• Title/Summary/Keyword: giant cell tumor of bone

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Primary Tumors of the Chest Wall (원발성 흉벽종양)

  • 마중성;최병우;유회성
    • Journal of Chest Surgery
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    • v.7 no.1
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    • pp.61-66
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    • 1974
  • Primary tumors of the chest wall are rare than those of other portions of the body. Soft tissue tumors of the chest wall, though these are benign or malignant, should not be paid special attentions about their management than other soft tissue tumors of the body. Thoracic skeletal tumors, however, have some problems in the treatment because of defect in chest wall leading to herniation of lung and paradoxical movement of thoracic cage. The authors experienced 10 case of primary chest wall tumors at the department of thoracic and cardiovascular surgery, the national medical center, during last 15 years. Five of 10 cases were soft tissue tumors, and they were 2 case of lipoma and each one case of myxosarcoma and leiomyosarcoma. Among 5 bone tumors there no cases of sternal tumor, and their histopathological diagnosis were each one of fibrous dysplasia, giant cell tumor, osteochondroma, Ewing`s sarcoma and osteogenic sarcoma. Wide excision, though it was palliative one in certain case, was performed in 9 cases and only diagnostic incisional biopsy in one case, There were no postoperative deaths during admission to the hospital and all cases were missed during short term follow up after discharge from the hospital.

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Segmental Resection and Rotationplasty for Bone Tumors about the Knee (슬관절부위의 골종양에서 시행한 하지 분절 절제 및 회전 재접합술)

  • Hahn, Su-Bong;Woo, Dong-Sam
    • Archives of Reconstructive Microsurgery
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    • v.3 no.1
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    • pp.16-23
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    • 1994
  • A segmental resection and rotationplasty was performed in 23 patients with malignant and aggressive boning tumor of the distal femur or proximal tibia between February 1988 and September 1992 at the Severance Hospital. There were 13 male and 10 female patients. The yongest was 5 years old and the oldest was 37 years old. Mean age at operation was 22 years. Of the 23 cases 14 were osteosarcoma, 7 were giant cell tumor and 2 were synovial sarcoma. After an average observation period of 32.5months, there was no evidence of local recurrence but 6 distant metastasis developed. According to Shriner's rating scale, the functional result were excellent or good in all cases. All patient were convinced that they chosen the appropriate operative procedure and the ability to achieve high level of activity was considered as the main benefit.

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Brown Tumors Due to Parathyroid Carcinoma; $^{99m}Tc-MIBI$ Scan Findings (Case Report) (부갑상선 암종에 의해 발생한 갈색 종양: $^{99m}Tc-MIBI$ 스캔 소견 (증례 보고))

  • Kim, Su-Zy;Yoon, Soek-Nam;Kim, Byung-Soek;Chung, Yoon-Soek;Park, Chan-Hee
    • The Korean Journal of Nuclear Medicine
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    • v.31 no.3
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    • pp.395-398
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    • 1997
  • Whole body $^{99m}Tc-MIBI$ scan in conjunction with parathyroid scan is an effective method in detecting parathyroid lesions in patients with bone pain and possible bone lesions such as brown tumors.

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Early Result of Hydroxyapatite in Bone Defect after Operative Treatment of Benign Bone Tumor (양성 골종양의 수술적 치료 후 발생한 골결손에서 시행한 Hydroxyapatite의 조기 결과)

  • Chung, So-Hak;Kwon, Young-Ho;Park, Young-Gyun;Kim, Jae-Do
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.1
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    • pp.25-32
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    • 2008
  • Purpose: This study was performed to evaluate the efficiency of Hydroxyapatite ($Bongros^{(R)}$-HA) what use for bone defect after operative treatment of benign bone tumor. Materials and Methods: Hydroxyapatite, was used to treat bone defect after operative treatment of benign bone tumor from September, 2006 to December, 2007. A total of 17 benign bone tumor cases (10 males and 7 females) with mean age of 28.5 was observed studied. The diagnoses were fibrous dysplasia in 8 cases, solitary bone cyst in 5 cases, and giant cell tumor in 4 cases. In categorization by location of tumor, there were 6 cases of proximal femur, 3 cases of proximal femur, 3 cases of proximal tibia, 4 cases of proximal humerus, and 1 case of hip bone. Autogenous bone was used with Hydroxyapatite in 4 cases, and only Hydroxyapatite used in 13 cases. Periods of Follow-up were from 3 months to 15 months, and mean period were 7.5 months. Amount of graft resorption and bone formation was observed with compare of post operation radiograph and the difference was shown by percentage. Results: More than 98% bone uptake was observed after mean 4.5 months, and more than 98% bone formation was observed after mean 6.2 months. Lesser bone defect size showed faster bone formation and it was statistically significant result (P=0.012). But other comparative studies on other factors such as sex, age of patients and combination of autogenous bone were no statistically significant differences in graft resorption and bone formation. And there was no significant complications in periods of follow-up. Conclusion: Hydroxyapatite is considered as one of useful method of bone defect after operative treatment of benign bone tumor.

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Clear Cell Chondrosarcoma of the Scapula in a Child -A Case Report- (소아의 견갑골에 생긴 투명세포연골육종 - 1예 보고 -)

  • Lee, Kyung-Ji;Lee, An-Hi;Kim, Jean-A;Kim, Hyoung-Min;Lee, Kyo-Young
    • The Journal of the Korean bone and joint tumor society
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    • v.15 no.2
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    • pp.155-159
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    • 2009
  • Clear cell chondrosarcoma is a rare, low-grade variant of chondrosarcoma that comprises approximately 2% of all chondrosarcomas. This tumor usually involves the epiphysis and epimetaphysis of long bones, especially the proximal part of the femur or humerus, whereas involvement of the scapula is rare. It occurs at any age, but the peak is third to fifth decade, and is rarely seen in the first and second decades of life. Histologically, tumor cells with abundant clear cytoplasm and benign giant cells are usually found. We report on a case of clear cell chondrosarcoma of the scapula in an 8-year-old girl.

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Malignant Transformation of Giant Cell Tumor Not Associated with Radiotherapy (방사선 조사 없이 속발한 거대 세포종의 악성 전환)

  • Lee, Sang-Hoon;Oh, Joo-Han;Yoo, Kwang-Hyun;Suh, Sung-Wook;Ahn, Jun-Hwan;Kim, Han-Soo;Lim, Soo-Taek
    • The Journal of the Korean bone and joint tumor society
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    • v.8 no.1
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    • pp.12-19
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    • 2002
  • Purpose : Giant cell tumors(GCT) sometimes undergo malignant transformation after the radiotherapy, but very rarely do without radiotherapy. We reviewed the clinical experiences of the malignant transformation of GCT to suggest the guidelines for diagnosis and treatment of them. Materials and Methods : We examined four patients of pathologically proven malignant transformation of GCT, which occurred after the operative treatment alone without radiation, from September 1985 to January 2001. The mean follow-up period after the malignant transformation was 2.4 years(range, 1.3~4 years). Results : The mean time-interval from the initial diagnosis to the malignant transformation was 6.9 years(range, 2.2~13.5 years). The locations of tumors were soft tissues of proximal upper arm, proximal femur, distal femur and proximal tibia. The histology of malignant GCT was osteosarcoma in 3 cases and malignant fibrous histiocytoma in 1 case. Local recurrence developed in 1 patient and the pulmonary metastasis developed in 3 patients which transformed to osteosarcoma. Conclusion : Thorough sampling of the surgical specimen appears to be a very important factor for diagnosing the malignant transformation of GCT. In case of suspicion of malignancy in radiographs, the incisional biopsy should be followed by definite treatment rather than the improper resection.

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Proximal Humerus Brown Tumor with Primary Hyperparathyroidism in Pregnancy (임신중 발생한 원발성 부갑상선 기능 항진증을 동반한 상완골 근위부의 Brown tumor)

  • Jung, Sung-Taek;Kim, Hyun-Jeong;Lee, Dam-Seon;Park, Gi-Heon
    • The Journal of the Korean bone and joint tumor society
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    • v.13 no.2
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    • pp.173-179
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    • 2007
  • Brown tumor is tumor like lesion resulted from hyperparathyroidism, and it has been rarely reported recently. We evaluated a 29-year-old woman who had brown tumor on proximal humerus caused by primary hyperparathyroidism. She first had presented pain and swelling over the upper arm, and was suspected as giant cell tumor in biopsy combined with hyperparathyroidism. Wide marginal excision and tumor prosthesis were performed. However, it was confirmed as brown tumor resulted from parathyroid adenoma according to laboratory findings and radioactive isotopes image, and surgical excision of adenoma relieved clinical symptoms. We report this case with a review of literatures.

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Periosteal Ganglion of the Distal Fibula - A Case Report - (원위 비골에서 발생한 골막하 결절종 - 증례 보고 -)

  • Lee, Hyung-Seok;Kim, Jung-Ryul
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.2
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    • pp.178-181
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    • 2008
  • In contrast to ganglion of the soft tissue, periosteal ganglion occurring within or beneath the periosteum is a rare disorder. The differential diagnosis includes periosteal chondroma, lipoma, giant cell tumor of tendon sheath and periosteal osteosarcoma. Most common location for periosteal ganglion is the tibia, followed by radius, femur and ulna. To our knowledge, only 1 case of periosteal ganglion of the fibula has been reported in the literature. We report a case of periosteal ganglion of the distal fibula in a thirty-year-old woman treated with excision of the cyst and the adjacent periosteum.

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Malignant Transformation to Osteosarcoma from GCT (골육종으로 악성 전환된 거대 세포종 - 증례 보고 -)

  • Cho, Wan-Hyung;Lee, Seung-Jun;Cho, Sang-Hyeon;Lee, Soo-Yong
    • The Journal of the Korean bone and joint tumor society
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    • v.13 no.2
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    • pp.167-172
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    • 2007
  • Malignant transformation of giant cell tumor (GCT) is known to be rare. Most of malignant transformation is reported to occur after radiation and malignant transformation without prior radiation is extremly rare. Both radiographic and pathologic findings are confusing to make a correct diagnosis. Due to the poor prognosis, early aggressive treatment is mandatory. We report this rare case together with the review of the literature.

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Benign Tumors of the Talar Body (거골 체부에 발생한 양성 종양)

  • Suh, Sung-Wook;Lee, Sang-Hoon;Kim, Han-Soo
    • The Journal of the Korean bone and joint tumor society
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    • v.8 no.3
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    • pp.76-82
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    • 2002
  • Purpose: Benign bone tumor of the talar body have rarely been evaluated according to the therapeutic methods because of the scarcity of their incidence. Here, we report our experience of 8 cases who were treated by using of posterior approach and curettage through the posterior process of the talus. Materials and Methods: Between February 1986 and October 2001, we experienced 8 cases of benign bone tumor occurring in the talar body. They included two osteoid osteomas, two giant cell tumors, one capillary hemangioma, one chondroblastoma, one simple bone cyst, and one osteochondroma. Their mean age was 22.1 years (ranging from 10 to 41 years). Mean follow-up period was 7.7 years (ranging from 1 to 16 years). All patients were treated by using of posterior approach. Two osteoid osteomas and one osteochondroma were treated by excision of tumors. Other cases were treated with curettage through the cortical window on the posterior process of the talus. Results: There was no recurrence during the follow-up period. one infection occurred. Except this case, all patients had no pain in weight-bearing, and complete range of movement at the ankle joint was reserved in each case. Conclusion: In this study, we suppose that posterior approach to the talar body may be a safe method with minimal damage of normal tissues and sufficient of curettage is capable through the cortical window on the posterior process of the talus.

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