• Structural Engineering and Mechanics
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• v.24 no.6
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• pp.709-725
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• 2006

In this paper the buckling and post-buckling behavior of slender bars under self-weight are studied. In order to study the post-buckling behavior of the bar, a geometrically exact formulation for the non-linear analysis of uni-directional structural elements is presented, considering arbitrary load distribution and boundary conditions. From this formulation one obtains a set of first-order coupled nonlinear equations which, together with the boundary conditions at the bar ends, form a two-point boundary value problem. This problem is solved by the simultaneous use of the Runge-Kutta integration scheme and the Newton-Raphson method. By virtue of a continuation algorithm, accurate solutions can be obtained for a variety of stability problems exhibiting either limit point or bifurcational-type buckling. Using this formulation, a detailed parametric analysis is conducted in order to study the buckling and post-buckling behavior of slender bars under self-weight, including the influence of boundary conditions on the stability and large deflection behavior of the bar. In order to evaluate the quality and accuracy of the results, an experimental analysis was conducted considering a clamped-free thin-walled metal bar. As this kind of structure presents a high index of slenderness, its answers could be affected by the introduction of conventional sensors. In this paper, an experimental methodology was developed, allowing the measurement of static or dynamic displacements without making contact with the structure, using digital image processing techniques. The proposed experimental procedure can be used to a wide class of problems involving large deflections and deformations. The experimental buckling and post-buckling behavior compared favorably with the theoretical and numerical results.

• Smart Structures and Systems
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• v.15 no.3
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• pp.683-698
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• 2015

Railroad bridges form an integral part of railway infrastructure throughout the world. To accommodate increased axel loads, train speeds, and greater volumes of freight traffic, in the presence of changing structural conditions, the load carrying capacity and serviceability of existing bridges must be assessed. One way is through system identification of in-service railroad bridges. To dates, numerous researchers have reported system identification studies with a large portion of their applications being highway bridges. Moreover, most of those models are calibrated at global level, while only a few studies applications have used globally and locally calibrated model. To reach the global and local calibration, both ambient vibration tests and controlled tests need to be performed. Thus, an approach for system identification of a railroad bridge that can be used to assess the bridge in global and local sense is needed. This study presents system identification of a railroad bridge using free vibration data. Wireless smart sensors are employed and provided a portable way to collect data that is then used to determine bridge frequencies and mode shapes. Subsequently, a calibrated finite element model of the bridge provides global and local information of the bridge. The ability of the model to simulate local responses is validated by comparing predicted and measured strain in one of the diagonal members of the truss. This research demonstrates the potential of using measured field data to perform model calibration in a simple and practical manner that will lead to better understanding the state of railroad bridges.

• Journal of the Society of Naval Architects of Korea
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• v.29 no.3
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• pp.140-148
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• 1992

The free vibration problem of symmetrically laminated composite rectangular plates is formulated based on anisotropic thick plate theory including the effects of shear deformation and rotary inertia. Considering the difficulty of obtaining closed-form solutions, Rayleigh-Ritz analysis using polynomials having the property of Timoshenko beam functions as trial functions is adopted. The boundary conditions elastically restrained against rotation are accomodated as well as classical boundary conditions. From the results of numerical studies, the validity of the present method is verified. And it is also found that the adoption of thick plate theory for the vibration analysis of laminated composite plates is essential because of the relatively large shear deformation effect, and that the convergence of the Rayleigh quotient to the stationary value is less rapid in anisotropic composite plates than that in the orthotropic ones due to more complicated mode shapes of the former.

• Archives of Pharmacal Research
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• v.29 no.5
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• pp.384-393
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• 2006

Protein carboxylmethylation methylates the free carboxyl groups in various substrate proteins by protein carboxyl O-methyltransferase (PCMT) and is one of the post-translational modifications. There have been many studies on protein carboxylmethylation. However, the precise functional role in mammalian systems is unclear. In this study, immunoglobulin, a specific form of $\gamma-globulin$, which is a well-known substrate for PCMT, was chosen to investigate the regulatory roles of protein carboxylmethylation in the immune system. It was found that the anti-BSA antibody could be carboxylmethylated via spleen PCMT to a level similar to $\gamma-globulin$. This carboxylmethylation increased the hydrophobicity of the anti-BSA antibody up to 11.4%, and enhanced the antigen-binding activity of this antibody up to 24.6%. In particular, the Fc region showed a higher methyl accepting capacity with 80% of the whole structure level. According to the amino acid sequence alignment, indeed, 7 aspartic acids and 5 glutamic acids, as potential carboxylmethylation sites, were found to be conserved in the Fc portion in the human, mouse and rabbit. The carboxylmethylation of the anti-BSA antibody was reversibly demethylated under a higher pH and long incubation time. Therefore, these results suggest that protein carboxylmethylation may reversibly regulate the antibody-mediated immunological events via the Fc region.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.42 no.3 s.303
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• pp.63-72
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• 2005

In this paper, we propose a deformation technique based on Radial Basis Function (RBF) and a blending technique combining the deformed facial component with the original face for a Virtual Aesthetic Surgery (VAS) system. The deformation technique needs the smoothness and the accuracy to deform the fluid facial components and also needs the locality not to affect or distort the rest of the facial components besides the deformation region. To satisfy these deformation characteristics, The VAS System computes the degree of deformation of lattice cells using RBF based on a Free-Form Deformation (FFD) model. The deformation error is compensated by the coefficients of mapping function, which is recursively solved by the Singular Value Decomposition (SVD) technique using SSE (Sum of Squared Error) between the deformed control points and target control points on base curves. The deformed facial component is blended with an original face using a blending ratio that is computed by the Euclidean distance transform. An experimental result shows that the proposed deformation and blending techniques are very efficient in terms of accuracy and distortion.

• Bulletin of the Society of Naval Architects of Korea
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• v.23 no.4
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• pp.25-34
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• 1986

A two-dimensional linear method has been developed for the motion and the second-order steady force arising from the hydrodynamic coupling between waves and currents in the presence of a body of arbitrary shape. Interaction between the incident wave and current in the absence of the body lies in the realm beyond our interest. A Fredholm integral equation of the second kind is employed in association with the Haskind's potential for a steadily moving source of pulsating strength located in or below the free surface. The numerical calculations at the preliminary stage showed a significant fluctuation of the hydrodynamic forces on the surface-piercing body. The problem is approximately solved by using the asymptotic Green function for $U^2{\rightarrow}0$. The original Green function, however, is applied for the fully submerged body. Numerical calculations are made for a submerged and for a half-immersed circular cylinder and extensively for the mid-ship section of a Lewis-form. Some of the results are compared with other analytical results without any available experimental data. The current has strong influence on roll motion near resonance. When the current opposes the waves, the roll response are generally negligible in the low frequency region. The current has strong influence on roll motion near resonance. When the current opposes the wave, the roll response decreases. When the current and wave come from the same direction, the roll response increases significantly, as the current speed increases. The mean drift forces and moment on the submerged body are more affected by current than those on the semi-immersed circular cylinder or on the ship-like section in the encounter frequency domain.

• The Research Journal of the Costume Culture
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• v.20 no.1
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• pp.49-61
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• 2012

This study focuses on looking at the influence of silhouette in the 1930s on fabric pattern design by comprehending how differently flower-pattern design were found according to clothing silhouette. The period scope of research was limited to 1930s, and the research object was set as the flower patterns seen in the designer's high-fashion and the women's daily apparel as well as the clothes for sports and leisure activities. Based on the above research scope, the researcher investigated the clothing silhouette and the textile patterns in 1930s by reviewing the literature about domestic and foreign books, research papers, domestic and foreign fashion magazines, information on the Internet. A glance at the women's clothing in the 1930s reveals that they emphasized something inactive, elegant, feminine and that great popularity was given to feminine silhouette that closely fitted the body and long and slim, as skirts became longer and longer. Like this, silhouette refused traditional methods in the technique of expressing flower patterns that were on-trend in that period, pursued the freedom of line and form, used shadowing technique by means of free pens and brushes and the effect of watercolors. It also arranged in a semitransparent way and painted contours alone, too. Flower patterns fell into two categories: amorphous abstract patterns and standardized abstract patterns. The patterns expressed themselves, divided into small-scale irregular patterns and abstract geometric patterns that filled the entire textile.

• Journal of the Korean Chemical Society
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• v.18 no.1
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• pp.50-57
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• 1974

A practical method applicable to the synthesis of aromatic dihydrazines was proposed by reducing tetrazonium salt in strong mineral acid media. By diazotizing p-phenylenediamine with sodium nitrite in a medium of concentrated hydrochloric acid or 45 % perchloric acid at $-5 {\sim} -10{\circ}C$ and reducing the tetrazonium salt with stannous chloride, p-phenylenedihydrazine (PPDH) was separated in the form of hydrochloride as colorless fine needles. Since PPDH was subject to oxidation and unstable, the free base could not be isolated. PPDH${\cdot}$2HCl was decomposed at $^180{\circ}C$ without showing sharp melting point. It behaved largely as aromatic monohydrazines, and reacted immediately with aldehydes and ketones in acetate buffer, giving generally yellow to brownish condensation products, dihydrazones. This suggests that PPDH will react with dicarbonyl compounds producing high molecular polymers or cyclization products.

• YAKHAK HOEJI
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• v.43 no.6
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• pp.809-817
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• 1999

The effect of 2-(4-cyanophenyl)amino-1,4-naphthalenedione-3-pyridinium perchlorate (PQ5) on pla-telet aggregation and its action mechanisms were investigated with rat platelet. PQ5 inhibited the platelet aggregation induced by collagen ($6{\;}{\mu\textrm{g}}/ml$), thrombin (0.4 U/ml) and A23187 ($3{\mu}M$) in concentration-dependent manner with $IC_{50}$ values of 5.50, 25.89 and $37.12{\;}{\mu}M$, respectively. PQ5 also significantly reduced the thromboxane $A_2$ (TXA2) formation in a concentration dependent manner. The collagen-induced arachidonic acid (AA) release in [-3H]-AA incorporated platelet, an indication of the phospholipase $A_2$ activity, was decreased by PQ5 pretreatment PQ5 significantly inhibited the activity of thormboxane synthase only at high concentration ($100{\mu}M$), but did not affect the cyclooxygenase activity at all. Collagen-induced ATP release was significantly reduced by PQ5. Calcium-induced platelet aggregation experiment suggests that the elevation of intracellular free $Ca^{2+}$ concentration ($[Ca^{2+}]_i$) by collagen stimulation is decreased by the pretreatment of PQ5, which is due to the inhibition of calcium release from intracellular store and influx from outside of the cell. PQ5 did not showed the effect of anticoagulation as prothrombin time (PT) or activated partial thromboplastin time (APTT). Form these results, it is suggested that PQ5 exerts its antiplatelet activity through the inhibition of the intracellular $Ca^{2+}$ mobilization and the decrease of the $TXA_2$ synthesis.

• Korean Journal of Microbiology
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• v.25 no.3
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• pp.180-183
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• 1987

Stu I, type II restriction endonuclease, has been purified to homogeneity from Streptomyces tubercidicus (ATCC 25502), and its catalytic properties have been studied. For the purification of Stu I endonuclease free of nonspecific nucleases, DEAE-Sephadex (A-50), QAE-Sephadex (A-50) and Heparin-agarose column chromatography have been performed after ammonium sulfate fractionation of the crude extract. The enzyme was further purified by gel filtration using Sephadex G-100 column to obtain homogeneous form of protein. The single polypeptide species of Stu I endonuclease has a subunit molecular weight of 34,000 $\pm$ 1,000 daltons as judged by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate. Stu I endonuclease requires $Mg^{2+}$ ion for its activity and is maximally active at neutral pH (7.0-8.0) in the absence of NaCl.