• 설비공학논문집
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• 제10권5호
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• pp.600-609
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• 1998

The experimental investigation of thermal response characteristics by the air flow through the porous media has been carried out. The packed spheres of steel or glass were considered as the porous media in the present study. Temperature distributions of the fluid in the porous media as well as pressure drops through the porous media were measured. The transient temperature variations in the porous media are compared favorably with the analytical results in the high Reynolds number ranges. However, in the low Reynolds number ranges, the experimental data deviate from the analytical results, due to the dominant heat conduction penetration to the upstream direction, which is not considered in the analytical model. The cool-down response of porous media is found to be dependent upon the specific dimensionless time considering the material property and air velocity. The heat discharge process is recommended to be operated until a certain time, considering the cost efficiency.

• Corrosion Science and Technology
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• 제6권1호
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• pp.18-23
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• 2007

DLC coatings have been deposited onto substrate of STS 316L and Ti alloy using r.f. PACVD (plasma-assisted chemical vapor deposition) with a mixture of $C_{6}H_{6}$ and $SiH_{4}$ as the process gases. Corrosion performance of DLC coatings was investigated by electrochemical techniques (potentiodynamic polarization test and electrochemical impedance spectroscopy) and surface analysis (scanning electron microscopy). The electrolyte used in this test was a 0.89% NaCl solution of pH 7.4 at temperature $37^{\circ}C$. The porosity and protective efficiency of DLC coatings were obtained using potentiodynamic polarization test. Moreover, the delamination area and volume fraction of water uptake of DLC coatings as a function of immersion time were calculated using electrochemical impedance spectroscopy. This study provides the reliable and quantitative data for assessment of the effect of substrate on corrosion performance of Si-DLC coatings. The results showed that Si-DLC coating on Ti alloy could improve corrosion resistance more than that on STS 316L in the simulated body fluid environment. This could be attributed to the formation of a dense and low-porosity coating, which impedes the penetration of water and ions.

• 센서학회지
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• 제32권6호
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• pp.418-424
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• 2023

Natural killer (NK) cells play a crucial role in combating infections and tumors. However, their therapeutic application in solid tumors is hindered by challenges, such as limited lifespan, tumor penetration, and delivery precision. Our research introduces a novel ultrasonic actuation technique to navigate NK cells more effectively in the vascular system, particularly at vessel bifurcations where targeted delivery is most problematic. We use a hemispherical ultrasonic transducer array that generates phase-modulated traveling waves, focusing on an ultrasound beam to steer NK cells using blood-flow dynamics and a focused acoustic field. This method enables the precise obstruction of non-target vessels and efficiently directs NK cells toward the tumor site. The simulation results offer insights into the behavior of NK cells under various conditions of cell size, radiation pressure, and fluid velocity, which inform the optimization of their trajectories and increase targeting efficiency. The experimental results demonstrate the feasibility of this ultrasonic approach for enhancing NK cell targeting, suggesting a potential leap forward in solid tumor immunotherapy. This study represents a significant step in NK cell therapeutic strategies, offering a viable solution to the existing limitations and promising enhancement of the efficacy of cancer treatments.

• 대한토목학회논문집
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• 제1권1호
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• pp.43-51
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• 1981

미생물(微生物)의 부착식(附着式) 성장(成長)을 이용(利用)한 폐수처리(廢水處理)의 이해(理解)를 돕기 위해 미생물막모형(微生物膜模型)을 정립(定立)하고 이의 simulation을 통하여 처리효율(處理効率)과 각종(各種) parameter 사이의 관계(關係)를 살펴보았다. 미생물막모형(微生物膜模型)은 기질(基質)의 침투정도(浸透程度)에 따라 두꺼운 막(膜)과 얇은 막(膜)으로 구분(區分)하고 각(各) 경우(境遇)에 대하여 미생물막내부(微生物膜內部)에서의 기질농도(基質濃度)와 flux를 산정(算定)할 수 있게 구성(構成)되어 있다. 모형(模型)의 정립과정(定立過程)에서 얻어진 무차원상수(無次元常數)인 ${\phi}_1$, ${\phi}_2$, 그리고 $\bar{S}_b$에 의해 기질농도(基質濃度)와 flux가 결정(決定)될 수 있음을 알았으며, ${\phi}_1$의 증가(增加)나 ${\phi}_2$의 감소(減少)에 의해 처리효율(處理効率)이 증가(增加)함을 알 수 있다. 또한 높은 처리효율(處理効率)을 유지(維持)하는 system은 모두 두꺼운 막(膜)에 속하는 것을 알 수 있다. 미생물막표면(微生物膜表面) 근처에서의 유속(流速)을 증가(增加)시킴으로써 두께가 일정(一定)한 막(膜)에 있어서 처리효율(處理効率)을 증가(增加)시킬 수 있다. 하지만 유속(流速)의 증가(增加)로 인해 sloughing이 많아져서 막(膜)의 두께가 감소(減少)하여 새로운 정상상태(定常狀態)로 바뀌게 된다. 현재(現在)까지 유속(流速)과 미생물막(微生物膜)두께사이의 관계(關係)가 정량적(定量的)으로 규명(糾明)되지 못하고 있으므로 새로운 정상상태(定常狀態)에서의 효율(効率)은 명백히 규정지을 수 없다.