• 대한치과의사협회지
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• 제55권2호
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• pp.180-188
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• 2017

Introduction : Inadequate oral health control is a major risk of oral diseases. Regular home-based care is essential to maintain good oral hygiene. In particular, mouthrinses can support conventional tooth brushing in reducing accumulation of oral plaque. Effect : Antimicrobial mouthrinses are used as part of daily oral care to reduce plaque and gingivitis. Mouthrinses contains fluoride could help remineralization of enamel and dentin. The most common molecules contained in mouthrinses are chlorhexidine, essential oils, cetyl pyridinium chloride, triclosan, hyaluronic acid. Currently, chlorhexidine is the most efficacious compound, with both antiplaque and antibacterial activities. Similar results are reported for essential oils and cetyl pyridinium chloride, although with a somewhat reduced efficacy. Considering the adverse effects of chlorhexidine and its time-related characteristics, this molecule may best be indicated for acute/short term use, while essential oils and cetyl pyridinium chloride may be appropriate for long-term, maintenance treatment. Conclusion and suggestion : Antimicrobial mouthrinses are safe and effective, and when used in conjunction with brushing and flossing, they are an important method of reducing plaque and gingivitis. To improve compliance, dental health care professionals should adapt oral health care recommendations to fit patients' specific needs.

• 한국치위생학회지
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• 제14권3호
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• pp.327-332
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• 2014

Objectives : The purpose of the study is to investigate the self awareness of oral health, dental calculus and gingivitis according to smoking in soldiers. Methods : A self-reported questionnaire was filled out by 601 soldiers in Jeonnam military unit from April 7 to 23, 2013. The screening for oral examination was performed in the soldiers. The data were analyzed for frequency analysis and chi-square test by using SPSS 21.0 program. Results : The self awareness of smoking on oral health accounted for 27.0% in good status in nonsmokers, 23.5% of the past smokers answered good, and 16.5% of the smokers answered good. Approximately, 68.7% had dental calculus(p<0.05). The smokers tended to have more gingivitis than the nonsmokers and the past smokers(p<0.05). Conclusions : Smokers had low level of self awareness of oral health than the nonsmokers and the past smokers.

• 한국임상수의학회지
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• 제28권1호
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• pp.159-162
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• 2011

Three cats with 2 weeks to 1 month history of drooling, halitosis, difficulty eating and pain on opening the mouth were presented to local animal hospitals. On physical examination, the gingiva was swollen, bright red and very painful with bilaterally symmetric pattern. Surgically excised abnormal gingival biopsy samples were requested for diagnosis. Histopathologically, gingival epithelium showed severe hyperplasia and ballooning degeneration. Moderate to severe infiltration of lymphocytes and plasma cells were presented in lamina propria. Immunohistochemically, inflammatory cells of the samples demonstrated major positive reactions for T lymphocytes. But some plasma cells also presented. According to polymerase chain reaction, tissues samples were negative for four kinds of feline viral pathogens. Based on the clinical, gross, histopathologic findings, these three cases were diagnosed as lymphoplasmacytic gingivitis in cats. In our best knowledge, this is the first case report in Korea.

• 대한소아치과학회지
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• 제24권4호
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• pp.743-750
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• 1997

Gingivitis is the most prevalent type of periodontal disease and the dental plaque is considered as a major contributory factor. As the poor oral hygiene is firmly related to the occurrence of periodontal disease, pediatric dentist should make every effort to promote the oral health and control the plaque effectively for the high risk patients, especially for those who are under orthodontic treatment. P.M.T.C.(Professional Mechanical Tooth Cleaning), introduced by Dr. P. Axelsson in 1969, is a very effective method of plaque removal and can be performed by specially trained personnel. Two pediatric orthodontic patients were treated by P.M.T.C. for the elimination of gingivitis and gingival swelling. Signi ficant improvements of gingival condition were achieved in both cases but additional preventive programs and home care along with professional office care seem to be necessary for the best result.

• 미생물학회지
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• 제54권1호
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• pp.71-73
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• 2018

최근 Fusobacterium nucleatum subsp. polymorphum는 average nucleotide identity 및 genome-to-genome distance 분석법에 의해 Fusobacterium polymorphum로 재분류 되었다. F. polymorphum 그람 음성이면서, 혐기성 및 가는 섬유 모양의 세균이다. F. polymorphum은 사람의 구강 내 정상세균총의 하나이고, 치주질환의 원인 인자이다. F. polymorphum KCOM 1001 (= ChDC F119) 균주가 사람 치은염 병소의 치은연하치면세균막에서 분리되었다. F. polymorphum KCOM 1001 균주 유전체 염기서열을 해독하여 보고한다.

• 한국보건간호학회지
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• 제14권2호
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• pp.191-202
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• 2000

This study was conducted for 39 patients who are recipients of allogeneic hemopoietic stem cell transplantation at BMT ward of St. Mary's hospital affiliated to Catholic University of Korea from April to September 1999. The subjects were devided into two groups; those who received both TEl and chemo therapy as conditioning regimen (TEl group). and those who used chemo agents as singular conditioning regimen (chemo group). The oral intake status of the two groups were compared through physical assessment and blood chemistry exam of the subjects, and factors influencing their nutritional change and oral intake were explored in each stage of the transplantation (six stages: admission, conditional stage, date of transplantation, one week after transplantation, two weeks after transplantation, and three weeks after transplantation). The prior aim of the study was to provide baseline data to minimize delayed treatment from nutritional deficiency of the subjects. The results were as follows: 1. TBI group was significantly decreased of oral calorie intake in two weeks after transplantation compared to admission and conditioning stage while that of chemo group was significantly decreased on the date of transplantation. 2. TBI group was significantly decreased of protein intake in two weeks after transplantation compared to admission and conditioning stage. In chemo group, protein intake was significantly decreased on the date of transplantation compared to admission. It was remarkable that TBI group showed lesser protein intake than chemo group. 3. Both group were significantly decreased of BMI in one week and three weeks after transplantation compared to admission. TBI group showed significantly higher BMI than chemo group. 4. Both group were significantly decreased of Triceps Skinfold Thickness (TST)on the date of transplantation compared to admission stage. 5. TBI group was significantly decreased of mid-arm muscle circumference (MAMC) in two weeks after transplantation compared to admission, conditioning, date of transplantation. 6. TBI group was significantly decreased of albumin level in two weeks after transplantation compared admission stage. In chemo group, it was significantly decreased on the date of transplantation compared to admission, three weeks after the transplantation. 7. TBI group was significantly decreased of transferrin level in two weeks after transplantation compared admission, conditioning, date of transplantation and one week after transplantation. In chemo group, it was decreased of transferrin level in 3 weeks after transplantation. 8. Oral intake of TEl group was impacted by vomiting before transplantation and gingivitis after transplantation. In chemo group, it was impacted by vomiting before transplantation and by two factors, gingivitis and nausea, after transplantation. The results showed oral calorie intake was not different between the two groups while protein intake was significantly lower in TBI group than chemo group. Oral intake was significantly impacted by vomiting before transplantation in both groups, but affected by oral gingivitis in TBI group and gingivitis and nausea in chemo group after transplantation. This findings present that standardized strategies to manage nutrition and gingivitis more effectively are desperately needed to enhance oral intake and protein intake of patients who receive TBI as conditioning regimen.

• Journal of Periodontal and Implant Science
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• 제31권2호
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• pp.401-420
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• 2001

A novel glucanhydrolase from a mutant of Lipomyces starkeyi(KSM 22)has been shown effective in hydrolysis of mutan, reduction of mutan formation by Streptococcus mutans and removal pre-formed sucrose-dependent adherent microbial film and Lipomyces starkeyi KSM 22 dextranase has been strongly bound to hydroxyapatitie. These in vitro properties of Lipomyces starkeyi KSM 22 dextranase are desirable for its application as a dental plaque control agent. This study was performed to determine oral hygiene benefits and safety of dextranase(Lipomyces starkeyi KSM 22 dextranase)-containing mouthwash in human experimental gingivitis. This 3-week clinical trial was placebo-controlled double-blind design evaluating 1U/ml dextranase mouthwash and 0.12% chlorhexidine mouthwash. A total 39 systemically healthy subjects, who had moderate levels of plaque and gingivitis were included. At baseline, 1, 2 and 3 weeks, subjects were scored for plaque(Silness and $L{\ddot{o}e$ plaque index and plaque severity index), gingivitis($L{\ddot{o}e$ and Silness gingival index), and at baseline and 3 weeks of experiment, subjects were scored for plaque(Turesky-Quingley-Hein's plaque index and plaque severity index), tooth stain(Area and severity index system by Lang et al). Additionally, oral mucosal examinations were performed and subjects questioned for adverse symptoms. Two weeks after pre-experiment examinations and a professional prophylaxis, the subjects provided with allocated mousewash and instructed to use 20-ml volumes for 30s twice dailywithout toothbrushing. All the groups showed significant increase in plaque accumulation since 1 week of experiment. During 3 weeks' period, the dextranase group showed the least increase in plaque accumulation of Silness and $L{\ddot{o}e$ plaque index, compared to the chlorhexidine and placebo groups, but chlorhexidine group showed the least increase inplaque accumulation of Turesky-Quingley-Hein's plaque index. As for gingival inflammation, all the groups showed significant increase during 3 weeks of experiment. The dextranase group also showed the least increase in gingival index score, compared to the chlorhexidine as well as the placebo groups. Whereas the tooth stain was increased significantly in the chlorhexidine group, compared to the baseline score and the placebo group since 3 weeks of mouthrinsing. It was significantly increased after 3 weeks in the dextranase group, still less severe than the chlorhexidine group. As for the oral side effect, the dextranase group showed less tongue accumulation, bad taste, compared to the chlorhexidine group. From these results, mouthrinsing with Lipomyces starkeyi KSM 22 dextranase was comparable to 0.12% chlorhexidine mouthwashin inhibition of plaque accumulation and gingival inflammation and local side effects were if anything less frequent and less intense than chlorhexidine, in human experimental gingivitis. All data had provided positive evidence for Lipomyces starkeyi KSM 22 dextranase as an antiplaque agent and suggested that further development of dextranase formulations for plaque control are warranted.

• 대한수의사회지
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• 제52권11호
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• pp.654-658
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• 2016

• Journal of Periodontal and Implant Science
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• 제6권1호
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• pp.21.1-21.1
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• 1976

• Journal of Periodontal and Implant Science
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• 제10권1호
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• pp.44-44
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• 1980