• 한국초지조사료학회지
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• 제43권2호
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• pp.109-115
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• 2023

Ammonium (NH₄⁺) serves as a nitrogen source, but its elevated levels can hinder plant growth and production. Excess NH₄⁺ with α-ketoglutarate is assimilated into glutamate, a precursor of proline and glutathione (GSH). This study aimed to investigate the effects of excessive NH₄⁺ on the regulation of proline and GSH synthesis. Detached leaves from oilseed rape (Brassica napus L.) were fed with 0, 50, 100, 500, and 1000 mM NH₄Cl for 16 h. As the NH₄⁺ concentrations increased, the leaves exhibited progressive wilting and yellowing. Furthermore, total carotenoid and chlorophyll concentrations declined in response to all NH₄⁺ treatments, with the lowest levels observed in 1000 mM NH₄⁺ treatment. Hydrogen peroxide (H₂O₂) concentration showed a minor increase at low NH₄⁺ concentration (50 and 100 mM) treatments but a significant increase at high NH₄⁺ (500 and 1000 mM), which was consistent with the localization of H₂O₂. Amino acid concentrations increased with increasing in NH₄⁺ concentration, while the protein concentration displayed the opposite trend. Proline and cysteine concentrations exhibited a gradual increase in response to increasing NH₄⁺ concentrations. However, GSH concentrations rose only in the 50 mM NH₄⁺ treatment and decreased in the 500 and 1000 mM NH₄⁺ treatments. These results indicate that excessive NH₄⁺ is primarily assimilated into proline, while GSH synthesis is adversely affected.

• 한국지리정보학회지
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• 제17권2호
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• pp.82-94
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• 2014

본 연구에서는 미얀마 내 Mandalay, Magway 지역에 대해 Landsat 4-5 TM 위성영상을 이용하여 토지피복 변화와 식생온도조건지수(Vegetation Temperature Condition Index; VTCI)의 관계를 분석함으로써, 미얀마 토지피복 변화와 건조 정도의 관계를 밝히고자 하였다. 토지피복 변화를 분석한 결과, 연구 대상 지역에서 산림은 감소하는 것으로 나타난 반면, 주거지와 농경지의 면적은 증가하였다. VTCI 분석을 수행한 결과, (a)지역에서는 매우 건조한 지역의 면적이 점차 감소하고, 건조한 지역 및 보통, 습윤한 지역의 면적이 증가하여 건조의 정도가 다소 감소되는 것으로 나타났다. (b)지역 또한 매우 건조한 지역의 면적이 증가하여 건조 정도가 심각해지는 것을 파악할 수 있었다. VTCI와 토지피복 변화의 관계 분석결과는 두 지역의 매우 건조한 지역에서 산림 및 주거지의 농경지로의 변화 비율이 비교적 높게 나타나고, 변화된 지역의 VTCI 평균이 감소하여 토지피복의 변화와 건조 정도의 변화의 관련성을 찾을 수 있었으며, 건조지역이 점차 증가하고 있음을 확인하였다.

• 생물정신의학
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• 제4권2호
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• pp.198-210
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• 1997

To examine the double-faced thymoleptic(antidepressant and antimanic) effects of risperidone in mood disorders, this article reviews the psychotropic-induced mania, thymoleptic effects of antipsychotics, therapeutic effects of risperidone and risperidone(RIS)-induced mania(RIM) in mood disorders, risk factors of RIM, possible neurochemical mechanism of these thymoleptic effects, pathophysiological and clinical significance of thymoleptic effects, and suggestive clinical guideline of RIS in mood disorders. RIS appeared effective for bipolar disorder at a lower dose than that recommended for schizophrenia, especially in the cases of maintenance of mood stabilizers, and gradual titration from low doses. Manic induction/exacerbation can occur by chance during RIS treatment in mood disorders, schizoaffective disorders, and schizophrenias. The possible risk factors for RIM are refractory mood disorder, especially in bipolar I disorder with poor initial response ; refractory schizoaffective disorders, especially in bipolar type with poor initial response ; refractory chronic schizophrenias, especially with initial responses ; psychotic features ; higher initial doses ; rapid titration ; combined therapy with antidepressants in refractory depression ; and RIS monotherapy in mania/hypomania. RIS is a drug that preferentially block 5-HT2 receptors. The effects of low dose are due mainly to the blockade of 5-HT2 receptors. There are more gradual increase in D2 blockade with increasing dose and this D2 blocking properties become apparent at higher doses. This may be related to a modulation of dopaminergic transmission by 5-HT2 antagonism at lower doses with the direct action of RIS on DA receptors coming into play at higher dose. The serotonergic antagonistic effect may be important for its effects on depressive symptoms. This, together with adequate blo-ckade of D2 receptors, may not necessarily lead to destabilization of mood disorder, but rather to more therapeutic effects. Therefore, this dose-receptor affinity relationship with both antidepressant and antimanic effects according to treatment duration can explain a continuum of antidepressant effect, antimanic effect, behavioral stimulation, and manic/hypomanic induction/exacerbation. It was the recognition of a useful psychiatric side effects by a thoughtful observer with fertile minds that led to their ultimate utilization as psychotropic drugs, i.e., phenothiazine, MAOI, TCA, and lithium. And, in vivo pharmacological challenge by novel psychotropics, as a neurochemical probe, with more specific actions is a useful tool to select pharmacologically homogeneous subgroup of the same phenotypical(clinical) condition, to further study the unknown underlying pathogenesis of various mental illnesses. Finally, RIS may be a useful alternative or adjunctive drug for patients with mood disorders without psychotic features or refractory to treatment with standard antipsychotic drugs. The more conservative doses(tirated slowly from 1-3 mg/d) of RIS, and maintenance of mood stabilizer in the cases with risk factors of RIM are recommended in mood disorder.

• Journal of Chest Surgery
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• 제29권1호
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• pp.1-6
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• 1996

5마리의 잡견(18~22kg)을 이용하여, 경막외강에 생리식염수를 연속 점적하여 뇌사를 유발시킨다. 뇌사발생시 점의 뇌압은 122.0$\pm$6.25mmHg이며 뇌사후 30분 최고치에 도달하였다. 뇌사를 유발시키는데 필요한 생리식염수의 양은 4.8$\pm$1.0ml이었고, 143.0$\pm$30.9분이 필요하였다. 뇌사가 올때까지 동맥압은 변하지 않지만 그후 점차 떨어지고, 맥박수는 뇌사 30분 후 안정시 보다 50% 정도 증가한 최고치에 달한다. 체온, 심박출량, 폐동맥압, 좌심실 이완말기압등의 혈역학적 지표는 뇌사진행 중에는큰 변화가 없었고, 심실 기외수축이 일시적으로 나타난 이외에는 부정맥도 관찰되지 않았다. 급작스러운 뇌압 상승 모델에서 보였던 혈역학적 변화는 관찰되지 않았다.

• 대한환경공학회지
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• 제36권6호
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• pp.412-420
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• 2014

중랑천 상류에서 하류 방향으로 4개 지점을 선정하여 3회의 강우 사상에 대하여 수질변화 특성을 조사하였다. 강우시 $COD_{Mn}$, SS와 $BOD_5$ 농도는 증가하고, T-N은 감소하고, T-P는 경향성이 뚜렷하게 나타나지는 않았으며, 경향성은 강우량과 강우강도 증가에 따라 더욱 뚜렷하게 나타났다. 누적 강우량과 수질항목별 단순회귀 분석 결과, T-N을 제외하고 전체적으로 양의 상관성을 갖는 것으로 나타나서 T-N은 누적강우량이 커질수록 농도가 감소하는 것으로 나타났고, 다른 항목들은 농도가 증가하는 것으로 나타났다. 시간당 평균 강우강도와 수질항목별 단순회귀분석 결과, $R^2$값이 전체적으로 약 0.483~0.992 범위의 대체적으로 폭 넓은 결정계수를 나타났으며, 강우강도가 강할수록, T-P와 T-N은 상류 유입, $COD_{Mn}$은 중류 및 하류 유입, SS는 상류에서 하류 방향으로의 점진적 증가 유입, 그리고 $BOD_5$는 상류에서 하류 방향으로의 점진적 감소 유입이 되는 것으로 판단되었다. 유량과 수질항목별 단순회귀 분석을 실시한 결과, 중랑천 상류가 유량의 증가와 함께 수질오염도가 민감하게 반응하는 것으로 나타났다.

• Journal of Animal Science and Technology
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• 제57권5호
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• pp.17.1-17.6
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• 2015

The present study investigated the nutritional and economic suitability of cashew reject meal (full fat and defatted) as replacement for groundnut cake (GNC) in the diets of laying chickens. A total of eighty four brown shavers at 25 weeks of age were randomly allotted into seven dietary treatments each containing 6 replicates of 2 birds each. The seven diets prepared included diet 1, a control with GNC at $220gkg^{-1}$ as main protein source in the diet. Diets 2, 3 and 4 consist of gradual replacement of GNC with defatted cashew reject meal (DCRM) at 50%, 75% and 100% on weight for weight basis respectively while diets 5, 6 and 7 consist of gradual inclusion of full fat cashew reject meal (FCRM) to replace 25%, 35% and 50% of GNC protein respectively. Each group was allotted a diet in a completely randomized design in a study that lasted eight weeks during which records of the chemical constituent of the test ingredients, performance characteristics, egg quality traits and economic indicators were measured. Results showed that the crude protein were 22.10 and 35.4% for FCRM and DCRM respectively. Gross energy of DCRM was 5035 kcal/kg compared to GNC, 4752 kcal/kg. Result of aflatoxin $B_1$ revealed moderate level between 10 and $17{\mu}g/Kg$ in DCRM and GNC samples respectively. Birds on control gained 10 g, while those on DCRM and FCRM gained about 35 g and 120 g respectively. Feed intake declined (P < 0.05) with increased level of FCRM. Hen day production was highest in birds fed DCRM, followed by control and lowest value (P < 0.05) was recorded for FCRM. No significant change (P > 0.05) was observed for egg weight and shell thickness. Fat deposition and cholesterol content increased (P > 0.05) with increasing level of FCRM. The cost of feed per kilogram decreased gradually with increased inclusion level of CRM. The prediction equation showed the relative worth of DCRM compared to GNC was 92.3% whereas the actual market price of GNC triples that of DCRM. It was recommended that GNC could be completely replaced by DCRM in layer's diets in regions where this by product is abundant. However, FCRM should be cautiously used in diets of laying chickens.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.73-73
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• 2017

To set an optimal harvest time of main 7 whole crop silage rice cultivars, Nokyang(Ny), Mogwoo(Mw), Mogyang(My), Jungmo1029(Jm1029), Jungmo1038(Jm1038), Nokwoo(Nw) and Yeongwoo(Yw), based on feed value, we analyzed their feed values such as percent crude protein(CP), crude fat(CF), crude ash(CA), neutral detergent fiber(NDF), acid detergent fiber(ADF) and lignin. It was evaluated every 10 days from heading to 40 days after heading(DAH). Total digestible nutrient(TDN) and relative feed value(RFV) was also calculated from ADF and NDF. As results, CP was generally in decline as increasing DAH in Ny, My, Jm1029, Jm1038 and Yw and decreased to 20 DAH in Mw, decreased after increasing to 30 days in Nw. The CP content of Ny was relatively the highest ranged from 5.3% to 10.1% and Mw the lowest 4.5% to 5.2%, compared to others. CF content tend to decrease as DAH increase in Ny, My and Nw and decreased after increasing to 30 days Jm1029, increased after decreasing to 20 days Jm1038 but was not shown distinct trend of increase or decrease in Mw. Especially, that of Yw's CF gradually increased as harvest time late but relative content the lowest from 1.46% to 2.29% among 7 cultivars. The CA content of Ny, My, Jm1029 and Jm1038 approximately decreased as DAH increased and that of Mw was similar to others after heading, Nw decreased after 10 days and Yw increased after flowering. In all 7 cultivars, NDF and ADF had a tendency to decrease as days accumulated, in particular, Yw was the lowest on 30 DAH and so the content of Yw's TDN the highest(71.5%), while the lowest(67.2%) in Nw. For lignin, particularly, Mw tend to be in decline as DAH increase and was the lowest ranged from 1.34% to 1.87%. ADF analyses allows for the evaluation of in vivo digestible dry matter(DDM) and energy availability and NDF analyses provides the best indication of dry matter intake(DMI). Ultimately, the two factors can be combined to derive RFV for forage. RFV in general increased as DAH increased in all cultivars and was in order, Yw>My>Ny> Jm1038>Mw>Jm1029>Nw on 30 DAH. Taken together when these results, despite a slight increase of TDN after 30 DAH except Yw, considering forage yield potential, digestibility of grains and gradual decrease of CP and CF, the yellow ripe stage, about 30 DAH, was appropriate to harvest whole crop rice for silage use.

• 환경위생공학
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• 제7권2호
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• pp.1-10
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• 1992

Since 1960's along with industrialization and urbanization, economic growth has been . achieved, however, at the same time, environmental condition has been seriously deteriorated. . Currently, volume of wastewater has been increasing at annual rate of 7% in sewage and 20% in industrial wastewater. However, the nation's sewage treatment serves only 33% of the municipal wastewater as of 1991. Major portion of air pollutants comes from combustion of oil and coal which comprise 81% of total energy use and emission gases from motor vehicles increasing at an accelerated rate. It is known that Korea generates the highest amount of waste per capta. Nevertheless, it is not sufficient to reduce the volume of waste by means of resources recovery and recycling. Recognizing the importance of global environmental problems such as ozone layer depletion, global warming and acid rain, international society has been making various efforts since the 1972 Stockholm conference. In particular, it is expected that the Rio conference which has adopted the Rio declaration and Agenda 21 will form a crucial turning point of the emerging new world order after the Cold War confrontation. To cope with such issues as domestic pollution and global environmental problems, the fundamental national policy aims at harmonizing "environmental protection and sustainable development". The Ministry of Environment has recently set up a mid-term comprehensive plan which includes annual targets for environmental protection. According to the government plan, gradual improvement of various environmental conditions and specific measures to achieve them is planned in time frame. Additional sewage treatment plants will be constructed in urban areas with the target to treat 65% of the nation's municipal sewage by 1996. Supply of clean fuels such as LNG will also be expanded starting from large cities as a cleaner substitute energy for coal and oil. In parallel with expansion of LNG, emphasis will be placed on installation of stack monitoring system. Due to the relatively limited land, government's basic policy for solid waste treatment is to develop large scale landfill facilities rather than small sized ones. Thirty three regional areas have been designated for the purpose of waste management. For each of these regions, big scale landfill site is going to be developed. To increase the rate of waste recycling the government is planning to reinforce separate collection system and to provide industries with economic incentives. As a part of meeting the changing situation on global environmental problems after UNCED, and accommodation regulatory measures stipulated in the global environmental conventions and protocols, national policy will try to alter industrial and economic structure so as to mitigate the increasing trends of energy consumption, by encouraging energy conservation and efficiency. In this regard, more attention will be given to the policy on the development of the cleaner technology. Ultimately, these policies and programs will contribute greatly to improving the current state of national public health.

• Asian-Australasian Journal of Animal Sciences
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• 제31권12호
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• pp.1930-1938
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• 2018

Objective: The present study attempted to determine safe and sufficient growth promoters in poultry feeding. Methods: A total of 520 seven-day-old quail chicks were randomly allotted to eight treatment groups in a $4{\times}2$ factorial design experiment to evaluate the effect of different levels of humic acid (HA) and black cumin (BC) seed and their interactions on growth, carcass traits, gut microbes, and blood chemistry of growing quails. Quails were randomly distributed into 8 groups in a $4{\times}2$ factorial design, included 4 HA levels (0, 0.75, 1.5, and 2.25 g/kg diet) and 2 BC levels (0 or 5 g/ kg diet). Results: Increasing HA level associated with a gradual increase in final weight, feed intake and body weight gain along with an improvement in feed conversion ratio. Dietary addition of 5 g BC powder/kg diet gave similar results. The highest level of HA (2.25 g/kg diet) recorded the best values of carcass weight, breast yield, intestinal length, and intestinal weight comparing with the control and other HA levels. Total viable microbial counts decreased (p<0.05) with increasing levels of HA except the intermediate level (1.5 g/kg diet). The concentration of serum cholesterol and low density lipoprotein (excluding that 0.75 g HA) decreased (p<0.05) and high density lipoprotein increased (p = 0.034) along with increasing HA level. The interaction between the $2.25g\;HA{\times}5g$ gave the best results regarding most studied parameters. Conclusion: These findings indicated that HA combined with BC could be used as effective growth promoters, with the recommended level being 2.25 g HA+5 g BC/kg of quail diet.

• 대한치과교정학회지
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• 제26권3호
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• pp.225-239
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• 1996

본 연구는 한국인 남.녀 6세에서 17세 사이의 악안면 성장과 발육에 관한 준종단적 연구의 일부로 시행되었으며 3년간에 걸쳐 남.녀 아동 736명을 대상으로 치열궁의 성장변화를 관찰하고자 치아의 근원심 폭경, 견치간 폭경, 구치간 폭경, 견치 치열궁 장경, 구치 치열궁 장경 그리고 치열궁 주위경을 측정하여 연령별, 성별 평균과 표준편차를 구하고 도표로 표시하여 다음과 같은 결론을 얻었다. 결론 1. 치아의 근원심 폭경 측정에서 상악은 중절치, 제2대구치, 하악은 견치, 제2대구치에서 남.녀 성차이를 인정 할 수 있었다. 2. 견치간 폭경은 11세까지 완만히 증가하는 양상을 보였다. 3. 구치간 폭경은 상악에서는 지속적으로 증가하는 양상을 보이며 그 양상은 9세에서 14세사이에서 가장 두드러지게 나타났다. 하악에서는 9세까지는 다양한 변화를 보이며 이후 14세까지 다소 증가하는 경향을 보였다. 4. 견치 치열궁 장경은 상악에서는 13세까지, 하악에서는 11세까지 증가하는 양상을 보였다. 5. 구치 치열궁 장경은 남자에서는 10세, 여자에서는 9세까지 증가하는 경향을 보이며, 이러한 변화는 상악에서 더 뚜렸하게 나타났다. 이후 상하악 모두에서 감소하는 경향을 보이며 이는 상악에서는 15세, 하악에서는 12세 사이에서 두드러졌다, 6. 치열궁 주위경은 상.하악 모두 10세까지 증가하는 경향을 보이며 그 양상은 상악에서 더 크게 나타났다. 반면에 10세와 14세 사이에서는 감소하는 경향을 보이며 그 양상은 하악에서 더 크게 나타났다.