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Biomarkers associated with periodontitis and peri-implantitis: a systematic review

  • Kalsi, Amardip Singh;Moreno, Federico;Petridis, Haralampos
    • Journal of Periodontal and Implant Science
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    • 제51권1호
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    • pp.3-17
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    • 2021
  • Purpose: The pathology of peri-implantitis is still not fully understood and there have been recent challenges to the consensus on its aetiology and pathology, especially in comparison with periodontitis. The assessment of biomarkers allows a comparison of the pathology of these diseases. The aim of this systematic review was to answer the research question: "Is there a difference in the biomarkers associated with peri-implantitis compared with periodontitis in adult humans?" Methods: Electronic databases were searched and screened, and a manual search was also undertaken. The inclusion criteria were adults with peri-implantitis who had been compared to adults with periodontitis with the outcome of biomarkers assessed via biopsies or crevicular fluid samples in primary or secondary care settings, as recorded in case-control, case series and retrospective, prospective and cross-sectional observational studies. Two reviewers independently screened titles and abstracts and assessed full text articles for eligibility and inclusion. Both reviewers independently extracted data and assessed risk of bias. Differences in biomarker levels were the primary outcome and a narrative review was undertaken due to the heterogeneity of studies. Results: In total, 2,374 articles were identified in the search, of which 111 full-text articles were assessed for eligibility and 13 were included in the qualitative synthesis. Five of the 13 included studies were deemed to be at high risk of bias, with the others having moderate risk. All studies were cross-sectional and performed at university hospitals. Nine of the 13 included studies found significant differences in the levels of biomarkers or their ratios between periimplantitis and periodontitis. Four of the studies found no significant differences. Conclusions: Within the limitations of the included studies, it appears that there may be a difference in biomarker levels and ratios between peri-implantitis and periodontitis, suggesting that these disease processes are somewhat distinct.

CD-ROM을 활용한 의학정보봉사기능의 제고방안에 관한 연구 (A Study on the Enhancement of Medical Information Service Functions by the Utilization of CD-ROM)

  • 윤희윤
    • 한국문헌정보학회지
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    • 제27권
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    • pp.183-214
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    • 1994
  • The purpose of this study is to suggest the schemes to enhance information service functions by the utilization of CD-ROM in medical school libraries. The results of the study are summarized as follows : 1. The selection and evaluation of CD-ROM database are necessary steps in the planning of a CD-ROM. Before the CD-ROM is selected, therefore, medical libraries must make a practical evaluation criteria in important order of information services environment, characteristics of hardware/software, service requirements, price and cost, etc. 2. If possible, CD-ROM MEDLINE must be suited for the information services environment. 3. In case of the popular core journals, full-text CD-ROM should be gradually purchased. 4. In order to reduce the time required from search of bibliographic informations to receipt of original articles, CD-NET system and library holding administration program must be built up and developed. And channel of information search and order/receipt of original article should be varied. 5. Search education program for medical librarians and users should be enforced, and librarians must play an important role in CD-ROM retrieval consultant and intermediator.

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구조물 설계에 있어서 데이터베이스 관리 시스템의 응용에 관한 연구 -철근콘크리트 구조물 설계를 중심으로- (A Study on the Application of Database Management Systems to the Design of Structures -Cast of Reinforced Concrete Structure-)

  • 장주흠;윤성수;김한중;이정재
    • 한국농공학회지
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    • 제40권3호
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    • pp.103-112
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    • 1998
  • In this study, database schema which is capable of maintaining various design-knowledge and applicable to the structural designs has been presented. Futhermore, by utilizing the database system, RECODSS (REinforced COncrete Design Support System) was developed as well. Knowledge-base that were formulated from the document is constructed by applying the concrete standard specifications of Korea from 1989. The basic drawing was prepared by $AutoCAD^TM$. As an inference in the preliminary design, the certainty function and the interpolation function were presented. The certainty function is made by assuming linear relations between each data while referencing $MYCIN^TM$ (expert systems). Nevertheless, the interpolation function was made by utilizing the linear Lagrange interpolation. For the search of the design-knowledge, fast search algorithm and full-text search algorithm were used, however, the design engine was programmed with C language. RECODSS was applied for designing a slab and a beam member. And the results were compared with the existing results. In conclusion, RECODSS was able to efficiently manage various design knowledge and to introduce stable design results.

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인메모리 관계형 데이터베이스 시스템을 이용한 대용량 텍스트 로그 데이터의 패턴 매칭 방법 (A Pattern Matching Method of Large-Size Text Log Data using In-Memory Relational Database System)

  • 한혁;최재용;진성일
    • 한국정보처리학회:학술대회논문집
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    • 한국정보처리학회 2017년도 춘계학술발표대회
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    • pp.837-840
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    • 2017
  • 각종 사이버 범죄가 증가함에 따라 실시간 모니터링을 통한 사전 탐지 기술뿐만 아니라, 사후 원인 분석을 통한 사고 재발 방지 기술의 중요성이 증가하고 있다. 사후 분석은 시스템에서 생산된 다양한 유형의 대용량 로그를 기반으로 분석가가 보안 위협 과정을 규명하는 것으로 이를 지원하는 다양한 상용 및 오픈 소스 SW 존재하나, 대부분 단일 분석가 PC에서 운용되는 파일 기반 SW로 대용량 데이터에 대한 분석 성능 저하, 다수 분석가 간의 데이터 공유 불가, 통계 연관 분석 한계 및 대화형 점진적 내용 분석 불가 등의 문제점을 해결하지 못하고 있다. 이러한 문제점을 해결하기 위하여 고성능 인메모리 관계형 데이터베이스 시스템을 로그 스토리지로 활용하는 대용량 로그 분석 SW 개발하였다. 특히, 기 확보된 공격자 프로파일을 활용하여 공격의 유무를 확인하는 텍스트 패턴 매칭 연산은 전통적인 관계형 데이터베이스 시스템의 FTS(Full-Text Search) 기능 활용이 가능하나, 대용량 전용 색인 생성에 따른 비현실적인 DB 구축 소요 시간과 최소 3배 이상의 DB 용량 증가로 인한 시스템 리소스 추가 요구 등의 단점이 있다. 본 논문에서는 인메모리 관계형 데이터베이스 시스템 기반 효율적인 텍스트 패턴 매칭 연산을 위하여, 고성능의 대용량 로그 DB 적재 방법과 새로운 유형의 패턴 매칭 방법을 제안하였다.

A review of cognitive orientation to daily occupational performance with stroke

  • Ahn, Si-Nae
    • Physical Therapy Rehabilitation Science
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    • 제6권4호
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    • pp.202-207
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    • 2017
  • Objective: The self-decisions of the client regarding the meaningful work as a therapeutic approach of client-orientation. The Cognitive Orientation to daily Occupational Performance (CO-OP) is an occupation-oriented problem-solving approach. The purpose of this study was to describe the goals and intervention protocols of CO-OP in those affected by stroke. Design: A systematic review. Methods: Using EBSCOhost, PubMed, and ProQuest databases, we searched studies published in the past decade that utilized the CO-OP intervention. An initial search revealed 71,171 potential articles. After applying our search criteria to screen the titles, abstracts, and full-text, we included 7 articles that met our inclusion and exclusion criteria. In this study, we used the patient, intervention(s), comparison, outcome method to analyze the 7 selected studies. We analyzed the frequency of goals and intervention protocols. Results: Seven articles met our selection criteria; these studies included participants with an almost normal cognitive function from inpatient and outpatient rehabilitation facilities. CO-OP was used for 237 goals; the most used goal was the instrumental activities of daily living. The training procedure used 3 types of self-selecting goals in the activities. One of the goals was not trained, but was only evaluated to determine the generation effect. The most common outcome measurements included the Canadian Occupational Performance Measure and the Performance Quality Rating Scale. Conclusions: This research provided information about the effectiveness of CO-OP and selecting the correct evaluation tool to assess the efficiency of the intervention. This study suggests that treatment with CO-OP in occupational therapy is effective and that it outlines common protocols.

Reconstructive Trends in Post-Ablation Patients with Esophagus and Hypopharynx Defect

  • Ki, Sae Hwi;Choi, Jong Hwan;Sim, Seung Hyun
    • 대한두개안면성형외과학회지
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    • 제16권3호
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    • pp.105-113
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    • 2015
  • The main challenge in pharyngoesophageal reconstruction is the restoration of swallow and speech functions. The aim of this paper is to review the reconstructive options and associated complications for patients with head and neck cancer. A literature review was performed for pharynoesophagus reconstruction after ablative surgery of head and neck cancer for studies published between January 1980 to July 2015 and listed in the PubMed database. Search queries were made using a combination of 'esophagus' and 'free flap', 'microsurgical', or 'free tissue transfer'. The search query resulted in 123 studies, of which 33 studies were full text publications that met inclusion criteria. Further review into the reference of these 33 studies resulted in 15 additional studies to be included. The pharyngoesophagus reconstruction should be individualized for each patient and clinical context. Fasciocutaneous free flap and pedicled flap are effective for partial phayngoesophageal defect. Fasciocutaneous free flap and jejunal free flap are effective for circumferential defect. Pedicled flaps remain a safe option in the context of high surgical risk patients, presence of fistula. Among free flaps, anterolateral thigh free flap and jejunal free flap were associated with superior outcomes, when compared with radial forearm free flap. Speech function is reported to be better for the fasciocutaneous free flap than for the jejunal free flap.

얼굴마비의 임상연구병행 경제성평가 프로토콜 개발을 위한 체계적 문헌고찰연구 (Systematic Review for the Development of the Clinical Study with Economical Assessment Protocol on Facial palsy)

  • 공나경;서은성;선지혜;김남권
    • 대한한의학회지
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    • 제38권1호
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    • pp.46-55
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    • 2017
  • Objectives: The aim of this study is reviewing the literature to extract the key parameter, study design, perspective, cost-effectiveness index and find the calibration parameter for the clinical study with economical evaluation protocol on facial palsy. Methods: Literature search is performed using PUBMED for literature published from January 2000 to December 2016. We included randomized controlled trials(RCTs) and modelling study with economic assessment in which human participated. Results: As a result of literature search, the 198 articles were found. After reviewing the title, abstract and full text, the 5 articles were selected. Selected articles are classified into 4 RCT studies dealing with quality of life and 1 CEA(cost-effectiveness analysis) study. Conclusions: We found reliable key parameters, calibration parameters and elements of economical assessment study, which might be necessary factors for developing research protocol of clinical trial with economic evaluation about facial palsy patients.

우리나라 초등학생의 식품알레르기 현황과 영양(교)사의 식품알레르기 인식 변화에 대한 고찰, 1995~2015 (Changes of prevalence of food allergy in elementary school student and perception of it in school nutritionist in Korea, 1995~2015)

  • 한선미;허영란
    • Journal of Nutrition and Health
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    • 제49권1호
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    • pp.8-17
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    • 2016
  • Purpose: The aim of this study is to summarize and report on the change of food allergy in elementary school students and perception and practices in school nutritionists in Korea from 1995 to 2015. Methods: The search strategy was "(food allergy AND elementary school AND Korea) AND (nutritionist OR perception OR practice)". The search was conducted via KISS, DBPIA, RISS, NDSL, PubMed, Scopus, and Google scholar and full text and abstracts on the topic of food allergy evaluating prevalence, allergen, symptom, perception and practices were included in this review. Results: Out of 1379 records found in the sources, 13 related studies were included in the final analysis. The results showed that the number of students who had experienced food allergy was increasing. The two frequent allergenic foods were eggs and milk. The perception and practices of food allergy in school nutritionists was gradually increased. Conclusion: Further objective evaluations are required to confirm the food allergy status and its management in school.

메니에르 병의 침 치료에 관한 최근 임상 연구 동향 (Recent Clinical Research Trends on Acupuncture Treatment of Meniere's Disease)

  • 이규영;홍철희
    • 한방안이비인후피부과학회지
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    • 제31권3호
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    • pp.26-38
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    • 2018
  • Objectives : The purpose of this study is to investigate the possibility of applying acupuncture to the treatment of meniere's disease, which has no definite treatment methods, by analyzing the latest clinical researches about acupuncture treatment of meniere's disease. Methods : A case study and Randomized Controlled Trial (RCT) related to the acupuncture treatment of meniere's disease were searched using domestic and international thesis search engines including OASIS, CNKI, J-STAGE, PubMed. This study include acupuncture treatment and acupuncture combined with other treatments such as herbal medicine. The search was limitied to the publication date from 2000 to 2018 with free full text. Results : 17 cases were selected. There were 7 case studies in Korea, 5 case studies in China, and 5 RCT papers in China. All 12 cases reported improvement in meniere's disease and all RCT studies showed significantly higher treatment effects in the experimental group than in the control group. Conclusions : Acupuncture treatment showed significant effects for meniere's disease when applied alone or in combination with other treatments. In the future, various systematic studies should be conducted only for acupuncture treatment.

Analysis of research on developmentally supportive care for prematurity in neonatal intensive care unit: a scoping review

  • Lee, Hanna;Park, Ji Hyeon;Cho, Haeryun
    • Child Health Nursing Research
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    • 제28권1호
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    • pp.9-22
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    • 2022
  • Purpose: The purpose of this study was to identify the gaps in research related to developmentally supportive care in the neonatal intensive care unit (NICU). The ultimate goal was to explore directions of further research on developmentally supportive care for premature patients. Methods: The Arksey and O'Malley scoping review method was used. Articles on developmentally supportive care for preterm infants in the NICU, written in English or Korean, were identified through electronic search engines. A total of 279 papers were identified in the initial search, of which 22 full-text papers were included in this review. Results: Several nursing studies have been published in the past 5 years. The important elements of developmentally supportive care were family-centered care and management of the NICU environment. The primary developmentally supportive care interventions were training programs to promote the care competency of NICU nurses. Conclusion: It is necessary to actively develop comprehensive developmental support interventions that consider the various elements of developmentally supportive care for preterm infants. Additional studies should be done to develop programs that provide direct intervention for premature infant and their families.