• Journal of Veterinary Clinics
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• v.20 no.1
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• pp.66-73
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• 2003

Numerous physiological effects are attributed to conjugated linoleic acid(CLA). The purpose of this study is to consider these effects with respect to the cis-9, trans-11 and trans-10, cis-12 CLA isomer. Both isomers are natural products. The c9,t11-CLA isomer is the principal dietary form of CLA, but the concentrations of this isomer and the t10,c12-CLA Isomer in dairy products or beef vary depending on the diet fed to cows or steers, respectively. The influence of dietary CLA isomers on the immune response was examined, body weight and weight ratio of organ to body of Balb/C mice. Mice were divided into four groups of 8 mice. Balb/C mice were fed the experimental diets supplemented with 1% CLA (c9,t11-CLA isomer : t10,c12-CLA isomer = 2:3) (Group 1), 1% CLA (c9,t11-CLA isomer t10,c12-CLA isomer : 1:1) (Group 2), 1% safflower oil (Group 3) or nothing (Control) for 3 weeks. After 3 weeks, serum, gut lumen lavage, fat, liver, spleen and thymus were taken. Measurement of total immunoglobulin were executed using sandwich ELISA. Serum levels of IgA and IgM showed that group fed with t10,c12-CLA isomer significantly were higher than group fed with c9,tl1-CLA isomer. In addition serum level of IgG showed that group fed with t10,c9-CLA isomer significantly were lower than group fed with c9,tl1-CLA isomer. However, no significantly differences were observed in the serum IgE and secretory IgA. Weight ratio of spleen to body showed no significant differences. In weight ratio of liver and thymus to body, tl0,c9-CLA isomer significantly were respectively higher than group fed with c9,t11-CLA isomer. In weight ratio of fat to body, tl0,c9-CLA isomer significantly were respectively lower than group fed with c9,tl1-CLA isomer. In conclusion, t10,c12-CLA isomer produced a situation favorable for immunopotentiative effect and body composition. But it should be protected against hepatomegaly induced lipid accumulation in liver.

• Journal of the Korean Society of Food Science and Nutrition
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• v.22 no.6
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• pp.692-701
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• 1993

This study was designed to examine effects of the various levels of sardine and safflower oil mix on lipid contents of serveral tissues in dietary hyperlipidemic rats. Experimental oils were 16% butter(control group), 8% butter+8% olive oil(group 2), 8% butter+8% sardine oil(group 3), 8% butter+6% sardine oil+2% safflower oil(group 4), 8% butter+4% sardine oil+4% safflower oil(group 5), 8% butter+2% sardine oil+6% safflower oil(group 6) and 8% butter+8% safflower oil(group 7). The diet administered to the male rats of Sprague-Dawley were fed for 4 weeks. In the fatty aicd composition of brain phospholipid, n-3 EPA and DHA contents were increased, and DHA content was remarkably high in the phosphatidylethanolamine(PE) component. Arachidonic acid content were high in the cardiolipin component. In the fatty acid composition of heart phospholipid, PUFA contents were highest in the group 5 and DHA content was higher in the groups 4 and 5, particularly. Fatty acid composition of spleen lipid showed that n-3 EPA and DHA contents were higher in the group 3 than in the other groups.

• Korean Journal of Ichthyology
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• v.33 no.2
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• pp.95-106
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• 2021

In order to understand the seasonal variations of species composition of fish in the Goseong, middle East Sea of Korea, we surveyed fish fauna using set net during 2 years. In this study, a total of 77 taxa belonging to 40 families were collected and 75 species were identified. The dominant family were Tetraodontidae and Pleuronectidae, and the dominant species were Arctoscopus japonicus, Konosirus punctatus, Stephanolepis cirrhifer, Thamnaconus modestus, and Trachurus japonicus. The results of the hierarchical clustering using the number of individuals of collected species showed that they are divided into three seasonal groups: Group A (Jan.~Apr.), Group B (May~Jun., Nov.~Dec.), Group C (Jul.~Oct.). The sea surface temperature (SST) was higher than the results of previous studies in winter and spring, and species composition in spring have changed from cold-water species to the warm-water species, recently. The species composition has become similar to the that of southern Gangwon-do regions (Samcheok and Gangneung) of the previous studies. The species diversity of family Tetraodontidae has increased, which is estimated to have an effect on increase in SST and the quantity of entering the East Sea. Therefore, we assumed that the change of species composition is related to the extension of northern distribution limits and survival temperature, and abundant preys. Therefore, it is necessary that an efficient resource management policy as well as the ways of commercially use of migratory warm-water fish, rapidly.

• Journal of Life Science
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• v.18 no.8
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• pp.1154-1158
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• 2008

The purpose of this study was to analyze the effect of body composition, leptin, total cholesterol and BMD on a long-term exercise paticipation in middle-aged women. Twentieth subjects were divided into three groups, obesity group, over-fat group and normal group. These data were analyzed by One-way ANOVA and Corelation Analysis. Obesity group was higher than over-fat group in body fat volume (p<.001). Obesity group was higher than other groups in BMI (p<0.05). Normal group was higher than obesity group in radius BMD (p<0.01). Body fat was positively correlated with BMI (Rsq=0.8411) and radius BMD (Rsq=0.6736). but, BMI was negatively correlated with tibia BMD (Rsq=0.6714).

• Journal of Nutrition and Health
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• v.36 no.6
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• pp.577-588
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• 2003

Severe protein-calorie malnutrition, common in patients with advanced liver disease, can seriously undermine the capacity for regeneration and functional restoration of liver. Nutritional supplementation for these patients can improve biochemical and hormonal abnormalities. However, these effects were not identified in patient with nonalcoholic liver cirrhosis. To determine effects of nutritional supplementation in patients with nonalcoholic liver cirrhosis, 77 subjects aged 29 to 69 years participated in this study for 12 weeks and were subdivided into three groups; normal diet group (Control group, n ＝ 16), branched-chain amino acid supplementation group (BCAA group, n ＝ 31), nutritional supplementation group (NS group, n ＝ 30). Anthropometric parameters, hemoglobin, hematocrit, blood cell counts, serum levels of lipids, vitamins, minerals and fatty acid composition, and plasma amino acids were examined. The mean values of age and height, and the initial values of weight and body mass index (BMI) were not different among all groups. After 12 weeks, there were no significant changes in these values in Control group. Only NS group showed significant increases in weight, lean body mass, midarm circumference, triceps skinfold thickness. Serum transferrins were increased both in BCAA and NS groups. Plasma levels of branched-chain amino acids, urea amino acids and glutamic acid were also significantly increased in these groups, but plasma levels of ammonia, serum LDL cholesterol and atherogenic index were decreased. However, there were no significant changes in serum levels of vitamin and mineral and composition of fatty acids in phospholipids in these groups. These results showed that the nutritional supplementation for patients with nonalcoholic liver cirrhosis can more improve nutritional status in these people together with increases of weight, body fat and lean body mass, compared to only BCAA supplementation. To ascertain and investigate the appropriate nutritional supplementation for patients with nonalcoholic liver cirrhosis, further studies are necessary.

• The Journal of Pediatrics of Korean Medicine
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• v.23 no.1
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• pp.95-113
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• 2009

Objectives This study was investigated to find how the orally administrated Moschus, herbal combination with Moschus, and herbal combination improves the rats' memory and rats' liver. These medications are generally known asthe memory improvement. Methods This study used the Sprague Dawley rats. They were divided into two groups - SD rats and orally administrated Saline(Control group). 0.473 mg/kg Moschus(HM-A), 153.9 mg/kg herbal composition without Moschus(HM-B), and 165.95 mg/kg herbal composition with Moschus combined(HM-C) Control, saline were orally administered. Each group was trained in the eight-arm radial maze task at the conditions of before oral administrated, and also right after third, sixth, and eighth by oral administration. Lastly, these animals were killed and were tested for brain tissue and serum AST/ALT level to measure how the medications were effected to the liver function. Results The result of radial eight-arm maze task test, the HM-B and HM-C groups showed significant decrease in mistakes from the fourth day of testing. Whereas, the HM-A group showed increasing in the error rate. HM-A and HM-C group of rats had significantly increased amount of acetylcholinesterase in the CA1 region of hippocampus, compared to the control group. Whereas, HM-B and HM-C group had increased level of ChAT compared to the control group. On the other hand, each experimental group did not show any significant difference to the level of serum AST/ALT and the weight ratio of the liver to the body. Conclusions This study provided evidences that the orally administered memory improvement herbal medication, and Moschus were effective to improve memory.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.22 no.2
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• pp.176-185
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• 2009

Objective: The aim of this study was to investigate the correlation between atopic dermatitis and a comprehensive diagnosis of Qi Blood Water in children with or without atopic dermatitis. Methods: We surveyed 206 children in Seoul Jungnang-gu nursery by reviewing the questionnaires following a medical examination. Comprehensive diagnosis of Qi Blood Water was investigated by questionnaires and composition scores and total scores were calculated from the symptom scores. Atopic dermatitis was diagnosed by ophthalmo.otolaryngo.dermatologist and atopic dermatitis symptom was measured by a Visual analogue scale(VAS). Comparisons between the atopic and non-atopic groups were made based on the atopic dermatitis symptom scale, composition scores and total scores. Results : 1. Of the 206 patients, 153(74.27%) were included in the non-atopic group, while 53(25.73%) were included in the atopic group. There was no difference in average age between the two groups. 2. The atopic dermatitis symptom scale of atopic group(3.21$\pm$2.018) was significantly higher than that of non-atopic group(0.04$\pm$0.28). 3. Qi deficiency, Qi stagnation, Blood stasis and Water congestion scores and the total scores of the atopic group were higher than those of the non-atopic group, but it was not significant. 4. The Qi regurgitation and Blood deficiency scores of atopic group were significantly higher than those of the non-atopic group. 5. There was a highly significant correlation between the atopic dermatitis symptom scale and Qi regurgitation scores, and between the atopic dermatitis symptom scale and Blood deficiency scores. Conclusion : Atopic dermatitis seems to have a special feature reflecting the state of comprehensive diagnosis of Qi regurgitation and Blood deficiency in children.

• Journal of Korean Academy of Nursing
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• v.36 no.8
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• pp.1359-1366
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• 2006

Purpose. This study was done to determine the effects of weight management program using self-efficacy in middle-aged obese women. The study also attempted to measure the effects of the program on the weight efficacy lifestyle, body composition, and depression. Method. The research design of this study was a nonequivalent control group pretest-posttest design. The experimental group consisted of 21 middle-aged obese women and another 21 middle-aged obese women in the control group. The women in the experimental group participated in the weight management program for 12 weeks using self-efficacy. The weight management program using self-efficacy included education on effects of exercise for weight control, aerobic exercise program, muscle training and counseling through the telephone. Results. After 12 weeks of participation in the program, BMI (p <.0001), body fat % (p <.0001), abdominal fat (p <.0001), in the experimental group were significantly decreased compared to the control group. Weight self-efficacy lifestyle (p <.0001) and depression (p =.006) in the experimental group were significantly improved after the program compared to the control group. According to these findings, weight management program self-efficacy for middle-aged obese women could increase weight efficacy lifestyle, and decrease depression, BMI, body fat, and abdominal fat. Conclusion. The result also suggested that the increasing weight efficacy and lifestyle help the obese women to perform and continue exercise. This program could be used in the community such as public health center for weight care and mental health promotion of middle-aged obese women.

• The Journal of Korean Physical Therapy
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• v.3 no.1
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• pp.75-90
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• 1991

This study is to characterize the effects of swimming exercise on the composition of muscle fibers in rats lower limb tissue. By comparing the exercised group (4, 8 weeks) with the control group, we analyzed the difference histologically, histochemically and morphometrically. The obtained results are as follows ; 1. In the histological view, the distance between the individual muscle fibers and the muscle bundles in exercised group was shorter than that of control group. The irregular shape of sarcolemma in exercised group was observed. 2, In the histochemical view(NADH-TR. and Myosin ATPase reaction analysis), the increased populations of red and intermediate fibers were observed, whereas the white fiber was decreased. 3. In the morphometrical view, the red and intermediate fibers of tibialis anterior and gastrocnemius in exercised group were quantitatively increased, compared with control group. However, the white fiber and connective tissue in exercised group were decreased.

• Journal of Nutrition and Health
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• v.3 no.2
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• pp.81-85
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• 1970

These experiments were designed to study the influence of protein undernutrition during lactation period(3 wks) or after-weaning period(8 wks) on growth of organs, and on brain and liver composition of the experimental rats. The following experimental groups were studied. Group No. Rats Lactation(3 wks) (Diet of mother rat) After-weaning period(8wks) Rehabilitation Period(17wks) I 8 25% Casein diet 25% Casein diet 25% Casein diet II 8 12% Casein diet 25% Casein diet 25% Casein diet III 8 25% Casein diet 5% Casein diet 25% Casein diet IV 8 12% Casein diet 5% Casein diet 25% Casein diet After the perriod of rehabilitation(17 wks) with 25% casein diet, the following results were obtained. 1. Most of the organs except the spleen could not catch up with the normal group in their weights for the group of protein undernutrition during lactation(3 wks), even after 17 weeks of rehabilitation. For the group of protein undernutrition during after-weaning period(8 wks) brain, lung, heart, spleen and pancreas could catch up with the normal group after rehabilitation. According to this result it is assumed that the growth of brain, lung, heart and pancreas might be developed mostly during lactation and that the growth of liver and kidney might be developed after-weaning period continuously. 2. For the groups of protein underuntrition during lactation period or after-weaning period the amounts of total lipid, cholesterol and phospholipid of brain were lower than those of normal group. Especially, cholesterol level was significantly lower than normal group. And there was also a significant difference in the phospholipid level of the after-weaning(8 wks) deprivation group. 3. The groups of protein undernutrition during lactation or after-weaning period(8 wks) showed lower level of liver nitrogen and higher level of liver fat. Especially, protein undernutriton during lactation gave a greater influence on the lever of liver fat.