• Nuclear Engineering and Technology
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• 제52권2호
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• pp.248-257
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• 2020

This study presents an initial design for a novel system consisting in a coupled nuclear reactor and a phase change material-based thermal energy storage (TES) component, which acts as a buffer and regulator of heat transfer between the primary and secondary loops. The goal of this concept is to enhance the capacity factor of nuclear power plants (NPPs) in the case of high integration of renewable energy sources into the electric grid. Hence, this system could support in elevating the economics of NPPs in current competitive markets, especially with subsidized solar and wind energy sources, and relatively low oil and gas prices. Furthermore, utilizing a prismatic-core advanced high temperature reactor (PAHTR) cooled by a molten salt with a high melting point, have the potential in increasing the system efficiency due to its high operating temperature, and providing the baseline requirements for coupling other process heat applications. The present research studies the neutronics and thermal hydraulics (TH) of the PAHTR as well as TH calculations for the TES which consists of 300 blocks with a total heat storage capacity of 150 MWd. SERPENT Monte Carlo and MCNP5 codes carried out the neutronics analysis of the PAHTR which is sized to have a 5-year refueling cycle and rated power of 300 MW_th. The PAHTR has 10 metric tons of heavy metal with 19.75 wt% enriched UO₂ TRISO fuel, a hot clean excess reactivity and shutdown margin of $33.70 and -$115.68; respectively, negative temperature feedback coefficients, and an axial flux peaking factor of 1.68. Star-CCM + code predicted the correct convective heat transfer coefficient variations for both the reactor and the storage. TH analysis results show that the flow in the primary loop (in the reactor and TES) remains in the developing mixed convection regime while it reaches a fully developed flow in the secondary loop.

• 한국가스학회지
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• 제27권2호
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• pp.57-64
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• 2023

가스계량기의 검침방식이 발전하면서 원격검침이 가능한 스마트 가스 계량기(누출점검용 계량기 및 다기능 안전 계량기)가 사용되고 있다. 이러한 계량기는 부가기능으로 수집하는 유량 및 압력 데이터를 활용하여 누출 판단을 하는 기능이 있다. 유량 데이터를 이용한 누출판단 기능은 실제 현장에서 유효한 사례가 있지만 압력 데이터 기반 누출 판단 기준은 누출로 인한 압력 값 변화뿐만 아니라 여러 요인(정압기 압력 크기, 인접 계량기 연계, 인접 주택 사용량, 계량기 위치 등)으로 압력 크기 변화(레벨)가 있는 문제점이 있다. 본 논문에서는 스마트 가스계량기에서 수집되는 압력데이터를 활용하여 누출여부를 판단 할 수 있는 기법으로 압력 데이터 전처리 방법과 누출 여부 관련 압력 값 범위 기준, 누출판단 기법 및 적용 사례 검증을 통해 개발하였다.

• 대한의용생체공학회:의공학회지
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• 제30권1호
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• pp.89-93
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• 2009

Bone remodeling is a continuous process of skeletal renewal during which bone formation is tightly coupled to bone resorption. Mechanical loading is an important regulator of bone formation and resorption. In recent studies, neurotransmitters such as vasoactive intestinal peptide (VIP) were found to be present inside bone tissue and have been suggested to potentially regulate bone remodeling. In this study, our objective was to use a pre-established in vitro oscillatory fluid flow-induced shear stress mechanical loading system to quantify the effect of VIP on bone resorptive activity and investigate its combined effect with mechanical loading. VIP decreased osteoclastogenesis significantly decreased RANKL/OPG mRNA ration by approximately 90%. Combined VIP and mechanical loading further decreased RANKL/OPG ratio to approximately 95%. These results suggest that VIP present in bone tissue may synergistically act with mechanical loading to regulate bone remodeling via suppression of bone resorptive activities.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2009년도 제40회 하계학술대회
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• pp.95_96
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• 2009

In this paper, a new algorithm of Integrated Volt/Var Control (IVVC) is proposed using Volt/Var control for the Distribution Automation System (DAS) based on the modeling of the distributed load and the distributed current. In the proposed, the load flow based on the modeling of the distributed load with Distributed Generation and the distributed current are estimated from constants of four terminals using the measurement of the current and power factor from a Feeder Remote Terminal Unit (FRTU). For Integrated Volt/Var Control (IVVC), the gradient method is applied to find optimal solution for tap and capacity control of OLTC (On-Load Tap Changers), SVR (Step Voltage Regulator), and SC (Shunt Condenser). What is more Volt/Var control method is proposed using moving the tie switch as well as IVVC algorithm using power utility control. In the case studies, the estimation and simulation network have been testified in Matlab Simulink.

• 전기학회논문지
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• 제58권8호
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• pp.1463-1471
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• 2009

In this paper, a new algorithm of Integrated Volt/Var Control (IVVC) is proposed using Volt/Var control for the Distribution Automation System (DAS) based on the modeling of the distributed load and the distributed current. In the proposed, the load flow based on the modeling of the distributed load and the distributed current are estimated from constants of four terminals using the measurement of the current and power factor from a Feeder Remote Terminal Unit (FRTU). For Integrated Volt/Var Control (IVVC), the gradient method is applied to find optimal solution for tap and capacity control of OLTC (On-Load Tap Changers), SVR (Step Voltage Regulator), and SC (Shunt Condenser). What is more Volt/Var control method is proposed using moving the tie switch as well as IVVC algorithm using power utility control. In the case studies, the estimation and simulation network have been testified in Matlab Simulink.

• Journal of Electrical Engineering and Technology
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• 제3권3호
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• pp.354-362
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• 2008

In this paper, a new algorithm of optimal voltage control is proposed for the Distribution Automation System (DAS) based on constants of four terminal network modeling. In the proposed method, the voltage profiles along feeders are estimated from the measurement of the current and power factor by a Feeder Remote Terminal Unit (FRTU) installed at each node. Whenever the voltage profile violates the restriction, the voltage control strategy is applied to keep the voltage levels along the feeders within the pre-specified range through the modification and coordination of the transformer under-load tap changers (ULTC), step voltage regulator (SVR), as well as shunt condenser. In the case studies, the estimation and control of the voltages have been testified in a radial distribution system with 11 nodes.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2003년도 춘계학술대회 논문집
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• pp.1294-1297
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• 2003

With the development of medical field, many kinds of operations have been performed on human articulation. Arthroscopic surgery, which has Irrigation Pumping System for security of operator vision and washing spaces of operation, has been used for more merits than others. In this paper, it is presented that the research on a reliable control algorithm of the pumping system instrument for arthroscopic surgery. Before clinical operation, the flexible artificial articulation model is used for realizing the model the most same as human's and the algorithm has been exploited for it. This system is considered of the following; limited sensing point, dynamic effect by compliance, time delay by fluid flow and so on. The system is composed with a pressure controller, a regulator for keeping air pressure, an airtight tank that can have distilled water packs, artificial articulation and a measuring system, and has controlled by the feedback of pressure sensor on the artificial articulation. Also the system has applied to Smith Predictor for time delay and the parameter estimation method for the most suitable system with both the experiment data and modeling. In this paper, the pressure error that is between an air pressure tank and an artificial articulation was measured so that the system could be presumed and then the controller had developed for performing State-Feedback. Finally, the controller with a real microprocessor has realized. The confidence of system can be proved by applying this control algorithm to an artificial articulation experiment material.

• Asian Pacific Journal of Cancer Prevention
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• 제15권5호
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• pp.2313-2318
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• 2014

Peroxisome proliferator-activated receptor gamma (PPAR-${\gamma}$), a ligand-dependent nuclear transcription factor, has been found to widely exist in tumor tissues and plays an important role in affecting tumor cell growth. In this study, we investigated the effect of PPAR-${\gamma}$ on aspects of the cervical cancer malignant phenotype, such as cell proliferation and apoptosis. Cell growth assay, Western blotting, Annexin V and flow cytometry analysis consistently showed that treatment with troglitazone (TGZ, a PPAR-${\gamma}$ agonist) led to dose-dependent inhibition of cervical cancer cell growth through apoptosis, whereas T0070907 (another PPAR-${\gamma}$ antagonist) had no effect on Hela cell proliferation and apoptosis. Furthermore, we also detected the protein expression of p53, p21 and Mdm2 to explain the underlying mechanism of PPAR-${\gamma}$ on cellular apoptosis. Our work, finally, demonstrated the existence of the TGZ-PPAR-${\gamma}$-p53 signaling pathway to be a critical regulator of cell apoptosis. These results suggested that PPAR-${\gamma}$ may be a potential therapeutic target for cervical cancer.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1998년도 추계학술대회
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• pp.127-128
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• 1998

It is necessary to maintain constant intravenous (IV) infusion rate. While infusion pump is able to control infusion rate with great accuracy, its rather large size and weight make it difficult for patients to move around. The most commonly used infusion device is gravity IV infusion set with its administration chamber being clamped according to the observed drip rate. In this case it may be easier and more accurate to maintain IV rate to given value if we automate the drip-counting process and tube-clamping work by electronic devices. We calculated volume infusion rate of specific fluid using optical drip rate meter which we had developed. To regulate fluid flow rate, we equipped the rate meter which we had developed with a miniaturized clamping apparatus using DC motor. Also, we Implemented drip detection and clamp control algorithm with PIC16C73 $\mu$-controller (Microchip). This system provides user interface through LCD display and key buttons.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2008년도 Proceedings of the Convention
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• pp.103-115
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• 2008

Hemodynamic shear stress, the dragging force generated by blood flow, is known as an anti-atherogenic factor. We tested whether lysyl-tRNA synthetase (KRS) will be utilized as an agent controlling shear-sensing systems. KRS was previously known to be secreted as a pro-inflammatory agent. Here we found that KRS inhibited various shear-stimulated signaling pathways. We further found that KRS binds to detergent-resistant membrane (DRM), indicating that KRS binding molecules exist in DRM, specialized regions of the plasma membrane. DRM plays important roles in a variety of cellular processes and consists of gangliosides, signaling molecules and cytoskeletons. We then determined that KRS was colocalized with integrins ${\alpha}4$, ${\alpha}5$ and $av{\beta}3$. In addition, KRS was shown to be associated with sialic acid, existing at the end of gangliosides. Interestingly, the adherent effect of KRS was inhibited by pretreatment with sialic acid. Moreover, treatment of endothelial cells with neuraminidase appeared to inhibit both the KRS adhesion to endothelial cells and shear-stimulated signaling. In conclusion, KRS is likely to be utilized as a vascular regulator.