• Economic and Environmental Geology
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• v.29 no.3
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• pp.325-333
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• 1996

numerical model is developed to estimate gas flow in the landfill site. Darcy's law, the mass conservation law, and the ideal gas state equation are combined to compose the governing equation for the steady-state and transient-state gas flows. The finite element method (FEM) is used as the numerical solution scheme. Two-dimensional radial symmetric triangular ring element is used to discretize the simulation domain. The steady state model developed in this study is compared with AIRFLOW that is a commercial model developed by Hydrologic Inc. Mass balance test is performed on the transient gas flow simulation. The developed model is applied to analyze the gas extraction experiment performed by Daewoo Institute of Construction Technology at the Nanjido landfill in 1993. The developed model was registered at Korea Computer Program Protection Foundation.

• Mass Spectrometry Letters
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• v.9 no.1
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• pp.24-29
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• 2018

DC23, a triazolothione resorcinol analogue, is known to inhibit heat shock protein 90 and pyruvate dehydrogenase kinase which are up-regulated in cancer and diabetes, respectively. This study was performed to elucidate the metabolism of DC23 in human liver microsomes (HLMs). HLMs incubated with DC23 in the presence of uridine 5'-diphosphoglucuronic acid (UDPGA) and/or ${\beta}$-nicotinamide adenine dinucleotide phosphate (NADPH) resulted in the formation of four metabolites, M1-M4. M1 was identified as DC23-N-Oxide, on the basis of LC-MS/MS analysis. DC23 was further metabolized to its glucuronide conjugates (M2, M3, and M4). In vitro metabolic stability studies conducted with DC23 in HLMs revealed significant glucuronide conjugation with a $t_{1/2}$ value of 1.3 min. The inhibitory potency of DC23 on five human cytochrome P450s was also investigated in HLMs. In these experiments, DC23 inhibited CYP2C9-mediated tolbutamide hydroxylase activity with an $IC_{50}$ value of $8.7{\mu}M$, which could have implications for drug interactions.

• Structural Engineering and Mechanics
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• v.85 no.3
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• pp.381-391
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• 2023

The seismic performance of the tall building equipped with a tuned mass damper (TMD) considering soil-structure interaction (SSI) effects is well studied in the literature. However, these studies are performed on the nominal model of the seismic-excited structural system with SSI. Hence, the outcomes of the studies may not valid for the actual structural system. To address the study gap, the reliability theory as a useful and powerful method is utilized in the paper. The present study aims to carry out reliability analyses on tall buildings equipped with TMD under near-field pulse-like (NFPL) ground motions considering SSI effects using a subset simulation (SS) method. In the presence of uncertainties of the structural model, TMD device, foundation, soil, and near-field pulse-like ground motions, the numerical studies are performed on a benchmark 40-story building and the failure probabilities of the structures with and without TMD are evaluated. Three types of soils (dense, medium, and soft soils), different earthquake magnitudes (M_w = 7,0. 7,25. 7,5 ), different nearest fault distances (r = 5. 10 and 15 km), and three seismic performance levels of immediate occupancy (IO), life safety (LS), and collapse prevention (CP) are considered in this study. The results show that tall buildings built near faults and on soft soils are more affected by uncertainties of the structural and ground motion models. Hence, ignoring these uncertainties may result in an inaccurate estimation of the maximum seismic responses. Also, it is found the TMD is not able to reduce the failure probabilities of the structure in the IO seismic performance level, especially for high earthquake magnitudes and structures built near the fault. However, TMD is significantly effective in the reduction of failure probability for the LS and CP performance levels. For weak earthquakes and long fault distances, the failure probabilities of both structures with and without TMD are near zero, and the efficiency of the TMD in the reduction of failure probabilities is reduced by increasing earthquake magnitudes and the reduction of fault distance. As soil softness increases, the failure probability of structures both with and without TMD often increases, especially for severe near-fault earthquake motion.

• Computers and Concrete
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• v.34 no.4
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• pp.409-425
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• 2024

This paper utilizes LS-DYNA software to numerically investigate impact response and damage evaluation of fiber-reinforced polymer (FRP) bars-reinforced ultra-high-performance concrete (UHPC) composite beams (FRP-UHPC beams). Three-dimensional finite element (FE) models are established and calibrated by using literature-based static and impact tests, demonstrating high accuracy in simulating FRP-UHPC beams under impact loading. Parametric analyses explore the effects of impact mass, impactor height, FRP bar type and diameter, and clear span length on dynamic response and damage modes. Two failure modes emerge: tensile failure with bottom longitudinal reinforcement fracture and compression failure with local concrete compression near the impact region. Impact mass or height variation under the same impact energy significantly affects the first peak impact force, but minimally influences peak midspan displacement with a difference of no more than 5% and damage patterns. Increasing static flexural load-carrying capacity enhances FRP-UHPC beam impact resistance, reducing displacement deformation by up to 30%. Despite similar static load-carrying capacities, different FRP bars result in varied impact resistance. The paper proposes a damage assessment index based on impact energy, static load-carrying capacity, and clear span length, correlating well with beam end rotation. Their linearly-fitting coefficient was 1.285, 1.512, and 1.709 for the cases with CFRP, GFRP, and BFRP bars, respectively. This index establishes a foundation for an impact-resistant design method, including a simplified formula for peak midspan displacement assessment.

• Molecules and Cells
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• v.24 no.3
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• pp.437-440
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• 2007

$OGL-20P^T$-358 is a novel 66 amino acid residue protein from the hyperthermophile Thermococcus thioreducens sp. nov., strain $OGL-20P^T$, which was collected from the wall of the hydrothermal black smoker in the Rainbow Vent along the mid-Atlantic ridge. This protein, which has no detectable sequence homology with proteins or domains of known function, has a calculated pI of 4.76 and a molecular mass of 8.2 kDa. We report here the backbone $^1H$, $^{15}N$, and $^{13}C$ resonance assignments of $OGL-20P^T$-358. Assignments are 97.5% (316/324) complete. Chemical shift index was used to determine the secondary structure of the protein, which appears to consist of primarily ${\alpha}$-helical regions. This work is the foundation for future studies to determine the three-dimensional solution structure of the protein.

• Korean Institute of Interior Design Journal
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• no.21
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• pp.3-9
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• 1999

Contemporary society that is apt to be homogeneity because of the development of computer communication and mass-media desires to seek its own identity in native realm. Contemporary Korean architecture has endeavored continuous discussion and practice to keep its identity within the current tendency. The purpose of this study is to grope the alternative for genuine 'Koreaness' to analyse the variant trend of its characteristics 1990's. The variation of Korean society in 1990's that emphasize self-regulation and individual value has influence on the realm of architecture so much. The cognition of 'Koreaness' has changed with center in the individual and small -size design group, not present accommodation of past, but continuous research to find archetype of tradition which can play a decisive role of linking present and future on the foundation of past. Many attempts and practical works that express 'Koreaness' in 1990's are performed in the area of residence works that reflect Korean emotion and life-style directly. This change can be an answer to solve the problem of peculiarity and universality in 'Koreaness'. After 1960's the main theme of 'Koreaness' was traditional architecture form, but because of the induction of Postmodernism and at once its reflection and critical attitude with limit of formal duplication, which lost its meaning. In 1990's, research for spatial form as korean emotion and image has carried out and played an important part of original expression for 'Koreaness'

• Korean Security Journal
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• no.6
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• pp.195-213
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• 2003

This is a case study on the violent collective activities of spectators in professional soccer games. The purpose of this study is to examine the reasons and the processes of the activities. In order to achieve the purpose well, I analyzed two cases of violent collective activities in spectators of professional soccer games that were held on June 24 and July 28 in 2001. The data for this study was collected from 14 kinds of daily newspapers from June 10 to August 20 in 2001 to maintain the objective validity of the outline, the reasons, and the processes of the violent collective activities of spectators in two cases. The data was collected from Korea Integrated News Database System(KINDS) of Korea Press Foundation, and Chollian, on-line service of DACOM, for its efficiency, accuracy and promptness. On the basis of the above-mentioned method as well as the consequences of data analysis, I've reached to a conclusion as follows. The reasons of the violent collective activities of spectators in professional soccer games were the mass effect, the activities of players, umpires and the results of games, etc. The violent collective activities of spectators in professional soccer games need pre-requirements and have relationships with special affairs that are developed in a regular sequence. In other words, a collective activity gives an effect on another one directly or indirectly. Therefore, this study shows that we can reduce or prevent the damages by the violent collective activities of spectators in sport games when we analyze the processes of collective activities and make a previous counter-measure for that.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2009.04a
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• pp.315-318
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• 2009

본 논문에서는 해상 기초 교각 매스 콘크리트의 수화열 저감 방안을 다루었다. 저발열 콘크리트, Mesh형 거푸집 공법 등에 대한 실험을 수행하여 각각의 수화열 저감효과를 평가하였다. 현장 실험은 사용 시멘트와 거푸집의 종류, 거푸집의 사용 면수에 따라 총 4 type으로 구성하였으며, 이에 대한 실험 결과와 유한 요소 해석 결과를 비교, 검증하여 최종적인 수화열 저감 성능을 도출하고자 하였다. 실험을 통해, 저발열 시멘트와 유로폼을 사용하는 것이 수화열 저감을 위해 효과적인 방법으로 판명되었으나 추가 공사비의 발생으로 효율성이 떨어질 것으로 판단된다. 또한 Mesh형 거푸집 적용 면 수와 온도 상승 저감 효과는 비례하는 것을 알 수 있었지만 내 외부 온도차가 다소 크게 나타나 수화열에 의한 균열 발생 확률면에서는 다소 불리하게 나타났다. 그러나 실험 단계에서 생략된 양생과 관리를 통하여 균열의 저감효과를 거둘 수 있을 것으로 판단되며, 추가적으로 거푸집 해체 단계를 생략함으로 공기단축 측면에서 유리할 것으로 판단된다.

• Structural Engineering and Mechanics
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• v.66 no.5
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• pp.637-648
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• 2018

When the centers of mass and stiffness of a building do not coincide, the structure experiences torsional responses. Such systems can consist of the underlying soil and the super-structure. The underlying soil may modify the earthquake input motion and change structural responses. Specific effects of the input motion shall also not be ignored. In this study, seismic demands of asymmetric buildings considering soil-structure interaction (SSI) under near-fault ground motions are evaluated. The building is modeled as an idealized single-story structure. The soil beneath the building is modeled by non-linear finite elements in the two states of loose and dense sands both compared with the fixed-base state. The infinite boundary conditions are modelled using viscous boundary elements. The effects of traditional and yield displacement-based (YDB) approaches of strength and stiffness distributions are considered on seismic demands. In the YDB approach, the stiffness considered in seismic design depends on the strength. The results show that the decrease in the base shear considering soft soil induced SSI when the YDB approach is assumed results only in the center of rigidity to control torsional responses. However, for fixed-base structures and those on dense soils both centers of strength and rigidity are controlling.

• Journal of Information Technology Applications and Management
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• v.11 no.2
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• pp.29-43
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• 2004

As the development of an information technique, gradually, mobile device is going to be miniaturized and operates at high speed. By such the requirements, the devices using a flash memory as a storage media are increasing. The flash memory consumes low power, is a small size, and has a fast access time like the main memory. But the flash memory must erase for recording and the erase cycle is limited. JFFS is a representative filesystem which reflects the characteristics of the flash memory. JFFS to be consisted of LSF structure, writes new data to the flash memory in sequential, which is not related to a file size. Mounting a filesystem or an error recovery is achieved through the sequential approach. Therefore, the mounting delay time is happened according to the file system size. This paper proposes a MJFFS to use a multi-checkpoint information to manage a mass flash file system efficiently. A MJFFS, which improves JFFS, divides a flash memory into the block for suitable to the block device, and stores file information of a checkpoint structure at fixed interval. Therefore mounting and error recovery processing reduce efficiently a number of filesystem access by collecting a smaller checkpoint information than capacity of actual files. A MJFFS will be suitable to a mobile device owing to accomplish fast mounting and error recovery using advantage of log foundation filesystem and overcoming defect of JFFS.