• Clinical and Experimental Pediatrics
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• v.52 no.2
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• pp.152-158
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• 2009

Reduced fetal growth is independently associated with increased risk of health problems in later life, particularly type 2 diabetes and cardiovascular diseases. Insulin resistance appears to be a key component underlying these metabolic complications. It is suggested that detrimental fetal environment may program insulin resistance syndrome. An insulin-resistant genotype may also result in both low birth weight and insulin resistance syndrome, and it is likely that the association of low birth weight with insulin resistance is the result of both genetic and environmental factors. Early postnatal rapid catch-up growth is closely related to risk for subsequent metabolic diseases. Fat mass is strikingly reduced in neonates born small for gestational age (SGA), and recent data suggest that insulin resistance seen in catch-up growth is related to the disproportionate catch-up in fat mass compared with lean mass. Endocrine disturbances are also recognized in SGA children, but overt clinical problems are infrequent in childhood. Cognitive impairment is reported in some children born SGA, especially those who do not show catch-up growth, in whom early neurodevelopmental evaluation is required. Breast feeding, also known to be protective against the long-term risk of obesity, may prevent some intellectual impairment in SGA children. Calorie-dense feeding does not seem to be appropriate in SGA infants. We must balance the positive effect of nutrition on neural development against rapid fat deposition and the future risk of insulin resistance.

• International Journal of Costume and Fashion
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• v.18 no.2
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• pp.65-83
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• 2018

The purpose of this study was to explore the dynamics of the newly emerging designer fashion market and examine how startup designers reacted to the tension between creativity and business, and how they grew within such dynamics. In-depth interviews were conducted with 22 DFE entrepreneurs and 7 fashion industry experts. The grounded theory was used to analyze data and yield results. Korean new generation of DFEs, attracted by the growing online market opportunities are directly distributing through online channels, targeting the millennial consumers who are pursuing new values at new distribution channels. They show new growth pattern, start with a few key items in the middle and lower price segments, then upscale their design, quality, and price. This study further investigated designers' enterprise orientation shift, which was explored by Mills. Some creativity-oriented designers encountered difficulties in the orientation shift, while designers who demonstrated business characteristics from the startup stage restored the balance by trying to improve both creativity and business. This study discovered a new way for the designer to enter the growth stage. This growth approach is one of the success strategies applicable to designers launching a brand on online platforms in the global market.

• Korean Journal of Environmental Agriculture
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• v.42 no.3
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• pp.211-219
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• 2023

Nutrient balance is an environmental indicator for assessing the potential of sustainable agriculture. Improving the use of arable land is crucial for reducing the nutrient balance. This study monitored soil water content, seepage water, crop growth, and nutrient balance in weighing lysimeters during forage barley (Hordeum vulgare L., "Yeongyang") cultivation from October to April. The study was conducted from 2020 to 2022, and the treatments included forage barley cultivation (clay loam, CL-FC; sandy loam, SL-FC) and bare soils. During the regeneration period (March to April), the soil moisture contents of bare and forage barley-cultivated soils were approximately 30-40% and 18.1-21.8%, respectively. The daily evapotranspiration of forage barley was 6.09 mm. The nitrogen balances for SL-FC and CL-FC were -0.43 to -2.93 g m^-2 and -0.79 to 0.75 g m^-2, respectively, which can be attributed to the higher nutrient uptake of forage barley in SL-FC than in CL-FC. Consequently, the forage barley cultivation in SL-FC can potentially reduce nutrient leaching during the spring rainy season. Furthermore, nutrient balance can be reduced by cultivating forage crops during the winter season.

• Journal of Korean Institute of Industrial Engineers
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• v.11 no.2
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• pp.165-172
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• 1985

Since energy consumption of developing countries is expected to grow rapidly over the coming decades, the oil-importing developing countries are likely to encounter chronic balance-of-payments difficulties. To analyze the quantitative impacts of this problem, we develop a computable model of international trade. This paper presents four alternative cases - varying the assumptions with respect to energy supplies. This shows that relatively small difference in supplies can lead to 100% differences in the energy prices projected for 1990.

• Journal of the Korean Operations Research and Management Science Society
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• v.11 no.2
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• pp.69-78
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• 1986

The outlook for the Civil Service Pension (CSP) program in Korea indicates several problems. First, the balance of the benefit among the pension recipients is not well maintained. Second, the program is running out of funds as benefit increases exceed the growth in revenues. In this article, we analyze these problems by using linear programming model and discuss the alternatives. We propose an addition of the age limit to the benefit eligibility and a reconsideration of the government subsidy's level.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2003.04a
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• pp.364-367
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• 2003

In this paper, we have examined the MTBE cometabolic degradation by pure culture, which is isolated gasoline contaminated aquifer. Propane was more effectively utilized as a growth substrate to oxidize MTBE. Specific substrate degradation rate was Increased with increasing initial propane amount. Respiking propane was enhanced and continued MTBE degradation and TBA observation was supported MTBE degradation. The mass balance of MTBE and TBA indicated that MTBE was oxidized to TBA as well as further oxidation of TBA.

• Proceedings of the PSK Conference
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• 2003.10a
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• pp.29-31
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• 2003

People usually try to take in nutrition component which is necessary for physical growth, developing and maintaining the health through usually balanced dietary life. However in looking over the results of recent national nutrition survey, even if the nation’s average taking in nutrition condition is fairly good, considering the individual cases there has happened a problem about the balance of taking in nutrition due to the wrong dietary life. (omitted)

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.35 no.5
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• pp.287-293
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• 2009

Cell survival is the result of a balance between programmed cell death and cellular proliferation. Cell membrane receptors and their associated signal transducing proteins control these processes. Of the numerous receptors and signaling proteins, epidermal growth factor receptor (EGFR) is one of the most important receptors involved in signaling pathways implicated in the proliferation and survival of cancer cells. EGFR is often highly expressed in human tumors including oral squamous cell carcinomas, and there is increasing evidence that high expression of EGFR is correlated with poor clinical outcome of common human cancers. Therefore, we examined the antiproliferative activity of gefitinib, epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI), in head and neck cancer cell lines. SCC-9, KB cells were cultured and growth inhibition activity of gefitinib was measured with MTT assay. To study influence of gefitinib in cell cycle, we performed cell cycle analysis with flow cytometry. Western blot was done to elucidate the expression of EGFR in cell lines and phosphorylation of EGFR and downstream kinase protein, Erk and Akt. Significant growth inhibition was observed in SCC-9 cells in contrast with KB cells. Also, flow cytometric analysis showed G1 phase arrest only in SCC-9 cells. In Western blot analysis for investigation of EGFR expression and downstream molecule phosphorylation, gefitinib suppressed phosphorylation of EGFR and downstream protein kinase Erk, Akt in SCC-9. However, in EGFR positive KB cells, weak expression of active form of Erk and Akt and no inhibitory activity of phosphorylation in Erk and Akt was observed. The antiproliferative activity of gefitinib was not correlated with EGFR expression and some possibility of phosphorylation of Erk and Akt as a predictive factor of gefitinib response was emerged. Further investigations on more reliable predictive factor indicating gefitinib response are awaited to be useful gefitinib treatment in head and neck cancer patients.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.40 no.4
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• pp.38-45
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• 2017

As the competitiveness of SMEs (small and medium enterprises) is getting more and more improved and globalized, the government provides various consulting services to secure the competitiveness of small and medium firms and support stable growth. However, the assessment of the result from the government's support is generally focused on non-financial factors, such as customer satisfaction and analysis of improvement effect. This paper is in regards to the statistical analysis of how much the government's support in the form of providing consulting services contributes to financial outcomes in terms of profitability and growth. ROA (return on asset) and ROS (return on sales), which are investment profitability and sales profitability respectively, are chosen as an indicator of profitability. For analysis of growth, sales revenue and total asset growth are used. The samples are 44 corporations which are supported by government, and 150 corporations which are selected for comparison, with corporate growth support center program by the Ministry of Trade, Industry, and Energy chosen as the consulting model. After gathering the yearly balance sheets and income statements of the samples from CRETOP, Korea Enterprise Data, the analysis is conducted in the way of identifying the statistical significance of financial difference in the same period between corporates taking consulting services and corporates which have not, and the difference of financial outcomes from the corporates taking consulting services before and after consulting services. As a result, in terms of business growth, it is turned out to have positive difference both in growth ratio and profitability compared to the compared corporations at the significant level. Therefore, it is obvious that the consulting program which government provides to SMEs have direct influence practically to the corporates' management performance.

• Journal of People, Plants, and Environment
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• v.23 no.5
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• pp.507-519
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• 2020

Background and objective: This study analyzed the growth characteristics, in relation to the soil moisture content, of trees planted in an environment with limited soil depth to provide the baseline data for effective irrigation management. Methods: The experimental treatment was divided into soil moisture contents (SMC) of 20%, 15%, 10%, 5%, and 1%, and the respective watering times were set accordingly. As for plant materials, Nandina domestica, Euonymus alatus, Thuja occidentalis, Hibiscus syriacus, Pinus densiflora, and Pyracantha angustifolia, were chosen for this study, because they are highly likely to be used in urban street environments. Results: The minimum irrigation point suitable for each species was determined by considering various aspects of visual quality and water efficiency in terms of plant growth, including characteristics such as height, root diameter, rootlet development, and weight. Our results indicate that N. domestica should be watered so that the moisture content of the soil is of at least 5%, based on the balance between the stem and roots, as well as on visual quality. E. alatus and P. angustifolia are suitable for watering that results in at least 10% SMC, considering the height, root growth, weight, and visual quality of plants. As for T. occidentalis, it showcases moderate growth with a soil moisture content of at least 5%. Finally, the minimum irrigation time required to obtain 15% SMC is appropriate, in terms of plant growth, fresh weight, and visual quality, for H. syriacus and P. densiflora. Conclusion: This study suggested a basic irrigation guideline for container gardens where trees planted in environments with limited soil depth can be managed so that they are visually appropriate and in good condition of growth.