• Journal of the Korean Chemical Society
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• v.31 no.2
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• pp.133-142
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• 1987

Stereoselectivities of (4+2) cycloaddition reactions of cyclopentadiene with the methyl-substituted allenic acids and esters were investigated by application of $\pi$-nonbonded interaction ($\pi$-NBI) theory. 2-FMO method has been found to be adequate for determination of endo selectivities of diene(LUMO)-dienophile (LUMO) interaction in the thermal reactions and diene (HOMO)-dienophile (LUMO) interaction in the Lewis acid catalyzed reactions. $\pi$-isoconjugate diene structure was formed by through-bond interaction of allene moiety with methyl group in the cumulated diene system; the methyl substituent acts as a conjugative chain and causes inter-level narrowing effect of the FMO's. In dienophiles which do not form $\pi$-isoconjugate diene system, methyl group acts merely as an electron donating group. In thermal reactions, the stereoselectivities are controlled by $\pi$-nonbonded secondary orbital interaction ($\pi$-NSOI) of methyl substituent, which behaves similarly as an ethylene molecule.

• Journal of the Korean Geotechnical Society
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• v.36 no.1
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• pp.5-15
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• 2020

Dynamic behavior of pile foundation is significantly influenced by the dynamic interaction between soil and pile. Especially, in the sloping ground, the soil-pile interaction becomes very complex due to different resistance according to loading direction, soil residual displacement and so on. In this study, dynamic centrifuge tests were performed on the piles in the sloping ground. The model structures consisted of a single pile and 2×2 group pile. The soil-pile interaction has been investigated considering various conditions such as slope, single and group piles, and amplitude of input motions. The phase differences between soil and pile displacement and dynamic p-y curves were evaluated. The analysis results showed that the pile behavior was largely influenced by the kinematic forces between soil and pile. In addition, the dynamic p-y curve showed the complex hysteresis loop due to the effect of slope, residual displacement, and kinematic forces.

• 대한공업교육학회지
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• v.33 no.1
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• pp.191-212
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• 2008

The purpose of this study was to show how to organize small groups on the project method class in technical high school. The subjects of this study were two classes including 40 second-year students (20 students in each class) of architecture design course in D technical high school located in Taejeon metropolitan city. The method of this study was to investigate the ego-state by the ego-gram practicing Transactional Analysis. Total 10 small groups were organized. Each group had 4 members. And the same quality of egostate small group was organized by the 4 students who have high score on NP and AC. The different in kind small group was organized by the 4 students, each of whom has NP leading, A leading, FC leading and AC leading score. After the target small group was video- taped, students' verbal interaction was written into transcripts. Their individual states were analysed by the frame of verbal interaction. The result of this study was that the same quality of TAOK small group had more active interaction(110 times) than different in kind small group(87 times). The frequency of complementary transaction was also higher plenty in the same quality of TAOK small group.

• Korean Journal of Clinical Pharmacy
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• v.25 no.3
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• pp.138-144
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• 2015

Objective: It is to evaluate the drug interaction monitoring program as a pilot project to develop a pharmaceutical care model in a medical intensive care unit and to analyze the influencing factors of drug interactions. Method: Electronic medical records were retrospectively investigated for 116 patients who had been hospitalized in a medical intensive care unit from October to December in 2014. The prevalence of adverse reaction with risk rating higher than 'D' was investigated by Lexi-$Comp^{(R)}$ Online database. The factors related with potential drug interaction and with treatment outcomes were analyzed. Results: The number of patients with a potential interaction of drug combination was 92 (79.3%). Average ages, the length of stay in the intensive care unit and the numbers of prescription drugs showed significant differences between drug interaction group and non-drug interaction group. Opioids (14.4%), antibiotics (7.2%), and diuretics (7.2%) were most responsible drug classes for drug interactions and the individual medications included furosemide (6.4%), tramadol (4.9%), and remifentanil (4.5%). There were 950 cases with a risk rating of 'C' (84.6%), 142 cases with a risk rating of 'D' (12.6%), and 31 cases with a risk rating of 'X' (avoid combination) (2.8%). The factors affecting drug interactions were the number of drugs prescribed (p < 0.0001) and the length of stay at intensive care unit (p < 0.01). The patients in intensive care unit showed a high incidence of adverse reactions related to potential drug interaction. Therefore, drug interaction monitoring program as a one of pharmaceutical care services was successfully piloted and it showed to prevent adverse reaction and to improve therapeutic outcomes. Conclusion: Active participation of a pharmacist in the drug management at the intensive care unit should be considered.

• Journal of Urban Science
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• v.6 no.2
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• pp.59-72
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• 2017

Studies on the calculation of accident costs include the approach on calculating damage costs covering all accidents regardless of first or secondary party and the one calculating damage costs generated by a single victim. These two approaches have a limitation of considering a subject for costs analysis as a single entity. In addition, research on estimating the interaction effects caused in the relationship between diverse traffic accident features and factors remains inadequate since most studies focused on calculating costs incurred in a single entity such as a victim, damaged building, or social organization in charge of managing car accident. This study intends to identify the expected range of old age where a specific interaction effect would remain, compare accidents between old age section and the entire age section, and discover an exogenous variable to be applied in accident drop effects in senior people and reduced benefits by calculating and testing additional accident costs in case the first party and the second party all pertain to the senior age section. By classifying the entire accidents caused by old drivers according to the types of cars, significant coefficients representing the influence that affects car accidents according to the characteristics are calculated and set them as the representative variables by selecting top variable in accordance with from low to high order. Furthermore, characteristics on five age groups such as a group of over 65 and less than 70, a group of over 70 and less than 75, a group of over 75 and less than 80, a group of over 80 and less than 85, and a group of over 85 are elicited and compared them with these preselected accident characteristics variables, thereby identifying what changing effects come out.

• Journal of Ecology and Environment
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• v.33 no.3
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• pp.245-251
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• 2010

We evaluated the interaction between Cd and Zn in the bioaccumulation of seven clones of Salix caprea, which were exposed both to Cd and Zn alone and to a combination of Cd and Zn. Cadmium (Cd) and Zn concentration in the four treatments were administered in the following order: root > leaf > stem, and obvious differences were noted among the treatments and clones. The leaf Cd concentration of clone BH2 and stem Cd concentration of clone BH5 in the combined Cd and Zn treatment group was increased by 62% and 110%, respectively, relative of that of the Cd alone treatment group. On the other hand, the leaf and stem Zn concentration of clone BH8 in the combined Cd and Zn treatment group was reduced by 66% and 61%, respectively, relative to that of the Zn alone treatment group. Translocation of Cd and Zn from the root was higher in the leaf than in the stem, and the combined Cd and Zn treatment stimulated the translocation of Cd from the root to the leaf and stem, whereas it suppressed the translocation of Zn from the root to the leaf and stem. Therefore, the interaction effects were considered strongly synergistic with Cd in the presence of Zn, but proved antagonistic to Zn in the presence of Cd in the combined Cd and Zn treatment group. The phytoremediation potentials of the seven clones, which were estimated from standard indices of Cd and Zn concentration in Cd and Zn alone and the combined Cd and Zn treatment groups, were highest in clone BH3, and lowest in clone BH5. Therefore, we recognize S. caprea as an appropriate material for phytoremediation, and this is particularly the case with clone BH3. However, further research will be required to evaluate the effects of Cd and Zn on the physiological changes as well as tolerance mechanisms against metal toxicity in S. caprea clones.

• The Korean Journal of Pain
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• v.18 no.1
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• pp.1-9
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• 2005

Background: Spinal metabotropic glutamate receptors (mGluRs) and opioid receptors are involved in the modulation of nociception. Although opioid receptors agonists are active for pain, the effects of the compounds for the mGluRs have not been definitely investigated at the spinal level. We examined the effects of the intrathecal mGluR compounds and morphine in the nociceptive test, and then we further clarified the role of the spinal mGluRs. In addition, the nature of the pharmacological interaction after the coadministration of mGluRs compounds with morphine was determined. Methods: Catheters were inserted into the intrathecal space of male SD rats. For the induction of pain, $50{\mu}l$ of 5% formalin solution or a thermal stimulus was applied to the hindpaw. An isobolographic analysis was used for the evaluation of the drug interaction. Results: Neither group I mGluR compounds nor group III mGluR compounds produced any antinociceptive effect in the formalin test. The group II mGluR agonist (APDC) had little effect on the formalin-induced nociception. The group II mGluR antagonist (LY 341495) caused a dose-dependent suppression of the phase 2 flinching response on the formalin test, but it did not reduce the phase 1 response of the formalin test nor did it increase the withdrawal latency of the thermal stimulus. Isobolographic analysis revealed a synergistic interaction after the intrathecal delivery of a LY 341495-morphine mixture. Conclusions: These results suggest that group II mGluRs are involved in the facilitated processing at the spinal level, and the combination of LY 341495 with morphine may be useful to manage the facilitated pain state.

• Proceedings of the KSME Conference
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• 2004.11a
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• pp.79-84
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• 2004

Strain energy due to the mechanical interaction between self-accommodation groups of martensitic phase transformation is called interaction energy. Evaluation of the interaction energy should be accurate since the energy appears in constitutive models for predicting the mechanical behavior of shape memory alloy. In this paper, the interaction energy is evaluated in terms of theoretical formulation and explicit finite element calculation. A simple example with two habit plane variants was considered. It was shown that the theoretical formulation assuming elastic interaction between the self-accommodation group and matrix gives larger interaction energy than explicit finite element calculation in which transformation softening is accounted for.

• Korean Management Science Review
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• v.26 no.2
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• pp.37-59
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• 2009

Electronic brainstorming (EBS) to improve the process and outcomes of group decision making is an artifact of Information Systems legacy. Despite three decades of research with EBS in an effort to become a key resource of organizational performance, its performance when compared to that of nominal is inconclusive because of the recent debate over its usefulness in terms of productivity. Subsequent researchers have directed our attention to the re-examination of cognitive stimulation, which is considered the major benefit in computer-based idea generation, to explain the performance singularity in computer-based groups. While both cognitive and motivational factors that moderate and mediate the group-interaction process remain unexplored, individual differences that are tightly linked to creative behavior have been largely ignored to account for the discrepancy in performance. Since simulations have been widely used in situations where an outcome does not meet the assumptions, the notion of a group simulator and detailed simulation mechanisms are introduced to examine the potential effects of individual differences on the performance of computer-based idea generation groups. In addition, two prior studies that empirically explored cognitive mechanisms with the group simulator are showcased along with six propositions to initiate future research.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.11a
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• pp.426-427
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• 2007

Here we describe the formation of a self-assembled film of thin multiwalled carbon Nanotubes(t-MWNT) modified with hydroxy groups through hydrogen peroxide treatment. Morphologies of t-MWNT films could be controlled by the various coating method, such as filtering, drop casting, spraying method, etc. The results show that on densification of the CNT suspension during drying, multiple hydroxy group-modified MWNTs can be self-assembled through strong surface hydrogen bond interaction while MWNTs usually exist an entangled state in the film. The interaction between t-MWNT was illustrated from Raman spectrum of spray coated films.