• Title/Summary/Keyword: growth option

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Autotransplantation of Ectopically Impacted Teeth : Two Case Reports (이소매복된 치아의 자가치아이식 증례)

  • Lim, Yuran;Kim, Jaehwan;Choi, Namki;Kim, Seonmi
    • Journal of the korean academy of Pediatric Dentistry
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    • v.44 no.1
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    • pp.108-115
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    • 2017
  • Numerous therapeutic approaches are available for impacted teeth, including orthodontic retraction, implantation, and autogenous tooth transplantation. Autotransplantation is a promising method, especially for juvenile patients, as it enables preservation of the function of the periodontal tissues, as well as continued alveolar bone growth. This report describes autotransplantation in two cases in which the tooth was fully-ectopically impacted. With case 1, an ectopically impacted premolar was extracted and transplanted in an upright position, and regenerative endodontic treatment was performed using a platelet-rich fibrin clot and mineral trioxide aggregate (MTA). With case 2, a calcifying odontogenic cyst with an impacted left mandibular second molar was treated by enucleation. The tooth was transplanted into the proper position 3 months after enucleation, and endodontic treatment was performed using MTA. In both cases, autotransplantation appeared to provide a simple and rapid treatment option for patients with ectopically impacted teeth. These cases demonstrate that autotransplantation of ectopically impacted teeth is a viable treatment option rather than implant placement or prosthesis, especially in juvenile patients.

Purification and Identification of Apoptosis Modulator Pipernonaline from Piper longum Linn. against Prostate Cancer Cells (필발(Piper longum Linn.)로부터 전립선암 세포사멸물질 pipernonaline의 분리 및 동정)

  • Kim, Kwang-Youn;Kim, Yun-Jin;Lee, Wan;Yu, Sun-Nyoung;Cho, Hyo-Jin;Lee, Sun-Yi;Lee, Han-Seung;Sohn, Jae-Hak;Oh, Hyuncheol;Ahn, Soon-Cheol
    • Journal of Life Science
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    • v.19 no.5
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    • pp.671-675
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    • 2009
  • Prostate cancer has been a critical health problem due to an increase of prostate cancer-related deaths worldwide. Also, a frequent treatment option for prostate cancer is androgen ablation, but this treatment has a limited scope, especially for hormone-refractory cancer. There is an urgent need for the identification of alternative therapeutic strategies for prostate cancer. Previously, over one hundred species of dried-plant methanol extracts were tested for inhibitory effects on proliferation. One of them, Piper longum Linn. was selected based on its potent anti-proliferation effect. The dried root of P. longum Linn. was extracted with 100% methanol for 2-3 days and its extract was fractionated using chloroform. The chloroform layer was then subjected to column chromatography on silica gel, reverse phase-18 (RP-18) and Sephadex LH-20, in turn. Finally, the pure compound was obtained and identified as pipernonaline by NMR spectroscopic and physico-chemical analysis. In this study, anti-proliferation and cell cycle arrest effects of pipernonaline on human prostate cancer PC-3 cells were investigated using the MTT and PI staining, respectively. Our findings suggest that pipernonaline represents a dose-dependent growth inhibition pattern on PC-3 cells and, moreover, its growth inhibition is associated with sub-G1 and G0/G1 cell cycle accumulation in PC-3 cells. Also, these results provide an anticancer candidate for human prostate cancer.

A Basic Treatise of Korean Mother′s Concern for the Artificial Feeding (인공영양에 대한 한국 어머니들의 반응에 관한 기초조사)

  • 변수자
    • Journal of Korean Academy of Nursing
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    • v.3 no.1
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    • pp.41-51
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    • 1972
  • In this article, the writer attempted to study the followings: (1) mother's knowledge of milk feeding (including method of sterilization, formula and feeding) (2) reasons of artificial feeding (3) how much mothers are concerned about their artificial feeding infants (4) condition of growth and development of artificial feeding infants. As the object of study, 96 mothers with artificial feeding infants, who had consulted dep't of pediatrics of two Hospitals in Seoul (Korea Hospital and Med. College Woo Suk Hospital, Korea Uni.) and well baby clinic of the two Health Centers (Sung Dong and Dongdaemoon), were randomly sampled. The data were treated by the statistic method of chi-square and percentage, and come to the following conclusion. 1. Knowledge of milk feeding Sterilization: 70 percentages of mothers know about the milk sterilization (including bottle, nipple and instrument), but 55 percentages of them do not know the nipple sterilization correctly. Formula: 69 percentages of mothers follow the indicator or in accordance with doctor's directions, but 31 percentages do at their option by reasons that the baby often coughs up the milk, the baby is too small, the baby often has digestive troubles, or the baby grow fleshy heavily etc, except family economic problems. Feeding: only half of mothers know the correct feeding method, especially they do not know how to determine the heat degree of milk and how to bubble up the baby correctly. They just do feeding according to the accepted usages. 2. Reasons of artificial feeding Of the reasons of artificial feeding, 18 percentages were caused by infants and 82 percentages by mothers. Most of the reasons are mainly due to the lack of breast milk and sufficient supply of nourishments rather than mother's deficiency or mother's abnormality. 3. Mother's concern for artificial feeding infants Mothers who are sharply concerned for their artificial feeding baby's growth and development: 63%, mothers who made the baby (artificial feeding infant) routine vaccinated: 81%, mothers who ear anxious about the baby's future personality forming : 68%, mothers who care about the baby's condition of nourishment; 60%, mothers who are anxious about tile selection of baby's food; 54%. 4. The growth and development of artificial feeding infants compared with Korean average infants. The artificial feeding infants are above the Korean average infants in stature by 1.21 centimeters and in weight by 0.3 kilograms. Conclusion: It has been said that there is no better food for infant than the breast milk. However, the artificial feeding has been used for the supplement of nourishments and as substitute food for the breast milk. And this artificial feeding could give the married women the chance to act in society and more opportunity to develop themselves and to work for others at home and other fields. Considering these advantages, artificial feeding should not be exclusive, but preferably should be more improved and inquired positively. And even in artificial feeding, what is most important is that mothers should recognize the requirement and need of artificial feeding clearly and correctly, and they should be accustomed to the correct knowledge and skills of artificial feeding in order to practice it appropriately. In some degree, they should be properly trained in school education process.

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Neural Growth Factor Stimulates Proliferation of Spinal Cord Derived-Neural Precursor/Stem Cells

  • Han, Youngmin;Kim, Kyoung-Tae
    • Journal of Korean Neurosurgical Society
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    • v.59 no.5
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    • pp.437-441
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    • 2016
  • Objective : Recently, regenerative therapies have been used in clinical trials (heart, cartilage, skeletal). We don't make use of these treatments to spinal cord injury (SCI) patients yet, but regenerative therapies are rising interest in recent study about SCI. Neural precursor/stem cell (NPSC) proliferation is a significant event in functional recovery of the central nervous system (CNS). However, brain NPSCs and spinal cord NPSCs (SC-NPSCs) have many differences including gene expression and proliferation. The purpose of this study was to investigate the influence of neural growth factor (NGF) on the proliferation of SC-NPSCs. Methods : NPSCs ($2{\times}10^4$) were suspended in $100{\mu}L$ of neurobasal medium containing NGF-7S (Sigma-Aldrich) and cultured in a 96-well plate for 12 days. NPSC proliferation was analyzed five times for either concentration of NGF (0.02 and 2 ng/mL). Sixteen rats after SCI were randomly allocated into two groups. In group 1 (SCI-vehicle group, n=8), animals received 1.0 mL of the saline vehicle solution. In group 2 (SCI-NGF group, n=8), the animals received single doses of NGF (Sigma-Aldrich). A dose of 0.02 ng/mL of NGF or normal saline as a vehicle control was intra-thecally injected daily at 24 hour intervals for 7 days. For Immunohistochemistry analysis, rats were sacrificed after one week and the spinal cords were obtained. Results : The elevation of cell proliferation with 0.02 ng/mL NGF was significant (p<0.05) but was not significant for 2 ng/mL NGF. The optical density was increased in the NGF 0.02 ng/mL group compared to the control group and NGF 2 ng/mL groups. The density of nestin in the SCI-NGF group was significantly increased over the SCI-vehicle group (p<0.05). High power microscopy revealed that the density of nestin in the SCI-NGF group was significantly increased over the SCI-vehicle group. Conclusion : SC-NPSC proliferation is an important pathway in the functional recovery of SCI. NGF enhances SC-NPSC proliferation in vitro and in vivo. NGF may be a useful option for treatment of SCI patients pending further studies to verify the clinical applicability.

The Construction and Management of Artificial Wetland Using Emergent Macrophytes for High Biomass Production (대형정수식물을 활용한 높은 생산성의 인공습지 조성 및 관리)

  • Hong, Mun Gi;Heo, Young Jin;Kim, Jae Geun
    • Journal of Wetlands Research
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    • v.16 no.1
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    • pp.61-72
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    • 2014
  • To present a guideline on the construction and management of artificial wetlands for high biomass production, three emergent macrophytes (Phragmites australis, PA; Typha angustifolia, TA; and Zizania latifolia, ZL) were planted under two substrates conditions (general soil with and without moss peat) and two water levels (5 cm and 20 cm) and monitored for three years. ZL showed greater growth performance rather than the others not only at early growth phase in the first year [shoot height, 200 cm; above-ground dry weight (AGDW), 500 $g/m^2$] but also in the last year (ZL, 1,100 $g/m^2$; TA, 770 $g/m^2$; and PA, 450 $g/m^2$ of AGDW). ZL with rapid growth at the early growth phase was not affected by naturally introduced weeds, whereas slower and poorer growth of PA and TA at the early growth phase resulted in relatively higher introduction and establishment of natural weeds. In turn, such introduced weeds negatively contributed to the growth of PA and TA particularly under shallow water (5 cm) with the substrate condition including moss peat. We suggest a plant material with rapid and great growth at the early phase such as ZL for reducing possible negative influences by the natural weeds and wild animals for high biomass production in constructed wetlands. A pre-growing process in greenhouse prior to planting might be an useful option to raise the competitiveness of those species when planting PA and/or TA. In addition, we recommend that integrated weed management system with utilizing various options at the most appropriate timing must be applied for maintaining sustainable high biomass production at the artificial wetlands.

Physiological and Growth Responses of M. thunbergii to Different Levels of Fertilization (시비처리에 따른 후박나무의 생리 및 생장 반응)

  • Jung-Won Sung;Yeong Geun Song;Haeun Koo;Hyeon Hwa Kim;Se Min Byun;Chae Rim Lee;Seok-Gon Park;Kyeong Cheol Lee
    • Korean Journal of Plant Resources
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    • v.36 no.2
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    • pp.172-180
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    • 2023
  • In the current study, four groups; control, 500, 1000, and 2000 mg/L, were treated to investigate the effects of physiological and growth characteristics on Machilus thunbergii under various fertilization levels. As a result of the physiological response to the fertilization treatment, the fertilized group demonstrated relatively higher levels of A, ITE, WUEi, Vcamx, PIabs, and SFIabs in comparison to the control. The best photosynthetic mechanism was most clearly seen at 1000 mg/L, which involved gas exchange through active stomatal opening and closing. For a productive photosynthetic mechanism. As seen in the growth response of M. thunbergii to fertilization treatment, the fertilized group has significantly higher height, DRC, leaf dry weight, stem dry weight, total dry weight, LWR, and SWR than the control group. A healthy seedling quality index was particularly evident at 1000 mg/L, and other growth indicators were also at a decent level. 500 mg /L also demonstrated growth characteristics that were comparable to those at 1000 mg/L. As a result, M. thunbergii featured the best physiological and growth characteristics in response to the fertilization treatment at 1000 mg/L, and 500 mg/L also showed a similar trend, which is considered to be a good option from an economical perspective.

STRATEGIES TO REDUCE ENVIRONMENTAL POLLUTION FROM ANIMAL MANURE: PRINCIPLES AND NUTRITIONAL MANAGEMENT - A REVIEW -

  • Paik, I.K.;Blair, Robert;Jacob, Jacqueline
    • Asian-Australasian Journal of Animal Sciences
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    • v.9 no.6
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    • pp.615-635
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    • 1996
  • The animal industry must be environmentally sound to ensure its long-term sustainable growth. Livestock wastes mostly manure, can be a valuable resource as well as a potential hazard to environment. The first option of manure management is developing an 'environmentally sound' feeding program and feeds so there are less excreted nutrients that need to be managed. Once the manure is produced it can be best utilized as a fertilizer of a soil conditioner. In many countries the amount of manure that can be spread on land depends on the nutrient requirements of the crop being grown. The laws specify maximum application rates and not animal stocking rates. Farmer who reduce the N and P component of manure can release pressure on the environment without having to reduce the number of animals. There are alternative system for housing and manure treatment which generate manure that are easier to handle and have less pollutants or more economic value. Treated animal waste may also be used as a feedstuff or fuel source. Most of the options of waste management result in increased costs to implement. It is necessary to assess the economics in order to find an acceptable compromise between the increased costs and the benefit to the environment. Animal welfare is also becoming more and more of an issue and it will lead to systems where animals are kept in less confined environment. The new system will have a great impact in the waste management system in the future.

ANALYSIS AND OPTIMIZATION of INJECTION TIMING for AN ADVANCED COMPRESSED AIR ENGINE KIT

  • Kumar, Akshay;Kumar, Vasu;Gupta, Dhruv;Kumar, Naveen
    • International journal of advanced smart convergence
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    • v.4 no.1
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    • pp.54-63
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    • 2015
  • Increasing air pollution levels and the global oil crisis has become a major hindrance in the growth of our automobile sector. Traditional Internal Combustion engines running on non-renewable fuels are proving to be the major culprit for the harmful effects on environment. With few modifications and also with assistance of few additional components current small SI engines can be modified into a pneumatic engine (commonly known as Compressed Air Engines) without much technical complications where the working fluid is compressed air. The working principle is very basic as adiabatic expansion of the compressed air takes place inside the cylinder pushing the piston downwards creating enough MEP to run the crank shaft at decent RPM. With the assistance of new research and development on pneumatic engines can explore the potential of pneumatic engines as a viable option over IC engines. The paper deals with analysis on RPM variation with corresponding compressed air injection at different crank angles from TDC keeping constant injection time period. Similarly RPM variation can also be observed at different injection pressures with similar injection angle variation. A setup employing a combination of magnetic switch (reed switch), magnets and solenoid valve is used in order to injection timing control. A conclusive data is obtained after detailed analysis of RPM variation that can be employed in newly modified pneumatic engines in order to enhance the running performance. With a number of benefits offered by pneumatic engine over IC engines such as no emissions, better efficiency, low running cost, light weight accompanied by optimized injection conditions can cause a significant development in pneumatic engines without any major alteration.

Pore Gradient Nickel-Copper Nanostructured Foam Electrode (기공 경사화된 나노 구조의 니켈-구리 거품 전극)

  • Choi, Woo-Sung;Shin, Heon-Cheol
    • Journal of the Korean Electrochemical Society
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    • v.13 no.4
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    • pp.270-276
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    • 2010
  • Nickel-copper foam electrodes with pore gradient micro framework and nano-ramified wall have been prepared by using an electrochemical deposition process. Growth habit of nickel-copper co-deposits was quite different from that of pure nickel deposit. In particular, the ramified structure of the individual particles was getting clear with chloride ion content in the electrolyte. The ratio of nickel to copper in the deposits decreased with the distance away from the substrate and the more chloride ions in the electrolyte led to the more nickel content throughout the deposits. Compositional analysis for the cross section of a ramified branch, together with tactical selective copper etching, proved that the copper content increased with approaching central region of the cross section. Such a composition gradient actually disappeared after heat treatment. It is anticipated that the pore gradient nickel-copper nanostructured foams presented in this work might be a promising option for the high-performance electrode in functional electrochemical devices.

Managements of ankylosed incisor occurred during adolescence using alveolar bone distraction osteogenesis and decoronation: case report (성장기에 발생한 유착치의 치조골 신장술과 치관 절제술을 이용한 심미적 개선 치험례)

  • Kwon, Eun-young;Son, Woo-Sung;Park, Soo-Byung;Kim, Seong-sik;Kim, Yong-il;Choi, Youn-kyung
    • Journal of Dental Rehabilitation and Applied Science
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    • v.33 no.2
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    • pp.143-153
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    • 2017
  • One of the common complications of dental injury is tooth ankylosis. Unlike adults, when tooth ankylosis occurs in the adolescents, ankylosis interfered the growth of the adjacent alveolar bone, resulting in the developmental failure of the alveolar bone and subsequent open bite. The most common treatment option for ankylosed tooth is extraction. However, when prognosis of ankylosed tooth after extraction is expected to be poor due to severity of infrapositioning or prosthetic replacement cannot be performed immediately, various treatment options should be considered. This report suggests multidisciplinary treatment that might bring functionally and esthetically favorable result included alveolar bone distraction osteogenesis and decoronation of ankylosed maxillary anterior tooth with orthodontic and prosthetic treatments.