• 제목/요약/키워드: functional form group

검색결과 183건 처리시간 0.024초

Functional Roles of the Aromatic Residues in the Stabilization of the [$Fe_4S_4$] Cluster in the Iro Protein from Acidithiobacillus ferrooxidans

  • Zeng, Jia;Liu, Qing;Zhang, Xiaojian;Mo, Hongyu;Wang, Yiping;Chen, Qian;Liu, Yuandong
    • Journal of Microbiology and Biotechnology
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    • 제20권2호
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    • pp.294-300
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    • 2010
  • The Iro protein is a member of the HiPIP family with the [$Fe_4S_4$] cluster for electron transfer. Many reports proposed that the conserved aromatic residues might be responsible for the stability of the iron-sulfur cluster in HiPIP. In this study, Tyr10 was found to be a critical residue for the stability of the [$Fe_4S_4$] cluster, according to site-directed mutagenesis results. Tyr10, Phe26, and Phe48 were essential for the stability of the [$Fe_4S_4$] cluster under acidic condition. Trp44 was not involved in the stability of the [$Fe_4S_4$] cluster. Molecular structure modeling for the mutant Tyr10 proteins revealed that the aromatic group of Tyr10 may form a hydrophobic barrier to protect the [$Fe_4S_4$] cluster from solvent.

한국 남서해안 진도군 금갑의 해조상 및 군집구조의 계절 변화 (Seasonal Variability of Marine Algal Flora and Community Structure at Gumgap, Jindo, on the Southwestern Coast of Korea)

  • 유현일;허진석;최한길
    • 수산해양교육연구
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    • 제27권1호
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    • pp.300-307
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    • 2015
  • Seasonal variation in marine macroalgal community structure was examined at the intertidal zones of Geumgap, Jindo, Korea, from October 2013 to August 2014. In total, 56 macroalgal species were identified, including 9 green, 12 brown, and 35 red algae. Annual seaweed biomass was 548.96 g wet wt. /$m^2$ with seasonal range between 371.08 g wet wt. /$m^2$ at summer and 32.91 g wet wt. /$m^2$ at winter. The dominant seaweed in terms of biomass was Sargassum thunbergii and subdominant species were Gelidium elegans, Sargassum fusiforme, and Ishige okamurae. The vertical distribution of seaweeds from the upper to lower intertidal zones was Gloiopeltis spp., Ulva spp.- S. thunbergii, S. fusiforme, Ishige okamurae - S. thunbergii, S. fusiforme, G. elegans. Annual seaweed coverage, richness index (R), evenness index (J'), and diversity index (H') values were 27.95%, 6.10, 0.38, and 1.38, respectively. Coarsely branched form was the most dominant functional group in terms of species number and biomass among benthic macroalgal species.

DEMS와 H-terminated Si (001) 표면의 상호작용: 제일원리연구 (Interaction of DEMS with H-terminated Si (001) Surface: A First Principles Study)

  • 김대현;김대희;박소연;서화일;이도형;김영철
    • 한국세라믹학회지
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    • 제46권4호
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    • pp.425-428
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    • 2009
  • We performed a density functional theory study to investigate the interaction of DEMS (diethoxymethylsilane) with the H-terminated Si (001) surface. The optimum structure of DEMS was first calculated by a first principles study. The dissociation probability of the O-C bond of DEMS was higher than the other seven bonds based on the bond energy calculation. When the fragmented DEMS groups reacted with the H-terminated Si (001) surface, it was the most favorable among the eight reactions to form a bond between the Si atom on the surface and the O atom of a fragmented DEMS group (($C_2H_5O$)Si($CH_3$)(H)-O-) by forming a $C_2H_6$ as by-product.

코로나 방전처리에 의한 폴리에스테르 및 P/C 혼방직물의 복합기능화 가공(I) -난연 및 위생가공- (Multi-Functional Finish of Polyester and P/C blend Fabrics by Corona Discharge(I) -Flame-Retardant and Sanitary Finish-)

  • Lee, Bang One;Pak, Pyong Ki;Lee, Hyun Ja;Lee, Hwa Sun
    • 한국염색가공학회지
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    • 제9권2호
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    • pp.1-9
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    • 1997
  • This paper was carried out to introduce flame retardant and antibiotic properties to polyester(PET) and polyester/cotton(P/C) blend fabrics. PET and P/C blend fabrics were treated by a paddry-cure method in the aqueous solutions of the finishing agents(JA 6034, JA 6050, DC-5700). The corona discharge technique was applied to increase the polar group of the polymer surface. The characteristics of the treated fabric were investigated by means of scanning electron microscope (SEM) and electron spectroscopy for chemical analysis(ESCA), and water penetration time, limiting Oxygen index(LOI), and K/S value were also measured. Wettability of the fabrics was increased considerably with the corona discharge treatment. ESCA was used to elucidate the surface chemical composition of the fabrics treated with the corona discharge. Relative Ols intensity increased and oxygen was incorporated in the form of -C-O-, -C=O, and O=C-O on the polymer surface. The current study indicated that corona discharge treatment was effective for modifying the polymer surface.

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Mechanical and electrical properties of cement paste incorporated with pitch-based carbon fiber

  • Rhee, Inkyu;Kim, Jin Hee;Park, Sang Hee;Lee, Sungho;Ryu, Bong Ryeul;Kim, Yoong Ahm
    • Carbon letters
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    • 제23권
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    • pp.22-29
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    • 2017
  • The compressive strength and electrical resistance of pitch-based carbon fiber (CF) in cementitious materials are explored to determine the feasibility of its use as a functional material in construction. The most widely used CFs are manufactured from polyacrylonitrile (PAN-based CF). Alternatively, short CFs are obtained in an economical way using pitch as a precursor in a melt-blown process (pitch-based CF), which is cheaper and more eco-friendly method because this pitch-based CF is basically recycled from petroleum residue. In the construction field, PAN-based CFs in the form of fabric are used for rehabilitation purposes to reinforce concrete slabs and piers because of their high mechanical properties. However, studies have revealed that construction materials with pitch-based CF are not popular. This study explores the compressive strength and electrical resistances of a cement paste prism using pitch-based CF.

슈퍼스칼라 구조를 갖지 않는 고성능 Stream Processor 설계 (A Design of a High Performance Stream Processor without Superscalar Architecture)

  • 이관호;김치용
    • 전기전자학회논문지
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    • 제21권1호
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    • pp.77-80
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    • 2017
  • 본 논문에서는 기존의 superscalar GP-GPU 구조와 달리 superscalar issue를 제거하여 GP-GPU성능을 향상하는 방법을 제안한다. superscalar issue를 제거하기 위해 stream processor의 구조를 단순화했다. stream processor의 구조가 단순화 됨에 따라 하드웨어의 크기를 크게 늘리지 않고 thread 개 수가 늘려 성능을 개선하였다. thread 개수가 늘어남에 따라 thread의 묶음인 warp을 관리하는 warp scheduler 구조를 새롭게 제안하였다. 제안하는 warp scheduler는 superscalar issue가 제거 되어 있기 때문에 warp 활성화 정보를 통해 라운드 로빈 스케쥴링을 통해 활성화 된 warp에게 명령어를 전달한다. 성능 비교는 가우시안 필터링 연산을 사용하였으며 기존의 GP-GPU의 비해 7.89배의 성능향상을 보였다.

언택트 커뮤니케이션 지원환경으로써 가상세계 - 메타버스를 이용한 게임 유저 커뮤니티 형성의 가능성과 과제 - (The virtual world as a supportive environment for intact communication. -The possibility and task of forming a game user community using a metabus. -)

  • 김덕민;김수동;석현선;배신훈;정형원
    • 통합자연과학논문집
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    • 제15권1호
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    • pp.37-48
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    • 2022
  • Metabus, a three-dimensional virtual environment for digital communication, has gained a lot of attention recently. Even so, there are still many unanswered questions about the user's consciousness and behavior. A difference in nature from conventional digital communication is also unclear. This paper aims to study Metabus on a hypothetical premise by organizing the possibility of Metabus for communication activation based on a research project aimed at using Metabus to support the formation of a community of school dormitories and studio rental residents. After reviewing the establishment process and application cases of Metabus, we focus on the character (avatar) used as the user's alter ego within the metabus, which will allow customization of both form and content different from text-based communication. The "physicality" and the "spatiality" of the metaverse and the "immersion" they bring are among the most important, functional innovations. Based on this summary, a case of using metabuses will be reviewed to describe the research plan aimed at supporting community formation.

악관절 강직증에 관한 임상적 연구 (CLINICAL STUDY OF TEMPOROMANDIBULAR JOINT ANKYLOSIS)

  • 송민석;민병일
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제17권1호
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    • pp.60-72
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    • 1995
  • Temporomandibular joint ankylosis is the movemental obstacle of mandible which depend on proliferation of bony or fibrous tissue in temporomandibular joint structure by various causes. In order to treat this, various surgical methods have been performed, but no operative methods have been produced consistently successful results. This research has been performed to the patients who had been operated due to temporomandibular joint ankylosis by studying classification, cause, onset, duration, anesthesia and treatment method, symptom, change of mouth opening, complication through medical record, X-ray, follow-up for being a help to proper selection of treatment method and evaluation of prognosis. The author obtained the following results by analyzing 44 cases among patients who had been operated due to temporomandibular joint ankylosis during 8 year hospitalization from 1986 to 1993 in Dept. of Oral & Maxillofacial Surgery of Seoul National University Hospital. 1. The occurrence was in the order of below 10, 20's, 10's, 30's. The average of occurrence was 12.95. Illness period was 50.0% within 10 years and 50% beyond 10 years. The average period of illness was 13.33 years. 2. Trauma occupied 54.5% of causes and inflammation occupied 45.5%. Men had more occurrences due to trauma and there was no difference in case of inflammation. 3. In nasotracheal intubations for general anesthesia, the cases of using fiberoptic laryngoscope occupied 40.9%, direct or blind nasotracheal intubation occupied 40.9% and the cases of using tracheostomy occupied 18.2%. 4. In operative approaching methods, submandibular & preauricular approach were mainly applied, and in operative methods, high condylectomy(Group I) occupied 11.4%, arthroplasty without interpositional material following condylectomy or gap ostectomy(Group II) occupied 11.4%, with interpositional material following high condylectomy (Group III) occupied 40.9%, and using condylar reconstruction following condylectomy or gap ostectomy(Group IV) occupied 36.6%. 5. In change of mouth opening reformed after surgery, Group III showed the best result of average 23.5mm, Group IV showed 16.3mm, Group I showed 14.9mm and Group II showed 10.2mm of reformation. Summarizing the results as written above, it is considered that early treatment is important as soon as possible in Temporomandibular joint ankylosis. It is recommended in surgical method what can lead to postoperative early movement maintaining anatomaical & functional form, and then the development of various surgical methods will be requested.

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아세클로페낙의 경피 제제설계 및 피부투과 특성 (Formulation and Skin Penetration Characteristics of Aceclofenac Plaster for Transdermal Delivery)

  • 정종근;이민석;박정화;이장원;김하형;최영욱;이광표
    • Journal of Pharmaceutical Investigation
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    • 제29권1호
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    • pp.29-36
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    • 1999
  • Aceclofenac is an non-steroidal antiinflammatory drug which has been used in the treatment of rheumatoidal rthritis and osteo-arthritis. In order to decrease the gastric ulcerogenic effects and contol the plasma level of aceclofenac, we have developed the transdermal delivery system of aceclofenac plaster, which were formulated employing matrix polymers of acrylates and penetration-enhancers such as $Lauroglycol^{\circledR}$, $Transcutol^{\circledR}$, oleic acid and linoleic acid. Using Franz diffusion cells mounted with a rat skin, transdermal penetration characteristics of the formulations were evaluated by the HPLC assay of aceclofenac and diclofenac, an active metabolite, in the receptor compartment of pH 7.2 phosphate buffered solution. Skin penetration was increased when the content of aceclofenac increased, showing the flux $(J,\;{\mu}g/cm^2/hr)$ of 0.37 and 2.50 for 2% and 6.75% of the content, respectively. The flux$(J,\;{\mu}g/cm^2/hr)$ from plasters made of $Durotak^{\circledR}$ 87-2074, $Durotak^{\circledR}$ 87-2510 and $Durotak^{\circledR}$ 87-2097 were 2.50, 2.77 and 4.39, respectively. $Durotak^{\circledR}$ 87-2074 showed the lowest penetration due to the carboxylic acid group in the polymer, which might form a strong hydrogen bonding with a secondary amine of aceclofenac. Although both $Durotak^{\circledR}$ 87-2510 and $Durotak^{\circledR}$ 87-2097 are amine-resistant adhesives, $Durotak^{\circledR}$ 872510 showed lower penetration than $Durotak^{\circledR}$ 87-2097 because of the hydroxyl group in $Durotak^{\circledR}$ 87-2510, which might form a weak hydrogen bonding with aceclofenac. These results reveal that the functional group in acrylic polymers would greatly affect the release of aceclofenac from the matrix, which is the rate-limiting step in the penetration of aceclofenac through rat skins. The penetration of aceclofenac from plasters using different penetration-enhancers increased in the following order: Transcutol < linoleic acid < oleic acid. And the flux from the plasters containing oleic acid as a penetrationenhancer was 2.22 times greater than that of creams, which suggest that a newly deveolped aceclofenac plaster could be used in the treatment of rheumatoidal arthritis and osteo-arthritis as an advanced transdermal delivery system.

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부산 이기대 지역의 해조상 및 군집구조 (Marine Algal Flora and Community Structure of Igidea Area in Busan, Korea)

  • 신봉균;권천중;이석모;최창근
    • 해양환경안전학회지
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    • 제20권2호
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    • pp.121-129
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    • 2014
  • 우리나라 동남해 연안 해역에 위치한 이기대 지역에서 2010년 5월부터 2011년 2월까지 계절별로 해조상 및 군집구조에 관한 연구를 수행하였다. 조사기간 동안 녹조류 9종, 갈조류 14종, 홍조류 43을 포함한 총 66종이 동정되었으며, 16종의 해조류는 조사지역에서 연중 출현하였다. 계절별 평균 현존량은 봄 $123.6g{\cdot}m^{-2}$, 여름 $2,061.6g{\cdot}m^{-2}$, 가을 $412.0g{\cdot}m^{-2}$, 겨울 $678.9g{\cdot}m^{-2}$로 나타났다. 종조성의 차이는 주변의 오염원이 존재하지 않는 정점 3과 4에 비하여 주변 하천의 영향을 받는 정점 1로 갈수록 종조성이 상대적으로 낮은 경향을 보였는데 이는 주변의 용호천, 대연천, 남부하수처리장 방류수에 의한 영향으로 판단되었다. 해조군집의 생태적 특성을 판단할 수 있는 R/P, C/P, (R+C)/P 값은 각각 3.07, 0.64, 3.71로 나타났으며, 해조류의 외부형태와 내부구조 등에 따라 구분되는 6가지 기능형군에 따른 분류결과는 성긴분기형 39.39 %, 엽상형 30.30 %, 다육질형 13.64 %, 사상형 12.12 %, 각상형 3.03 %, 유절산호말형 1.52 %으로 나타났다. 한편, 이기대 지역의 해조류 개체수는 1996년부터 1997년에 96종, 2010년부터 2011년에 66종으로 감소된 것을 확인하였다. 이는 주변하천과 하수처리장의 방류수 등에 의한 영향으로 판단된다. 결론적으로 대도시 인근 연안의 해조군락 보호 및 육성을 위하여 연안역에 유입되는 오하수의 처리 및 해조장 복원과 같은 적극적인 해양환경 유지관리방법이 체계적으로 추진되어야 할 것이다.