• 한국실내디자인학회논문집
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• 제24권1호
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• pp.72-81
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• 2015

The change towards meeting diverse customer needs has started to affect the hotel industry as well. Design hotels emerged as customers demanded differentiated lodging experiences they could not fulfill at franchise hotels which were uniform in style everywhere in the world. Design hotels are meant to provide a new concept of space through unique design sensibility and work of designers, which highlighted the role of interior design. This research analyzes the characteristics of indoor space expressed in design hotel common spaces by the French designer Andree Putman, also known as the founder of boutique hotels and the concept of design hotels. As the original founder of the concept of design hotels, Putman's scope of work stretches wide, from interior design to product design. She is also one of the few French designers with a modernist inclination. The research runs a review on previous literature, characteristics of design hotels according to design tendency, and the association with characteristics of indoor space designed by Andree Putman, followed by case analyses extracted by analyses on design characteristics of common spaces she has designed. The analysis reveals that she creates comfortable yet elegant space, using contrast and fusion arising from negotiation of design styles to interpret space, the sense of spatial balance and understated expression of order through symmetrical structures, diverse creation of space through geometric structuring, highlighting indoor space by utilizing lights as objects, and the heterogeneous harmony achieved by contrasting juxtaposition, and understated formativeness. It is expected that study results would be utilized as methods of new designs of interior space in design hotels.

• 한국안광학회지
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• 제13권1호
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• pp.1-4
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• 2008

목적: 본 연구는 소규모 안경원 창업에 관련된 여러 가지 유용한 정보를 제공하여, 안경원 창업준비에 관련된 시행착오를 줄이고자 한다. 방법: 경기도 지역에서 31개원의 소규모 안경원 개설자를 조사하였고, 그 중 응답이 불성실한 8개원의 설문지를 제외한 23개원의 설문지를 분석하였다. 소규모 안경원을 오픈한 창업주를 대상으로 질의 및 설문을 통해 진행하였다. 결과: 소규모 안경원 창업을 준비하기 전에 안경원 경력은 4~5년이 가장 많았다. 안경원 창업자의 남녀 비율은 남자(73.9%)가 여자(26.1%)보다 많았다. 창업의 준비기간은 3~5개월(47.8%)이 가장 많았다. 결론: 본 연구는 예비 창업자들에게 소규모 안경원 창업에 관한 유용한 정보를 제공한다.

• Journal of Ecology and Environment
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• 제45권3호
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• pp.97-104
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• 2021

Background: Asarum sieboldii Miq., a species of forest understory vegetation, is an herbaceous perennial belonging to the family Aristolochiaceae. The metapopulation of A. sieboldii is distributed sparsely and has a short seed dispersal distance by ants as their seed distributor. It is known that many flowers of A. sieboldii depend on self-fertilization. Because these characteristics can affect negatively in genetic structure, investigating habitat structure and assessment of genetic structure is needed. A total of 27 individuals in a valley were sampled for measuring genetic diversity, genetic distance, and genetic differentiation by RAPDPCR. Results: The habitat areas of A. sieboldii metapopulation were relatively small (3.78~33.60 m²) and population density was very low (five to seven individuals in 20×20 m quadrat). The habitat of A. sieboldii was a very shady (relative light intensity = 0.9%) and mature forest with a high evenness value (J = 0.81~0.99) and a low dominance value (D = 0.19~0.28). The total genetic diversity of A. sieboldii was quite high (h = 0.338, I = 0.506). A total of 33 band loci were observed in five selected primers, and 31 band loci (94%) were polymorphic. However, genetic differentiation along the valley was highly progressed (G_st = 0.548, N_m = 0.412). The average genetic distance between subpopulations was 0.387. The results of AMOVA showed 52.77% of variance occurs among populations, which is evidence of population structuring. Conclusions: It is expected that a small-scale founder effect had occurred, an individual spread far from the original subpopulation formed a new subpopulation. However, geographical distance between individuals would have been far and genetic flow occurred only within each subpopulation because of the low density of population. This made significant genetic distance between the original and new population by distance. Although genetic diversity of A. sieboldii metapopulation is not as low as concerned, the subpopulation of A. sieboldii can disappear by stochastic events due to small subpopulation size and low density of population. To prevent genetic isolation and to enhance the stable population size, conservative efforts such as increasing the size of each subpopulation or the connection between subpopulations are needed.

• 융합정보논문지
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• 제12권1호
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• pp.135-143
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• 2022

본 연구에서는 불레기말 추출물의 항산화능 및 항염활성을 확인하였다. 라디컬 소거능으로서 DPPH, ABTS, nitrite 소거능 실험, FRAP 실험, 항산화 물질 측정으로서 폴리페놀과 플라보노이드 농도 측정을 실시하였다. DPPH 실험에서는 2.821 mg ascorbic acid / g의 항산화능을 나타내었으며, ABTS 실험에서는 3.923 mg ascorbic acid / g의 항산화능을 나타내었으며, nitrite 소거능 실험에서는 17.89 mg ascorbic acid / g의 항산화능을 나타내었다. FRAP에서는 불레기말 추출물의 1 mg이 ascorbic acid 2.062±0.177 ㎍의 환원력을 보였다. 폴리페놀 농도는 62.85±3.18 mg/g으로 나타났다. 플라보노이드 농도는 10.01±0.24 mg/g으로 나타났다. 한편 세포실험에서는 세포독성과 항염활성을 알아보았다. 세포독성의 경우 20% 이하의 세포 독성을 보였으며, 100 ㎍/mL 농도에서 30.93±2.93%의 염증 억제능을 보여 불레기말 추출물의 기능성 화장품 원료로서의 가능성을 확인하였다.

• Animal Bioscience
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• 제36권5호
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• pp.692-703
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• 2023

Objective: The main goals of this investigation were to i) assess the population structure and genetic diversity and ii) determine the efficiency of the ongoing breeding program in a closed flock of Angora rabbits through pedigree analysis. Methods: The pedigree records of 6,145 animals, born between 1996 to 2020 at NTRS, ICAR-CSWRI, Garsa were analyzed using ENDOG version 4.8 software package. The genealogical information, genetic conservation index and parameters based on gene origin probabilities were estimated. Results: Analysis revealed that, 99.09% of the kits had both parents recorded in the whole dataset. The completeness levels for the whole pedigree were 99.12%, 97.12%, 90.66%, 82.49%, and 74.11% for the 1st, 2nd, 3rd, 4th, and 5th generations, respectively, reflecting well-maintained pedigree records. The maximum inbreeding, average inbreeding and relatedness were 36.96%, 8.07%, and 15.82%, respectively. The mean maximum, mean equivalent and mean completed generations were 10.28, 7.91, and 5.51 with 0.85%, 1.19%, and 1.85% increase in inbreeding, respectively. The effective population size estimated from maximum, equivalent and complete generations were 58.50, 27.05, and 42.08, respectively. Only 1.51% of total mating was highly inbred. The effective population size computed via the individual increase in inbreeding was 42.83. The effective numbers of founders (f_e), ancestors (f_a), founder genomes (f_g) and non-founder genomes (f_ng) were 18, 16, 6.22, and 9.50, respectively. The fe/fa ratio was 1.12, indicating occasional bottlenecks had occurred in the population. The six most influential ancestors explained 50% of genes contributed to the gene pool. The average generation interval was 1.51 years and was longer for the sire-offspring pathway. The population lost 8% genetic diversity over time, however, considerable genetic variability still existed in the closed Angora population. Conclusion: This study provides important and practical insights to manage and maintain the genetic variability within the individual flock and the entire population.

• 벤처창업연구
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• 제19권1호
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• pp.23-31
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• 2024

본 연구는 정부 주도사업이 투자자의 투자의사 결정 준거점에 미치는 영향을 실증적으로 탐색한다. 전망이론과 인적자원 이론을 접목하여 창업자의 인적자원 요소들을 준거점으로 활용하였다. 정부 주도사업의 영향으로 인해 투자자의 준거점에 변화가 있는지 실증적으로 탐색하였으며, 정부가 주도하고 지원하는 사업에 대해 민간이 투자할 때 고려해야 할 점을 시사한다. 연구 자료는 2017년 5월부터 2022년 5월까지 한국판 뉴딜에 해당하는 기업 51개와 해당하지 않는 기업 49개를 조사했으며 창업자 과거 창업 경험, 기술 산업 경력 기간, 경영관리 경력 기간, 최종학력 교육연수, 그리고 최종 졸업학교의 명성을 준거점으로 측정하여 연구를 진행했다. 회귀분석 결과 졸업학교 명성이 정부 주도사업과 부(-)의 영향을 미치는 것으로 나타났으며, 투자자의 준거점이 변화되는 것을 확인하였다.

• 한국한의학연구원논문집
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• 제1권1호
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• pp.363-400
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• 1995

The electroacupuncture according to Voll(EAV) is a method of combining the fundamentals of classical acupuncture with the facilities of modern electronics for diagnostics and therapy. Classical acupuncture uses energy conducting lines called 'meridians' and acupuncture points situated along them. Dr. Voll is considered the founder of 'EAV' since he succeeded not only in finding a method of exact electric localization and in explaining the interelation between the acupuncture points and their individual organs, but he also succeeded in measuring the resistance of these points and in explaining the diagnostic meaning of the measured values. In the course of his research, Voll found numerous new measurement points and energy conducting vessels unknown to classical acupuncture, but indispensible for diagnosis of human organic functions. As a basis of modern research in meridian theory, I tried to compare EAV measurement point with classical acupuncture point.

• Bulletin of the Korean Chemical Society
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• 제33권5호
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• pp.1536-1540
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• 2012

Chicken primordial germ cells (cPGCs) are founder germ cells in embryonic stage of development that eventually give rise to sperms or oocytes. Currently cPGCs are only known cells enabling germline transmission in chicken and their cultivation protocols were recently established. Although genome modifications of chickens are now theoretically possible using cPGCs, there are still several hurdles to overcome to practically use cPGCs as mediators for chicken transgenesis. First, efficiency of gene delivery into cPGCs remains low with current methods. Second, there aregene silencing mechanisms against the expression of foreign genes in cPGCs. In this study, we successfully increased the efficiency of gene delivery in cPGCs by taking advantage of the TTAA-specific $piggybac$ transposon system. Moreover, a pipette-type electroporator significantly enhanced transfection efficiency up to 5-fold compared withcuvette-type methods. Taken together, the technological advances in our study will provide practical benefits for the application to fulfill genetic modifications of chicken genome.

• 교통기술과정책
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• 제4권3호
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• pp.105-116
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• 2007

Walking is the first thing an infant wants to do and the last thing an old person wants to give up. Walking is the exercise that does not need a gym. It is the prescription without medicine, the weight control without diet, and the cosmetic that can't be found in a chemist. It is the tranquillizer without a pill, the therapy without a psychoanalyst, and the holiday that does not cost a penny. What's more, it does not pollute, consumers few natural resources and is highly efficient. Walking is convenient, it needs no special equipment, is self-regulating and inherently safe. Walking is as natural as breathing. John Butcher, Founder Walk21, 1999.

• 한국실내디자인학회:학술대회논문집
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• 한국실내디자인학회 2006년도 추계학술발표대회 논문집
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• pp.197-198
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• 2006

The latest university makes the use of exhibition hall bring into relief a specific character and identity. This purpose of this design is to induce interest the exhibition plan, that is useful to appreciation of audience according to space structure. The concept of this design is to design continual circulation plan and to give correctness Information of the exhibit. Because to this exhibition hall is too small space, this design focus is continual circulation plan. The exhibit is classified to according to the character of that, which is distinguished according to the colour plan. The center of the hall is main image hall of university. The right space of the main hail is university history exhibition hall and the left space of the hall is a founder memorial hall. The main colour is light cream. An image object colour plan is point colou, which is bluish green colour.