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Use of artificial intelligence in the management of T1 colorectal cancer: a new tool in the arsenal or is deep learning out of its depth?

  • James Weiquan Li;Lai Mun Wang;Katsuro Ichimasa;Kenneth Weicong Lin;James Chi-Yong Ngu;Tiing Leong Ang
    • Clinical Endoscopy
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    • 제57권1호
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    • pp.24-35
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    • 2024
  • The field of artificial intelligence is rapidly evolving, and there has been an interest in its use to predict the risk of lymph node metastasis in T1 colorectal cancer. Accurately predicting lymph node invasion may result in fewer patients undergoing unnecessary surgeries; conversely, inadequate assessments will result in suboptimal oncological outcomes. This narrative review aims to summarize the current literature on deep learning for predicting the probability of lymph node metastasis in T1 colorectal cancer, highlighting areas of potential application and barriers that may limit its generalizability and clinical utility.

The Effects of Bronchiectasis on Asthma Exacerbation

  • Kang, Hye Ran;Choi, Gyu-Sik;Park, Sun Jin;Song, Yoon Kyung;Kim, Jeong Min;Ha, Junghoon;Lee, Yung Hee;Lee, Byoung Hoon;Kim, Sang-Hoon;Lee, Jae Hyung
    • Tuberculosis and Respiratory Diseases
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    • 제77권5호
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    • pp.209-214
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    • 2014
  • Background: Bronchiectasis and asthma are different in many respects, but some patients have both conditions. Studies assessing the effect of bronchiectasis on asthma exacerbation are rare. The aim of this study is to investigate the effect of bronchiectasis on asthma exacerbation. Methods: We enrolled 2,270 asthma patients who were followed up in our hospital. Fifty patients had bronchiectasis and asthma. We selected fifty age- and sex-matched controls from the 2,220 asthma patients without bronchiectasis, and assessed asthma exacerbation and its severity based on the annual incidence of total asthma exacerbation, annual prevalence of steroid use, and frequency of emergency room visits and hospitalizations due to asthma exacerbation in each group. Results: Fifty patients (2.2%) had bronchiectasis and asthma. The annual incidence of asthma exacerbation was higher in patients with asthma and bronchiectasis than in patients with asthma alone ($1.08{\pm}1.68$ vs. $0.35{\pm}0.42$, p=0.004). The annual prevalence of steroid use ($0.9{\pm}1.54$ vs. $0.26{\pm}0.36$, p=0.006) and the frequency of emergency room visits ($0.46{\pm}0.84$ vs. $0.02{\pm}0.13$, p=0.001) due to asthma exacerbation were also higher in patients with asthma and bronchiectasis than in patients with asthma alone. Conclusion: Bronchiectasis is associated with difficult asthma control.

양.한방 협진을 운영하는 종합병원 외래진료부의 공간 구성 및 면적분석에 관한 연구 (A Study on the Spatial Composition and Area Analysis of O.P.D in General Hospitals that Offer the Cooperative Treatment between Western and Oriental Medicine)

  • 박유선;박재승
    • 한국실내디자인학회논문집
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    • 제19권2호
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    • pp.216-224
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    • 2010
  • This study aims to examine a special type of hospital known as Western Oriental medicine treatment designed to provide the best treatment by combining the advantages of Western and Oriental medicine, The actual conditions of the organizations and operations of O.P.D and how the cooperative treatment between Western and Oriental medicine is conducted at general hospitals that operate the cooperative treatment by applying a drawing analysis and an area analysis, and provide materials that help design hospitals that offers the cooperative treatment based on the information. According to the results of this study, the forms of the cooperative treatment between Western and Oriental medicine included several methods; to operate the cooperative center separately between an Oriental hospital and a general hospital, to operate the cooperative hospital, using several floors for an Oriental hospital inside a general hospital, and to operate the cooperative center in specialized centers inside a general hospital and the type of cluster that offers the cooperative treatment in specialized centers is known as the best appropriate treatment.

VALUATION AND HEDGING OF OPTIONS WITH GENERAL PAYOFF UNDER TRANSACTIONS COSTS

  • Choi, Hyeong-In;Heath, David;Ku, Hye-Jin
    • 대한수학회지
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    • 제41권3호
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    • pp.513-533
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    • 2004
  • We present the pricing and hedging method for options with general payoffs in the presence of transaction costs. The convexity of the payoff function-gamma of the options- is an important issue under transaction costs. When the payoff function is convex, Leland-style pricing and hedging method still works. However, if the payoff function is of general form, additional assumptions on the size of transaction costs or of the hedging interval are needed. We do not assume that the payoff is convex as in Leland 〔11〕 and the value of the Leland number is less (bigger) than 1 as in Hoggard et al. 〔10〕, Avellaneda and Paras 〔1〕. We focus on generally recognized asymmetry between the option sellers and buyers. We decompose an option with general payoff into difference of two options each of which has a convex payoff. This method is consistent with a scheme of separating out the seller's and buyer's position of an option. In this paper, we first present a simple linear valuation method of general payoff options, and also propose in the last section more efficient hedging scheme which costs less to hedge options.

요양병원과 종합병원 간호사의 노인전문간호사에 대한 역할기대와 노인전문간호 수행 정도 비교 (The Role-expectations of Gerontological Nurse Practitioners and Performance of Gerontological Nursing by Nurses in Long Term Care Hospitals and General Hospitals)

  • 이혜진;김계하
    • 성인간호학회지
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    • 제26권6호
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    • pp.642-652
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    • 2014
  • Purpose: The purpose of this study was to compare the role-expectations of gerontological nurse practitioners and performance of gerontological nursing by nurses in long term care hospitals and general hospitals. Methods: Subjects were 200 nurses; 100 nurses from long term care hospitals where as 100 nurses from general hospitals. The subjects completed a questionnaire on general characteristics, role-expectations of gerontological nurse practitioners, and performance of gerontological nursing by nurses. Data were collected from February to March 2013 and analyzed using SPSS/WIN 18.0 version program in order to perform descriptive statistics, independent t-test, and one-way ANOVA. Results: Results indicated that there were significant differences in the role-expectations of gerontological nurse practitioners and performance of gerontological nursing between nurses from long term care hospitals and those from general hospitals. Conclusion: Nurses in general hospitals showed significantly higher role expectations than nurses in long term care hospitals. Therefore it is necessary to spread the knowledge on the roles of gerontological nurse practitioners and the nurse practitioners system to nurses in long term care hospitals.

Apoptosis of Colorectal Cancer UTC116 Cells Induced by Cantharidinate

  • Liu, Bin;Gao, Hai-Cheng;Xu, Jing-Wei;Cao, Hong;Fang, Xue-Dong;Gao, Hai-Mei;Qiao, Shi-Xing
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권8호
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    • pp.3705-3708
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    • 2012
  • Effects of Cantharidinate on apoptosis of human colorectal cancer UTC-116 cells were investigated by means of 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay, H and E staining, flow cytometry, and Raman Spectra analysis. The results showed Cantharidinate to exert inhibitory action on proliferation of human colorectal cancer UTC-116 cells, inducing apoptosis, arresting cells in G1 phase, with decline of S and G2 phases. In addition, the results of Raman spectrum showed significant changes in the UTC-116 cells chemical structure with stretching after the application of Cantharidinate. Taken together, these results suggest that the treatment of human colorectal cancer with Cantharidinate may be associated with multiple molecular mechanisms for apoptosis. Furthermore, similar to fluorouracil, Cantharidinate should be considered as novel assistant drug for controlling the growth of human colorectal cancer UTC-116 cells.

Acute Osteomyelitis in the Hand Due to Dog Bite Injury: A Report of 3 Cases

  • Lee, Ryun;Lee, Hee Young;Kim, Ji Hyun;Han, Yea Sik;Kim, Dong Chul;Tark, Kwan Chul
    • Archives of Plastic Surgery
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    • 제44권5호
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    • pp.444-448
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    • 2017
  • As many people keep small dogs as pets, dog bites are common injuries, accounting for approximately 80%-90% of all animal bite injuries. These injuries usually occur on the upper extremities, most commonly on the fingers. Most of these injuries appear as simple lacerations or abrasions of the skin. Common symptoms include inflammatory reactions of the soft tissue, such as pain, swelling, erythema, and cellulitis. However, the complications of small dog bites may include joint or cartilage injuries, including acute osteomyelitis. Once osteomyelitis develops, it is difficult to diagnose since it has a latency period of approximately 2 weeks. Plain radiography, magnetic resonance imaging, and 3-phase bone scans should be performed when acute osteomyelitis is suspected, and broad-spectrum empiric antibiotic treatment should be administered for approximately 8-12 weeks. We report 3 very rare cases of acute osteomyelitis that occurred after a dog bite injury.

어머니와 미혼딸의 가정관리능력에 관한 연구 (A Study on the Home Management Ability of Mothers and their unmarried Daughters)

  • 지금수
    • 대한가정학회지
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    • 제28권4호
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    • pp.155-176
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    • 1990
  • The purpose of this study is to investigate the influential factors to home management ability of mothers and their unmarried daughters through researching the relationship of their home management ability. It would provide the basic data for the direction of Home Economics Education. The subjects were 653, from 20 to 30 years of unmarried women and their mothers in Chonbuk province. The questionaire was used to measure their Home Management ability. The measured areas were planing, creativity, consumption management, housework, evaluation, and human relation. The question items were respectively 6 and totally 36. Spss was used for the statistic. Frequency, Percentage, Means, Standard Deviation were used for general understanding. For data analysis, F-test, Pearson Product-moment Correlation, Duncan's Multiple Range Test, Stepwise Multi-regression Analysis were used. Lastly, the research pattern was examined by Path Analysis. The results were as follows. 1. The importnat influential factors to mother's home management ability were their schooling level and their perceived socio-economic status among the general factors(age, shooling level, perceived socio-economic status) and the family atmosphere factors(monthly income, family type). 2. The important influential factors of unmarried daughter's home management ability were the monthly income of their family and the socio-economic status perceived by them, among their mother's general factors, family atmohphere factors, their own general factors(age, schooling level, perceived socio-economics status, occupation, growing place). 3. The influence of mother's home management ability on unmarried daughter's home management ability was much more remarkable than mother's general factors, family atmosphere factors and unmarried daughter's general factors.

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Optimal protocol for teleconsultation with a cellular phone for dentoalveolar trauma: an in-vitro study

  • Park, Won-Se;Lee, Hae-Na;Jeong, Jin-Sun;Kwon, Jung-Hoon;Lee, Grace H.;Kim, Kee-Deog
    • Imaging Science in Dentistry
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    • 제42권2호
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    • pp.71-75
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    • 2012
  • Purpose : Dental trauma is frequently unpredictable. The initial assessment and urgent treatment are essential for dentists to save the patient's teeth. Mobile-phone-assisted teleconsultation and telediagnosis for dental trauma could be an aid when a dentist is not available. In the present in-vitro study, we evaluated the success rate and time to transfer images under various conditions. Materials and Methods : We analyzed the image quality of cameras built into mobile phones based on their resolution, autofocus, white-balance, and anti-movement functions. Results : The image quality of most built-in cameras was acceptable to perform the initial assessment, with the autofocus function being essential to obtain high-quality images. The transmission failure rate increased markedly when the image size exceeded 500 kB and the additional text messaging did not improve the success rate or the transmission time. Conclusion : Our optimal protocol could be useful for emergency programs running on the mobile phones.

턱벼각 절골술 후 발생한 괴사근막염의 치험례 (A Case of Necrotizing Fasciitis of Lower Leg Following Mandible Angle Ostectomy)

  • 이원;강상윤;홍성관;이승룡;조상헌;한병기
    • Archives of Plastic Surgery
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    • 제32권5호
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    • pp.663-666
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    • 2005
  • Mandible angle ostectomy is the most widely-operated facial contour surgery. We experienced a rare case of necrotizing fasciitis of the lower leg following mandible angle ostectomy. A 20 years old female visited our department 5 days after mandible angle ostectomy. At the time, she was diagnosed as sepsis and on her 2nd admission day, she was diagnosed as necrotizing fasciitis on her left leg. She was treated by fasciotomy and necrotized tissue removal. Necrotizing fasciitis is a rare complication of any kinds of operation but once it develops, it causes fatal results, especially to cosmetic surgeries. Early diagnosis and aggressive operation is known as only treatment for the disease.