• Title/Summary/Keyword: graves

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Assessing the Parasitic Burden in a Late Antique Florentine Emergency Burial Site

  • Roche, Kevin;Pacciani, Elsa;Bianucci, Raffaella;Bailly, Matthieu Le
    • Parasites, Hosts and Diseases
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    • v.57 no.6
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    • pp.587-593
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    • 2019
  • Excavation (2008-2014) carried out under the Uffizi Gallery (Florence, Italy) led to the discovery of 75 individuals, mostly buried in multiple graves. Based on Roman minted coins, the graves were preliminarily dated between the second half of the 4th and the beginning of the 5th centuries CE. Taphonomy showed that this was an emergency burial site associated with a catastrophic event, possibly an epidemic of unknown etiology with high mortality rates. In this perspective, paleoparasitological investigations were performed on 18 individuals exhumed from 9 multiple graves to assess the burden of gastrointestinal parasitism. Five out of eighteen individuals (27.7%) tested positive for ascarid-type remains; these are considered as "decorticated" Ascaris eggs, which have lost their outer mammillated coat. Roundworms (genus Ascaris) commonly infest human populations under dire sanitary conditions. Archaeological and historical evidence indicates that Florentia suffered a period of economic crisis between the end of 4th and the beginning of the 5th centuries CE, and that the aqueduct was severely damaged at the beginning of the 4th century CE, possibly during the siege of the Goths (406 CE). It is more than plausible that the epidemic, possibly coupled with the disruption of the aqueduct, deeply affected the living conditions of these individuals. A 27.7% frequency suggests that ascariasis was widespread in this population. This investigation exemplifies how paleoparasitological information can be retrieved from the analysis of sediments sampled in cemeteries, thus allowing a better assessment of the varying frequency of parasitic infections among ancient populations.

Graves' Disease Patients with Large Goiters Respond Best to Radioactive Iodine Doses of at Least 15 mCi: a Sonographic Volumetric Study

  • Jeong, Yun Ah;Yoon, Jee Hee;Kim, Hee Kyung;Kang, Ho-Cheol
    • International journal of thyroidology
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    • v.11 no.2
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    • pp.137-142
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    • 2018
  • Background and Objectives: Radioactive iodine therapy (RAI) is an important treatment modality of Graves' disease (GD), but there is still not a consensus on the optimal dosage regimen. We studied the treatment success rate of different RAI doses, and examined which clinical markers were useful for determining the optimal RAI dosage for successful therapy in Korean patients. Materials and Methods: We retrospectively studied 123 patients with GD treated with RAI between 2004 and 2014 at Chonnam National University Hwasun Hospital. The responder group was defined as patients who developed hypothyroidism requiring levothyroxine replacement following RAI, regardless of the RAI dosage. Results: A total of 54 patients (43.9%) became hypothyroid after the first dose, and 31 needed two to four additional doses to achieve hypothyroidism. In the responder group as a whole (85 patients), the mean total dose of RAI was $15.5{\pm}7.0mCi$ and the mean thyroid volume (TV) was $35.4{\pm}23.4mL$. When divided into low dose (<15 mCi, n=46) and high dose (${\geq}15mCi$, n=39) responder groups, TV was significantly lower in the low-dose responder group ($25.7{\pm}11.4$ vs. $48.4{\pm}31.3$, p<0.001). The optimal cut-off TV for the low-dose responder group was <32.37 mL (sensitivity 80.9%, specificity 76.7%). Conclusion: TV had significant effects on the outcome of RAI in GD patients. The optimal fixed RAI dose for Korean GD patients with a large goiter (${\geq}33mL$) should be at least 15 mCi to achieve the best outcome.

電算流體力學의 發達過程과 展望

  • Graves, Randolph A.
    • Journal of the KSME
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    • v.22 no.4
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    • pp.262-270
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    • 1982
  • 머지않은 장래에는 이러한 초컴퓨터와 신기술들이 유체역학의 주요한 발전을 주도하고, 오랫동안 취급하지 못하였던 난류유통도 해석할 수 있을 것이며, 복잡한 비행기 형상의 외부 유통도 발 전된 형체막형화 기법과 격자발생법 및 그래픽 기술을 이용하여 손쉽게 계산될 것이다. 금세기 말까지의 공기역학의 발전은 주로 공기의 탄성효과를 고려한 비정상압축성 공기역학에서 이루 어질 것이다.

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