• Title/Summary/Keyword: frankincense

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Pro-inflammatory Cytokine Production Inhibitory Effects of Frankincence in Murine Macrophage (마우스의 대식세포에서 프랑킨센스의 염증성 사이토카인 분비 억제작용)

  • Park, Jeong-Sook
    • Journal of the Korea Convergence Society
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    • v.8 no.1
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    • pp.239-243
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    • 2017
  • This study aims to demonstrate the inhibitory effect of proinflammatory cytokines by using Frankinsense. The present data was designed to determine the production of the frankincence on pro-inflammatory factors such as $TNF-{\alpha}$ and $IL-1{\beta}$ in lipopolysaccharide(LPS) stimulated RAW264.7 macrophages cell. The cell toxicity was identified by CellTiter 96 AQueous One solution cell proliferation assay. To evaluate of anti-inflammatory effect of frankincence, pro-inflammatory cytokines were measured by ELISA kit. As a result, the frankincence reduced NO and $TNF-{\alpha}$ production without cytotoxicity. As a result, Francincense was not cytotoxic at 10 ug / ml-1000 ug / ml and significantly inhibited the proinflammatory cytokines $TNF-{\alpha}$ and $IL-1{\beta}$. The secretion inhibition effect of proinflammatory cytokine is believed to be applicable to various physiological activity data and functional materials to demonstrate the anti - inflammatory properties of frankincense.

Potential Anticancer Medicinal Plants -A Statistical Evaluation of Their Frequencies of Appearance in Oriental Medicine Formularies- (항암 및 항세균 생약의 통계학적 연구)

  • Cha, Sung-Man
    • Korean Journal of Pharmacognosy
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    • v.8 no.1
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    • pp.1-15
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    • 1977
  • In an attempt to deduce which plants might have been used for their anticancer activities in traditional oriental herb medicine, 127 prescriptions were selected from 'Dong-Eui-Bo-Gam', the Classic Handbook of Korean Traditional Medicine, written by $H_{UH}$ Jun and published in 1613. These are the prescriptions indicated for the systemic treatment of various tumors and some conditions resembling tumors, e.g. inflammatory masses and indurations, and they include 150 natural products of plant origin. The frequency of appearance of each medicinal plant in these selected prescriptions was compared with the frequency of its appearance in all prescriptions listed in 'Bang-Yak-Hap-Pyon', another popular Oriental Medicine Formulary in Korea, written by $H_{WANG}\;Pil-Su$ in 1885. From the latter book, $H_{ONG}$ has recently enumerated frequencies of 235 medicinal plants included in a total of 467 prescriptions. Chi-square tests revealed that 11 plant remedies appear with significantly higher frequency in the prescriptions for "tumors", and 10 for "inflammations". The plants with potential antitumor activities, in decreasing order of statistical significance, are Scirpus maritimus, Curcuma zedoaria, Prunus persica, Rheum coreanum, Foeniculum vulgare, Rhus vernifera, Daphne pseudogenkwa, Galarhaeus sieboldiana, Croton tiglium, Raphanus sativus and Galarhaeus pekinensis. The drugs for potential antibacterial or anti-inflammatory activities are Olibanum(Frankincense), Forsythia coreana, Lonicera japonica, Gleditchia officinalis, $M_{YRRH}$, Trichosanhes kirilowii, Astragalus membranaceus, Rheum coreanum, Platycodon grandiflorum and Fritillaria verticillata. Despite the uncertainties involved in the terminology of various diseases used in pre-modern medicine, and the reservations about the efficacy of remedies used for those diseases, it would be worthwhile to investigate these few selected plants for anticancer, antibacterial, anti-inflammatory or antifungal effects, employing modern scientific methodology.

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Study on the Research Trend of Aromatherapy and its Application with Korean Medicine (아로마테라피의 연구 동향과 한의학적 활용에 대한 고찰)

  • Lee, Seon-Kyung;Yoon, Mi-Young;Sohn, Kyung-Woo;Chae, Han
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.25 no.3
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    • pp.398-405
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    • 2011
  • This review was conducted to analyze the current situation of aromatherapy research and to provide novel approach to the application of aromatherapy in Korean medicine. We reviewed peer-reviewed research articles published in Korean journals since 1998 up to 2010 related to the medical use of aromatherapy. We searched six electronic database to find all relevant articles using the terms "aromatherapy", "aroma" in English and Korean, and hand searched relevant journal articles. Among 180 identified articles, 115 clinical trials and 28 articles related to the Korean medicine were analyzed. Results showed that the articles on aromatherapy increased steeply during 2001~2004 in various study fields. The clinical studies with psychological disorders (57 articles) and women (42.7%) are reported most frequently. Though the Korean medicine tried to adopt aromatherapy earlier than other fields for the similarity, but there had not been quite a number of studies supporting the clinical applications. Several herbs like frankincense, jasmine, neroli and sandalwood are using in both Korean medicine and aromatherapy. There were many attempts to combine aromatherapy and Korean medicine but still more studies are needed. Aromatherapy have been studied in many research fields with various medical applications. There have been efforts to deploy aromatherapy to the clinical use and the potential value for the clinical practice of Korean medicine can be examined with more rigorous and innovative studies.

Psychophysiological evaluation for naturally flavored cream products (천연향을 이용한 크림 제품의 심리생리적 평가)

  • Park, Se-Jin;Oh, Seung-Bin;Lee, Eun-Ju;Seo, Hyung-Jye
    • Science of Emotion and Sensibility
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    • v.15 no.1
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    • pp.9-16
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    • 2012
  • Generally, cosmetic creams have been used to moisturize and smooth human skin. Recently, people concerns about the creams released with natural flavors and its functionality. This study focused to assess the psychophysiological effects of creams with 5 natural flavors such as patchouli oil, frankincense, sandalwood oil, none and newly developed S6. Initially, we have performed subjective evaluation for 100 female subjects aged 20 to 30 from Daejeon, South Korea. The results showed the most preferred flavor was S6 condition. Second, physiological evaluations for 20 female subjects were measured with EEG, ECG and GSR. In EEG analysis, the alpha ratio was confirmed to appear higher in each condition. The statistical analysis shows that significantly largest effect at S6 condition($p$ <0.05). The result from ECG and GSR measurements also shows the same trend. Third, skin conditions were measured when using S6. As a result, the skin temperature, humidity and skin movement speed were increased with S6 condition. The moisturizing and elasticity effects were confirmed.

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A Study on the Correlation between Aroma Preferences and MMPI-2 Subscales in University Students (대학생의 아로마 선호도 및 MMPI-2 하부척도와의 상관성 연구)

  • Shin, Haegue;Lee, Jae-Hyok
    • Journal of Oriental Neuropsychiatry
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    • v.31 no.4
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    • pp.259-267
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    • 2020
  • Objectives: The purpose of this research was to examine the correlation between aroma preferences and Minnesota Multiphasic Personality Inventory-2 (MMPI-2) subscales. Methods: We analyzed the survey results of the aroma preference test and MMPI-2 from 109 university student samples. The data were analyzed using descriptive analysis, the independent t-test, and Pearson's correlation analysis. Results: 1. Clinical scales of MMPI-2 Hs showed a low positive correlation with lavender; MMPI-2 D with ylang-ylang, thyme, and lavender; MMPI-2 Hy with lavender; MMPI-2 Pd with thyme and lavender; MMPI-2 Mf with clary sage and lavender; MMPI-2 Pa with clary sage and lavender; MMPI-2 Pt with thyme and lavender; and MMPI-2 Sc with thyme and lavender. MMPI-2 D and Si showed a low negative correlation with rosemary; and MMPI-2 Mf, Pt, and Si with rose. 2. Restructured clinical scales RC1 showed a low positive correlation with ylang-ylang and lavender; RC2 with thyme and lavender; RC4 with jasmine; and RC6 with clary sage and lavender. RC2 and RC7 showed a low negative correlation with rosemary; RC4 with peppermint; and RC6 and RC8 with frankincense. Conclusions: According to the result of the aroma preference test, men preferred clary sage and women preferred rose. Peppermint was the most preferred aroma, while Roman chamomile was the least preferred aroma.

A study on the physiological activity effect as a cosmetic material using 3 kinds of domestic plants and combination oil (국내산 식물 3종과 조합 오일의 화장품 소재로서의 생리활성 효과 연구)

  • Jung, Sook Heui;Jung, Heui-Sook
    • Journal of the Korean Applied Science and Technology
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    • v.39 no.2
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    • pp.303-313
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    • 2022
  • In this study, the extracted oils and commercial oils (Clarisse) were analyzed after GC-MSD fragrance component analysis for each natural essential oil obtained through steam distillation extraction (cypress, seokchangpo, lavender) of a total of three plants grown and grown in Jangheung area. Easy, cinnamon, frankincense) was combined to confirm cytotoxicity, antioxidant, anti-inflammatory, and whitening effects, confirming its potential as a cosmetic material. As a result of the analysis of fragrance components, sabinene was identified as the main component of cypress oil, asarone in seokchangpo oil, and L-Linalool in lavender oil. At a concentration of 100 𝜇L/mL with no cytotoxicity of 6 essential combination oils, NO production was inhibited by 27.76%, DPPH radical scavenging activity was 99.69%, ABTS radical scavenging activity was 94.66%, and tyrosinase inhibitory activity was 55.9%. Possibility of being useful as a raw material for functional cosmetics was presented.

The Effect of Aroma Inhalation on the Preoperative Pain and Anxiety of the Elderly Preparing to Undergo Spine Surgery (척추 수술 전 노인환자에게 적용한 아로마 향흡입요법이 통증 및 불안에 미치는 효과)

  • Park, Sohwi;Kim, Bokyoung;Park, Kyungsook
    • Journal of Digital Convergence
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    • v.17 no.12
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    • pp.523-533
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    • 2019
  • This study's purpose is to determine the effects of aroma inhalation on preoperative pain and anxiety of the elderly preparing to undergo a spine surgery. A Quasi-experimental design, with non-equivalent control group non-synchronized design was used in this study. Blended essential oils with frankincense, marjoram and mandarin were inhaled twice in the experimental group (n=30). The control group (n=30) was treated with the standard preoperative care. Pain, state anxiety, and vital sign were measured twice (before and after). The results of this study showed that pain (t=-1.223, p=.226), systolic blood pressure (t=-0.211, p=.833), diastolic blood pressure (t=0.638, p=.526), and respiration rate (t=0.734, p=.466) were not statistically significant in the experimental and the control group. There were significant differences in state anxiety (t=-3.202, p=.002) and pulse rate (t=-0.213, p=.037) in the experimental group compared to the control group. According to the results, aroma inhalation is an effective nursing intervention for relieving anxiety in surgical patients.

A Study on the Vegetables Mentioned in the Bible (성서에 언급된 채소류에 관한 연구)

  • Woo, Ja-Won
    • Journal of the Korean Society of Food Culture
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    • v.22 no.1
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    • pp.1-9
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    • 2007
  • This paper is intended to study what kinds of the vegetables are mentioned in the Bible and how they were used in those days. While one hundred and twenty-eight different plants are mentioned in the Bible, there are today 2,384 plant species in modem Israel, most of which have been introduced in recent centuries. These plants obviously did not exist there in biblical times and were only recently introduced from Australia and South America, respectively. This article will study only the vegetables mentioned in the Bible and known to have existed in the old and new testament times. Since the first book devoted exclusively to biblical botany was that of Levinus Lemmens in 1566, the modem systematic study of biblical plants, began with F. Hasselquist, a student of Linnaeus, the founder of modem botany. In 1928, Immanuel Loew approached the subject differently, reviewing all known data pertaining to biblical plants. His work not only discussed biblical plants, but also plants in later Jewish literature, particularly the Talmud. The British scholar G. E. Post provided a broad field study of modem plants in Palestine, Syria, Lebanon, and Jordan. More recent major treatments of the subject include those of A. and H. Moldenke (1952), M. Zohary (1982), N. Hareuveni (1984), and Y. J. Choi(1996). Today, articles on specific biblical plants listed in the Bible can be found in any number of encyclopedias. This study attempts to provide a synthesis of the work of a number of scholars who studied the vegetables and plants mentioned in the Bible. As a preliminary study on the culture of food in the biblical period, this study has focused on the identity and features of the vegetables of the Bible. In only a limited number of instances, because of the paucity of the informations and the broad and generic descriptions of the plants, we can't be certain about the identification of the vegetables named in the Bible. In many instances the traditions established by the Greek, Aramaic, and English translations are helpful, although sometimes they are misleading. This paper subdivides the vegetables into broad areas, the general vegetables and the flavoring herbs. Vegetables formed very important part of the diet in the biblical times. Two main types were used: those whose nutritious seeds could be easily stored and those which were eaten freshly gathered from gardens. Pulse seeds provided a useful source of vegetable protein, while fresh green vegetables were vitamin rich. Pulses could be eaten boiled, or their dried seeds could be ground up into flour and then made into nutritious soups. Fresh vegetables were eaten either raw or lightly cooked, usually by boiling in water. The general vegetables in the Bible are herbs(garden rocket), cucumber(snake cucumber), watermelon, leeks, chicory, and onions. Also the flavoring herbs in the Bible are rue, dill, cummin, black cummin, frankincense, cinnamon, cassia, myrrh, black mustard, coriander, mint, saffron, ginger grass, syrian hyssop, aloes(eagle wood), manna which have the flavor, aroma, and medical values.