 적시에 활용하는 통합적 잡초 관리 시스템의 적용을 제안하는 바이다.

• 한국자원식물학회지
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• 제36권2호
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• pp.172-180
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• 2023

후박나무 묘목의 효율적인 생산을 위해 시비농도에 따른 간장, 근원경, 묘목품질지수, 광합성 반응 측정으로 생장과 생리적 특성을 조사하고 적정 용기묘 생산에 적합한 시비량을 확인하였다. 광합성 특성은 대조구에 비해 시비처리구에서 순광합성속도(A), 순간증산효율(ITE), 내재적 수분이용효율(WUEi), 최대카르복실화속도(Vcmax) 등 높았다. 특히, 시비 농도는 활발한 가스교환을 통해 비교적 높은 A, Vcmax 보였던1000 mg/L과 기공개폐 기작의 조절로 광합성 반응기작을 향상시킨500 mg/L가 적정 수준의 시비로 실험 결과를 보였다. 생장량 또한 대조구보다 시비처리구에서 묘목의 품질지수 등 통계적으로 높은 것으로 나타났다. 특히, 1000 mg/L은 근원경, 간장이 처리구 중 가장 큰 특징을 보였으며, 잎, 줄기, 전체 건중량, 역시 다른 처리구들에 비해 통계적으로 높았고, 묘목의 품질을 나타내는 H/D율 및 T/R율도 건전한 수준인 것을 볼 수 있었다. 500 mg/L 역시 양호한 생육 특성을 보여 경제성을 고려한다면 한 가지 선택지가 될 수 있다고 여겨진다. 그러나 2000 mg/L의 경우, 근원경의 감소로 H/D율은 높아졌고, 지상부에 비해 지하부로의 물질분배가 저조하여 T/R율 역시 증가하는 형태적 특성과 비용 저감을 위한 경제성을 고려하였을 때 2000 mg/L의 시비농도는 과하다고 판단된다. 따라서 후박나무 용기묘의 시비는 500 mg/L 혹은 1000 mg/L이 경제적으로나 식물의 형태적으로 가장 이상적인 시비량이라고 판단된다.

• Asian-Australasian Journal of Animal Sciences
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• 제9권6호
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• pp.615-635
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• 1996

The animal industry must be environmentally sound to ensure its long-term sustainable growth. Livestock wastes mostly manure, can be a valuable resource as well as a potential hazard to environment. The first option of manure management is developing an 'environmentally sound' feeding program and feeds so there are less excreted nutrients that need to be managed. Once the manure is produced it can be best utilized as a fertilizer of a soil conditioner. In many countries the amount of manure that can be spread on land depends on the nutrient requirements of the crop being grown. The laws specify maximum application rates and not animal stocking rates. Farmer who reduce the N and P component of manure can release pressure on the environment without having to reduce the number of animals. There are alternative system for housing and manure treatment which generate manure that are easier to handle and have less pollutants or more economic value. Treated animal waste may also be used as a feedstuff or fuel source. Most of the options of waste management result in increased costs to implement. It is necessary to assess the economics in order to find an acceptable compromise between the increased costs and the benefit to the environment. Animal welfare is also becoming more and more of an issue and it will lead to systems where animals are kept in less confined environment. The new system will have a great impact in the waste management system in the future.

• International journal of advanced smart convergence
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• 제4권1호
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• pp.54-63
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• 2015

Increasing air pollution levels and the global oil crisis has become a major hindrance in the growth of our automobile sector. Traditional Internal Combustion engines running on non-renewable fuels are proving to be the major culprit for the harmful effects on environment. With few modifications and also with assistance of few additional components current small SI engines can be modified into a pneumatic engine (commonly known as Compressed Air Engines) without much technical complications where the working fluid is compressed air. The working principle is very basic as adiabatic expansion of the compressed air takes place inside the cylinder pushing the piston downwards creating enough MEP to run the crank shaft at decent RPM. With the assistance of new research and development on pneumatic engines can explore the potential of pneumatic engines as a viable option over IC engines. The paper deals with analysis on RPM variation with corresponding compressed air injection at different crank angles from TDC keeping constant injection time period. Similarly RPM variation can also be observed at different injection pressures with similar injection angle variation. A setup employing a combination of magnetic switch (reed switch), magnets and solenoid valve is used in order to injection timing control. A conclusive data is obtained after detailed analysis of RPM variation that can be employed in newly modified pneumatic engines in order to enhance the running performance. With a number of benefits offered by pneumatic engine over IC engines such as no emissions, better efficiency, low running cost, light weight accompanied by optimized injection conditions can cause a significant development in pneumatic engines without any major alteration.

• 전기화학회지
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• 제13권4호
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• pp.270-276
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• 2010

기공 경사화된 마이크론 단위의 구조 틀 및 나노 수지상 구조 벽을 가지는 니켈-구리 거품 전극을 전기화학적인 방법으로 합성하였다. 전해 도금 시 순수한 니켈은 치밀한 층으로 성장하는 양상을 보였으나, 구리와 함께 도금시키는 경우 그 성장 양상이 순수한 니켈과는 매우 다르게 관찰되었다. 특히, 첨가제로써 염소 이온의 농도가 증가함에 따라 니켈-구리 도금 층의 수지상 성장이 뚜렷해지는 모습을 보였다. 또한, 기재와 먼 부분일수록 도금 층 내 구리 대비 니켈의 상대적인 양이 감소하였으며, 염소 이온 농도가 높아짐에 따라 전 도금 층에 걸쳐 니켈의 양이 증가하였다. 수지상 구조 벽의 가지 내부 조성을 분석한 결과, 중심부로 갈수록 구리 함량이 점차 높아지는 조성 구배를 확인하였으며, 적절한 열처리를 통해 상호 확산을 유도하여 균일한 조성의 니켈-구리 합금을 얻어낼 수 있었다. 본 연구를 통해 제작된 재료는 기능성 전기 화학 장치용 고성능 전극에 활용될 수 있을 것으로 기대된다.

• 구강회복응용과학지
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• 제33권2호
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• pp.143-153
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• 2017

치아 외상에 따른 흔한 합병증 중 하나는 치아 유착이다. 성인과 달리 성장기 아동에서 유착이 나타날 경우 유착치가 인접 치조골의 성장을 방해하여 치조골의 발육 부전과 이에 따른 개방 교합을 야기한다. 그러나 저위된 유착치를 단순 발치할 경우, 성장 완료 시까지 치조제의 상당한 소실을 유발하여 향후 심미적인 보철물을 수복하기가 어려워진다. 본 증례에서는 성장기에 상악 전치의 유착이 발생한 환자에서 단일 치아 골절단술 후 치조골 신장술과 치관 절제술을 시행하여 상악 전치부의 유착치를 심미적으로 결과를 얻었으므로 소개하고자 한다.