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Predictive maintenance technology for smart factory (스마트 팩토리를 위한 예지보전 기술)

  • Kwon, Dae-hoon;Oh, Chang-heon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2021.05a
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    • pp.172-174
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    • 2021
  • In the existing industry, maintenance was carried out in the form of preventive maintenance such as occurrence of unnecessary idle time due to limited monitoring and maintenance. However, with the advent of the Fourth Industrial Revolution, real-time monitoring is possible in many industries including mining, manufacturing, oil and gas, and commercial agriculture, and it is desired to minimize idle time due to maintenance. In particular, there is a growing interest in predictive maintenance that can reduce costs and maximize operational efficiency by predicting and maintaining a failure before equipment and equipment fail. In this study, we look at the predictive maintenance technology that can verify the abnormal condition of the equipment of the smart factory in advance and monitor the abnormal condition in real time.

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Preparation and Evaluation of Ketoconazole-loaded Solid-SNEDDS (Self-Nanoemulsifying Drug Delivery System) using Various Solidification Carriers (다양한 분말화 담체를 이용한 케토코나졸 함유 자가미세유화약물전달시스템의 제조 및 평가)

  • Da Young Song;Kyeong Soo Kim
    • Journal of Powder Materials
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    • v.30 no.6
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    • pp.493-501
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    • 2023
  • This study aimed to develop a solid self-nanoemulsifying drug delivery system (solid-SNEDDS) to enhance the formulation of ketoconazole (KTZ), a BCS Class II drug with poor solubility. Ketoconazole, which is insoluble above pH 3, requires solubilization for effective delivery. This SNEDDS comprises oil, surfactant, and co-surfactant, which spontaneously emulsify in the gastrointestinal tract environment to form nanoemulsions with droplet sizes less than 100 nm. The optimal SNE-vehicle composition of oleic acid, TPGS, and PEG 400 at a 10:80:10 weight ratio was determined based on the smallest droplet size achieved. This composition was used to prepare liquid SNEDDS containing ketoconazole. The droplet size and polydispersity index (PDI) of the resulting liquid SNEDDS were analyzed. Subsequently, solid-SNEDDS was fabricated using a spray-drying method with solidifying carriers such as silicon dioxide, crospovidone, and magnesium alumetasilicate. The physicochemical properties of the solid-SNEDDS were characterized by scanning electron microscopy and powder X-ray diffraction, and its solubility, droplet size, and PDI were evaluated. In particular, the solid-SNEDDS containing ketoconazole and crospovidone in a 2:1 weight ratio exhibited significantly enhanced solubility, highlighting its potential for improved medication adherence and dissolution rates.

Aromatherapy Interventions for the Elderly: A Review of Research Trends and Methodologies in Korea

  • SunHwa Park;Mi-Hwa Kim;Mi-Seon Kim;Jin Lee
    • International Journal of Advanced Culture Technology
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    • v.11 no.4
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    • pp.62-73
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    • 2023
  • This study aims to identify research trends and explore the latest methods of applying aromatherapy to the elderly. The main objective is to provide evidence in support of development of an aromatherapy nursing intervention program for the elderly. This investigation is in the form of a literature review focusing on the current status and trends in research conducted on aromatherapy intervention programs for the elderly in Korea over past decade. Published studies were identified through database such as KCI, RISS, DBpia, NDSL. A total 14 studies were selected for this review. The majority of selected articles fall within the field of nursing. The duration of the programs varied, ranging from less than 20 minutes to over 40 minutes, and consisted of 1 to 6 sessions. Most of methods involved massages using lavender oil in a hospital setting. Outcome variables were categorized into three main domains based on significance: psychological-emotional, interpersonal relationship, and physical-physiological. The variables within each category varied with 4 in psychological-emotional, 1 in interpersonal relationship, and 17 in physical-physiological. This review indicates that aromatherapy intervention programs have positive effects on the elderly and suggests the potential for developing similar interventions on a broader scale within community settings in the future.

Effect of Water on Lecithin/Bile/Decane Organogels (레시틴/담즙염/데케인 유기젤에 대한 물의 영향)

  • Eun-ae Chu;Na-hyeon Kim;Min-seok Kang;Kyo-chan Koo;Hee-Young Lee
    • Journal of Adhesion and Interface
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    • v.24 no.4
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    • pp.131-135
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    • 2023
  • Lecithin self-assembles into reverse spherical micelles in organic solvents as an amphiphilic molecule. When additives such as bile salts and water are introduced into lecithin solutions, it induces structural changes in the molecular form of lecithin, leading to the transformation into reverse cylindrical micelles. In this study, we observe the rheological changes of lecithin/bile salt mixtures in a decane system after the addition of water. The resulting mixtures exhibit high viscosity and characteristics of viscoelasticity, suggesting potential applications in various fields such as drug delivery and edible oil gels.

The Effects of Ethanol on Nano-emulsion Prepared by High-energy Emulsification Method (고에너지유화법을 이용하여 제조한 나노에멀젼에 대한 에탄올의 영향)

  • Won, Bo-Ryoung;Park, Soo-Nam
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.35 no.3
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    • pp.179-191
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    • 2009
  • The objective of this study was to investigate the effect of ethanol on the emulsion prepared by poly(oxyethylene) hydrogenated castor oils (HCOs)/oil/ethanol/water system. Emulsions were prepared using homogenizer as high-energy method. To evaluate effect of ethanol on the emulsion, physical properties such as droplet size and size distribution were determined and other components were almost fixed to analyze the effect of ethanol on the surfactant. In case of HCO-20, the droplet diameter was in micrometers and the droplet size was gradually deceased as the ethanol concentration was increased. The droplet diameter of nano-emulsion containing 4.00 % of HCO-30 was shown in nanometers and its mean droplet size was $128.15{\pm}1.06nm$ and the most stable at the 4.25 % of ethanol contents by the Form. 1 and $136.10{\pm}0.99nm$ at the 3.50 % of ethanol contents by the Form. 2. Similarly, the droplet diameter of nano-emulsion containing 4.00 % of HCO-40 and 4.50 % ethanol by the Form. 1 was $115.85{\pm}0.78nm$ and $121.15{\pm}0.35nm$ at the 3.25 % of ethanol by the Form. 2 and both size distributions were also narrow. Finally, the droplet size of nano-emulsion containing 4.00 % of HCO-60 and 2.25 % ethanol was $262.35{\pm}0.64nm$ and the most stable. The higher ethanol concentrations became the smaller size of emulsion became in the microscale emulsion but we determined nano-emulsion had a minimum size at a certain ethanol concentration. The results showed that the breakdown process of this nano-emulsion could be attributed to Ostwald ripening. This study about effect of ethanol on the emulsion showed that ethanol contents to prepare a stable emulsion could be determined as studying the effect of ethanol on the emulsion with the type of surfactants.

A Case Study on the Limitations of the Choice of Law caused by Internationally Mandatory Rules in Entering into the Turn-Key Contracts (턴키계약체결시 국제적 강행규정에 의한 준거법 제한에 관한 사례연구 - Clough Engineering Ltd v Oil & Natural Gas Corp Ltd 사건을 중심으로 -)

  • Oh, Won-Suk;Kim, Yong-Il
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.54
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    • pp.145-166
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    • 2012
  • This article examines the limitations of the choice of law caused by Internationally Mandatory Rules in Entering into the Turn-Key Contracts. In June 2007, Clough Engineering, a corporation based in Western Australia, approached the Federal Court of Australia seeking injunctive relief and leave to commence proceedings against an entity located outside Australia, the Oil & Natural Gas Corp of India (ONGC). Clough had contracted with ONGC to provide a range of services in relation to the construction of gas and oil wells off the coast of India. The contract was governed by Indian law, and included a clause by which the parties agreed to submit their disputes to arbitration. Yet the Federal Court assumed jurisdiction over the dispute, principally because Clough had framed its claim as a plea for relief for contraventions of Australia's Trade Practices Act 1974. The result of this cases that it is possible for an arbitral tribunal to hear a claim made under the Trade Practices Act even if that claim arises "in connection with"a contract the proper law of which is not the law of Australia. However, in Transfield Philippines Inc v Pacific Hydro Ltd, the turnkey contract included a choice of law provision, selecting the law of the Philippines, and a clause providing that all disputes arising out of or in connection with the agreement were to be arbitrated under the ICC Rules, with the seat in Singapore. Hearings were in fact conducted in Melbourne, Australia, although all awards were published in Singapore. The result of this cases that it would not be appropriate for an Australian court to adjudicate claims for misrepresentation under Australian statutes dealing with misleading and deceptive conduct, once the arbitral tribunal had determined, applying appropriate choice of law rules, that such claims are governed by the law of the Philippines. To do so would lead to a multiplicity of proceedings, usurp the jurisdiction of the tribunal and deny the intention of the parties as expressed by them in the arbitration agreement. In short, the Internationally Mandatory Rules as an active part of public order create limitation of party autonomy in choice of law rules in a different way. The court is fully entitled to refuse to use those rules of law applicable on the contract which are in the contradiction to the internationally mandatory rules of law of the forum. And the court may give an effect to those Internationally Mandatory Rules that form a part of a law of foreign country when deciding about applicability of certain rules of applicable law.

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Development of Lubricating Oil Additives. Synthesis of Polyisobutenylsuccinic Anhydride (윤활유 첨가제의 개발. Polyisobutenylsuccinic Anhydride의 합성)

  • Kim, Taek Hyeon;Jeong, Chan Ho
    • Applied Chemistry for Engineering
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    • v.8 no.3
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    • pp.425-429
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    • 1997
  • Polyisobutenylsuccinic anhydride(PIBSA), an intermediate for the lubricating oil additive, was prepared by the reaction of polyisobutylene(PIB) with maleic anhydride (MA). The functionality, which indicates the extent of reaction of PIB-a and MA, was determined in the various reaction conditions : fuctionality was 0.98 under the reaction conditions of no solvent for 12 hours at $190^{\circ}C$, 0.21 in benzyl alcohol solvent for 12 hours at $190^{\circ}C$, and 0.03~0.20 with various Lewis acids such as $AlCl_3$, $SnCl_4$, $Et_2AlCl$, and $TiCl_4$. The fuctionality also depended on the structure of PIBs. As ${\alpha}$-olefin content (exo-form) in PIB increased, the fuctionality had a higher value. The structure of PIBSA prepared from PIB and MA was determined with FT IR and $^1H$ NMR spectroscopy. Two strong anhydride IR bands at 1782 and $1855cm^{-1}$ were obserbed and two IR bands at 1639 and $897cm^{-1}$ for unsaturated groups of PIB disappeared. The presence of the anhydride was difficult to find by $^1H$ NMR spectroscopy because the anhydride protons gave relatively small peaks over a 2.0~3.0 range. Polyisobutenylsccinimide (PIBSI), a lublicating oil additive, was prepared by the reaction of PIBSA with diaminoethane.

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A Study on the Marine Environmental Protection of Northeast Asian Seas in International Law (국제법상 동북아해저환경보존에 관한 연구)

  • 이윤철
    • Journal of the Korean Institute of Navigation
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    • v.19 no.2
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    • pp.77-97
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    • 1995
  • The protection of the marine environment is one of the main international legal problems in recent years. In parallel with the industrial development, a great quantity of chemical materials were used and in consequence, mass transportation of oil and other dangerous materials was required on the one hand, and discharge of industrial wasters drew also the attention on the other hand. Furthermore, oil tankers accidents, mass use of nuclear materials, sea-bed exploration and exploitation stimulated further deep human concern on the marine environment. The expansion of international concern to new and more dangerous sources of marine pollution regarded more strict and legal control on the Oil Tanker(DWT 95, 000tons, Cb=0.805) model. Calculation results are compared to the international, especially regional level. In particular, this study is concerned with the preservation of the Northeast Asian Seas surrounded by Japan, the Russian Far East, South Korea, North Korea, China and Taiwan. These adjacent countries must intensify cooperation regarding the prevention, reduction and control of the contamination of the sea. And this cooperation between the States concerned should, as much as possible, be aimed at maximizing the effectiveness of measures to prevent or abate transboundary environmental pollution. To achieve this purpose, States concerned should be imposed upon duties such as duty to assess the environmental impact, duty to inform, duty to consult and duty to assist on the basis of general principle of international law, international customary law and other various resolutions of international bodies. Depending on the nature and extent of actual or potential transboundary pollution with the use of a natural resource or the environment in general the establishment of some form of institutionalized cooperation between the States concerned may become useful or indispensable. The functions of this Organization are, inter alia, to keep the implementation of the Convention and the protocals under continuous observation, to make recommendations on regional or sub-regional rules and standards to be elaborated and on measures to be taken by the Contracting Parties, to be notified of any grave and imminent danger from pollution or threat of pollution by the Contracting Parties and to promote in close cooperation with appropriate governmental bodies additional measures to protect the marine environment of the Northeast Asian Seas, and so on. Above mentioned countries, first of all, are located within the Northeast Asian Seas geographically and, therefore, take responsibilities of preserving the clean sea against marine interferences regardless of any difference of the social, political and economic systems. They must be followed under the UNCLOS and other marine conventions. Under the present circumstances, Northeast Asian Seas will become dead seas in case that there is no instant and prompt action against pollution. Hence we have an absolute obligation to promote the development of the mandatory international environmental law, which in turn can faciliate more effective implementation of the regional cooperation by the neighbouring states within this area.

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Antioxidative Effectiveness of Water Extract and Ether Extract in Wormwood(Artemisia montana Pampan) (쑥(산쑥)의 물 추출물과 에테르 추출물의 항산화 효과)

  • Lee, Gee-Dong;Kim, Jeong-Sook;Bae, Jae-Oh;Yoon, Hyung-Sik
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.21 no.1
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    • pp.17-22
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    • 1992
  • Water extract, and free-, ester- and insoluble phenolic acids were extracted from wormwoods. The extracts were then dissolved in equal amounts of an edible soybean oil, and the resulting substrates, portion of the soybean oil (control), 0.02% BHA and 0.02% BHT were stored in incubator at $45^{\circ}C{\pm}1.0^{\circ}C$ for 32days. Peroxide values (POV) and thiobarbituric acid (TBA) values of control and the substrates were determined during th9 storage period. The POV of control, BHA, BHT and six substrates which were contained water extracts 0.5%, 1% and 1.5%, and free-, ester- and insoluble phenolic acids after 24days of storage were 77, 43, 17, 38, 26, 34, 45, 28 and 16m mole/kg oil respectively, The TBA values after 32days of storage were 0.278, 0.170, 0.070, 0.200, 0.178, 0.235, 0.167, 0.136, 0.062, respectively, It was found that the antioxidant activity in water extracts was highest in water 1 (the substrates containing water extracts 1%). It was also found that antioxidant activities in the phenolic acids were decreased in the following order ; insoluble phenolic acids>ester form>free phenolic acids. The phenolic acids separated and tentatively identified by Gas chromatography were catechol, vanillin, umbelliferone, p-coumaric acid, ferulic acid caffeic acid, protocatechuic acid, p-hydroxy benzoic acid and syringic acid.

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Antioxidative Effectiveness of Methanol Extract in Mustard (겨자(Brassica juncea) Methanol 추출물의 항산화 효과)

  • Choi, Kyoo Hong;Yoon, Hyung Sik;Kim, Jeong Sook
    • Current Research on Agriculture and Life Sciences
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    • v.7
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    • pp.165-174
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    • 1989
  • In this study, antioxidative effectiveness of BHA, BHT of 0.02% was compared to that of separated phenolic acid, ester form and insoluble phenolic acid were extracted from 50g mustard seed removed fat antioxidative effectiveness was assumed, measuring Peroxide value, TBA value for 5 days, storaging respective substrate and contrast tube at $45{\pm}1^{\circ}C$ for 25 days. 1. Laboratory tube was added by BHA, BHT separated phenolic acid ester form and insoluble phenolic acid extract and peroxide value of contrast tube after 25 days storage were 31.9, 13.2, 16.6, 11.2, 35.91. On the other hand at the same condition TBA of each antioxidativity matter were 0.24, 0.16, 0.19, 0.17, 027, 0.35 as a result remarkably appeared antioxidative effectiveness in meal soybean oil substrate. 2. Total phenolic contents of free phenolic acid and insoluble phenolic acid in mustard were 13.2mg/10ml, 340.5mg/10ml, 2.1mg/10ml. 3. Phenolic acid separated and identificated were catechol, methylcatechol, salicylic acid, cinnamic acid, p-hydroxybenzoic acid, syringic acid, caffeic acid, sinapic acid.

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