• Title/Summary/Keyword: gamma-irradiated

Search Result 1,184, Processing Time 0.026 seconds

Amentoflavone Acts as a Radioprotector for Irradiated v79 Cells by Regulating Reactive Oxygen Species (ROS), Cell Cycle and Mitochondrial Mass

  • Xu, Ping;Jiang, En-Jin;Wen, Si-Yuan;Lu, Dan-Dan
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.18
    • /
    • pp.7521-7526
    • /
    • 2014
  • Radioprotective effects of amentoflavone were investigated by examining cell viability, apoptosis, cell cycling concentrations of intracellular ROS (reactive oxygen species), and relative mitochondrial mass by flow cytometry after $^{60}Co$ irradiation. Pretreatment with amentoflavone 24 hours prior to 8 Gy $^{60}Co$ ${\gamma}$-ray irradiation significantly inhibited apoptosis, promoted the G2 phase, decreased the concentration of ROS and mitochondrial mass. These results collectively indicate that amentoflavone is an effective radioprotective agent.

Degardatrion of Cellulosic Fibers by Electron Beam Irradiation

  • Han, Sung-Ok;Seo, Yung-Bum;Lee, Chun-Han
    • Journal of Korea Technical Association of The Pulp and Paper Industry
    • /
    • v.39 no.5
    • /
    • pp.20-25
    • /
    • 2007
  • Henequen fibers were treated by electron beam irradiation and by NaOH to make surface modification for better bonding in the manufacture of biocomposite. Impurity removal and carbonyl group formation were noticed in the previous study by electron beam irradiation, but extensive cellulose degradation were also noticed. To evaluate the effects of electron beam irradiation on cellulosic fibers further, henequen fibers, cotton pulp, cotton fibers, and cellophane were irradiated by electron beam, and their changes of cellulose viscosity, chemical composition, and tensile strength were measured and analyzed.

LACTIC ACID DEHYDROGRENASE IN THE COBALT$Co^{60}$ IRRADIATED RAT INCISOR PULP (백서에 $Co^{60}$ 조사시 전치 치수내 LDH isoenzyme에 관한 연구)

  • Chung, Tai-Young;Chung, Ki-Kuen;Yi, Kui-Nyung;Choi, Kuen-Bae;Kim, Dong-Soon
    • The Journal of the Korean dental association
    • /
    • v.10 no.2
    • /
    • pp.97-107
    • /
    • 1972
  • 백서에 1000R의 $Co^{60}$-gamma선을 전신 조사 후 시간에 따른 LDH isoenzyme의 Pattern과 그의 활성도의 변화를 관찰한 바 다음과 같은 결론을 얻었다. 1. 조사후 72시간에 LDH-1와 LDH-4의 뚜렷한 Pattern을 나타내어, 이는 치수의 energy 대사가 염기성과 호기성 대사과정을 동시에 행함을 의미한다. 2. LDH의 총활성도는 조사후 24시간에 현저히 감소하였으나 72시간 후에는 거의 비조사군에 가까워졌다.

  • PDF

A Study on Sterilization of Medical Products by Gamma-irradiation. (Gamma선 조사에 의한 의류제품의 멸균연구)

  • 정해원;정문식;문석형
    • Journal of Environmental Health Sciences
    • /
    • v.5 no.1
    • /
    • pp.1-9
    • /
    • 1978
  • Biological safety, physico-chemical and microbiological experiments were carried out in order to study the possibility of radiation sterilization on medical products, such as polyethylene and polystyrene bottles, gauze sponges and surgical silk suture. Results are as follows: 1. Biological test on plastic samples as to acute systemic toxicity, eye irritation, skin irritation, pyrogen, haemolysis showed satisfactory results. But physico-chemically, the oxidizable matter, nonvolatile residues, residue on ignition seemed to be increased slightly in irradiated samples, though the experimental results were within the range of U.S.P. 19, N.F. and K.P. III. 2. After irradiation, both plastic and gauze sponges showed considerable decrease in pH. 3. Most medical products were sterilized by 1.5 Mard. For the sterilization of the suigical silk suture, 4.5 Mrad is required dul to its radiation resistant micro-organisms. 4. Biologically, total dose of 2.5 Mrad was safe enough to sterilize the medical products, and physico-chemically the results are acceptable according to U.S.P. 19 and K.P. III. However, better results may be expected when the quality of material and additives are improved.

  • PDF

Habituation of Escherichia coli O157:H7 in Alkali and Susceptibility of Causative Agents (알칼리조건에서 Escherichia coli 0157:H7의 적응 및 항균요법제에 대한 감수성)

  • 배종호
    • The Korean Journal of Food And Nutrition
    • /
    • v.12 no.6
    • /
    • pp.564-568
    • /
    • 1999
  • Habituation to alkali condition and susceptibility to antimicrobial agents were investigated to determine methods t inactivation Escherichia coli O157:H7 associated with food poisoning. The investigation showed that Escherichia coli O157:H7growth at pH 9.0 The susceptibilities of Escherichia coli O157:H7 to 13 drugs examined were found highest in regad to saicin and ceftriaxone and lowest in regard to erythromycin and josamycin. No significant changes in minimal inhibitory concen-tration(MIC) values of bactericidal effect was found when saicin and ceftriaxone were irradiated with doses of 5-100KGy.

  • PDF

Radiosterilization of Medical Products(II) (전이방사선을 이용한 의료제품 멸균연구 II)

  • 이강순;천기정;김기수
    • Korean Journal of Microbiology
    • /
    • v.13 no.2
    • /
    • pp.64-70
    • /
    • 1975
  • As a serial experiment of radiosterilization of medical products, we investigated the feasibility of using gamma ray to sterilize antibiotics, tetracycline HCl. Tetracycline HCl in aqueous solution and dried state irradiated with several dose levels was assayed for physico-chemical properties by checking UV absorption spectra, paper chromatogrph. IR spectra and NMR sepctra, and antibiotic activities by [means of agar plaque technique and tube $d_1$]ution method. In physico-chemical propertis and biological activities, the teracycline HCl in dried state remained radioresistant up to exposure of 10 Mrad, however, in aqueous solution, the dose of 300 Krad produced a significant inactivation. From the results of this study, radiosterilization of tetracycline HCl is more recommendable in the dried state than in aqueous solution.

  • PDF

Detection of Radiation Degradation of LDPE by ESR Spectroscopy (전자스핀공명을 이용한 저밀도 폴리에틸렌의 방사선 열화 검지)

  • Kim Ki-Yup;Lee Chung;Ryu Boo-Hyung
    • Journal of the Korean Society of Safety
    • /
    • v.20 no.1 s.69
    • /
    • pp.81-86
    • /
    • 2005
  • This study has investigated radiation degradation of low density polyethylene(LDPE). Samples were irradiated up to 800kGy using a $Co^{60}\;\gamma-ray$ at a dose rate of 5kGy/hr in the presence of air atmosphere at room temperature. After irradiation, storing for 2 weeks, free radical measurement of LDPE has established by electron spin resonance(ESR). ESR measurement showed that free radical concentration(FRC) was increased with radiation dose and decreased with the time. The radical types showed alkyl, allyl, and peroxy radical with the irradiation, these changed to peroxy radical with the time.

A Study on the Radiation-Induced Loss of Optical Fiber by ${\gamma}$-ray Irradiation (감마선 조사에 의한 광섬유의 전송손실 특성변화에 관한 연구)

  • 김웅기;이용범;이종민
    • Journal of the Korean Institute of Telematics and Electronics
    • /
    • v.27 no.4
    • /
    • pp.604-611
    • /
    • 1990
  • One of the confronting problems in using optical fibers under radiation environments is producing of color centers in optical materials due to nuclear radiation. These centers increase transmission loss by absorbing propagating light. In this study, the radiation effects on optical fiber are studied theoretically. Also, optical attenuation induced by \ulcorner-ray irradiation from Co**60 for single mode and multimode optical fibers is measured at the optical wavelength of 0.85\ulcorner and 1.3\ulcorner, and the results are analyzed. Gammaray is irradiated for 5hours at the rate of 300rads/min, which is corresponding to 90 krads of integrated dose. In case of multimode optical fibers, the induced loss at 0.85\ulcorner wavelength has been twice higher than that at 1.3\ulcorner. The loss in multimode fibers has been significantly larger by 7-20 times than that in single mode fibers, dependently on fiber materials at 1.3\ulcorner.

  • PDF

CURRENT STATUS OF INTEGRITY ASSESSMENT BY SIPPING SYSTEM OF SPENT FUEL BUNDLES IRRADIATED IN CANDU REACTOR

  • Park, Jong-Youl;Shim, Moon-Soo;Lee, Jong-Hyeon
    • Nuclear Engineering and Technology
    • /
    • v.46 no.6
    • /
    • pp.875-882
    • /
    • 2014
  • In terms of safety and the efficient management of spent fuel storage, detecting failed fuel is one of the most important tasks in a CANada Deuterium Uranium (CANDU) reactor operation. It has been successfully demonstrated that in a CANDU reactor, on-power failed fuel detection and location systems, along with alarm area gamma monitors, can detect and locate defective and suspect fuel bundles before discharging them from the reactor to the spent fuel storage bay. In the reception bay, however, only visual inspection has been used to identify suspect bundles. Gaseous fission product and delayed neutron monitoring systems cannot precisely distinguish failed fuel elements from each fuel bundle. This study reports the use of a sipping system in a CANDU reactor for the integrity assessment of spent fuel bundles. The integrity assessment of spent fuel bundles using this sipping system has shown promise as a nondestructive test for detecting a defective fuel bundle in a CANDU reactor.

Aldehydes in $\gamma$-irradiated Solid Starch

  • Kim, Chul;Ohm, Young-Ran
    • Nuclear Engineering and Technology
    • /
    • v.4 no.1
    • /
    • pp.35-38
    • /
    • 1972
  • A study of the radiation-induced formation of carbonyl compounds in solid starch by means of precipitation with 2, 4-dinitrophenylhydrazine and subsequent analysis of the hydrazones by gas chromatograph has been performed. formation of carbonyl groups was found to increase linearly with increasing doses up to about 2$\times$10$^{21}$ eV/g. Generally, at least 5 different peaks can be detected including formaldehyde and acetaldehyde.

  • PDF