• Korean Journal of Veterinary Research
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• v.45 no.2
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• pp.255-261
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• 2005

The purpose of this study is to compare hepatotoxicity of each treatment for dermatophytosis; one is the administration of the ketoconazole only and the other, ketoconazole with diphenyl-dimeththyl-dicarboxylate. Have chosen the range of 14-24 months of healthy dogs divided by two groups (group 1 and group 2) for the experiment of which test proved positive in dermatophytosis diagnosis and showed normal reaction in terms of physical examination, blood chemistry and especially of liver function. Group 1 was administrated ketoconazole orally at 10 mg/kg/day and of same dose of ketoconazole with diphenyl-dimethyl-dicarboxylate for group 2. After administering, we have tested two groups by blood collecting every one week in order to check the differences of hepatotoxicity state through AST, ALT and r-GTP, the barometers of liver function which lasted for 12 weeks. Moreover, tested Indocyanine Green (ICG), known as susceptible gauge of function of excretion before starting the experiment and tested ICG as well after 12 weeks. The experiment of result the value of group 1 in AST, ALT and r-GTP has been highly rised after administering ketoconazole for 10 weeks meanwhile, of group 2 has shown a steady state troughout the whole experiment. For ICG test, we injected 0.5 mg/kg of ICG into a vein for both groups and tested the retention rate at regular interval of 15, 30, 45 minutes. The results of retention rate in two groups were similar to before the drug administration. However, after 12 weeks the retention rate of group 1 has been delayed, on the other hand, retention rate of group 2 were a steady state. In conclusion, the administration of ketoconazole only for a long period of time induced hepatotoxicity where as, the administration of ketoconazole with diphenyl-dimethyl-dicarboxylate didn't induce hepatotoxicity. Therefore, when doctors prescribes for a dog with dermatophytosis should not administrate ketoconnazole itself but with diphenyl-dimethyl-dicarboxylate and one who has abnormal condition of liver function should not be prescribed ketoconazole treatment. If there is a case needed to prescribe ketoconazole treatment, the regular monitoring should be accompanied by at the same time.

• Journal of Acupuncture Research
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• v.19 no.1
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• pp.84-91
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• 2002

Objective : The purpose of this report is to use more Shin Jong Gyuk of Ohaeng Acupuncture acupunture treatment clinically by comparing the Improvement of Back pain and Sciatica between Common Acupuncture treatment Group and Common Acupuncture with Shin Jong Gyuk of Ohaeng Acupuncture treatment Group. Methods : This study was carried out on 40 patients with Back pain and Sciatica who were hospitalized in Dongshin Univ. Oriental Hospital from 1st, April, 2001 to Tenth, November, 2001. Group A of 20 patients were taken both common acupunture treatment and Shin Jong Gyuk of Ohaeng Acupuncture treatment. And Group B of 20 patients were only taken common acupunture treatment. And after 10 days of admission, we checked and compared VAS(Visual Analogue Scale) and improvement index out of these two groups. SPSS(Statistical Program for Sdcial Science) for Window was used for a statistical analysis and the independent T-test was performed to gauge the improvement of VAS(Visual Analogue Scale) and improvement index out of these two groups, in which case, value of P below 0.05 is considered as useful. Results : The result of the VAS(Visual Analogue Scale) and improvement index of comparision analysis between two groups after 10 days, shows that the improvement of Back pain and Sciatica in Common Acupuncture treatment with Shin Tong Gyuk of Ohaeng Acupuncture treatment Group is more effective than that in Common Acupuncture treatment Group. (independent T-test improvement index P=0.21, VAS P=0.00)

• The Journal of Advanced Prosthodontics
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• v.1 no.1
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• pp.19-25
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• 2009

STATEMENT OF PROBLEM. Primary stability at the time of implant placement is related to the level of primary bone contact. The level of bone contact with implant is affected by thread design, surgical procedure and bone quality, etc. PURPOSE. The aim of this study was to compare the initial stability of the various taper implants according to the thread designs, half of which were engaged to inferior cortical wall of type IV bone(Group 1) and the rest of which were not engaged to inferior cortical wall(Group 2) by measuring the implant stability quotient(ISQ) and the removal torque value(RTV). MATERIAL AND METHODS. In this study, 6 different implant fixtures with 10 mm length were installed. In order to simulate the sinus inferior wall of type IV bone, one side cortical bone of swine rib was removed. 6 different implants were installed in the same bone block following manufacturer s recommended procedures. Total 10 bone blocks were made for each group. The height of Group 1 bone block was 10 mm for engagement and that of group 2 was 13 mm. The initial stability was measured with ISQ value using Osstell $mentor^{(R)}$ and with removal torque using MGT50 torque gauge. RESULTS. In this study, we found the following results. 1. In Group 1 with fixtures engaged to the inferior cortical wall, there was no significant difference in RTV and ISQ value among the 6 types of implants. 2. In Group 2 with fixtures not engaged to the inferior cortical wall, there was significant difference in RTV and ISQ value among the 6 types of implants(P < .05). 3. There was significant difference in RTV and ISQ value according to whether fixtures were engaged to the inferior cortical wall or not(P < .05). 4. Under-drilling made RTV and ISQ value increase significantly in the NT implants which had lower RTV and ISQ value in Group 2(P < .05). CONCLUSIONS. Without being engaged to the inferior cortical wall fixtures had initial stability affected by implant types. Also in poor quality bone, under-drilling improved initial stability.

• Journal of the korean academy of Pediatric Dentistry
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• v.32 no.3
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• pp.481-490
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• 2005

The aim of this study was to investigate the relationship between the C-factor and shrinkage strain values of composite resin and examine the strain values in different incremental filling techniques. The strain gauge method was used for measurement of polymerization shrinkge strain. Experiment was divided two step. In a first experiment, we compared with strain value in three different depth (2mm, 3mm, 4mm) and microhardness of each samples after 24hours were measured. In a second experiment, we examined the strain values in five different filling techniques(Group 1: bulk filling, Group 2: oblique incremental filling, Group 3: horizontal incremental filling, Group 4: vertical incremental filling, Group 5: lining of flowable resin and bulk filling) The results of the present study can be summarized as follows: 1. Composite resin in acrylic molds showed the initial expansion at the early phase of polymerization. 2. Contraction stress was not revealed significant difference between depth of 2mm and 3mm(P>0.05). 3. Contraction stress in sample of 4mm was showed the lowest value(P<0.05). 4. Microhardness of specimen was revealed more difference between upper and lower surface in depth of 4mm than 2 and 3mm(P<0.05). 5. Lining of flowable resin and bulk filling (Group 5) was showed the lowest contraction stress, Group 2 and 3 was showed the highest contraction stress(P<0.05). On the basis above results, the stress that result from the polymerization shrinkage, when incremental curing techniques are used, showed that there is no advantage in incremental placement and curing.

• The korean journal of orthodontics
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• v.33 no.6 s.101
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• pp.437-451
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• 2003

The purpose of this study was to measure maximum bite force and to investigate its relationship with anteroposterior, vertical, and transverse facial skeletal measurements. From among the dental students at the College of Dentistry, forty subjects (26 male and 14 female) were selected. With two sets of strain gauge, maximum bite force at the right and left first molars and anterior teeth was measured in the morning and afternoon. After taking lateral and posteroanterior cephalograms, fifty and nineteen variables were evaluated, respectively Paired t-tests and an independent t-test were done and correlation coefficients were obtained. 1. The maximum bite force at the first molars was $68.0\pm13.9kg$. in males and $55.6\pm10.5kg$ in females (p<0.05) while the force at the anterior teeth was $8.4\pm4.9kg\;and\;1.1\pm3.4kg$ respectively (p<0.05). 2. Some tendency for a greater value of maximum bite force at the preferred side was observed but not statistically significant (p>0.05). 3. Significant difference was observed between the strong bite force group and the weak bite force group in some cephalometric and other measurements (p<0.05). N-S-Ar, S-Ar-Go, FH-Hl, IMPA and MMO showed a significant difference in posterior maximum bite force (P). N-S-Ar and FH-H1 also showed a significant difference in anterior maximum bite force (A). 4. Several cephalometric variables showed some correlation with maximum bite force (p<0.05). N-S-Ar, S-Ar-Go, UGA, FH-H6, FH-H1, body weight and MMO were significantly correlated with posterior maximum bite force (P). Go-Me, P-1 and IMPA were significantly correlated with anterior maximum bite force (A).

• The Journal of Korean Academy of Prosthodontics
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• v.52 no.2
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• pp.105-112
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• 2014

Purpose: The aim of present investigation was to find out the influence of several times iatrogenic mobilization in the initial stage of implant installation on bone-implant osteointegration. Materials and methods: The experimental implants (3.75 mm in diameter, 8.0 mm in length) were made of commercially pure (Grade IV) titanium, and were treated with RBM ($MegaGen^{(R)}$: Ca-P) on lower 4.0 mm part. Only lower part of implant was inserted to bone and the implants were nonsubmerged. The 130 implants (two in each tibia) were inserted into the monocortical tibias of 33 rabbits which each weighed more than 3.5 kg (Female, New Zealand White). According to the removal torque interval, the groups were divided into 13 groups, group I (1 day), group II (1 day + 2 days), group III (1 day + 2 days + 3 days), group IV (1 day + 2 days + 3 days + 4 days), group V (2 days), group VI (2 days + 4 days), group VII (2 days + 4 days + 6 days), group VIII (2 days + 4 days + 6 days + 8 days), group IX (4 days), group X (4 days + 7 days), group XI (4 days + 7 days + 10 days), group XII (4 days + 7 days + 10 days + 14 days) and control group. In the control group, the removal torque was measured at 8 weeks with a digital torque gauge (Mark-10, USA). In the experimental groups, the removal torque was given once, twice, three times or four times by experiment design before the final removal torque and the value was measured each time. The implants were then screwed back to their original positions. All the experimental groups were given a final healing time of 8 weeks after placement, in which values were compared with the control groups and the 1st, 2nd, 3rd or 4th removal torque values in each experimental group. Results: In comparison of the final removal torque tests among experimental groups, the removal torque value of experimental groups except group XII were not statistically different that of control group. And the values of group I and II were significantly higher than the values of group VI, VIII, X, XI, and XII. In addition, the values of group III, IV, and V were significantly higher than group XI and XII. In comparison of the removal torque in the each experimental group, the final removal torque were significantly higher in all groups except group VIII, X, XI, and XII. Conclusion: If sufficient healing time was allowed, a few mobilization of fixture at the very early stage after the implant placement in the rabbits didn't interrupt the final bone to implant osseointegration.

• Journal of Korean Academy of Nursing
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• v.34 no.3
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• pp.552-564
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• 2004

Purpose: This study was to develop a client health status outcome evaluation instrument, and examine content validity, reliability, construct validity, and the acceptability of this instrument. Method: A preliminary list was made of such key information as standards, criteria, indicators and measures, by means of a broad review of literature within the field. After determining the preliminary instruments, the study sought to obtain examination, consensus, and modification of two groups of experts in the home-care field. Finally, the instrument examined content validity, reliability, construct validity, and the acceptability of this instrument. Result: The tool was considered of 13 criteria, 48 indicators, and 167 detail measures. The content validity index of the tool was above 0.8 according to the expert group. Regarding the reliability of the evaluators of standards 1 and 2, the degree of agreement between evaluators was high(96.4% through 98.2%). Construct validity in this study, the difference in the mean score between the baseline point and the follow up point of each of standards 1 and 2 was significant, and the mean score of the follow up point was more than that of the baseline point. After examining the acceptability of this instrument with practice managers and home care nurses in home care institutions, a positive opinion was given of this instrument, and it was indicated that to be useful and applicable in home care practice. Conclusion: The results of evaluating client outcome will contribute to overall outcome-based quality improvement and service marketing in home care by providing a constant gauge of home care effectiveness.

• The Journal of Korean Academy of Prosthodontics
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• v.38 no.1
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• pp.98-107
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• 2000

Three linear strain gauges (KFR-02N-120-C1-23, Kyowa, Japan) were placed around the abutment of implant future and the maximum axial loads on the mandibular implants supporting over dentures were registered in experimental model when the overdenture was removed. The overdenture attachments used in this study were Round bar Hader bar, Dolder bar with and with out spacer. The retention of bar attachment was measured using universal testing machine while being con-trolled by Activating set and Deactivator except in case of the Hader bar. Simultaneously strains were recorded with the strain smart program in strain P-6000 series (Measurement group, Raleigh, USA). The maximum axial load was calculated and compared with each other. The results were as follows: 1. The amount and the timing of the maximum axial loads were different between the right and left implant in all attachment systems. 2. The retention of bar attachment except Hader bar could be adjusted but the controllability was different among the attachment systems. 3. The more the axial load, the higher the retention with Hader bar and Dolder bar without spacer. but the tendency of increase was not shown with round bar and Dolder bar with spacer.

• The korean journal of orthodontics
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• v.23 no.4 s.43
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• pp.607-618
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• 1993

If the centric prematurity occurs after orthodontic treatment, it creates centric slide regarded as a possible factor in the cause of temporomandibular disorder and/or postorthodontic relapse. The purpose of this study was to investigate the manner of centric prematurity and centric slide in postorthodantic patients. The 36 orthodontic patients who had been treated with edgewise appliance at least 3 mouths previously were used in this study. After recording centric relation by the leaf gauge technique, the centric prematurity and centric slide were studied using SAM2 articulator and mandibular position indicator. The results were as follows : 1. The highest percentage of centric prematurities were found on the second molars. 2. The buccal incline of the palatal cusp was the most frequent area of centric prematurities in the maxilla, while the lingual incline of the buccal cusp was the most frequent area in the mandible. 3. There were no trends in the direction of centric slide on the mandibular position indicator. 4. There were no significant differences in centric discrepancies between the premolar extraction and nonextraction group.

• The Journal of the Korean dental association
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• v.11 no.11
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• pp.739-744
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• 1973

The author measured the vertical dimension and the distances from Trichion to Nasion of 825 Korean adults (414 of male, 411 of female) above 21 years of age by Willis gauge. The following results were obtained. 1) The distances from subnasale to the bottom of chin were 71.4mm in male and 68.7mm in female, and those from Trichion to Nasion were 70.4mm in male and 68.0mm in female. The former were longer than the latter, and the distances in male were longer than those in female. 2) The differences between the distances from Subnasale to the bottom of chin were 1.0mm in male and 0.7mm in female. The frequencies of percentages, in which differences between the distances mentioned above were 0±1mm, were 43.0% in male, 42.6% in female, and 42.8% in total. 3) With the matter of age and sex differences, the distances from Subnasale to the bottom of chin and those from Trichion to Nasion were increasing to 31-40 age group by age, but those had a tendency of decreasing in the late age in both sexes.