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Effect of Physiologically Active Compounds Isolated from Platycodon grandiflorum on Streptozotocin-Induced Diabetic Rats (장생도라지 생리활성물질이 Streptozotocin으로 유발된 당뇨쥐에 미치는 영향)

  • 서종권;정영철;전성식;이영우;이수정;손미예;성낙주
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.6
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    • pp.981-986
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    • 2004
  • This study were investigated the effects of physiologically active compounds isolated from Platycodon grandiflorum on streptozotocin-induced diabetic rats. The experimental groups were divided into six groups, normal, diabetic control (CM), and four experimental groups (inulin (IN), inulin + saponin (IS), oligosaccharide (OS), and total extract group (WE)). The rats have free access to water and diet. Experimental groups were administered orally with inulin (630 mg/mL), inulin (630 mg/mL) + saponin (25.2 mg/mL), oligosaccharide (367.5 mg/mL), and total extract (225 mg/mL) into the diabetic rats for 5 weeks after STZ injection; The levels of fasting blood glucose in diabetic control increased by 10.0% for 5 weeks, but the level of blood glucose in inulin and total extract groups decreased by 21.3% and 21.2%, respectively. The concentrations of total cholesterol and triglyceride in serum of diabetic rats fed physiologically activity compounds were lower than those in diabetic control rats. HDL-cholesterol was similar among all the groups. Weights of testicle and heart were lighter, while weight of kidney was significantly increased in diabetic groups than normal group. The concentrations of serum protein insulin and albumin in diabetic groups were significantly decreased compared with those of the normal group. Urinary glucose excretion was decreased in inulin group than other diabetic groups.

A Study on Motion Estimation Encoder Supporting Variable Block Size for H.264/AVC (H.264/AVC용 가변 블록 크기를 지원하는 움직임 추정 부호기의 연구)

  • Kim, Won-Sam;Sohn, Seung-Il
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.12 no.10
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    • pp.1845-1852
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    • 2008
  • The key elements of inter prediction are motion estimation(ME) and motion compensation(MC). Motion estimation is to find the optimum motion vectors, not only by using a distance criteria like the SAD, but also by taking into account the resulting number of 비트s in the 비트 stream. Motion compensation is compensate for movement of blocks of current frame. Inter-prediction Encoding is always the main bottleneck in high-quality streaming applications. Therefore, in real-time streaming applications, dedicated hardware for executing Inter-prediction is required. In this paper, we studied a motion estimator(ME) for H.264/AVC. The designed motion estimator is based on 2-D systolic array and it connects processing elements for fast SAD(Sum of Absolute Difference) calculation in parallel. By providing different path for the upper and lower lesion of each reference data and adjusting the input sequence, consecutive calculation for motion estimation is executed without pipeline stall. With data reuse technique, it reduces memory access, and there is no extra delay for finding optimal partitions and motion vectors. The motion estimator supports variable-block size and takes 328 cycles for macro-block calculation. The proposed architecture is local memory-free different from paper [6] using local memory. This motion estimation encoder can be applicable to real-time video processing.

Social Welfare Informatization from the Viewpoint of Recipients: Applying Three Dimensions of Information Literacy (수급자의 생활세계 관점에서 바라본 사회복지정보화 : 정보 리터러시 3차원을 중심으로)

  • Jeon, Giok;Kim, Suyoung
    • Korean Journal of Social Welfare Studies
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    • v.49 no.2
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    • pp.257-295
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    • 2018
  • This study delineates how recipients access, understand, and make use of social welfare information in their life-worlds. Through this vivid illustration about recipients' information behaviors, this research aims to suggest that government-centred welfare informatization policy should be readjusted. South Korean government has made enormous efforts to deliver and share social welfare information and knowledge with recipients, by organizing IT eduction programmes, offering free computers, and opening welfare portals. However, despite of such endeavors, not a few recipients find difficulty in gaining, grasping, and using welfare information. In fact, welfare informatization programmes have so far been initiated by the governmental bureaucratic system, and the voice of recipients have hardly been reflected on the informatization policy. Starting from this problem, this study examines how low-income recipients perceive and accept social welfare information in their daily lives and reflects on social welfare information at their point. For this purpose, this research conducted in-depth interviews with 14 recipients and analyzed the data using a framework analysis method. Based on the results, it raises the need for the remodelling of current welfare informatization measures from the perspective of recipients rather than following the custom of the bureaucratic system.

Improvement of conception rate on Hanwoo; The key hormones and novel estrus detector

  • Joo, Young Ho;Jeong, Seung Min;Paradhipta, Dimas Hand Vidya;Lee, Hyuk Jun;Lee, Seong Shin;Choi, Jeong Seok;Noh, Hyeon Tak;Chang, Hong Hee;Kim, Eun Joong;Kim, Sam Churl
    • Journal of Animal Science and Technology
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    • v.63 no.6
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    • pp.1265-1274
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    • 2021
  • Two field experiments were conducted to improve the conception rate of Hanwoo cow. The first experiment aimed to investigate the physiological condition of Hanwoo cows on estrus, including metabolic profiles and body condition score (BCS). The second experiment investigated the effect of a novel estrus detector on the artificial insemination (AI) conception rate for Hanwoo cows. For the first experiment, 80 Hanwoo cows (2.5 ± 0.10 of parity), approximately one month before estrus, were housed in 16 pens and offered the experimental diets twice daily with free water access. The BCS were recorded, and blood was collected from the jugular veins just before AI. The collected blood was used to measure physiological conditions, such as metabolite and hormone levels. For the second experiment, each cow was equipped with a neck-mounted estrus detector collar, which had a sensor connected through the internet. Approximately one month before estrus, three hundred sixty Hanwoo cows (2.4 ± 0.21 of parity) were assigned into groups with or without W-Tag collar treatments. The animals were managed the same as in the first experiment. The pregnancy rate reached 55% in the first experiment. The concentration of luteinizing hormone (LH) was higher (p < 0.012; 1.56 vs. 1.08 ng/mL) in cows that were not pregnant (NPG) than in cows that were pregnant (PG) after AI. The BCS and other concentrations of metabolites and hormones in the blood were not different in both NPG and PG cows. The ranges of estrogen, LH, and follicle-stimulating hormone for PG cows were 11.9 to 39.0 pg/mL, < 0.25 to 1.98 ng/mL, and < 0.50 to 0.82 ng/mL, respectively. In the second experiment, cows with the estrus detector had lower days open (p < 0.001; 78.1 vs. 84.8 d), insemination frequency (p < 0.001; 1.26 vs. 2.52), and return of estrus (p < 0.001; 70.9 vs. 79.1 d) than those in cows without the estrus detector. In conclusion, the present study indicated that lower LH concentration just before AI potentially increased the pregnancy rate of Hanwoo cows. Furthermore, the application of estrus detectors to Hanwoo cows could improve the conception success rate for AI.

Smart City Energy Inclusion, Towards Becoming a Better Place to Live

  • Cha, Sang-Ryong
    • World Technopolis Review
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    • v.8 no.1
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    • pp.59-70
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    • 2019
  • Where is a better place to live? In the coming era, this should be more than simply a livable place. It should be an adaptable place that has a flexible system adaptable to any new situation in terms of diversity. Customization and real-time operation are needed in order to realize this technologically. We expect a smart city to have a flexible system that applies technologies of self-monitoring and self-response, thereby being a promising city model towards being a better place to live. Energy demand and supply is a crucial issue concerning our expectations for the flexible system of a smart city because it is indispensable to comfortable living, especially city living. Although it may seem that energy diversification, such as the energy mix of a country, is a matter of overriding concern, the central point is the scale of place to build grids for realizing sustainable urban energy systems. A traditional hard energy path supported by huge centralized energy systems based on fossil and nuclear fuels on a national scale has already faced difficult problems, particularly in terms of energy flexibility/resilience. On the other hand, an alternative soft energy path consisting of small diversified energy systems based on renewable energy sources on a local scale has limitations regarding stability, variability, and supply potential despite the relatively light economic/technological burden that must be assumed to realize it. As another alternative, we can adopt a holonic path incorporating an alternative soft energy path with a traditional hard energy path complimentarily based on load management. This has a high affinity with the flexible system of a smart city. At a system level, the purpose of all of the paths mentioned above is not energy itself but the service it provides. If the expected energy service is fixed, the conclusive factor in choosing a more appropriate system is accessibility to the energy service. Accessibility refers to reliability and affordability; the former encompasses the level of energy self-sufficiency, and the latter encompasses the extent of energy saving. From this point of view, it seems that the small diversified energy systems of a soft energy path have a clear advantage over the huge centralized energy systems of a hard energy path. However, some insuperable limitations still remain, so it is reasonable to consider both energy systems continuing to coexist in a multiplexing energy system employing a holonic path to create and maintain reliable and affordable access to energy services that cover households'/enterprises' basic energy needs. If this is embodied in a smart city concept, this is nothing else but smart energy inclusion. In Japan, following the Fukushima nuclear accident in 2011, a trend towards small diversified energy systems of a soft energy path intensified in order to realize a nuclear-free society. As a result, the Government of Japan proclaimed in its Fifth Strategic Energy Plan that renewable energy must be the main source of power in Japan by 2050. Accordingly, Sony vowed that all the energy it uses would come from renewable sources by 2040. In this situation, it is expected that smart energy inclusion will be achieved by the Japanese version of a smart grid based on the concept of a minimum cost scheme and demand response.

South and North Korean Collaboration for Natural Heritage Conservation across Demilitarized Zone : Its Significance and Challenges (비무장지대(DMZ) 자연유산 남북 공동협력의 의의와 과제)

  • Je, Jonggeel
    • Korean Journal of Heritage: History & Science
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    • v.52 no.1
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    • pp.242-257
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    • 2019
  • The Demilitarized Zone (DMZ) stretches two kilometers north and south from the Military Demarcation Line (MDL) of South and North Korea. This area was established as a weapons-free buffer zone when an armistice agreement was signed in 1953. However, there have been several very high-tension military standoffss over the past 65 years. On the South Korean side, civilian access to the Civilian Control Line (CCL) and beyond to the north has been restricted, and natural heritage has been well maintained. Natural heritage is defined as living things, their habitat and non-living things of the ecosystem which deserve to be protected. Research shows that a variety of flora and fauna, their habitat, marshes and geographical structures are found across the DMZ region. Although the DMZ region has not been such a good place for habitat conservation, we can say that this area may be the best location for restoration in terms of its variety of ecosystems and considerable land size. Restoration of course depends on future plans and management policies. This area, including the DMZ and the well-protected north of the CCL, will be the best habitat for endangered species of wild fauna and flora if we classify the various habitat types and create a habitat map. In doing this project, we need to include the estuary of the Han River and the lagoon (brackish water lake) of the East Sea coast. In addition, we must establish long-term plans for conservation and sustainable use and do international scientific research across the DMZ region in collaboration with scientists of South and North Korea and international experts. Mutual cooperation between the two Koreas for investigation and conservation efforts is paramount.

Pre-grouting for CHI of EPB shield TBM in difficult grounds: a case study of Daegok-Sosa railway tunnel (복합지반 EPB TBM 커터교체를 위한 그라우팅 수행 사례)

  • Kang, Sung-Wook;Chang, Jaehoon;Lee, Jae-Won;Kim, Dae-Young;Shin, Young-Jin
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.23 no.5
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    • pp.281-302
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    • 2021
  • Railway projects have been consistently increasing in Korea. In relation to this trend, the mechanized tunneling using Tunnel Boring Machine (TBM) is preferably applied for mining urban areas and passing under rivers. The TBM tunneling under difficult grounds like mixed faces with high water pressure could require ground improvements for stable TBM advance or safe cutter head intervention (CHI). In this study, pre-grouting works for CHI in Daegok-Sosa railway project are presented in terms of the grouting zone design, the executions and the results, the lessons learned from the experience. It should be mentioned that the grouting from inside TBM was carried out several times and turned out to be inefficient in the project. Therefore, grouting experiences from the surface are highlighted in this study. Jet grouting was implemented on CHI points on land, while permeation grouting off shore in the Han River, which mostly allow to access the cutter head of TBM in free air with stable faces. The results of CHI works have been analyzed and the lesson learned are suggested.

Growth performance and blood profiles of Hanwoo steers at fattening stage fed Korean rice wine residue

  • Kim, Seon Ho;Ramos, Sonny C.;Jeong, Chang Dae;Mamuad, Lovelia L.;Park, Keun Kyu;Cho, Yong Il;Son, Arang;Lee, Sang-Suk
    • Journal of Animal Science and Technology
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    • v.62 no.6
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    • pp.812-823
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    • 2020
  • The aim of this study was to investigate the effects of Korean rice wine residue (RWR) on the growth performance and blood profiles of Hanwoo steers in the fattening stage. In situ and in vivo experiments were conducted to analyze rumen fermentation characteristics and total tract digestibility, respectively. Three cannulated Hanwoo steers (mean body weight: 448 ± 30 kg) were used in both analyses. The growth performance of 27 experimental animals in the fattening stage (initial body weight: 353.58 ± 9.76 kg) was evaluated after 13 months of feeding. The animals were divided into three treatment groups (n = 9/group). The treatments comprised total mixed ration (TMR) only (CON), TMR + 10% RWR (10% RWR), and TMR + 15% RWR (15% RWR). The diets of equal proportions were fed daily at 08:00 and 18:00 h based on 2% of the body weight. The animals had free access to water and trace mineral salts throughout the experiment. Supplementation of 15% RWR significantly decreased (p < 0.05) the rumen fluid pH compared with the control treatment, but there was no significant difference in the total volatile fatty acid concentration. It also significantly increased (p < 0.05) dry matter digestibility compared with the other treatments. The total weight gain and average daily gain of the animals in the RWR-supplemented groups were significantly higher (p < 0.05) than those in the control group. Furthermore, the feed intake and feed efficiency of the RWR-supplemented groups were higher than those of the control group. Supplementation of RWR did not affect the alcohol, albumin, glucose, total cholesterol, triglyceride, and low-density lipoprotein concentrations, and aspartate aminotransferase and alanine transaminase activities in the blood; these parameters were within the normal range. The high-density lipoprotein and creatinine concentrations were significantly higher in the 15% RWR group, whereas the blood urea nitrogen concentration was significantly higher in the 10% RWR group than in the other groups. These results suggest that TMR with 15% RWR can serve as an alternate feed resource for ruminants.

An Experimental Discussion of Using Chaekmun in the Field of Politics (책문(策文)의 정치적 활용성에 관한 시론 - 정조시대 이가환의 「소하대기미앙궁론(蕭何大起未央宮論)」 분석을 중심으로 -)

  • Baek, Jin-woo
    • (The)Study of the Eastern Classic
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    • no.57
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    • pp.359-382
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    • 2014
  • This paper is an essay on Chaekmun(Answer papers of official examination in Pre-modern period). Especially I tried to point out the possibility of practical use in the field of politics. For this purpose, I analyzed an examination paper written by Lee Ga-hwan, and the title is "a debate about construction of the Miang palace". Exquisite writing skill is also important in Chaekmun, but it is not everything. The subject of Chaekmun concerns various fields such like politics, economy, society, culture, and history. So that writers should have sufficient knowledge and opinion. The King, as an examiner, wants to test retainers' ability both in writing and politics. In this paper, I focused on using in field of politics between the King and the retainers. And as an good example, I analyzed a paper which dealt the event of building huge palace named Miang palace. That is because the King reflects his concerns by setting exam questions. And his concerns also could not be free of contemporary political conditions. Therefore we should be careful of reading those articles. Regarding this, Lee Ga-hwan's article had a distinctive characteristic. Unlike any other articles dealing with same event, he tried to access through creative point of view. And his thought were much close to the King's heart.

Effect of multi-enzymes supplementation on growth performance, meat quality, ileal digestibility, digestive enzyme activity and caecal microbiota in broilers fed low-metabolizable energy diet

  • Yaqoob, Muhammad Umar;Yousaf, Muhammad;Iftikhar, Mubashir;Hassan, Safdar;Wang, Geng;Imran, Safdar;Zahid, Muhammad Umer;Iqbal, Waqar;Wang, Minqi
    • Animal Bioscience
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    • v.35 no.7
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    • pp.1059-1068
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    • 2022
  • Objective: This study was conducted to evaluate the effect of using low energy diet with multi-enzymes supplementation on different biological parameters in broilers. Methods: Three hundred Arbor Acres broiler chicks were randomly divided into three groups (Cont, standard metabolizable energy(ME); L-ME, ME reduced by 50 kcal/kg without enzyme; and L-ME-MES, L-ME diet was supplemented with multi-enzymes) with five replicates per group (20 chicks per replicate) at the start of second week. Grower and finisher diets were formulated according to breed specific guide and offered with free access in respective phase (two weeks for grower [8 to 21 d]; two weeks for finisher [22 to 35 d]). External marker method was used to measure the nutrient digestibility. After feeding trial, fifteen birds (one bird per replicate) were selected randomly and slaughtered for samples collection. Results: The results exhibited no effect (p>0.05) of dietary treatments on all parameters of growth performance, carcass traits, relative weight of internal organs except bursa and overall parameters of thigh meat quality. Relative weight of bursa was significantly (p<0.05) higher in L-ME than control. Multi-enzymes supplementation in low-ME diet significantly (p<0.05) improved the breast meat pH 24 h, digestibility of crude protein, duodenum weight and length, jejunal morphology, counts of Lactobacillus spp. and Bifidobacterium spp., lipase and protease activities than control. Jejunum length was increased in both L-ME and L-ME-MES treatments than that of the control (p<0.05). Breast meat cooking loss and color lightness was lower in L-ME (p<0.05) than control. Conclusion: It can therefore be concluded that broilers could be reared on low energy diet with supplementation of multi-enzymes without compromising the growth performance. In addition, it is beneficial for other biological parameters of broilers.