• 대한한방소아과학회지
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• 제29권1호
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• pp.60-68
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• 2015

Objectives The purpose of this study is to establish relationship between functional gastrointestinal disorders in children and Temperament and Character using objective criteria and questionnaires. Methods This study surveyed 3-6 years old 130 children who were attending the kindergarten or daycare center in the vicinity of Gangdong from May 15th, 2014 to November 30th, 2014. The Korean-translated Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III (QPGS-Rome III) and The Junior Temperament and Character Inventory 3-6 (JTCI 3-6) questionnaires were used. Results 1. Between the groups, functional gastrointestinal disorder group scored significantly higher on NS, NS1, NS4, HA4, ST and ST1. 2. As the number of functional gastrointestinal disorders increase, the group scored higher on NS, NS1, NS4, HA4, ST and ST1. Conclusions This study showed functional gastrointestinal disorder group exhibited higher NS, NS1, NS4, HA4, ST and ST1 scores.

• 동의생리병리학회지
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• 제24권1호
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• pp.22-25
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• 2010

Hyangsapyeongwi-san has been used for various gastrointestinal diseases in Oriental medicine. Nevertheless, there is little known to scientific evidence for its efficacy and mechanism. This study was aimed to investigate effects of Hyangsapyeongwi-san in gastrointestinal diseases through the analysis of articles. A total of 15 articles were selected from PubMed, KTKP, and Weipu. The selected articles were analyzed according to three aspects of study types, target diseases and its efficacy, and results of clinical studies. Hyangsapyeongwi-san has positive effects in gastrointestinal disorders, such as prevent gastric mucosal injury, improve hyperacidity and dyspepsia, protect oxidative damage, and antitumor effects and enhance both cellular and humoral immunity. However, it proved insufficient to confirm its efficacy owing to lack of clinical studies of high quality. So, we need well designed studies to verify clinical efficacy of Hyangsapyeongwi-san hereafter.

• 동의생리병리학회지
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• 제20권5호
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• pp.1369-1373
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• 2006

This study was aimed to evaluate the effect of Herbal medicine on gastrointestinal symptoms. After the patient was treated with Banhabakchulchunma-tang, Samchulkunbi-tang and Geranil Herba, and the changes in gastrointestinal symptoms were evaluated for the treatment efficacy every five day. The symptoms improved significantly. Herbal medicine is useful for the treatment with gastrointestinal disturbance patient

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.1779-1782
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• 2012

Background & Objectives: In patients with gastric cancer, the most frequently reported family history of cancer also involves the stomach. The aim of this study was to assess the presence of gastric precancerous lesions in first-degree relatives of patients with gastric cancer and to compare the obtained results with those of individuals with no such family history. Methods: Between 2007 and 2009, 503 consecutive persons more than 30 years old were enrolled in the study covering siblings, parents or children of patients with confirmed adenocarcinoma of stomach. The control group was made up of 592 patients who were synchronously undergoing upper gastrointestinal endoscopy for evaluation of dyspepsia without gastric cancer or any family history. All subjects were endoscopically examined. Results: The overall prevalence of Helicobacter pylori was 77.7% in the cancer relatives and in 75.7% in the control group. Chronic gastritis was found in 90.4% vs. 81.1% (P<0.001). Regarding histological findings, 37(7.4%) of the study group had atrophy vs. 12(1.7%) in the control group (P<0.001), while no difference was observed for intestinal metaplasia (20.3%vs. 21.6%, P=0.58). Dysplasia were shown in 4% of cancer relatives but only 0.4% of the control group (P<0.001). There was no gender specificity. Conclusions: Findings of our study point to great importance of screening in relatives of gastric cancer patients in Iran.

• 대한한의학회지
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• 제25권1호
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• pp.198-204
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• 2004

Backgrounds & Methods : Asthma is considered to be chronic inflammatory disease characterized by airway hyperresponsiveness and pulmonary eosinophilia. Recently, there has been many researches about asthma. IBS(Irritable Bowel Syndrome), PUD(peptic Ulcer disease) and GERD(gastroesophageal reflux disease) are the most common diseases of the gastrointestinal tract. Recent studies suggest that IBS, PUD and GERD are associated with bronchial hyper-responsiveness and bronchial asthma might be more prevalent in IBS and GERD patients than in control subjects. In addition, there are many comments about the interrelationship between the gastrointestinal problem and asthma in the oriental medical books. Actually, many oriental medical doctors don$^{\circ}$Øt consider the gastrointestinal condition when they deal with the asthmatic patients these days. So, we assessed the prevalence of gastrointestinal symptoms and histories in a cohort of patients with asthmatic symptoms. We evaluated 128 outpatients with asthmatic symptoms(60 males and 68 females, aged 13-75). All subjects enrolled completed the GSRS(Gastrointestinal Symptom Rating Scale). GSRS is an interview based rating scale consisting of 15 items for assessment of gastrointestinal symptoms in IBS and PUD developed by Jan Svedlund. Results : The limit of total score of GSRS in asthmatic patients is zero to 30. The number of patients with no GI symptoms is 66(51.5%). The number of patients with GSRS>5 is 62(48.4%), GSRS>10 is 24(18.8%), GSRS>15 is 8(6.25%). The number of patients with history of gastritis is 54(42.2%), gastric ulcer is 13(10.2%), gastroptosis is 8(6.25%), IBS is 6(4.68%), others is 6(4.68%). Conclusions : This study suggests that patients with bronchial asthma have an significant prevalence of gastrointestinal symptoms. Additional studies are needed to find the mechanism of the association between gastrointestinal symptoms and asthma.

• 대한예방한의학회지
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• 제3권1호
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• pp.101-123
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• 1999

To investigate the documental records of the medi-alcohol theraphy on the Gastrointestinal disease, the 33 kinds of medical books editioned from the old to the present were used. the results were followed Many herbs used on the Gastrointestinal disease were sequently Atractylodis Macrocephalae Rhizoma, Zingiberis Rhizoma, Ginseng Radix. The herbs of invigorating and warming body, regulating the flow of qi etc. were many occupied(used) in treating the Gastrointestinal disease. In analyzing treatment symptom as medi-alcohol theraphy were sequently many used abdominal pain, inappetence, gastrointestinal cancer, indigestion, fatigue, vomiting, diarrhea, abdominal dropsy. The kinds of using medi-alcohol on the Gastrointestinal disease were totally 120 ones.

• 동의생리병리학회지
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• 제26권1호
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• pp.137-141
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• 2012

Although dysphagia and globus is a common comlication in Functional gastrointestinal disorder, there are few studies or reports about its treatment in oriental medicine. This study was to report the effect of Bokryungyeum-tang in Functional gastrointestinal disorder patients with dysphagia. Functional gastrointestinal disorder patients with dysphagia hospitalized in our hospital were treated by Bokryungyeum-tang every day. three times a day for two weeks. The patient showed constant improvement during the two weeks. Not only their objective measure, but also their subjective symptoms such as chest discomfort, insomnia, and depression improved too. This suggests that Bokryungyeum-tang is quite effective when treating functional gastrointestinal disorder patients with dysphagia.

• 임상간호연구
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• 제29권1호
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• pp.85-94
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• 2023

Purpose: The purpose of this study was to investigate the influencing factors of post-traumatic growth in patients with gastrointestinal cancer. Methods: A cross-sectional study was conducted, enrolling 120 patients with gastrointestinal cancer. Their general characteristics, disease-related characteristics, perceived illness intrusiveness, levels of optimism, social support, and post-traumatic growth were assessed through self-administered questionnaires. The collected data were analyzed using descriptive statistics, independent t-test, oneway ANOVA, Pearson's correlation, and multiple regression analysis. Results: The mean score of post-traumatic growth was 52.74 points(total score of 92 points). Among the subscales of post-traumatic growth, levels of the preciousness of life were the highest, and relating with others was the lowest. The post-traumatic growth was found to be significantly correlated with optimism (r=.48, p<.001), social support (r=.47, p<.001), and depression (r=-.37 p<.001). Factors associated with post-traumatic growth were optimism (β=.36, p<.001), social support (β=.31, p<.001), and depression (β=-.27, p<.001). Conclusion: Given that prevalence of gastrointestinal cancer is increasing in Korea, identifying general, psychological, and social factors affecting post-traumatic growth among this population will be helpful in clinical practice. Integrated strategies to increase optimism and social support and lower depression should be considered to improve the post-traumatic growth of patients with gastrointestinal cancer.

• 대한한방내과학회지
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• 제38권6호
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• pp.980-999
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• 2017

Objectives: This study aimed to evaluate the efficacy of Daegunjoong-tang for improvement of gastrointestinal motility after surgery due to gastrointestinal cancer by analyzing the existing clinical research. Methods: Clinical studies about Daegunjoong-tang for improvement of gastrointestinal motility after surgery due to gastrointestinal cancer were identified in a literature search using the search term "Daikenchuto AND cancer AND ileus." The studies were analyzed in terms of design, inclusion and exclusion of participants, intervention, control, outcomes, and results. Results: Nine articles were identified in the literature search. Four trials included colon cancer participants with colectomy, and three studies included gastric cancer with total gastrectomy. The intervention in each case was Daegunjoong-tang, and most interventions were made by a pharmaceutical company with a Good Manufacturing Practice facility. The most frequently used control was a placebo. The methods were diverse, including measuring gastrointestinal function, motility, quality of life, symptom scores with a numeric rating scale, and blood tests. Safety was investigated by recording adverse events. Conclusions: Some issues were discovered by reviewing the existing clinical research about Daegunjoong-tang for improvement of gastrointestinal motility after surgery for gastrointestinal cancer. These results will be utilized as evidence for using Daegunjoong-tang in clinical practice and designing a clinical trial for Korean patients.

• Clinical Endoscopy
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• 제57권1호
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• pp.73-81
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• 2024

Background/Aims: Upper gastrointestinal bleeding (UGIB) is a life-threatening condition that necessitates early identification and intervention and is associated with substantial morbidity, mortality, and socioeconomic burden. However, several diagnostic challenges remain regarding risk stratification and the optimal timing of endoscopy. The PillSense System is a noninvasive device developed to detect blood in patients with UGIB in real time. This study aimed to assess the safety and performance characteristics of PillSense using a simulated bleeding model. Methods: A preclinical study was performed using an in vivo porcine model (14 animals). Fourteen PillSense capsules were endoscopically placed in the stomach and blood was injected into the stomach to simulate bleeding. The safety and sensitivity of blood detection and pill excretion were also investigated. Results: All the sensors successfully detected the presence or absence of blood. The minimum threshold was 9% blood concentration, with additional detection of increasing concentrations of up to 22.5% blood. All the sensors passed naturally through the gastrointestinal tract. Conclusions: This study demonstrated the ability of the PillSense System sensor to detect UGIB across a wide range of blood concentrations. This ingestible device detects UGIB in real time and has the potential to be an effective tool to supplement the current standard of care. These favorable results will be further investigated in future clinical studies.