• 대한약리학회지
• /
• 제10권2호
• /
• pp.13-23
• /
• 1974

Results of an experiment on the general behavior of rats in order to explore the possible pharmacological actions of Panax Ginseng upon the central nervous system can be summarized as follows: 1) The rats treated with Ginseng-saponin intraperitoneally with the doses of 50 or 100 mg/kg show the decreased sleeping component and increase in lying and grooming component and walking and rearing component of general behavior. 2) There are no difference between control group and saline treated group in pattern of general behavior components. 3) In the Ginseng-saponin treated groups, the amphetamine stimulated walking and rearing component of genenarl behavior are reduced but lying and grooming component are elevated. 4) Ginseng-saponin shows very low acute toxicity in mice. The $LD_{50}$ in mice of 24 hours after intraperitoneal injection was 795 mg/kg. From the above findings, it is to suggest that the Ginseng saponin might stimulate the central nervous system but its mode of action appears to be different from that of amphetamine. And the effects of Ginseng saponin may be varied depending on various experimental situation or condition of animals.

• Computers and Concrete
• /
• 제1권3호
• /
• pp.303-324
• /
• 2004

The Component-Based Software Development (CBSD) has established itself as a sound paradigm in the software engineering discipline and has gained wide spread acceptance in the industry. The CBSD relies on the availability of standard software components for encapsulation of specific functionality. This paper presents the framework for the development of a software component for the design of general member cross-sections. The proposed component can be used in component-based structural engineering software or as a stand-alone program developed around the component. This paper describes the use-case scenarios for the component, its design patterns, object models, class hierarchy, the integrated and unified handling of cross-section behavior and implementation issue. It is expected that a component developed using the proposed patterns and model can be used in analysis, design and detailing packages to handle reinforced concrete, partially prestressed concrete, steel-concrete composite and steel sections. The component can provide the entire response parameters of the cross section including determination of geometric properties, elastic stresses, flexural capacity, moment-curvature, and ductility ratios. The component can also be used as the main computational engine for stand-alone section design software. The component can be further extended to handle the retrofitting and strengthening of cross-sections, shear and torsional response, determination of fire-damage parameters, etc.

• 대한전기학회논문지:시스템및제어부문D
• /
• 제52권1호
• /
• pp.64-75
• /
• 2003

Medical image segmentation is the process by which an original image is partitioned into some homogeneous regions like bones, soft tissues, etc. This study demonstrates an automatic medical image segmentation technique based on independent component analysis. Independent component analysis is a generalization of principal component analysis which encodes the higher-order dependencies in the input in addition to the correlations. It extracts statistically independent components from input data. Use of automatic medical image segmentation technique using independent component analysis under the assumption that medical image consists of some statistically independent parts leads to a method that allows for more accurate segmentation of bones from CT data. The result of automatic segmentation using independent component analysis with square test data was evaluated using probability of error(PE) and ultimate measurement accuracy(UMA) value. It was also compared to a general segmentation method using threshold based on sensitivity(True Positive Rate), specificity(False Positive Rate) and mislabelling rate. The evaluation result was done statistical Paired-t test. Most of the results show that the automatic segmentation using independent component analysis has better result than general segmentation using threshold.

• Journal of the Korean Data and Information Science Society
• /
• 제19권2호
• /
• pp.421-429
• /
• 2008

We consider a general semiparametric additive risk model that consists of three components. They are parametric, purely and smoothly nonparametric components. In parametric component, time dependent term is known up to proportional constant. In purely nonparametric component, time dependent term is an unknown function, and time dependent term in smoothly nonparametric component is an unknown but smoothly function. As an estimation method of this model, we use the weighted least square estimation by Huffer and McKeague (1991). We provide an illustrative example as well as a simulation study that compares the performance of our method with the ordinary least square method.

• 산업경영시스템학회지
• /
• 제11권18호
• /
• pp.35-39
• /
• 1988

In general, the characteristics of components which consist of multi component system can not be the same. This paper proposes a maintenance model of multi-component system according to the characteristics of each component. In this paper multi-component system is divided into three components-critical component, major component and minor component, respectively. Then we determine the optimal age replacement time of the system which minimizes total maintenance cost. Numerical examples are shown to illustrate the result.

• Communications for Statistical Applications and Methods
• /
• 제14권1호
• /
• pp.205-213
• /
• 2007

In this paper, the normal mixture model subjected to general linear restriction for component-means based on linear regression is proposed, and its fitting method by EM algorithm and Lagrange multiplier is provided. This model is applied to gene clustering of microarray expression data, which demonstrates it has very good performances for real data set. This model also allows to obtain the clusters that an analyst wants to find out in the fashion that the hypothesis for component-means is represented by the design matrices and the linear restriction matrices.

• 대한기계학회논문집B
• /
• 제23권2호
• /
• pp.198-209
• /
• 1999

This study reports the selection of dependent variables for momentum equations in general curvilinear coordinates. Catesian, covariant and contravariant velocity components were examined for the dependent variable. The focus of present study is confined to staggered grid system Each dependent variable selected for momentum equations are tested for several flow fields. Results show that the selection of Cartesian and covariant velocity components intrinsically can not satisfy mass conservation of control volume unless additional converting processes ore used. Also, Cartesian component can only be used for the flow field in which main-flow direction does not change significantly. Convergence rate for the selection of covariant velocity component decreases quickly as with the increase of non-orthogonality of grid system. But the selection of contravariant velocity component reduces the total mass residual of discretized equations rapidly to the limit of machine accuracy and the solutions are insensitive to the main-flow direction.

• 대한정형도수물리치료학회지
• /
• 제10권2호
• /
• pp.73-82
• /
• 2004

Objectives : In order to develop the measuring tool of visual display terminal (VDT) syndrome and investigate the variables affecting the development of VDT syndrome. Methods : A questionnaire study accompanied with the evaluation of working environment was performed with 42 VDT users from banking operations. Results : As a results of analysis with data colleted by newly developed questionnaire, VDT syndrome included five factors named as eye-related component, and psychological component. general body discomfort component. musculoskeletal component, and skin-related component. The scores of eye-related symptoms was 15.17, scores of psychological symptoms was 7.36, scores of general body discomfort symptoms was 10.52, scores of musculoskeletal symptoms was 9.38, scores of skin-related symptoms was 3.67, and total scores was 46.10. Scores of 2.05 eye fatigue in the level of eye-related symptoms were higher significantly. Scores 50.52 of female was statistically higher than scores 41.67 of male. Conclusions : The subjective symptoms of VDT syndrome scores was significantly associated with gender and age.

• 한국자동차공학회논문집
• /
• 제25권3호
• /
• pp.344-349
• /
• 2017

Suspension noise from under a passenger car is one of the important factors that impact the perceptual quality for drivers. However, it is difficult to validate this by component level testing in the early stage of development, because suspension noise caused by interaction of the related parts has been found at saleable vehicles late during development or at the manufacturing stage, when many customers have already filed for claims. This study proposed a validation testing under research by the DFSS process that enables reproduction of vehicle level noise by component level testing using a shock absorber with the related parts, such as urethane bumper and top mount. This study also developed a compromised test matrix while analyzing the noise factors through experimental design and analysis of variance to determine what factors can affect noise. Based on this study, we expect that the vehicle level and customer claim can be validated during initial development timing by a more reliable component noise validation test.

• 대한기계학회논문집
• /
• 제17권8호
• /
• pp.1883-1897
• /
• 1993

Interactive computer-aided analysis of mechanical systems has recently been undergoing an evolution due to highly efficient computer graphics. The industrial implementation of state-of-the-art analytical developments in mechanisms has been facilitated by computer-aided design packages because these rigid-body mechanism analysis programs dramatically reduce the time required for linkage design. This paper proposes a component modular approach to computeraided kinematic motion analysis for general planar multiloop mechanisms. Most multiloop mechanisms can be decomposed into serveral components. The kinematic properties (position, velocity, and acceleration) of every node can then be determined from the kinematic analysis of the corresponding component modules by a closed-form solution procedure. In this paper, 8 types of modules are defined and formulations for kinematic analysis of the component modules are derived. Then a computer-aided kinematic analysis program is developed using the proposed approach and the solution procedure of an example shows the effectiveness and accuracy on the approach.