• 제목/요약/키워드: gravity measurement

검색결과 214건 처리시간 0.032초

크로마토그래피를 이용한 Paclitaxel 정제에서 비중 조절에 의한 Eluent 재사용 (Reuse of Eluent by Controlling its Specific Gravity during the Chromatographic Purification of Paclitaxel)

  • 김진현
    • KSBB Journal
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    • 제22권5호
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    • pp.366-369
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    • 2007
  • 본 연구에서는 식물세포배양으로부터 회수한 식물세포, 즉 biomass로부터 항암제 paclitaxel를 정제하기 위한 크로마토그래피 공정에서 컬럼을 통하여 용리되는 eluent의 비중 (specific gravity) 조절에 의한 eluent 재사용 방법을 개발하였다. 크로마토그래피 조업 전에 eluent (methanol/water = 70/30, v/v)의 비중을 측정한 결과 0.853을 얻었다. 컬럼으로부터 분취한 용액을 증발 건조하여 건조된 제품과 증발된 용액인 eluent를 각각 회수하였다. HPLC 분석을 통하여 증발/회수된 eluent에 불순물이 포함되어 있지 않음을 확인하고, 회수된 eluent의 비중을 측정하여 비중이 0.853에서 벗어났을 경우에는 메탄올 또는 물을 첨가하여 eluent의 비중을 0.853으로 조정하여 eluent로 재사용하였다. 회수된 eluent를 재사용하여 크로마토그래피 정제를 실시한 결과, 고순도 ($\sim$95%), 고수율 ($\sim$86%)의 paclitaxel을 얻을 수 있었다. 이는 eluent를 재사용하지 않을 경우, 즉 재사용 전과 동일한 수준의 결과로 비중 조절에 의한 eluent의 재사용이 성공적임을 알 수 있었다.

연축전지 양극기판의 기계적 특성비교 분석 및 비 파괴 평가기법의 적용 (Material Evaluation of Lead Die-Casted Positive Grid for Battery Using Nondestructive Evaluation Technique)

  • 김희중;이민래;이준현
    • 대한기계학회논문집A
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    • 제26권8호
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    • pp.1709-1718
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    • 2002
  • It is well recognized that improving capacity of positive grid in battery is one of key factors for controlling the expected long lift-time of Battery Energy Storage System(B.E.S.S). Thus it is really important to characterized material properties of positive grid which are mainly affected by fabrication process. In this study, two kinds of positive grids, which were fabricated by gravity casting and die-casting technique were used. Micro-structural observation and tensile test were conducted to investigate the effect of fabrication process of positive grid. Ultrasonic measurement based on pulse-echo method and ultrasonic C-scan technique also performed to correlate ultrasonic velocity with porosity ratio in positive grid. It was found that the porosity ratio of grid fabricated by gravity casting technique increased significantly compared to the grid fabricated by die-casting technique. It was also shown that ulrasonic technique is effective to evaluate the porosity ratio in positive grid.

An investigation on the in si.tu measurement of the oil-concentration

  • Kim, Chang-Nyeun;Park, Young-Moo
    • International Journal of Air-Conditioning and Refrigeration
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    • 제9권1호
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    • pp.20-28
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    • 2001
  • In order to predict thermodynamic performance of refrigeration system, it is required to know the oil concentration of the refrigerant/oil mixture. The current method is to extract the working mixture and then to measure the oil weight. In this study, oil concentration is measured in si.tu way without any extraction of the working fluid. Based on the measurement, a working equation is presented as follows, C=a +b x t +c x $t^2$ +(d + e x t +f x $t^2$) x SG. C is oil concentration, t is temperature($^{\circ}C). SG Is specific gravity of mixture and a~f is coefficients The oil concentration ranges over 0~l2 wt% and the temperature ranges over 20~50$^{\circ}C. The specific gravity and temperature are measured using the on-line densimeter and thermometer. This working equation enables to predict the oil concentration without any extraction of the mixture. This equation can be applied for R-12/Naphthenic oil and R-134a/P0E oil liquid mixtures.

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An investigation on the in si.tu measurement of the oil-concentration

  • Kim, Chang-Nyeun;Park, Young-Moo
    • International Journal of Air-Conditioning and Refrigeration
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    • 제8권2호
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    • pp.80-88
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    • 2000
  • In order to predict thermodynamic performance of refrigeration system, it is required to know the oil concentration of the refrigerant/oil mixture. The current method is to extract the working mixture and then to measure the oil weight. In this study, oil concentration is measured in si.tu way without any extraction of the working fluid. Based on the measurement, a working equation is presented as follows, C=a +b x t +c x $t^2$ +(d + e x t +f x $t^2$) x SG. C is oil concentration, t is temperature($^{\circ}C). SG Is specific gravity of mixture and a~f is coefficients The oil concentration ranges over 0~l2 wt% and the temperature ranges over 20~50$^{\circ}C. The specific gravity and temperature are measured using the on-line densimeter and thermometer. This working equation enables to predict the oil concentration without any extraction of the mixture. This equation can be applied for R-12/Naphthenic oil and R-134a/P0E oil liquid mixtures.

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중력효과와 받음각 효과에 따른 초공동 형상 중심선 변화에 관한 연구 (A study on the shape of supercavitation center line change according to the gravity and angle of attack effect)

  • 이종주;김민재;백부근;김경천
    • 한국가시화정보학회지
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    • 제20권1호
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    • pp.18-28
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    • 2022
  • In this study, a cavity shape measurement experiment was conducted by changing the diameter and the angle of attack of a disk cavitator. Since the gravity effect is proportional to the cavity volume, the larger the cavity, the greater the effect. It is concluded that the gravity effect becomes smaller as the cavitation number decreases because of a short cavity maintaining time. The cavity centerline rises in case of the positive angle of attack and descends in case of the negative angle of attack. Since the effect of the angle of attack is inversely proportional to the square of the cavity radius, the effect of the angle of attack becomes dominant in the vicinity of the cavitator. It is judged that the horizontal section of the cavity centerline cannot be extended because the factors affecting the gravity effect and the angle of attack effect are different.

자동차 대체연료로서의 Indolene-MPHA의 적용에 관한 연구(I) - Indolene-MPHA 연료의 물성치 특성 - (A Study on the Application of Indolene - MPHA for Automotive Engine (I))

  • 이민호;오율권;차경옥
    • 에너지공학
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    • 제12권3호
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    • pp.184-189
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    • 2003
  • 본 논문은 Indolene-Methanol Plus Higher Alcohols(MPHA)의 연료 특성에 관한 연구로서, 연료의 물성치를 측정하여 조사하였다. 특히 연료의 물성치 중에서 증류특성, 발열량, 인화점, 비중 및 내수성 등을 조사하여 나타내었다. 이때 알콜의 농도는 청정 Indolene의 용적에 따라서 0 에서부터 100%까지 변화하였다. 연료 물성치 측정에서 Indolene-MPHA 혼합물들이 일반적으로 Indolent-Methanol 혼합물과 비교해서 높은 내수성, 유사한 비중과 인화점, 서로 다른 증류특성을 가지고 있음을 알 수 있다. 여기에서 혼합물 물성치 중 상당수는 실제 값과 비교하여 성분들의 중량비를 사용하여 계산하였다.

링레이저 자이로의 플렉셔 각도측정과 플렉셔 오차개선 연구 (Study on flexure angle measurement of ring laser gryo and the improvement of flexure error)

  • 조민식;김광진;김정주
    • 한국광학회지
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    • 제15권1호
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    • pp.68-73
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    • 2004
  • 간섭계를 이용한 링레이저 자이로의 플렉셔 각도 측정기법이 연구되었다. Dummy mass를 추가하여 중력가속도 이상의 고가속도 환경을 구현하였으며, 이에 따른 피에조 간섭무늬의 변화로부터 자이로 입력축의 단위 중력가속도에 대한 플렉셔 각도 변화를 조사하였다. 링레이저 자이로가 가지는 플렉셔 각도 변화계수는 2.37 arcsec/g로,플렉셔 측정 반복도 오차는 0.07arcsec/g정도로 측정되었다. 플렉셔 각도를 감소시켰을 때, 링레이저 자이로 관성항법장치의 플렉셔 오차가 뚜렷이 개선됨을 확인하였다.

3점 측정방식을 사용한 무게중심의 정밀 측정 (Precise Measurement of Center of Gravity Using 3-Point Weighing Method)

  • 유이준;이선표
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 2006년도 춘계학술대회 논문집
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    • pp.283-284
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    • 2006
  • In this paper 3-point weighing method is adopted to measure the unbalance moment of small-sized precision spinning elements using electronic scales with 0.1 mgf resolution. Firstly methods to eliminate the fixture error and to reduce the effects of frictional force that is known as side effect, are proposed. A measuring system is developed and various experiments are performed to verify the proposed approach. The measured and calculated values are analysed in statistical methods, and this provides the errors of the measuring system. The results show that the proposed theory and test procedures gives reliable unbalance moments and gravitational centers.

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인돌렌-메탄올 대체연료의 연료 특성과 엔진성능에 관한 연구 (A Study on the Fuel Characteristics and Engine Performance of Indolene - Methanol Alternative Fuel)

  • 이민호;오율권;차경옥
    • 한국분무공학회지
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    • 제9권4호
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    • pp.9-16
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    • 2004
  • A study of the propeny and performance effect of Indolene - Methanol Plus High Alcolhols (MPHA) has been completed. This study invested the measurement of fuel properties and performance parameters. The fuel properties investigated are distillation characteristics, heating valuer flash point, specific gravity and water tolerance. The performance parameters measured are minimum advance for best torque (MBT) spark timing, power output. The alcohol concentration was varied from 0 to 100 percent by volume in clear Indolene. The measurement of fuel properties indicated that, in general, Indolene - MPHA blends have higher water tolerance, similar specific gravity, similar flash point and different distillation characteristics compared to Indolene - Methanol blends. The performance parameters were measured using a single cylinder spark ignition engine at different compression ratios. The results of the performance measurements indicated that Indolene - MPHA blends have a higher MBT spark advance, similar power output.

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