• Title/Summary/Keyword: functional effect

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Evaluation of Biological Activities of Invasive Alien Plants for Development of Functional Biomaterials

  • So Jin Kim;Su Hyeong Heo;Min Gun Kim;Kyung Hwan Boo;Chang Sook Kim
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2022.09a
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    • pp.112-112
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    • 2022
  • This study aims to confirm the possibility of using the invasive alien plants in Jeju as a functional biomaterial. To achieve this purpose, 70% ethanol extract and solvent fractions were prepared for five invasive alien plants (Hypochaeris radicata, Rumex acetosella, Humulus japonicus Siebold & Zucc., Solanum viarum, Lactuca scariolar) and their antioxidant, antibacterial anti-inflammatory and anti-obesity effects were investigated. The DPPH radical scavenging activity of ethanol extract from invasive alien plants was shown in the order of Rumex acetosella > Hypochaeris radicata > Humulus japonicus. Antimicrobial activity of ethanol extract against food poisoning bacteria (4 species) and oral cavity-induced microorganisms (6 species) was measured. As a result, the extract of Humulus japonicus showed high antibacterial effects against food poisoning bacteria (E. coli, V. parahaemolyticus) and oral microbes (L. casei, S. epidermidis, E. faecalis). In LPS-induced RAW 264.7 cells, the anti-inflammatory effect of ethanol extract from invasive alien plants was investigated. As a result, the NO production inhibition activity was highest in the Rumex acetosella and the Humulus japonicus Siebold & Zucc. ethanol extract, and the NO production inhibition activity was concentration-dependent. In addition, the Rumex acetosella and the Humulus japonicus Siebold & Zucc. ethanol extract showed a concentration-dependent inhibitory effect on cytokine (IL-6) production. These extracts also showed inhibitory activity of COX-2, an inflammatory protein. This suggests that NO production inhibition activity by the extract of invasive alien plants is the result of inhibition of iNOS and COX-2 expression. Currently, organic solvent fractions of crude extract are manufactured and the investigation of active ingredients is continuing along with evaluation of biological activity such as anti-inflammatory. These results are expected to be a major data for the study on the separation and utilization of active ingredients with antioxidant, antibacterial and anti-inflammatory effects using foreign plant crude extract and solvent fractions, and are highly likely to be applied to the development of functional food and cosmetics materials.

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Biological properties of fermented milk with fortified whey protein

  • Ki Whan Kim;Seok Han Ra;Gereltuya Renchinkhand;Woo Jin Ki;Myoung Soo Nam;Woan Sub Kim
    • Korean Journal of Agricultural Science
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    • v.50 no.2
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    • pp.281-294
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    • 2023
  • As a byproduct obtained from cheese manufacture, whey protein was developed as a functional food that contains multi-functional proteins. In this study, the biochemical activity of fermented milk prepared by fortifying whey protein with excellent physiological activity was investigated. Immunoglobulin (IgG) content was higher in 10% fortified whey protein fermented milk than in the control. The viable cell counts were 20% higher in the fermented milk with 10% fortified whey protein than in the control group. The antibacterial effect of 10% fortified whey protein fermented milk compared to the control group was shown to be effective against four pathogenic microorganisms, Escherichia coli (KCTC1039), Pseudomonas aeruginosa 530, Salmonela Typhimurium (KCTC3216), and Staphylococcus aureus (KCTC1621). The antioxidant effect by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities wasincreased two-fold in 10% fortified whey protein fermented milk compared to the control. The 10% fortified whey protein fermented milk inhibited the expression of the inflammatory cytokines (interleukin [IL]-6, tumor necrosis factor [TNF]-α, and induced nitric oxide synthase [iNOS]) in a concentration-dependent manner. In a piglets feeding test, the weight gain with 10% fortified whey protein fermented milk was increased by 18% compared to the control group, and no diarrhea symptoms appeared. Our results clearly demonstrated that 10% fortified whey protein fermented milk could be a useful functional ingredient for improving health.

Effect of Functionalized BR Content on the Wear Particulate Matters and Physical Properties in TBR Tire Tread Compounds

  • Junhwan Jeong;Sanghoon Song;Jin Uk Ha;Daedong Park;Jaeyun Kim;Yeongmin Jung;Donghyuk Kim;Kiwon Hwang;Sungwook Chung;Wonho Kim
    • Elastomers and Composites
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    • v.59 no.2
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    • pp.64-72
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    • 2024
  • As air pollution continues to increase owing to increasing traffic centered in urban areas, the tire industry is researching methods to reduce particulate matter. In this study, functionalized lithium butadiene rubber (F-LiBR) was applied to a natural rubber (NR)/butadiene rubber (BR) blend compound often used in truck bus radial (TBR) tire treads. The effect of the functional group that can react with carbon black (CB) in BR was investigated in terms of the dispersion of CB and the compound performance, including the generation of particulate matter. Compounds that were substituted with F-LiBR exhibited enhanced interaction with CB, resulting in excellent filler dispersion. Although F-LiBR exhibited lower crosslinking density and inferior abrasion resistance due to its high vinyl content, the compound with 30 phr of F-LiBR was advantageous in terms of its rolling resistance due to the excellent filler dispersion, which was also effective in reducing the amount of generated particulate matter (up to 56% reduction for PM2.5, and 67% reduction for PM10). The results confirmed the benefits of the introduction of functional groups into TBR tire tread compounds, which can aid in improving the fuel efficiency and reducing particulate matter generation.

The Effect of Task-oriented Training on Mobility Function, Postural Stability in Children with Cerebral Palsy

  • Kim, Ji-Hye;Choi, Young-Eun
    • Journal of the Korean Society of Physical Medicine
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    • v.12 no.3
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    • pp.79-84
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    • 2017
  • PURPOSE: The purpose of this study is to examine how task-oriented training focused on lower extremity strengthening can affect mobility function and postural stability. METHODS: The study's subjects included 10 children with cerebral palsy: 7 girls and 3 boys between the ages of 4 and 9 whose Gross Motor Functional Classification System (GMFCS) level was I or II. Their functional mobility was gauged using the Gross Motor Function Measurement (GMFM), and their postural stability was evaluated using a force platform. Participants received task-oriented training focused on lower extremity strengthening for 5 weeks. The study used a paired t-test to investigate the difference in mobility function and postural stability of children with cerebral palsy before and after the lower extremity strengthening exercise. RESULTS: The GMFM dimensions D (standing) (p<.02) and E (walking) (p<.001) improved significantly between the pre-test and post-test. A significant increase in the posturographic center of pressure (CoP) shift and surface area of the CoP were found overall between the pre-test and post-test (p<.001). CONCLUSION: The present study provides evidence that an 8-week task-oriented training focused on strengthening the lower extremities is an effective and feasible strategy for improving the mobility function and postural stability of children with cerebral palsy.

The Effects of High Intensity Laser Therapy on Pain and Function of Patients with Frozen Shoulder

  • Jeon, Chun-Bae;Choi, Seok-Joo;Oh, Hyun-Ju;Jeong, Mu-Geun;Lee, Kwan-Sub
    • The Journal of Korean Physical Therapy
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    • v.29 no.4
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    • pp.207-210
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    • 2017
  • Purpose: This study was to identify the effectiveness of high-intensity laser therapy on pain and function of a frozen shoulder. Methods: Thirty patients were assigned to two groups: the experimental group (n=15) and the control group (n=15). Both groups received traditional therapy for 4 weeks, 3 days a week. The experimental group, however, received an additional high intensity laser therapy. Pain was measured using the visual analogue scale (VAS). The functional ability was measured using the patient specific functional scale (PSFS). A paired t-test was used to determine any differences before and after the treatment, and an independent t-test was used to determine any differences between treatment groups. Results: Both groups showed a statistically significant difference for VAS and PSFS score (p<0.05). In comparison between two groups, more experimental group than control group statistically significant difference (p<0.05). Conclusion: There seems to be a positive effect on pain and function of frozen shoulder from using high intensity laser therapy.

The Characteristics of Sponge Cake with Moringa Powder (모링가 분말을 첨가한 스펀지케이크의 품질특성)

  • Choi, Hyoung-il
    • Culinary science and hospitality research
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    • v.24 no.3
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    • pp.188-195
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    • 2018
  • The objective of this study was to evaluate the quality characteristics of moringa powder enrichment in sponge cake. The developed product can be a promising inclusion in the functional foods. Moringa powder was added to sponge cake batter (in the ratios of 0, 3, 6, 9, 12% of the total flour), called MP3, MP6, MP9, and MP12 respectively. The effect of moringa supplementation on physical, chemical and sensory quality of cakes were evaluated and analyzed statistically using SPSS program. The pH of cake was decreased as the concentration of moringa powder added. The specific volume of cake samples decreased with increasing levels of moringa powder in the formulation. Colour measurements showed that lightness and yellowness were decreased with an increased level of moringa powder. But redness result revealed and increasing in redeness with the increasing morigna powder level, compared to the control sample. The results of texture profile analysis showed hardness, springness, cohesiveness of the moringa cake that were higher than control sample. In sensory evaluation, MP3 was selected as the most acceptable sample. In the conclusion, moringa powder was incorporated in the formulation to enrich sponge cakes and was suggested for development of functional foods.

Effects of Active Vibration Exercise on Trunk Muscle Activity, Balance, and Activities of Daily Living in Patients with Chronic Stroke

  • Lee, Dong-Kyu;Kim, Eun-Kyung
    • The Journal of Korean Physical Therapy
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    • v.30 no.4
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    • pp.146-150
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    • 2018
  • Purpose: This study aimed to investigate the effect of active vibration exercise on trunk muscle activity, balance, and activities of daily living in patients with chronic stroke. Methods: Twenty-four patients with chronic stroke were randomly assigned to an experimental (n=12) or a control (n=12) group. The experimental group performed an active vibration exercise workout for 20 minutes a day five times a week for 4 weeks using a flexi-bar. Trunk muscle activity was measured using surface electromyography. Balance was measured using the Berg balance scale. Activities of daily living were measured using the functional independence measure. Results: The intragroup comparison showed significant differences in the rectus abdominis, internal oblique, and external oblique muscle activity values, Berg balance scale score, and functional independence measurement values in the experimental group. The intergroup comparison showed that differences in the rectus abdominis and internal oblique external oblique muscle values, Berg balance scale score, and functional independence measurement value for the experimental group were significantly related to those in the control group. Conclusion: Based on these results, this study proved that the active vibration exercise effectively improved trunk muscle activity, balance, and activities of daily living in patients with chronic stroke.

Study of Medicinal Herbs for Applications in Functional Foods -Antifatigue Effects and Safety Evaluation of Leaf and Stem Extract of the Panax Ginseng- (가능성 식품으로의 활용을 위한 한약자원에 관한 연구 -인삼잎과 줄기 혼합 추출액의 항피로 효과 및 안전성 평가-)

  • Han Jong Hyun;Park Sung Hye
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.4
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    • pp.1134-1139
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    • 2004
  • This study was conducted to investigate the application possibility of leaf and stem extract(LSE) from the mixture of leaf and stem of ginseng radix(Panax Ginseng CA Meyer). This study measured antifatigue effects by rota-rod test and swimming test. Also we examined the cell toxicity in normal liver and kidney cells, and acute toxicity in mice. Dropping times of LSE treated group decreased about 39-83% compared to the control group according to supplementation intake levels. Swimming time in LSE treated group increased compared to the control group at short and long supplementation. Negative effects were not found from the results of the cell toxicity. Also acute toxicity not shown. These results imply that the leaf and stem of ginseng radix could be used as possible food resources and functional food material and feed stuff.

Effects of Pain, Sleep Disturbance, and Fatigue on the Quality of Life in Patients with Pancreatic Cancer Undergoing Chemotherapy (항암화학요법을 받는 췌장암 환자의 통증, 수면장애, 피로가 삶의 질에 미치는 영향)

  • Kim, Gyung-Duck;Jang, Hyun-Jin
    • Asian Oncology Nursing
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    • v.12 no.2
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    • pp.117-124
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    • 2012
  • Purpose: The purpose of this study was to assess pain, sleep disturbance, fatigue, and the quality of life and to identify the impact of pain, sleep disturbance and fatigue on the quality of life in patients with pancreatic cancer undergoing chemotherapy. Methods: Data were collected from June to July, 2010. Participants were recruited from Y university hospital in Seoul. Research instruments included numeric rating scale for pain, Functional Assessment Chronic Illness Therapy-Functional Well-Being (FACIT-FWB): General Factor 5 (GF5) for sleep disturbance, Functional Assessment of Cancer Therapy-General (FACT-G) for quality of life, and FACT-Fatigue for fatigue. Results: The quality of life for cancer patients had a significant relationship with pain, sleep disturbance, and fatigue. The significant factors influencing quality of life were pain, sleep disturbance, and fatigue that explained 52.6% of the variance. Conclusion: Patients with pancreatic cancer undergoing chemotherapy experienced pain, fatigue, and sleep disturbance which led to a negative effect on quality of life. The results suggest that intervention program to improve quality of life could reduce pain, fatigue, and sleep disturbance of pancreatic cancer patients undergoing chemotherapy.

Functional Properties of Cholesterol-removed Compound Whipping Cream by Palm Oil

  • Shim, S.Y.;Ahn, J.;Kwak, H.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.6
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    • pp.857-862
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    • 2004
  • The present study was carried out to examine the changes in functional properties of cholesterol-removed compound whipping cream made by $\beta$-CD treated cream and palm oil. Six different ratios of cream to palm oil (10:0 as control, 9:1, 8:2, 7:3, 6:4, and 5:5, v/v) were tested. The overrun percentage increased with an increased amount of palm oil. When the ratio of cream to palm oil was 10:0 (control), the overrun was 130%, which was significantly lower than other ratios reached to 150%. Foam instability was measured as 3.1 ml defoamed cream in control, however, the value of foam instability decreased with an increase of palm oil addition. The TBA value of cholesterol-removed compound whipping cream increased from 0.08 to 0.13 with no addition of palm oil during 4 wk storage. When the ratio of cream to palm oil was 5:5, TBA value increased dramatically at 3 wk and thereafter. Among sensory characteristics, texture value increased with higher amount of palm oil, however, flavor and overall preferences were opposite. Above results indicated that partial substitution of palm oil in manufacture of cholesterol-removed compound whipping cream resulted in a stable foam development with little adverse effect on flavor and lipid oxidation during storage. The present study showed a possible application in manufacture of cholesterol-removed compound whipping cream, which may be effective in other foods.