• Title/Summary/Keyword: gastrointestinal time

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Ability of Modified Glucomannan to Sequestrate T-2 Toxin in the Gastrointestinal Tract of Chicken

  • Reddy, N.B.;Devegowda, G.;Shashidhara, R.G.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.2
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    • pp.259-262
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    • 2004
  • The ability of Modified Glucomannan (MG) to bind T-2 toxin (T-2) in the gastrointestinal tract has been tested in vivo by feeding 120 five-wk-old broiler chicken with the following six treatment diets, 1) Control diet; 2) Control+MG (0.1%); 3) Control+T-2 (500 ppb); 4) Control+T-2 (500 ppb)+MG (0.1%); 5) Control+T-2 (1,000 ppb) and 6) Control+T-2 (1,000 ppb)+MG (0.1%). Twenty birds were assigned to each treatment group, which had five experimental groups. Four birds of each experimental group were sacrificed at an interval of 30 min i.e. at 0, 30, 60, 90 and 120 min after feeding experimental diets. The whole gut contents of each bird were collected, dried and toxin concentration was determined. Percent T-2 recovered from the gut was significantly lower (p<0.05) in the groups fed MG at all the time intervals. The percent T-2 adsorbed by the MG at different T-2 levels (500 and 1,000 ppb) was 15.97 and 14.77, 22.53 and 22.67, 26.88 and 28.03, and 31.50 and 31.83 at 30, 60, 90 and 120 min, respectively.

Neuropharmacological study of hot water extract of the seeds of Vernonia anthelmintica Kuntze

  • Rahman, Mahbubur;Choudhuri, M Shahabuddin Kabir;Khan, Mahmud Tareq Hassan;Jabbar, Shaila;Alamgir, Mahiuddin
    • Advances in Traditional Medicine
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    • v.6 no.1
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    • pp.34-38
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    • 2006
  • The hot water extract of the seeds of Vernonia anthelmintica Kuntze (Compositae) in a dose of 10 ml/kg body weight of mice, showed significant analgesic activity on the hot plate analgesic method throughout the 4 h experimental period. The hole cross scores and the climbing out scores are of lower than the control animals. The hot water extract reduced the defecation in hole board study and significantly reduces the exploratory ambulation and head dipping behaviour. The seed also showed significant depressant activity on the exploratory ambulation of the open field scores. The drug decreased the spontaneous locomotion activity on brick-chip displacement method up to 45 min and also showed the ability to lessen the amphetamine induced hyperactivity up to 20 min. But it didn't show any effect on pentobarbital induced sleeping time test. The extract reduced gastrointestinal motility.

A Study on PET Adsorption Property of NIR Dye Using Swelling Agents (Swelling agent를 이용한 근적외선 흡수 유기색소의 polyester 흡착)

  • Kwon, Su Hyeon;Choi, Jae Hong
    • Textile Coloration and Finishing
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    • v.30 no.1
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    • pp.20-28
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    • 2018
  • The near infrared ray camouflage fabric has a near infrared ray reluctance similar to the surrounding environment and has a camouflage effect on the surrounding environment. Synthetic fibers used in military uniforms are difficult to have gastrointestinal function as general commercial dyes, unlike cellulose fibers, which use some commercial vat dyes to impart infrared gastrointestinal function. In this study, we optimized the adsorption pH, temperature and time for NIR dye application for polyester fabrics, and established the optimum concentration for the evaluation of adsorption build-up characteristics. In addition, it is difficult to adsorb it since the polyester material has a dense crystal structure and the NIR dye is bulky. Therefore, a swelling agent used for dyeing meta-aramid fibers with high Tg and high crystallinity was introduced as a separate preparation to increase the affinity to polyester, which is a hydrophobic fiber, to thereby obtain an excellent adsorption rate. As a result of comparing before and after using swelling agent, the adsorption rate difference was 10 times or more when compared with before.

The Single Incision Laparoscopic Intragastric Wedge Resection of Gastric Submucosal Tumor

  • Na, Jin-Uk;Lee, Sang-Il;Noh, Seung-Moo
    • Journal of Gastric Cancer
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    • v.11 no.4
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    • pp.225-229
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    • 2011
  • Purpose: Laparoscopic wedge resection of gastric submucosal tumor may be difficult in case of the endophytic mass or the mass located unreachable area such as cardia, and intragastric approach can be useful. We would present the experiences of the intragastric wedge resection. Materials and Methods: There were 7 patients diagnosed as gastric submucosal tumor and underwent the intragastric wedge resection at Surgery, Chungnam National University Hospital. We reviewed medical record. Results: There were 3 male and 4 female. Mean age was 65 years-old (57~73). Mean body mass index was 26.28 kg/$m^2$ (21.28~35.30). Location of lesions was 4 cardia, 2 fundus and 1 midbody, respectively. Mean operation time was 83.6 minutes (70~105). All patients were healed without any complication. Mean postoperative hospital stay was 5.4 days (4~6). Mean size was 2.7 cm (2.3~3.8). Pathologic finding was 5 gastrointestinal stromal tumor and 2 leiomyoma. Conclusions: The single incision intragastric wedge resection of gastric submucosal tumor is feasible and acceptable, especially in mass of gastric upper part.

Dientamoeba fragilis Infection in Patients with Digestive and Non-Digestive Symptoms: A Case-Control Study

  • Hawash, Yousry A.;Ismail, Khadiga A.;Saber, Taisir;Eed, Emad M.;Khalifa, Amany S.;Alsharif, Khalaf F.;Alghamdi, Saleh A.
    • Parasites, Hosts and Diseases
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    • v.58 no.2
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    • pp.129-134
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    • 2020
  • In most developing countries, Dientamoeba fragilis infection is an obscure protozoan infection. We aimed to determine a frequency and clinical importance of D. fragilis infection in Taif, Saudi Arabia. A 1-year case control study included patients with gastrointestinal (cases, n=114) or non-gastrointestinal symptoms (controls, n=90). The fecal samples were examined with the classical parasitological methods for intestinal protozoa, and by real time PCR for D. fragilis. The infection by D. fragilis was detected in 5.8% by PCR and in 4.4% patients by microscopy. The infection was identified more in control group (n=9) than in cases (n=3); a sole infection in 11 patients and mixed with Giardia in 1 patient. The other enteric parasites detected were Blastocystis sp. (8.3%), Giardia sp. (5.3%), Cryptosporidium sp. (2.9%), Entamoeba histolytica (1.4%), Entamoeba coli (0.9%) and Hymenolepis nana (0.4%). Our results tend to reinforce the need to increase awareness of D. fragilis infection in Saudi Arabia.

Epidemiology of Gastroesophageal Junction Adenocarcinoma in Korea

  • Kim, Jin-Jo
    • Journal of Gastric Cancer
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    • v.18 no.4
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    • pp.328-338
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    • 2018
  • The incidence of gastroesophageal junction adenocarcinoma (GEJAC) in Western countries has increased in recent decades, in addition to a rise in the incidence of esophageal adenocarcinoma (EAC). Gastroesophageal reflux disease (GERD), obesity, smoking, alcohol consumption, and low Helicobacter pylori (HP) infection rate have been nominated as risk factors for such cancers. Among these risk factors, the increased prevalence of GERD and obesity and the decreased prevalence of HP infection are of special interest owing to the currently increasing prevalence of GEJAC in Western countries. Although similar trends in the prevalence of GERD, obesity, and HP infection are observed in Asian countries after a time lag from Western countries, it is still uncertain if the prevalence of GEJAC in Asian countries is increasing, especially in Korea. The incidence of GERD in Korea is currently increasing; it was below 3% in the 1990s. The incidence of obesity in the Korean population is increasing owing to the adoption of westernized lifestyles, including food preferences, and the HP infection rate in Korea is known to be decreasing. Therefore, based on logical extrapolation of observations of Western countries, the incidence of GEJAC will increase in Korea. However, the proportion of GEJAC among other upper gastrointestinal malignancies in Korea appears to be currently unchanged compared with that in the 1990s. Presently, there is a lack of epidemiologic studies on this issue in this region; therefore, more studies are needed to clarify the characteristics of these tumors and to improve clinical outcomes for patients with these tumors.

A retrospective study of 16 cats with intermediate- to high-grade alimentary lymphoma

  • Kwak, Dong-Hyuk;Cho, Mun-Ju;Park, Hyung-Jin;Song, Kun-Ho;Seo, Kyoung Won
    • Korean Journal of Veterinary Research
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    • v.61 no.1
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    • pp.8.1-8.10
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    • 2021
  • The purpose of this retrospective study was to describe cases of feline intermediateto high-grade alimentary lymphoma regarding signalment, clinical presentation, laboratory findings, response to therapy (modified 25-week University of Wisconsin-Madison [UW-25] vs. COP [cyclophosphamide, vincristine, prednisone]), toxicosis, and outcomes and to identify prognostic factors. Sixteen cats were treated with chemotherapy protocols. Response rates and survival did not differ statistically between the two protocols. The progression-free interval (PFI) and median survival time (MST) in cats achieving a response to therapy were longer than in those with no response [NR] (complete remission [CR] vs. partial remission [PR] vs. NR; PFI, 124 vs. 49 vs. 12 days, p < 0.001; MST, 361 vs. 118 vs. 16 days, p < 0.001). Clinical stage was another prognostic factor for PFI and MST. The PFI and MST in cats in stage I were longer than in those in other stages (PFI, 107 days vs. 30 days; MST, 193 days vs. 54 days). Hematologic and gastrointestinal toxicosis was mostly low grade. In comparing the modified UW-25 protocol with the COP protocol, there was not much difference in the number of neutropenic episodes and grade levels.

A Rare Case of Intestinal T-cell Lymphoma with Multiple Complications

  • Seung Yong Shin
    • Journal of Digestive Cancer Research
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    • v.11 no.2
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    • pp.114-118
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    • 2023
  • Intestinal T-cell lymphoma is a rare and aggressive form of non-Hodgkin lymphoma. Owing to its rarity and variable manifestations, intestinal T-cell lymphoma is usually diagnosed at an advanced stage. Therefore, it may be accompanied with serious complications at the time of diagnosis. Herein, I reports a case of intestinal T-cell lymphoma with multiple severe complications.

Effect of Bile juice on the Bioavailability and Pharmacokinetics of Acebutolol in Rabbits (토끼에서 체내담즙이 아세부톨롤의 생체이용률 및 체내동태에 미치는 영향)

  • 최준식
    • YAKHAK HOEJI
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    • v.46 no.1
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    • pp.47-51
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    • 2002
  • Although acebutolol (ABT) is almost completely absorbed in the gastrointestinal (Gl) tract, oral bioavailability of the drug is low due to extensive first-pass metabolism in the Gl tract and liver. In the present study, bioavailability and pharmacokinetics of ABT was studied in bile duct-bypassed rabbits after oral administration. For ABT the time to reach the plasma peak (T$_{max}$) and mean resident time (MRT) were increased by the treatment. For diacetolol (DAT), a metabolite of ABT area under the plasma concentration-time curve (AUC), T$_{max}$ and plasma half-life were increased by the treatment. These results indicate that oral bioavailability of ABT is associated with the enterohepatic recycling of bile juice components.nts.

Acupuncture and Moxiburstion Alleviates Chronic Postoperative Pain as a Comlication of Gastrointestinal Surgery: Apropos 8 Cases (침구치료를 통해 소화기계 수술 후 발생한 만성적 수술 후 통증이 호전된 환자 8례)

  • Choi, Jun-Yong;Kim, So-Yeon;Cho, Min-Kyoung;Kim, Do-Hyung;Park, Seung-Chan;Kwon, Jung-Nam;Hong, Jin-Woo;Lee, In;Park, Seong-Ha;Han, Chang-Woo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.26 no.2
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    • pp.206-211
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    • 2012
  • Here we described 8 patients treated with acupuncture and moxiburstion due to chronic postoperative pain as a comlication of gastrointestinal surgery. The patients were suffering from pain that continued for more than 6 months after laparotomy for gastric cancer (n=1), rectal cancer (n=2), cholangiocarcinoma (n=2), hepatocellular carcinoma (n=2) and ischemic colitis (n=1), respectively. Mean time elased from surgery were 31.25(${\pm}21.72$)months, pain grade on first visit by VAS(visual analogue scale, 0~10mm) was 3.75(${\pm}0.97$)point, and acupuncture and moxiburstion were performed 12.63(${\pm}5.74$)times during 5.5(${\pm}2.4$)weeks, on average. At the end of treatment, pain was decreased 2.75(${\pm}0.97$)point compared to first visit. Based on the that results, it is reasonable to assume that acupuncture and moxiburstion can be effective to persistent post-surgical pain after laparotomic gastrointestinal surgery, at least to some laparotomized patients.