• Journal of Digital Convergence
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• v.19 no.10
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• pp.21-28
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• 2021

This study examines factors affecting correction officer's preference toward institute for forensic psychiatric. The data were collected from the correction officers who worked at the six correctional facilities in 2019. Binary logistic regression was used to find the factors on the officer's preference. The result showed that the correction officers had their own preference toward prison for forensic psychiatric, and the preference was positively related to the age of the officer, work experience at the mental health center, mentally-ill prisoner's fighting as the rule-violation in prison, refusal of medical treatment, and lack of laws and regulations for the mentally-ill prisoners. In contrast, there was a negative relationship between the officer's rank and the preference for forensic psychiatric. More work needs to be done in the future research to collect more samples and include a broader ranger of variables than now.

• The Korean Journal of Applied Statistics
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• v.23 no.1
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• pp.113-121
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• 2010

Mixture is that DNA profiles of samples contain material from more than one contributor, especially common in rape cases. In this situation, first, the method based on enumerating a complete set of possible genotype that may have generated the mixed DNA profile have been studied for interpreting DNA mixtures. More recently, the methods utilizing peak area information to calculate likelihood ratios have been suggested. This study is concerned with the analysis and interpretation of mixed forensic stains using quantitative peak area information and the method of forensic inference for extension of material from more than or equal to three contributors. Finally, the numerical example will be outlined.

• Korean Journal of Pharmacognosy
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• v.52 no.2
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• pp.69-76
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• 2021

Cannabis sativa is an important industrial plant utilized to produce fiber, oil, and medicinal ingredients. A chemotype of cannabis is divided into "Drug type" with predominance of tetrahydrocannabinolic acid (THCA) and "Fiber type" with cannabidiolic acid (CBDA). To develop molecular markers for the discrimination of these two types, nucleotide sequences of THCA synthase and CBDA synthase as well as their pseudogenes were retrieved from the recently published cannabis genome in chromosome scale. Gene-specific SNPs were discovered by multiple alignment of these sequences, and 2 dominant marker sets from each gene were designed for selective amplification. Our markers successfully identified "Drug type" and "Fiber type" cannabis plants as well as forensic samples including processed materials. Our molecular markers will provide a fast and efficient system for molecular-based identification of the cannabis plant.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.24 no.1
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• pp.107-122
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• 2014

The DDoS attacks and the APT attacks occurred by the zombie computers simultaneously attack target systems at a fixed time, caused social confusion. These attacks require many zombie computers running attacker's commands, and unknown malware that can bypass detecion of the anti-virus products is being executed in those computers. A that time, many methods have been proposed for the detection of unknown malware against the anti-virus products that are detected using the signature. This paper proposes a method of unknown malware detection using digital forensic techniques and describes the results of experiments carried out on various samples of malware and normal files.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.50 no.6
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• pp.806-811
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• 2017

A multiplex PCR system comprising 14 microsatellite markers was developed for genotyping analysis of the sea cucumber Stichopus japonicus. A total of 286 samples were used to evaluate genetic polymorphisms and forensic parameters of the microsatellite loci. In a single PCR reaction, all 14 loci were uniformly amplified and a total of 269 alleles were identified. The AJ19024 locus had the largest number of alleles (46), and its discriminatory power and exclusion power were 0.99 and 0.76, respectively. The fewest alleles (8) were present at the Psj2575 locus, which provided the lowest discriminatory power (0.81) and exclusion power (0.20). The mean number of alleles, mean heterozygosity, mean discrimination power and mean exclusion power per locus were 19.21, 0.70, 0.93, and 0.46, respectively. The combined matching probability for the 14 loci was $9.64{\times}10^{-19}$, and the combined power of exclusion was 0.999995. Thus, the forensic parameters evaluated in the present study demonstrated the utility of our multiplex PCR system for biological tracing methods, such as individual identification and paternity testing, in the sea cucumber.

• Analytical Science and Technology
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• v.33 no.2
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• pp.86-97
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• 2020

Reconstruction and separation of explosive-contaminated overlapping fingerprints constitutes an analytical challenge of high significance in forensic sciences. Laser-induced breakdown spectroscopy (LIBS) allows real-time chemical mapping by detecting the light emissions from laser-induced plasma and can offer powerful means of fingerprint classification based on the chemical components of the sample. During recent years LIBS has been studied one of the spectroscopic techniques with larger capability for forensic sciences. However, despite of the great sensitivity, LIBS suffers from a limited detection due to difficulties in reconstruction of overlapping fingerprints. Here, the authors propose a simple, yet effective, method of using chemical mapping to separate and reconstruct the explosive-contaminated, overlapping fingerprints. A Q-switched Nd:YAG laser system (1064 nm), which allows the laser beam diameter and the area of the ablated crater to be controlled, was used to analyze the chemical compositions of eight samples of explosive-contaminated fingerprints (featuring two sample explosive and four individuals) via the LIBS. Then, the chemical validations were further performed by applying the Raman spectroscopy. The results were subjected to principal component and partial least-squares multivariate analyses, and showed the classification of contaminated fingerprints at higher than 91% accuracy. Robustness and sensitivity tests indicate that the novel method used here is effective for separating and reconstructing the overlapping fingerprints with explosive trace.

• Analytical Science and Technology
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• v.32 no.3
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• pp.105-112
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• 2019

Fingerprints may be contaminated with ethanol solutions. In order to solve the case, the law enforcement agency may need to visualize the fingerprint from these samples, but the development method has not been studied. The paper with latent fingerprint was contaminated with ethanol solution and then the blurring of ridge detail was observed. As a result, when the copy paper was contaminated with ethanol solutions of less than 75 % (v/v), the amino acid components of latent fingerprint residue blurred but lipid components of latent fingerprint residue didn't blurred. On the other hand, when the paper was contaminated with ethanol solution of more than 80 % (v/v), the amino acid components of latent fingerprint didn't blurred but the lipid components of latent fingerprint blurred. Therefore, it is found that the paper contaminated with ethanol solutions of less than 75 % (v/v) should be treated by oil red O (ORO) enhancing lipid components, and the paper contaminated with ethanol solutions of 80 % (v/v) or more should be treated by 1,2-indandione/zinc (1,2-IND/Zn) enhancing amino acid components. The blurring of ridge detail was not observed when the fingerprints were deposited with fingers contaminated with ethanol solution. This fingerprints were treated with 1,2-IND/Zn or ORO to compare the latent fingerprint development ability, and using 1,2-IND/Zn was able to visualize the latent fingerprint more clearly than using ORO.

• Mass Spectrometry Letters
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• v.9 no.4
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• pp.95-99
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• 2018

An innovative, simple, and rapid assay method based on liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) was developed and validated for the simultaneous determination of eight statin drugs in human urine. A simple sample clean-up procedure using the "dilute and shoot" (DAS) approach enabled a fast and reliable analysis. The influence of the dilution factor was investigated to ensure detectability and reduce the matrix effect. Chromatographic separation was performed on a Phenomenex Kinetex C18 column ($50{\times}3.0mm$ i.d., $2.6{\mu}m$) using an elution gradient of mobile phase A composed of 0.1% acetic acid, and mobile phase B composed of acetonitrile, at a flow rate of 0.35 mL/min. Quantitation was performed on a triple quadrupole mass spectrometer operated in multiple reaction monitoring (MRM) mode using electrospray ionization in positive ion mode. The total chromatographic run time was 15 min. The method was validated for selectivity, sensitivity, recovery, linearity, accuracy, precision, and stability. The present method was successfully applied to the analysis of Rosuvastatin in urine samples after oral administration to healthy human subjects.

• Anatomy and Cell Biology
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• v.56 no.1
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• pp.54-60
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• 2023

Lactase non-persistence (LNP), one of the causes of lactose intolerance, is related to lactase gene associated single nucleotide polymorphisms (SNPs). Since the frequency of LNP varies by ethnic group and country, the research to reveal the presence or absence of LNP for specific people has been conducted worldwide. However, in East Asia, the study of lactase gene associated SNPs have not been sufficiently examined so far using ancient human specimens from archaeological sites. In our study of Joseon period human remains (n=14), we successfully revealed genetic information of lactase gene associated SNPs (rs1679771596, rs41525747, rs4988236, rs4988235, rs41380347, rs869051967, rs145946881 and rs182549), further confirming that as for eight SNPs, the pre-modern Korean people had a lactase non-persistent genotype. Our report contributes to the establishment of LNP associated SNP analysis technique that can be useful in forthcoming studies on human bones and mummy samples from East Asian archaeological sites.

• Parasites, Hosts and Diseases
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• v.54 no.5
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• pp.555-563
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• 2016

For several years, we have conducted a series of studies on the patterns of ancient parasitism prevailing in the soil of rural and urban areas of past Kingdom of Korea. Actually, during our survey of paleoparasitology in archaeological sites of Korean peninsula, numerous ancient parasite eggs were discovered in the samples from the city districts of Hansung (Joseon) and Buyeo (Baikje), the palace moat at Gyeongju (Silla), shell-midden site at Bonghwang-dong (Silla to Joseon), and the reservoir found in Hwawangsansung fortress (Silla). By the paleoparasitological studies, with respect to parasitism in the high-density populations of ancient towns and cities, we have managed to catch glimpses of the patterns prevalent therein: a serious parasitic contamination of the soil in ancient urban areas, but not in rural areas of the past. Our historical research also proposed the plausible mechanism of parasite infection very serious indeed among urban populations in Korean history. Although city dwelling doubtless has accrued significant benefits for people and populations with agriculture, it can be equally supposed that living in such highly populated areas might have facilitated the spread of parasite infection.