• 제목/요약/키워드: general: methods

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Meta-analysis of the Efficacy of Sorafenib for Hepatocellular Carcinoma

  • Wang, Zhao;Wu, Xiao-Ling;Zeng, Wei-Zheng;Xu, Gui-Sen;Xu, Hui;Weng, Min;Hou, Juan-Ni;Jiang, Ming-De
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권2호
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    • pp.691-694
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    • 2013
  • Purpose: By carrying out a meta-analysis of randomized controlled trials that compared sorafenib or combined chemotherapy with placebo or combined chemotherapy, the effectiveness of sorafenib in hepatocellular carcinoma was evaluated in the present study, which also provided clinical practice guidelines of evidence-based-medicine. Methods: We reviewed PubMed citations concerning sorafenib treating hepatocellular carcinoma in randomized controlled trials from Jan 2000 to July 2012. All the literature was extracted by Cochrane systematic reviews and underwent meta-analysis with RewMan 5.0 software. Results: Finally, four papers documenting randomized controlled studies were included. Compared with controls, sorafenib was shown to significantly increase overall survival (OS), time to progression (TTP), and disease control rates (DCR), but not the time to symptom progression (TTSP) in hepatocellular carcinoma patients. The incidence of grade-III/IV adverse reactions, including hand-foot-skin reactions, diarrhea, hypertension and skin rash or desquamation, in sorafenib treatment group was higher than that in controls. However, there was no significant difference in the incidence of hypodynamia between the two groups. Conclusions: Sorafenib exerts significant curative effects in hepatocellular carcinoma.

의료기관의 일반병동, 성인 중환자실, 신생아 중환자실의 간호등급 변화 (Changes in Nurse Staffing Grades in General Wards and Adult and Neonatal Intensive Care Units)

  • 홍경진;조성현
    • 임상간호연구
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    • 제23권1호
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    • pp.64-72
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    • 2017
  • Purpose: This study aimed to explore the distributions of nurse staffing grades and to report changes in staffing grades in general wards and adult and neonatal intensive care units(ICUs) by hospital type and location. Methods: Data collected from the Health Insurance Review and Assessment Service were analyzed. Nurse staffing was categorized from grades 1 to 6 or 7 for general wards, 1 to 9 for adult ICUs, and 1 to 4 for neonatal ICUs based on the nurse-to-bed ratio. Results: The staffing grade for the general wards improved during 2008-2016 in 69.8% of the tertiary hospitals, 58.5% of the general hospitals, and 31.7% of the non-general hospitals. The adult ICUs at tertiary hospitals exhibited a greater improvement in staffing grades (48.8%) than did those of general hospitals (44.2%) during 2008-2015. Tertiary hospitals in non-capital regions showed a greater improvement than those in the capital region. The majority of neonatal ICUs (67.1%) had no change in the staffing grade during 2008-2015. Conclusion: Improvements in nurse staffing differed by hospital type and location. Government policies to improve nurse staffing in non-tertiary hospitals and those in non-capital regions are required to reduce variations in nurse staffing.

Delayed awakening time from general anesthesia for dental treatment of patients with disabilities

  • Choi, Junglim;Kim, Seungoh
    • Journal of Dental Anesthesia and Pain Medicine
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    • 제21권3호
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    • pp.219-226
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    • 2021
  • Background: Patients with disabilities often require general anesthesia for dental treatment because of their cooperative or physical problems. Since most patients with disabilities take central nervous system drugs, the management of recovery status is important because of drug interactions with anesthetics. Methods: The anesthesia records of patients under general anesthesia for dental treatment were reviewed, and data were collected. Healthy patients under general anesthesia for dental phobia or severe gagging reflex were designated as the control group. Patients with disabilities were divided into two groups: those not taking any medication and those taking antiepileptic medications. The awakening time was evaluated in 354 patients who underwent dental treatment under general anesthesia (92 healthy patients, 183 patients with disabilities, and 79 patients with disabilities taking an antiepileptic drug). Based on the data recorded in anesthesia records, the awakening time was calculated, and statistical processes were used to determine the factors affecting awakening time. Results: Significant differences in awakening time were found among the three groups. The awakening time from anesthesia in patients with disabilities (13.09 ± 5.83 min) (P < 0.0001) and patients taking antiepileptic drugs (18.18 ± 7.81 min) (P < 0.0001) were significantly longer than in healthy patients (10.29 ± 4.87 min). Conclusion: The awakening time from general anesthesia is affected by the disability status and use of antiepileptic drugs.

가사노동의 경제적 가치평가에 관한 연구 (Estimates of the Economic Value of Houshold Work by Fulltime Home Makers)

  • 김선희
    • 대한가정학회지
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    • 제28권2호
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    • pp.73-89
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    • 1990
  • The aim of the present study is to estimates the economic value of household work done by fulltime home makers, using alternative methods of valuation household work in Pusan Korea. Eight findings, five different methods -Self Estimation by Home Makers, Reservation Wage, Opportunity Cost, Individual function Cost, Replacement Cost(Visiting Housekeeper, Housekeeper, General Managemet, Housekeeper & General Management)- are tried for the estimation of economic value of household work. The results of this study can be outlined as follows : 1) The economic value of household work varies substantially by the methods of estimating. The averages are : 2) The economic value of household work varies with the level of education, ages, the number of children, the stage of FLC in all method of estimation, and the level of income in self estimation by home makers, Reservation wage. Specially, FLC revealed good explanation variable in method of estimation as input household work time. 3) The gap between two-day survey and three-day survey in household work time questionaire didn't so much.

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A Study on Creative and Convergent SW Education Programs for improving Computational Thinking

  • Lee, Myung-Suk
    • 한국컴퓨터정보학회논문지
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    • 제22권8호
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    • pp.93-100
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    • 2017
  • After the fourth industrial revolution came along, SW education to improve creativity and problem-solving ability began in elementary, middle, and high schools first and then in universities as well positively; however, research on the curriculum or what it has to pursue is not yet enough. Here, this study will investigate the current status of SW education provided in software-oriented schools operated in universities and also given as cultural studies in general universities and examines the curriculum or the standard plan for education. In most schools, it is operated as similar subject names, and diverse methods are tried on- and off-line to cultivate computing thinking skills. Also, to study SW education programs that can be operated in the general cultural courses of universities and find out how to utilize them, this author suggests the goal setting, educational contents, and teaching methods for SW education. As follow-up tasks, it will be needed to apply the suggested programs to the field and find out new evaluation methods in order to cultivate creative and convergent persons of ability.

병원 활동기준원가계산 모형의 적용방식과 도입전략 (Strategies for Application and Introduction of Activity Based Costing for Korean Hospitals)

  • 선승훈
    • 한국병원경영학회지
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    • 제4권1호
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    • pp.96-128
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    • 1999
  • This research has a purpose to develop strategies for application and introduction of activitiy based costing for Korean hospitals. A 700 bed-sized general hospital in Taejon was chosen to conduct this study. The conventional costing and ABC methods were simultaneously applied to the Obstetrics & Gynecology department, using data surveyed from June 21 to 30, 1998. The difference of two costing methods' results were analyzed and ABC's superiority was recognized. It showed that the new ABC model was more rational, fair, and objective in allocating indirect costs. The strategies to introduce ABC model to hospitals were suggested as followings: 1)a committee to manage ABC should be organized; 2)education for the employees about costing and cost saving should be provided; 3)the computerized ABC program should be developed; and 4)more advanced and rigourous methods to identify activities and measure the resource consumption should be developed.

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Comparison of EM and Multiple Imputation Methods with Traditional Methods in Monotone Missing Pattern

  • Kang, Shin-Soo
    • Journal of the Korean Data and Information Science Society
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    • 제16권1호
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    • pp.95-106
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    • 2005
  • Complete-case analysis is easy to carry out and it may be fine with small amount of missing data. However, this method is not recommended in general because the estimates are usually biased and not efficient. There are numerous alternatives to complete-case analysis. A natural alternative procedure is available-case analysis. Available-case analysis uses all cases that contain the variables required for a specific task. The EM algorithm is a general approach for computing maximum likelihood estimates of parameters from incomplete data. These methods and multiple imputation(MI) are reviewed and the performances are compared by simulation studies in monotone missing pattern.

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부산시내 공업고등학교 학생의 스트레스 생활사건과 대처방법에 관한 연구 (A Study of Stressful Events and the Coping Methods of Technical High School Students in Pusan)

  • 김이순
    • 한국학교보건학회지
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    • 제11권1호
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    • pp.75-90
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    • 1998
  • The purpose of this study is to identify the stressful events, students their coping methods, and to provide data which maintain and promote healthy students, mentally and physically, The data were collected from total of 481 students from a technical high school in Pusan The Questionnair survey was done from February 2 to February 14, 1988 Analysis of the data was done using descriptive statistics, frequency, ANOVA and a t-test, The findings of the research were as follows: 1) As to the general characteristics of the 481 subjects, 376 (78.2%) were boys and 105 (218%) were girls In terms of health, 93% were in poor health From the results, It seems that when students have problems, many of them seek advice from their friends while nobody seeks advice from their teachers. 2) This study found that most students have many stressful events. In boy students, the most serious events were the following, 'death of parents', 'death of brother or Sister', 'divorce of parents' In girl students, the most serious erents were the following: 'death of brother or sister', 'death or serious sickness of friend', 'death of parents'. 3) To cope With these events, boy students used positive ways such as the following, 'to listen to music', 'to bear', 'to think through the problems' To cope with stressful events, girl students used the following positive methods 'to listen to music', 'to talk with others', 'to sing', 'to sleep' and 'to weep', A small percentage of students used the following negative methods 'to drink alcohol', 'to skip school' and 'to escape from home' 4) The relationship between stressful events and general characteristics represented Significant differences in academic scores (F=1.440, p=0008), health state (F=1.388, p=0.015), and relationship with parents (F=1.685, p=0.000) The relationship between general characteristics and coping methods represented a significant difference in sex (t=-3.100, p=0.002).

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다계층 분배형 공급사슬에서 주문리스크의 근사적 계산방법과 비용개선효과 (An Approximate Order Risk Evaluation Method for the General Multi- Echelon Distribution Supply Chain)

  • 서용원
    • 한국경영과학회:학술대회논문집
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    • 대한산업공학회/한국경영과학회 2004년도 춘계공동학술대회 논문집
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    • pp.636-647
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    • 2004
  • The objective of this paper is to provide an improved reorder decision policy for general multi-echelon distribution systems utilizing the shared stock information. It has been known that traditional reorder policies sometimes show poor performance in distribution systems. Thus, in our previous research we introduced the order risk policy which utilizes the shared stock information more accurately for the 2-echelon distribution system and proved the optimality. However, since the real world supply chain is generally composed with more than 2 echelons, we extend the order risk policy for the general multi-echelon systems. Since the calculation of the exact order risk value for general multi-echelon systems is very complex, we provide two approximation methods for the real-time calculation. Through the computational experiment comparing the order risk policy with the existing policies under various conditions, we show the performance of the order risk policy and analyze the value of the shared stock information varying with the characteristics of the supply chain.

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다계층 분배형 공급사슬의 운영 개선을 위한 주문리스크 기반의 재주문정책과 실용적 근사방법 (An Improved Reorder Policy for the General Multi-Echelon Distribution Supply Chain based on the Order Risk)

  • 서용원
    • 한국경영과학회:학술대회논문집
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    • 한국경영과학회 2003년도 추계학술대회 및 정기총회
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    • pp.159-165
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    • 2003
  • The objective of this paper is to provide an improved reorder decision policy for general multi-echelon distribution systems utilizing the shared stock information. Since it has been known that traditional reorder policies sometimes show poor performance in distribution systems, in our previous research we introduced the order risk policy which utilizes the shared stock information more accurately f3r the 2-echelon distribution system and proved the optimality. However, since the real world supply chain is generally composed with more than 2 echelons, we extend the order risk policy for the general multi-echelon systems. Since the calculation of the exact order risk value fur general multi-echelon systems is very complex, we provide two approximation methods. Through the computational experiment comparing the order risk policy with the existing policies under various conditions, we show the performance of the order risk policy and analyze the value of the shared stock information varying with the characteristics of the supply chain.

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