• 학교보건
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• 통권26호
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• pp.31-34
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• 2006

사구체 질환들은 주로 면역학적 기전에 의해 일어나며 그밖에 대사장애, 혈역학, 독성, 침착, 감염, 유전성 등의 비 면역학적 기전으로도 일어난다.

• Journal of Yeungnam Medical Science
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• 제4권2호
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• pp.185-191
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• 1987

저자들은 임상소견, 혈액학적 소견, 면역학적 소견 및 신생검을 통해 낭창성 신염으로 진단된 2례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• 한국잠사학회:학술대회논문집
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• 한국잠사학회 2003년도 International Symposium of Silkworm/Insect Biotechnology and Annual Meeting of Korea Society of Sericultural Science
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• pp.145-146
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• 2003

Overproduction of transforming growth factor (TGF)-$\beta$l has been implicated in the pathogenesis of fibrotic diseases. TGF-$\beta$l plays a crucial role in the accumulation of extracellular matrix (ECM) in human and experimental glomerular diseases. However, it remains unclear whether inhibition of TGF- $\beta$l overproduction would suppress TGF- $\beta$l induced ECM accumulation. To inhibit the overproduction of TGF- $\beta$l in experimental glomerulonephritis induced by anti-Thy 1.1 antibody, we introduced antisense oligodeoxynucleotides (ODN) fur TGF- $\beta$l into the nephritic kidney by the HVJ-liposome-mediated gene transfer method. (omitted)

• 한국동물위생학회지
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• 제19권3호
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• pp.227-237
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• 1996

In order to investigate the prevalence and pattern of renal lesions in sows, 250 kidneys collected from abattoir were examined grossly and histopathologically. The prevalence of renal lesions in sows was 46.8% (l17/250). Main gross findings were consisted of congestion and/or petechiation (21.6%), cortical enlargement (15.2%), renal cysts (6.0%), abscessation (4.4%), and infarction (1.5%). Principle microscopic lesions were composed of interstitial nephritis (25.6% ), glomerulosclerosis (13.6%), glomerular thrombosis (3.6%), amyloidosis (2.0%) and glomerulosclerosis (2.0%) Sixty four kidneys with interstitial nephritis was classified by 46 chronic and 18 acute cases. Among 34 kidneys with glomerulonephritis, there were divided into 18 membranous type, 9 proliferative type and 7 membranoproliferative type. For these results, it was confirmed that sows raised in Kwangju and Chonnam areas had been affected by a variety of pathological renal lesions.

• 대한수의학회지
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• 제29권4호
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• pp.559-565
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• 1989

In order to investigate the renal pathology of spontaneously occurring renal lesions, basic macroscopic inspection was conducted to 3,850 pigs randomly collected from local slaughter houses, and a total of 355 pigs (9.2%) were detected with various gross pathological conditions. Renal morphologic patterns for gross lesions were classified histopathologically as 123(34.5%) congestion, 81(22.8%) acute interstitial nephritis, 52(14.7%) chronic interstitial nephritis, 49(13.8%) hemorrhage, 39(11.0%) renal cyst, 29(8.2%) chronic glomerulonephritis, 18(5.1%) acute glomeruonephritis, 14(3.9%) infarction, 11(3.1%) thrombosis, 5(1.4%) atrophy, 5(1.4%) pyelonephritis and 1(0.3%) lymphosarcoma.

• Childhood Kidney Diseases
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• 제26권2호
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• pp.91-96
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• 2022

The messenger RNA-based vaccine for the coronavirus disease 2019 (COVID-19) may induce glomerulonephritis, including immunoglobulin A nephropathy (IgAN). New-onset IgAN triggered by vaccination against COVID-19 has been reported rarely, especially in children. Herein, we report a pediatric case of newly diagnosed IgAN after administration of the Pfizer vaccine for COVID-19. A 12-year-old girl was referred to our hospital for evaluation of gross hematuria after inoculation with the second dose of Pfizer's COVID-19 vaccine; she had no adverse effects after the first dose. At the time of admission, she showed heavy proteinuria and persistent hematuria. Kidney biopsy revealed an IgAN, and she was treated with an oral steroid and an angiotensin-converting enzyme inhibitor. Four months after discharge, the proteinuria and hematuria resolved completely.

• Childhood Kidney Diseases
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• 제27권2호
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• pp.55-63
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• 2023

In 2021, a new chapter on the general management of glomerulonephritis (GN) was added to the Kidney Disease: Improving Global Outcomes (KDIGO). It emphasizes the importance of early general management of GN for improving long-term kidney outcomes and prognosis. The chapter introduces the management of glomerular diseases in 18 subchapters. Here, kidney biopsy for the diagnosis and evaluation of kidney function and the management of complications, such as hypertension, infection, and thrombosis, are presented. Moreover, the adverse effects of glucocorticoids and immunosuppressive therapy, which are commonly used drugs for glomerular disease, are mentioned, and a guideline for drug selection is presented. Each subtheme focused on items reflecting the interpretation of the "practice points" of the expert working group are introduced. In this review of the general treatment for GN in the KDIGO guidelines, excluding pregnancy and reproductive health, we focused on and compared various references pertaining to pediatric GN management.

• 대한치과의사협회지
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• 제9권11호
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• pp.665-671
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• 1971

• 대한소아신장학회:학술대회논문집
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• 대한소아신장학회 2007년도 춘계학술대회 및 제8회 연수강좌
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• pp.3-4
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• 2007

• Tuberculosis and Respiratory Diseases
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• 제67권4호
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• pp.345-350
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• 2009

Erdheim-Chester disease (ECD) is a proliferative non-Langerhans cell histiocytosis of multiple organs. This is a rare disease of unknown etiology with a high mortality. We present the case report of a 26-year-old man diagnosed with ECD. He was referred to our hospital with elevated levels of aminotransferases. Although the diagnosis was uncertain, the patient was lost to follow up at that time. One year later, the patient returned to the hospital with generalized edema. Although a specific bone lesion was not found, the patient was experiencing the following: glomerulonephritis, aplastic anemia, hepatitis, and lung involvement. A lung biopsy was performed: the immunohistochemical stain were positive for CD68 and negative for S-100 protein and CD1a. We diagnosed as the patient as havinf ECD. Approximately 50% of ECD cases present with extraskeletal involvement. ECD should be considered as part of the differential diagnosis when multiple organs are involved.