• Title/Summary/Keyword: good manufacturing practice

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The Seasonal Microbiological Quality Assessment for Application of HACCP System to the Elementary School Food Service (초등학교 급식소에서의 HACCP 적용을 위한 계절별 환경미생물학적 위해분석)

  • 권성희;이헌옥;정덕화;신원선;엄애선
    • Korean journal of food and cookery science
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    • v.19 no.5
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    • pp.647-658
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    • 2003
  • Foodservice at elementary schools has been provided nation-wide. It is predictable that foodborne diseases would increase continuously. Formation of a counterplan is urgently needed. This study was designed to identify the stage which contains the critical control points (CCPs) for the microbiological management of HACCP (Hazard Analysis Critical Control Point) at the foodservice provided at elementary schools. Foodservice places at four elementary schools in Seoul were sampled and the overall hygiene of cooking, utensils and equipment, employees, and environment by season were examined. The results showed that the number of bacteria in overall samples was increased and that E. coli, Salmonella and Staphylococcus by biochemical test emerged in more diverse samples in summer than in spring. Particularly, the number of aerial bacteria in summer was three-fold greater than that in either spring or winter. E. coli 0157 was not detected, although Salmonella was identified by PCR analysis in the meat knives, chopping boards, waste bins and meat dish at elementary school foodservice. According to this data, cross-contamination should be managed in the stage of mixing up the ingredients with improper equipments and insanitary treatments. Thus, the establishment of SSOP (Sanitation Standard Operating Procedures) and GMP (Good Manufacturing Practice) at elementary school foodservice is stringently required, along with sanitation education for workers and employees as CCPs.

Numerical comparison between lattice and honeycomb core by using detailed FEM modelling

  • Giuseppe, Pavano
    • Advances in aircraft and spacecraft science
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    • v.9 no.5
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    • pp.377-400
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    • 2022
  • The aim of this work is a numerical comparison (FEM) between lattice pyramidal-core panel and honeycomb core panel for different core thicknesses. By evaluating the mid-span deflection, the shear rigidity and the shear modulus for both core types and different core thicknesses, it is possible to define which core type has got the best mechanical behaviour for each thickness and the evolution of that behaviour as far as the thickness increases. Since a specific base geometry has been used for the lattice pyramidal core, the comparison gives us the opportunity to investigate the unit cell strut angle giving the higher mechanical properties. The presented work considers a detailed FEM modelling of a standard 3-point bending test (ASTM C393/C393M Standard Practice). Detailed FEM modelling addresses to detailed discretization of cores by means of beam elements for lattice core and shell elements for honeycomb core. Facings, instead, have been modelled by using shell elements for both sandwich panels. On lattice core structure, elements of core and facings are directly connected, to better simulate the additive manufacturing process. Otherwise, an MPC-based constraint between facings and core has been used for honeycomb core structure. Both sandwich panels are entirely built of Aluminium alloy. Prior to compare the two models, the FEM sandwich panel model with lattice pyramidal core needs to be validated with 3-point bending test experimental results, in order to ensure a good reliability of the FEM approach and of the comparison. Furthermore, the analytical validation has been performed according to Allen's theory. The FEM analysis is linear static with an increasing midspan load ranging from 50N up to 500N.

A Study on the Development of Tube-to-Support Nonlinear Impact Analysis Model (튜브와 지지대 사이의 비선형 충격해설모델 개발에 관한 연구)

  • 김일곤;박진무
    • Journal of KSNVE
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    • v.5 no.4
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    • pp.515-524
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    • 1995
  • Tubes in heat exchanger of fuel rods in reactor core are supported at intemediate point by support p0lates or springs. Current practice is, in case of heat exchanger, to allow clearance between tube and support plate for design and manufacturing consideration. And in case of fuel rod the clearance in support point can be generated due to the support spring force relaxation. Flow-induced vibration of a tube can cause it to impact or rub against support plate or against adjacent tubes and can result in fretting-wear. The tube-to- support dynamic interaction is used to relate experimental wear data from single-span test rigs to real multi-span heat exchanger configurations. The dynamic interaction cna be measured during experimental wear tests. However, the dynamic interaction is difficult to measure in real heat exchangers and, therefore, analytical techniques are required to estimate this interaction. This paper describels the nonlinear impact model of DAGS(Dynamic Analysis of Gapped Structure) code which simulates the tube response to external sinusodial or step excitation and predicts tube motion and tube-to-support dynamic interaction. Three experimental measurements-two single span rods excited by sinusodial force and a two span rod impacted by a steel ball are compared from the simulation nonlinear model of DAGS code. The simulation results from DAGS code are in good agreement with measurements. Therefore, the developed model of DAGS code is good analytical tool for estimating tube-to-support dynamic interaction in real heat exchangers.

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Characterizing a Full Spectrum of Physico-Chemical Properties of Ginsenosides Rb1 and Rg1 to Be Proposed as Standard Reference Materials

  • Kim, Il-Woung;Hong, Hee-Do;Choi, Sang-Yoon;Hwang, Da-Hye;Her, Youl;Kim, Si-Kwan
    • Journal of Ginseng Research
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    • v.35 no.4
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    • pp.487-496
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    • 2011
  • Good manufacturing practice (GMP)-based quality control is an integral component of the common technical document, a formal documentation process for applying a marketing authorization holder to those countries where ginseng is classified as a medicine. In addition, authentication of the physico-chemical properties of ginsenoside reference materials, and qualitative and quantitative batch analytical data based on validated analytical procedures are prerequisites for certifying GMP. Therefore, the aim of this study was to propose an authentication process for isolated ginsenosides $Rb_1$ and $Rg_1$ as reference materials (RM) and for these compounds to be designated as RMs for ginseng preparations throughout the world. Ginsenoside $Rb_1$ and $Rg_1$ were isolated by Diaion HP-20 adsorption chromatography, silica gel flash chromatography, recrystallization, and preparative HPLC. HPLC fractions corresponding to those two ginsenosides were recrystallized in appropriate solvents for the analysis of physico-chemical properties. Documentation of the isolated ginsenosides was made according to the method proposed by Gaedcke and Steinhoff. The ginsenosides were subjected to analyses of their general characteristics, identification, purity, content quantitation, and mass balance tests. The isolated ginsenosides were proven to be a single compound when analyzed by three different HPLC systems. Also, the water content was found to be 0.940% for $Rb_1$ and 0.485% for $Rg_1$, meaning that the net mass balance for ginsenoside $Rb_1$ and $Rg_1$ were 99.060% and 99.515%, respectively. From these results, we could assess and propose a full spectrum of physicochemical properties for the ginsenosides $Rb_1$ and $Rg_1$ as standard reference materials for GMP-based quality control.

Microbiological Evaluation for HACCP Implementation of Wholesale Bakery Products (제빵업체의 HACCP 모델 적응을 위한 미생물학적 위해도 평가)

  • Kim Hye Young;Park Jae Young;Chung Duck Hwa;Oh Sangsuk
    • Journal of Food Hygiene and Safety
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    • v.19 no.4
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    • pp.185-192
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    • 2004
  • Generic HACCP models for bakery products may help HACCP implementation at the wholesale bakery production lines easier. When baking, the internal temperature of bakery products went up to $85^{\circ}C$, which resulted in gelatinization of starch. Considering the characteristics of bakery products, general sanitation control procedures are the main target tool to keep bakery products safe. Monitoring of pathogenic microorganisms at bakery plant environment including production lines was carried out. At the wholesale bakery environment pathogenic microorganisms were detected. It gave a clue that general sanitation control procedures should be implemented for safe bakery products supply. Hazard analysis of raw materials and processing of bakery products, and determination of critical control points and critical limits at the wholesale bakeries lead to present generic model of bakery product HACCP plan. CCPs for the wholesale bakery products may be applied and modified for the implementation of HACCP plan at the wholesale bakery plant.

Prediction Model for Health Promotion Behaviors of the Workers in an Area (일 지역 근로자의 건강증진행위 예측모형)

  • Lee, Mee-Ja
    • Research in Community and Public Health Nursing
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    • v.15 no.1
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    • pp.102-109
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    • 2004
  • Purpose: The purpose of this study was to confirm a structural model for health promotion for industrial workers. Methods: Data was collected by questionnaires from 294 industrial workers at a food manufacturing factory. The data collected were analyzed through SAS 8.1 and Window LISREL 8.12a. Results: 1. The result of the test showed that the measurement of fitness was $x^2$=(삭제) 443.35, $x^2$/df 5.3415, GFI .86, AGFI .75, RMR .060, NFI .95, NNFI .93, CN 77.58, and those other than NFI and NNFI did not well fit into the practical data. 2. 15 out of 29 paths in a constructed model were statistically significant. 3. The measurements for total fitness in the modified model were $x^2$= (삭제) 146.51, $x^2$/df 1.8546, GFI .95, AGFI .91, RMR .042, NFI .98, NNFI .99, CN 223.44, all of which showed fitness in good shape to the practical data. 4. The result of the study for the modified model indicated that perceived self efficacy had the most significant direct effect on health promotion behaviors, and self esteem, perceived benefits of action, interpersonal influences, commitment to a plan of action were important factors having influences on them. Conclusion: The derived model in this study is considered appropriate in explaining and predicting health promoting behavior of industrial workers. Therefore, it can effectively be used as a reference model for further studies and suggested implication in nursing practice.

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Performance Characteristics of Thrust Measurement System for Hot-Firing Test of Small Liquid Propulsion Engines (소형 액체 추진기관 연소 시험을 위한 추력 측정 장치의 성능 특성 연구)

  • Kim, In-Tae;Huh, Hwan-Il;Kim, Jeong-Soo;Jang, Ki-Won;Lee, Jae-Won
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.32 no.9
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    • pp.122-129
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    • 2004
  • An accurate thrust measurement is one of the critical paths to the successful test and evaluation program of small liquid propulsion engines. This study describes the design factors for the development of thrust measurement system (TMS) as well as manufacturing practice of TMS hardware. We investigate characteristics of the TMS and its performance through hot-firing test of small liquid engine in a vacuum test cell which is capable of simulating 100,000 ft of altitude or higher. For performance test of TMS, we measure thrusts by changing propellant injection pressure at steady state firing mode as well as at pulse firing mode. Measured eigen frequency of the TMS is 67 Hz. Linearity test of the TMS shows good performance with less than 0.5% of linearity error.

Human Body Mechanics of Pushing and Pulling: Analyzing the Factors of Task-related Strain on the Musculoskeletal System

  • Argubi-Wollesen, Andreas;Wollesen, Bettina;Leitner, Martin;Mattes, Klaus
    • Safety and Health at Work
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    • v.8 no.1
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    • pp.11-18
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    • 2017
  • The purpose of this review is to name and describe the important factors of musculoskeletal strain originating from pushing and pulling tasks such as cart handling that are commonly found in industrial contexts. A literature database search was performed using the research platform Web of Science. For a study to be included in this review differences in measured or calculated strain had to be investigated with regard to: (1) cart weight/ load; (2) handle position and design; (3) exerted forces; (4) handling task (push and pull); or (5) task experience. Thirteen studies met the inclusion criteria and proved to be of adequate methodological quality by the standards of the Alberta Heritage Foundation for Medical Research. External load or cart weight proved to be the most influential factor of strain. The ideal handle positions ranged from hip to shoulder height and were dependent on the strain factor that was focused on as well as the handling task. Furthermore, task experience and subsequently handling technique were also key to reducing strain. Workplace settings that regularly involve pushing and pulling should be checked for potential improvements with regards to lower weight of the loaded handling device, handle design, and good practice guidelines to further reduce musculoskeletal disease prevalence.

Dental alloplastic bone substitutes currently available in Korea

  • Ku, Jeong-Kui;Hong, Inseok;Lee, Bu-Kyu;Yun, Pil-Young;Lee, Jeong Keun
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.45 no.2
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    • pp.51-67
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    • 2019
  • As dental implant surgery and bone grafts were widely operated in Korean dentist, many bone substitutes are commercially available, currently. For commercially used in Korea, all bone substitutes are firstly evaluated by the Ministry of Health and Welfare (MOHW) for safety and efficacy of the product. After being priced, classified, and registration by the Health Insurance Review and Assessment Service (HIRA), the post-application management is obligatory for the manufacturer (or representative importer) to receive a certificate of Good Manufacturing Practice by Ministry of Food and Drug Safety. Currently, bone substitutes are broadly classified into C group (bone union and fracture fixation), T group (human tissue), L group (general and dental material) and non-insurance material group in MOHW notification No. 2018-248. Among them, bone substitutes classified as dental materials (L7) are divided as xenograft and alloplastic bone graft. The purpose of this paper is to analyze alloplastic bone substitutes of 37 products in MOHW notification No. 2018-248 and to evaluate the reference level based on the ISI Web of Knowledge, PubMed, EMBASE (1980-2019), Cochrane Database, and Google Scholar using the criteria of registered or trademarked product name.

A Critical Discourse Analysis Through Comparisons Between Editorials of The Global Times, Huánqiú Shíbào on the 2018 United States-China Trade War (미·중 무역 분쟁 관련 환구시보(環球時報) 사설 비교를 통한 비판적 담화분석 - 「용타항미원조적의지타대미무역전(用打抗美援朝的意志打對美貿易戰)」 중심으로 -)

  • Choi, Tae-hoon
    • Cross-Cultural Studies
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    • v.52
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    • pp.165-194
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    • 2018
  • Employing Fairclough's critical discourse analysis (CDA), the purpose of this study was to analyze linguistically significant features, intertextuality, and sociocultural practice focusing on selected editorials of The Global Times, $Hu{\acute{a}}nqi{\acute{u}}$ Shíbào on the 2018 United States-China Trade War. The editorial titled "With the strong will of 'the War to Resist America and Aid Chosun,' let us go through the trade war against America" focused on the use of 'war' related vocabulary in the frame of 'war.' First, "Trade War" and "War to Resist America and Aid Chosun" are examples that reveal metaphors and a war frame. Second, "Strategy" is used positively for China but negatively towards America. Third, various war related words are used. Fourth, cases of allusion illustrate war. Intertextuality in terms of discourse practice pertains to two findings. First, The Global Times, $Hu{\acute{a}}nqi{\acute{u}}$ Shíbào repeatedly uses the phrase 'equivalent revenge.' That is because the expression enables China to justify their counterattack and such war that China may wage can be interpreted as just counterattack much like a self-defense mechanism. Second, the expression, 'the counterattack is not intended but it is not fearful' is repeated in several editorials of the newspaper. The reasons are the following: 1) it is used to appeal to the public, 2) by invoking the feeling of fear, the public should be understand why they should unite, and 3) the expression, "it is not fearful" is used to preserve China's global image and "the counterattack is not intended" is used to signal China's will to America. The whole expression is a good example of intertextuality that repetitively illustrates the intended meaning of China in nine editorials in the newspaper within three months, March 23-June 17, 2018. Finally, sociocultural practice is manipulated through the editorial for disseminating the Chinese government's hegemonic ideology. First, it is clear that the core national project, "China Manufacturing 2025" cannot be abandoned. Second, by calling for "War to Resist America and Aid Chosun" the editorial is manipulated to condemn and intimidate America, avoid dissent of the people, appeal to the people, and empower the government. Third, China somehow wants to open up the possibility of negotiation with the United Sates.