• Title/Summary/Keyword: growth curve analysis

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Simulation of Dynamic Behavior of Glucose- and Tryptophan-Grown Escherichia coli Using Constraint-Based Metabolic Models with a Hierarchical Regulatory Network

  • Lee Sung-Gun;Kim Yu-Jin;Han Sang-Il;Oh You-Kwan;Park Sung-Hoon;Kim Young-Han;Hwang Kyu-Suk
    • Journal of Microbiology and Biotechnology
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    • v.16 no.6
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    • pp.993-998
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    • 2006
  • We earlier suggested a hierarchical regulatory network using defined modeling symbols and weights in order to improve the flux balance analysis (FBA) with regulatory events that were represented by if-then rules and Boolean logic. In the present study, the simulation results of the models, which were developed and improved from the previou model by incorporating a hierarchical regulatory network into the FBA, were compared with the experimental outcome of an aerobic batch growth of E. coli on glucose and tryptophan. From the experimental result, a diauxic growth curve was observed, reflecting growth resumption, when tryptophan was used as an alternativee after the supply of glucose was exhausted. The model parameters, the initial concentration of substrates (0.92 mM glucose and 1 mM tryptophan), cell density (0.0086 g biomass/1), the maximal uptake rates of substrates (5.4 mmol glucose/g DCW h and 1.32 mmol tryptophan/g DCW h), and lag time (0.32 h) were derived from the experimental data for more accurate prediction. The simulation results agreed with the experimental outcome of the temporal profiles of cell density and glucose, and tryptophan concentrations.

Analysis of Weladbility on Resistance Spot Weld for 3 Steel Sheets of Automotive Car Body Using Simulation Method and Nugget Growth Curve (시뮬레이션 및 너겟 성장 곡선을 이용한 자동차 차체용 3겹 강판의 저항점 용접성 분석)

  • Park, Young-Whan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.9
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    • pp.3155-3160
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    • 2010
  • Nowadays, most car manufactures have tried to improve fuel efficiency and corrosion resistance of car body. Therefore, use of high strength steels and coated steel becomes more and more increased. In this study, spot weld characteristics according to lap sequence of sheets were analyzed using simulation method for three different steel sheet of car body which were EDDQ class coated steel with 0.7t, high strength steel 440R with 1.2t and advanced high strength steel DP 590 with 1.0t. Using simulation, weldability was evaluated by nugget size of welded zone according to nugget growth curve and welding current with respect to lap sequence of sheets. Contact resistance of each sheets contact point was used to analyze formation of nugget and optimal lap sequence was suggested.

Epitaxial Growth of $NdF_3:Er^{3+}/CaF_2(111)$ by MBE

  • Ko, J.M.;Fukuda, T.
    • Proceedings of the Korea Association of Crystal Growth Conference
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    • 1998.06a
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    • pp.71-74
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    • 1998
  • $Er^{3+}$ doped $NdF_{3}$ single crystalline thin films with smooth, microcrack-free, and high-crystalline quality were grown on $CaF_{2}(111)$ substrate at $500^{\circ}C$by molecular beem epitaxy(MBE). The relation-ship between subcell and supercell showing the reconstructed $3^{1/2} \times 3^{1/2}$ structure was studied by reflection high-energy electron diffraction(RHEED) investigation. The film surface and the growth mode were examined in studied by RHEED patterns and atomic force microscope(AFM) images ex situ. The crystallinity of film and the lattice mismatch between $NdF_{3}Er}^{3+}(0002)$ film and $CaF_{2}(111)$ substrate depending in the $Er^{3+}$ concentration were investigated by X-ray rocking curve analysis.

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Properties and Hair-growth Effect of Chrysin 7-O-crotonate (크라이신 7-O-크로토네이트의 물성 및 육모효과)

  • 신준수;김연희;정재훈;김양배;김박광
    • YAKHAK HOEJI
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    • v.43 no.3
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    • pp.316-319
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    • 1999
  • Chrysin 7-Ο-crotonate was synthesized by condensing crotonic acid with chrysin in organic solvent, tetrahydrofuran (THF) using dicyclohexylcarbodiimide (DCC) and 4-dimethylaminopyridine (DMAP). Its structure was indentified by NMR, MS, UV, IR etc. We also investigated the physico-chemical properties and set up the quantitative anytical method of this compound. The correlation coefficient of calibration curve measured at the isobestic point (340 nm) on this compound was approximately 0.9994 by absorption spetrophtometry. Detection limit was 1.6ng at S/N=3 by using a RP column by HPLC. The hair growth effect fo chrysin 7-Ο-crotonate on the hair of black mouse (C57BL/6), was carried out using paste method. When its ethanol solution was administered to this black mouse by route of skin, this compound promoted the growth of hair.

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Growth Analysis of the hard clam, Meretrix petechialis (Lamarck) collected from the Daejuk-ri Shell Middens, Seosan, Korea (서산 대죽리 패총에서 출토된 말백합 Meretrix petechialis (Lamarck)의 성장 연구)

  • Ryu, Dong-Ki;An, Deog-Im
    • The Korean Journal of Malacology
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    • v.29 no.2
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    • pp.121-127
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    • 2013
  • In this study, growth-line analysis was carried out on the hard clam (Meretrix petechialis) collected from the Neolithic shell middens in Daejuk-ri, Seosan, Korea, to reconstruct palaeoenvironment. Growth increments of 206 specimens of the clam were examined. The ages of the specimens were determined from the rings on the shells. The relationship between shell length and ring radius in each ring group was expressed as a regression line, indicating a correspondence in each ring formation. Growth pattern of the midden specimens was compared to that of modern ones collected from Gimje, Jeonbuk. Growth curves for shell length fitted to the von Berta anffy's growth curve were expressed respectively as follows: $SL_t=102.9025[1-e^{-0.18657(t+1.0906)}]$ in the shell midden specimens, $SL_t=104.2583[1-e^{-0.2277(t+0.7499)}]$ in the modern ones. The relationship between shell length (SL; mm) and shell height (SH; mm) was expressed by the following equations: SH = 0.7791 SL + 3.6636 ($R^2$ = 0.946) in the midden specimens, SH = 0.8103 SL + 0.5145 ($R^2$ = 0.991) in the modern ones. The results of the tests regarding the differences between regression coefficients and elevations of growth curves of these two populations demonstrate that the slopes were not significantly different (p < 0.05), but the elevations were (p > 0.05). However, overall growth curves of the midden and modern populations were not significantly different, indicating that shell growth environments of the two areas are similar. Therefore, it is likely that sea temperature near the midden area could be similar to that of present Gimje area, and thus temperature during the period of the midden formation could be higher than presently known.

A Study on Growth and Physiological Characteristic for Families in Open-pollinated Progeny Test Forest of Pinus koraiensis in Kapyung Site (가평지역(加平地域) 잣나무 풍매차대검정림(風媒差代儉定林)의 가계별(家系別) 생장(生長)과 생리적(生理的) 특성(特性)에 관한 연구(硏究))

  • Chung, Dong-Jun;Shin, Man Yong;Jang, Yong-Seok;Chon, Sang-Keun
    • Journal of Korean Society of Forest Science
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    • v.90 no.1
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    • pp.124-132
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    • 2001
  • This study was conducted to reveal the relationship between physiological characteristics and growth by family for open-pollinated progeny stand of Korean white pine in Gapyung site. Average growth performance of total 25 families for 18 years old progeny stand in this study site showed 5.9m in mean height, 8.9cm in mean DBH, $12.0m^2$ in basal area per hectare and $46.5m^3$ in volume per hectare, respectively. By the analysis result of growth performance for all 25 families, family No. 20 showed the most excellent growth and middle in family No. 10. On the other hand, family No. 3 represented the worst growth among the 25 families. The change of seasonal photosynthesis rate by increasing luminous intensity was the same tendency as the growth pattern of all 25 families and showed the same results in all four seasons. In the seasonal analysis, the photosynthesis rate was increased as the season has changed from winter to summer. Chlorophyll contents was also increased from winter to summer. Especially, family No. 20 which is the best in growth performance has more chlorophyll contents than the others. In addition, family No. 20 was also better than other families in the weight of assimilation tissue(g), length of needle(cm), width of needle(cm), and number of Stoma. However, in water utilization rate, family No. 3 which is the worst in the growth performance showed the best result that is reverse tendency compared with the photosynthesis rate. The changes of water utilization rate represented to be increased as the season has changed from winter to summer.

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Age Structure Analysis of Kaloula borealis (맹꽁이(Kaloula borealis)의 나이구조 분석)

  • Ko, Sang-Beom;Lee, Jung-Hyun;Oh, Hong-Shik
    • Korean Journal of Environment and Ecology
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    • v.25 no.6
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    • pp.861-866
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    • 2011
  • Using skeletochronology in the Daejung-eup, Jeju, we determined the age structure of Kaloula borealis. The study was performed during the breed season in June 2009. We measured the snout-vent length(SVL) and body weigth(BW) and analyzed the age structure of 38 male and 58 female frogs. The mean value of SVL is $43.69{\pm}3.44mm$ in males and $46.32{\pm}4.23mm$ in females. The age at first reproduction was estimated to be 2 years of age in males and 3 years in females. The oldest males and females were 8 and 10 years of age, respectively. Therefore, the longevity in this species was estimated to be more than 8 years for males and 10 years for females. So, females live longer than males. Also, this difference between the male and the female in age structure was significant. We estimated the growth curve for Kaloula borealis using von Bertalanffy growth model. The growth coefficient (K) was 0.56 in male and 0.41 in female. The asymptotic size was 46.41 mm in male and 50.22 mm in female.

A Study on the Learning Curve and Productivity (한국 정유산업의 학습곡선과 생산성에 관한 연구)

  • 이종철;강규철
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.20 no.43
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    • pp.175-195
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    • 1997
  • The learning curve has an important effect the growth of corporation. But, in Korea, the study and inference on the learning rate of each industry are unprepared, and so, Korean industires have difficult in productivity and cost. At this point, this study infers the learning rate of the oil industries and investigates the productivity and growth of them. In conclusion, this study presents the direction of the oil industries' development. With the intention of this objects, this study seizes the status which is concerned the total quantity, the operating rate, the plant capacity, the indicators concerning productivity, the investment of R & D and the scales, and then, infers and verifies the relevancy in connection with the learning rate. In the oil industry, the average rate of learning is 65.96% from 1982 to 1994 which the total quantity and the average operation time are used to infer the rate. To observe the low rate within a same period of time, this study takes the consequences that the learning rate is almost indentical with them each year. This steady state is caused by a difference between the employee and the decision maker about the acquirement and assimiliated of technology. When the high-quality technologies posses the environment to applicate in the scene of labor with them, this technology applies to the productivities. As the learning rate increases, the productivity has more effectiveness. The result of analysis about the effectiveness of the learning rate follows that the R & D unfoldes to exist and does not contribute to the growth of the oil industry. To analyze the variables of the growth, such as the learning rate, the investement of R & D, the operating rate and the gross value added to property, plant and equipment, the model is established and examined. The business strategy in the oil industry must be developed to achive the internal growth as well as the external.

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A Study on Technology Forecasting based on Co-occurrence Network of Keyword in Multidisciplinary Journals (다학제 분야 학술지의 주제어 동시발생 네트워크를 활용한 기술예측 연구)

  • Kim, Hyunuk;Ahn, Sang-Jin;Jung, Woo-Sung
    • Journal of the Korean Operations Research and Management Science Society
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    • v.40 no.4
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    • pp.49-63
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    • 2015
  • Keyword indexed in multidisciplinary journals show trends about science and technology innovation. Nature and Science were selected as multidisciplinary journals for our analysis. In order to reduce the effect of plurality of keyword, stemming algorithm were implemented. After this process, we fitted growth curve of keyword (stem) following bass model, which is a well-known model in diffusion process. Bass model is useful for expressing growth pattern by assuming innovative and imitative activities in innovation spreading. In addition, we construct keyword co-occurrence network and calculate network measures such as centrality indices and local clustering coefficient. Based on network metrics and yearly frequency of keyword, time series analysis was conducted for obtaining statistical causality between these measures. For some cases, local clustering coefficient seems to Granger-cause yearly frequency of keyword. We expect that local clustering coefficient could be a supportive indicator of emerging science and technology.

Trajectories of the elderly's life satisfaction after their retirement: A longitudinal Growth Curve Model (은퇴 후 생활만족도의 종단적 변화와 예측요인 : 잠재성장모형을 이용하여)

  • Kim, Dong bae;Yoo, Byung sun;Jeong, Yo han;Oh, Young kwang
    • Korean Journal of Social Welfare Studies
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    • v.44 no.2
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    • pp.169-199
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    • 2013
  • This study has a purpose to analyze trajectories of life satisfaction of the elderly after their retirement and how the characteristics of individual, retirement and family relationship have an effect on the life satisfaction. This study has investigated the Korean elderly, who had been retired, using the data from three waves(1st wave(2005)~3rd wave(2009) of the Korean Retirement and Income Panel(KReIS). Data analysis has been used to identify the predictors of the intercept and slope related to the life satisfaction after retirement, focusing the trajectories of the life satisfaction after retirement and individual characteristics, retirement characteristics and family relationship with application of the growth curve model by Amos 20.0. First, the intercept of the life satisfaction after retirement was somewhat below average. Life satisfaction averagely increased little by little from 1st wave to 3rd wave. Second, by conducting the conditional growth curve model, the study revealed that the intercept of the life satisfaction after retirement is high on individual characteristics(sex, educational level, income, health status) and in retirement characteristics(voluntary retirement) and satisfaction with family relationship and married life). Furthermore, health status, voluntary retirement, and satisfaction with family relationship asserted the meaningful variables in the slope of life satisfaction after retirement.