• Title/Summary/Keyword: global

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Antimicrobial Activities of LCB01-0183, a New Oxazolidinone (새로운 옥사졸리디논계 항균제 LCB01-0183의 항균 활성)

  • Lee, Hyun-Hee;Jung, Sung-Ji;Jeong, Ji-Woong;Cho, Young-Lag;Kim, Yong-Zu;Kwak, Jin-Hwan
    • YAKHAK HOEJI
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    • v.57 no.2
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    • pp.95-100
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    • 2013
  • This study was performed to analyze in vitro and in vivo activities of LCB01-0183, a new oxazolidinone, against clinical isolates of bacteria. In vitro antibacterial activity of LCB01-0183 was tested by the two fold agar dilution method. In vivo activity of LCB01-0183 was determined against systemic infections in mice. LCB01-0183 showed most potent activity among the test compounds against clinical isolates of Gram-positive bacteria. Furthermore, the protective activity of LCB01-0183 was very effective against systemic infections in mice by oral or subcutaneous administration. In time kill study, LCB01-0183 showed a bacteriostatic activity during 24 hours. LCB01-0183 had potent in vitro and in vivo activity against Gram-positive bacteria including drug-resistant strains.

A Review of the Quality Control of Global Ocean Temperature and Salinity Data (전지구 수온 및 염분 자료 품질 관리에 관한 논의)

  • Chang, You-Soon
    • Journal of the Korean earth science society
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    • v.33 no.6
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    • pp.554-566
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    • 2012
  • High-density temperature and salinity profiles from the successful international Argo project made it possible to reproduce the three-dimensional global ocean state in near-real time, which also increased much attention on the data analysis studies of global ocean. This paper reviewed several important issues on the recent data analysis studies such as systematic biases of XBT (eXpendable BathyThermograph) and Argo data, sea level budget discrepancy between steric height and satellite observed data, heat content change, and the current status of the development of objective analysis fields. This study also emphasized that it is required to carry out very cautious ocean data quality control and understand global-scale ocean variability prior to analyzing the regional-scale ocean climate change, particularly, in the East Asian marginal Seas.

Opportunities for Synergistic Collaboration between U.S. and Asia in Construction Business, Research, and Education

  • Liu, LiangY.
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2007.11a
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    • pp.3-8
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    • 2007
  • "The world is flat" as the popular author Thomas L. Friedman declares in his best belling book about the progress of business globalization in the $21^{st}$ century [3]. Construction projects and related businesses have been global since the 1800's, but it has never seen such rapid transformation in both scope and depth as in the past decade. Construction projects today often bring together international design talents, construction management firms, local and international labor forces, and global suppliers. On a visit to Dubai in the United Arab Emirates on the Persian Gulf, a person will experience the complexity of globalization of modern construction projects- with Arab owners, European engineering and design companies, American construction management teams, Korean general contractors, Jordanian subcontractors, and labor forces from Thailand, Indonesia, Turkey, and Sri Lanka. A count of material suppliers reveals over 60 countries involved, covering all continents. Indeed construction projects are getting more and more complex and competitive, as is the project execution. The trend toward globalization poses both challenges and opportunities to construction and engineering companies competing on a global scale. While global competition may be a threat to many companies, there are, however, many opportunities for synergistic collaborations that can create win-win scenarios for construction business, research, and education. This paper presents some of the opportunities between the U.S. and Asia in business integration, research collaboration on technologies, and educational development, which may mutually benefit countries on either side of the Pacific.

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Active GNSS Antenna Implemented with Two-Stage LNA on High Permittivity Substrate

  • Go, Jong-Gyu;Chung, Jae-Young
    • Journal of Electrical Engineering and Technology
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    • v.13 no.5
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    • pp.2004-2010
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    • 2018
  • We propose a small active antenna to receive Global Navigation Satellite System (GNSS) signals, i.e., Global Positioning System (GPS) L1 (1,575MHz) and Russian Global Navigation Satellite System (GLONASS) L1 (1,600 MHz) signals. A two-stage low-noise amplifier (LNA) with more than 27 dB gain is implemented in the bottom layer of a three-layer antenna package. In addition, a hybrid coupler is used to combine signals from pair of proximately coupled orthogonal feeds with $90^{\circ}$ phase difference to achieve the circular polarization (CP) characteristic. Three layers of high permittivity (${\varepsilon}_r=10$) substrates are stacked and effectively integrated to have a small dimension of $64mm{\times}64mm{\times}7.42mm$ (including both circuit and antenna). The reflection coefficient of the fabricated antenna at the target frequency is below -10 dB, the measured antenna gain is above 26 dBic and the measured noise figure is less than 1.4 dB.

An Investigation of the Extinction and Ignition Characteristics Using a Flame-Controlling Method (화염온도 제어법을 이용한 확산화염의 소화 및 점화특성 검토)

  • Oh, Chang-Bo;Lee, Eui-Ju;Hwang, Cheol-Hong
    • Journal of the Korean Society of Safety
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    • v.26 no.1
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    • pp.21-26
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    • 2011
  • Extinction and ignition characteristics of $CH_4$-air counterflow diffusion flame were numerically investigated using a Flame-Controlling Method(FCM). A skeletal reaction mechanism, which adopts 17 species and 58 reactions, was used in the simulation. The extinction and ignition conditions of the $CH_4$-air diffusion flames were investigated with varying the global strain rate. Upper and middle branches of S-curve for the peak temperature in the inverse of the global strain rate space were obtained with the FCM. The structures of diffusion flames in the upper and middle branches of S-curve were compared. It was found that the global strain rate was not correlated with the local strain rate well in the low global strain rate region. It is expected that the FCM is very useful to obtaining the extinction and ignition condition of diffusion flame, such as fires.

Improved Global Maximum Power Point Tracking Method Based on Voltage Interval for PV Array under Partially Shaded Conditions

  • Ding, Kun;Wang, Xiang;Zhai, Quan-Xin;Xu, Jun-Wei;Zhang, Jing-Wei;Liu, Hai-Hao
    • Journal of Power Electronics
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    • v.14 no.4
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    • pp.722-732
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    • 2014
  • The power-voltage (P-V) curve of photovoltaic (PV) arrays connected in parallel to bypass diodes would have several local maximum power points (LMPP) under partial shading conditions (PSC). Conventional maximum power point tracking (MPPT) methods fail to search for the global maximum power point (MPP) because the searched peak point may remain at the LMPP on the P-V curve under PSC. This study proposes an improved MPPT algorithm to ensure that PV arrays operate at global maximum power point (GMPP) under PSC. The proposed algorithm is based on a critical study and a series of observations of PV characteristics under PSC. Results show the regularity of voltage interval between LMPPs. The algorithm has the advantages of rapidly reaching GMPP, maintaining stability, and recovering GMPP quickly when the operating condition changes. Simulation and experimental results demonstrate the feasibility of the proposed algorithm.

Effect of Sedative Dose of Propofol on Neuronal Damage after Transient Forebrain Ischemia in Mongolian Gerbils

  • Lee, Seong-Ryong
    • The Korean Journal of Physiology and Pharmacology
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    • v.4 no.1
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    • pp.73-79
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    • 2000
  • This study investigated whether propofol, an intravenous, non-barbiturate anesthetic, could reduce brain damage following global forebrain ischemia. Transient global ischemia was induced in gerbils by occlusion of bilateral carotid arteries for 3 min. Propofol (50 mg/kg) was administered intraperitoneally 30 min before, immediately after, and at 1 h, 2 h, 6 h after occlusion. Thereafter, propofol was administered twice daily for three days. Treated animals were processed in parallel with ischemic animals receiving 10% intralipid as a vehicle or with sham-operated controls. In histologic findings, counts of viable neurons were made in the pyramidal cell layer of the hippocampal CA1 area 4 days after ischemia. The number of viable neurons in the pyramidal cell layer of CA1 area was similar in animals treated with a vehicle or a subanesthetic dose of propofol. In terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick end-labeling (TUNEL) assay, semiquantitative analysis of dark-brown neuronal cells was made in the hippocampal CA1 area. There was no significant difference in the degree of TUNEL staining in the hippocampal CA1 area between vehicle-treated and propofol-treated animals. These results show that subanesthetic dose of propofol does not reduce delayed neuronal cell death following transient global ischemia in Mongolian gerbils.

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Novel Compensation Method of Positioning Error for LBS (LBS를 위한 새로운 측위오차 보정 기법)

  • Park, Young Sik;Hwang, Yu Min;Kim, Jin Young
    • Journal of Satellite, Information and Communications
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    • v.8 no.2
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    • pp.62-67
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    • 2013
  • Recently, users have been receiving LBS(Local Based Service) which provides various services. The LBS uses positioning information from satellites with using GPS(Global Positioning System). However, due to satellite signal's characteristics which are reflection and refraction in urban areas, users get unexpected positioning information error, expecially if there are so many tall buildings in a small area. To solve this problem, this paper offers a post-processing algorithm. It is consisted of users' direction vectors and positioning information. The positioning information with error is designed to be put on the direction vector. Through a car driving test in urban areas, we've got 11.1m(43%) improved result and demonstrated the superiority of its algorithm.

Global Time Synchronization for Wireless Sensor Networks (무선 센서 네트워크를 위한 전역 시각 동기 기법)

  • Hwang, So-Young;Yu, Don-Hui;Joo, Jae-Heum;Won, Sung-Hyun
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2010.05a
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    • pp.84-86
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    • 2010
  • Time information and time synchronization are fundamental building blocks in wireless sensor networks since many sensor network applications need time information for object tracking, consistent state updates, duplicate detection and temporal order delivery. Various time synchronization protocols have been proposed for sensor networks because of the characteristics of sensor networks which have limited computing power and resources. However, none of these protocols have been designed with time representation scheme in mind. Global time format such as UTC TOD (Universal Time Coordinated, Time Of Day) is very useful in sensor network applications. In this paper we propose time keeping and synchronization method for global time presentation in wireless sensor networks.

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A Dynamically Segmented DCT Technique for Grid Artifact Suppression in X-ray Images (X-ray 영상에서 그리드 아티팩트 개선을 위한 동적 분할 기반 DCT 기법)

  • Lee, Jihyun;Park, Joonhyuk;Seo, Jisu;Kim, Hojoon
    • Annual Conference of KIPS
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    • 2018.10a
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    • pp.813-816
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    • 2018
  • X-ray 진단에서 그리드 하드웨어의 사용은 산란선에 의한 영상의 왜곡을 보정할 수 있는 장점이 있는 반면, 반복되는 라인 형태의 그리드 아티팩트를 발생시키는 부작용을 수반한다. 본 논문에서는 이러한 그리드 라인을 제거하는 방법론으로서 이산코사인변환(DCT: discrete cosine transform)을 사용 하는 기법을 제안한다. X-ray 영상에서 그리드 라인의 특성은 피사체의 형태와 영상의 영역에 따라 서로 다른 특성을 갖는다. 이에 본 연구에서는 동적으로 재구성되는 분할 구조를 기반으로 DCT 변환을 적용하고 개별 영역별로 필터전달함수를 최적화하는 방법을 채택하였다. 추출된 주파수 영역 데이터에 대하여 그리드 라인의 대역을 검출하는 알고리즘을 제안하였으며, 필터전달함수로 Kaiser윈도우와 Butterworth 필터를 조합한 형태의 밴드스톱필러(BSF: band stop filter)를 구현하였다. 또한 블로킹 현상을 개선하기 위하여 다중 영상으로부터 경계선 부분의 픽셀값을 결정하는 방법론을 제안하였다. 제안된 이론에 대하여 실제 영상을 사용한 실험결과로부터 그 타당성을 평가하였다.