• Title/Summary/Keyword: glutathione S-transferase, glutathi one

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Taraxacum mongolieum Hand-Mass Aqua-acupuncture Solution as the Blocking Agent of Carcinogenesis (포공영약침액의 발암과정 blocking agent로서의 활성)

  • 손윤희;김소연;임종국;남경수
    • Journal of Life Science
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    • v.12 no.5
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    • pp.549-554
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    • 2002
  • Taraxacunf mongofieum Hand-Mass aqua-acupuncture solution (TMAS) was prepared and investigated og, the effect on initiation of carcinogenesis. The following effe.Is as a blocking agent were measured. .(a) Indu.ction of quinone reductase, (b) Induction of glutathione S-transferase activity (c) Increase of reduced glutathione. TMAS was potent inducer of quinone reductase in Hepa Iclc7 murine hepatoma cells. Clutathione S-transferase activity was increased with TMAS. In addition glutathione levels were increased about 1.6-fold with TMAS in cultured murine hepatoma Hepa Iclc7 cells.