• Journal of Yeungnam Medical Science
• /
• 제22권1호
• /
• pp.43-51
• /
• 2005

자궁경부 종괴형 자궁경부임신은 빠른 진단과 치료를 요하는 산과적 응급 상황으로 특징적인 초음파 및 MRI 소견을 정확하게 숙지하고 있어야 한다. 특징적인 초음파 소견으로는 혈중 ${\beta}$-HCG 수치가 상승되어 있는 환자에서 자궁경부의 확장, 심하게 불균일한 종괴, 색도플러 검사에서 강한 혈류, 영양막주위 혈류 양상 등이 있다. 특징적인 MRI 소견으로는 자궁경부의 종대, T2-강조영상에서 심하게 불균일한 혼합 신호강도, 가장자리의 저신호강도의 띠, 조기에 강하게 조영증강되는 결절성 부분 등이 있다.

• 대한의용생체공학회:의공학회지
• /
• 제42권1호
• /
• pp.25-30
• /
• 2021

Objective: The aim of this study is to consider the effect of skin tissue necrosis by improving blood flow in animal skin models for low frequency pulsed electromagnetic fields (LF_PEMF) stimulation. Methods: Twenty rats (Wistar EPM-1 male, 280-320 g) were randomly divided into control groups (n=10) and the PEMF groups (n=10). To induce necrosis of the skin tissue, skin flap was treated in the back of the rat, followed by isolation film and skin flap suturing. Subsequently, the degree of necrosis of the skin tissue was observed for 7 days. The control group did not perform any stimulation after the procedure. For the PEMF group, LF_PEMF (1 Hz, 10 mT) was stimulated in the skin flap area, for 30 minutes a day and 7 days. Cross-polarization images were acquired at the site and skin tissue necrosis patterns were analyzed. Results: In the control group, skin tissue necrosis progressed rapidly over time. In the PEMF group, skin tissue necrosis was slower than the control group. In particular, no further skin tissue necrosis progress on the day 6. Over time, a statistically significant difference from the continuous necrosis progression pattern in the control group was identified (p<0.05). Conclusions: It was confirmed that low frequency pulsed electromagnetic fields (LF_PEMF) stimulation can induce relaxation of skin tissue necrosis.

• The Korean Journal of Pain
• /
• 제22권1호
• /
• pp.52-57
• /
• 2009

Background: Transforaminal epidural injection (TEI) may be useful to treat unilateral pain that has a dermatomal distribution. In this approach, the needle tip can be placed closer to the dorsal root ganglion and ventral aspect of the nerve root. However many studies have reported that serious complications following TEI occurred more frequently when it was conducted at the cervical level. One of the presumptive mechanisms of the complication is intravascular injection. Therefore this study was conducted to identify the incidence of complications in response to intravascular injections at cervical segments. Methods: This study included all patients, who visited our pain clinic and had radicular symptoms or herpes zoster associated pain. All procedures were conducted under fluoroscopic guidance with contrast enhancement by one of the authors. After the ideal needle position was confirmed by biplanar fluoroscopy, the blood aspiration through the needle hub was evaluated, and a 3 ml mixture of nonionic contrast (2 ml) with normal saline (1 ml) was injected at a rate of 0.3-0.5 ml/sec continuously under real time fluoroscopic visualization. We then classified the contrast spreading pattern as neural, simultaneous neural and vascular, or vascular. Results: A total 71 cervical TEIs were performed. In 26 cases (36.6%), the contrast only spread to the nerve sheath. However, 45 cases (63.4%) showed an intravascular spreading pattern, 37 (52.1%) of which showed a neural and vascular pattern and 8 (11.3%) of which showed only a vascular pattern. Conclusions: Approximately two thirds of the cases of cervical TEI were found to lead to intravascular spreading, which is much higher than the incidence reported in previous studies.

• Nuclear Medicine and Molecular Imaging
• /
• 제43권2호
• /
• pp.107-111
• /
• 2009

목적: 저자 들은 주 우울증 환자들의 뇌 혈류 SPECT을 정상 대조군과 비교하여, 기존에 보고된 주 우울증 환자들의 소견과 어떤 차이가 있는 지 알아보고자 하였다. 대상과 방법: DSM-IV criteria로 주 우울증인 환자들 중에서 4주 이상 모든 정신과적 약물을 중지시킨 12명(남: 7, 녀: 5, 나이 범위: $19{\sim}52$세, 평균 나이: $29.3{\pm}9.9$세)과 자발적으로 지원한 정상 대조군 14명(남: 8, 녀: 6, 나이 범위: $19{\sim}53$세, 평균 나이: $31.4{\pm}9.2$세)을 대상으로 하였다. Tc-99m ECD 주사 후 SPECT 영상을 얻은 후, 주 우울증 환자군과 정상 대조군에서의 국소 뇌 혈류 패턴을 비교하였다. 결과: 정상인 대조군에 비해서, 주 우울증 환자들은 우측 후두엽의 설상 회와 방추상 회, 좌측 후두엽의 설상 회와 설전부, 그리고 좌측 측두엽의 상측두 회의 국소 뇌 혈류가 의미있게 증가하였다. 또한 우측 뇌교, 좌측 전두엽의 내측 전두회, 좌측 변연계의 대상 회, 우측 전두엽의 대상 회, 우측 변연계의 대상 회에서는 대조군에 비해 주 우울증 환자에서 국소 뇌 혈류가 의미있게 감소하였다. 결론: 주 우울증 환자군의 Tc-99m ECD뇌 혈류 SPECT 소견은 기존의 보고와 큰 차이가 없었으며, 우측 뇌교와 대상 회 그리고 좌측 내측 전두 회에서 특정적인 국소 뇌 혈류 감소 소견이 있었다.

• 제어로봇시스템학회:학술대회논문집
• /
• 제어로봇시스템학회 2001년도 ICCAS
• /
• pp.55.4-55
• /
• 2001

Analyzing the ECG signal, we can find heart disease. Myocardial ischemia is a disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. Myocardial ischemia is inscribed on ST-segment of the ECG during and after patient takes exercise or is under stress, but after long time past, the ECG pattern is return to steady state. Therefore, it is necessary to monitor and analyze the ECG signal continuously for patient or aged people. Our primary purpose is the detection of temporary change of the ST-segment of ECG automatically. In the signal processing, the wavelet transform decomposes the ECG signal into high and low frequency components using wavelet function. Recomposing the high frequency bands including QRS complex, we can detect QRS complex more easily ...

• 수면정신생리
• /
• 제1권2호
• /
• pp.193-196
• /
• 1994

Primary depression with cognitive impairment, referred to as depressive pseudodementia, may be mistaken for a progressive degenerative dementia. Recognition of primary depression is clinically important because of its treatability. To differentiate depression from degenerative dementia, author used brain SPECT. By the result the regional cerebral blood flow(rCBF) in elderly depressed patient was decreased in the right frontal cortex. The pattern of rCBF was different from that of dementia which shows decreased rCBF in bifrontal cortex. By using brain SPECT in depressed elderly patient with cognitive impairment, the discrimination from dementia will be more effective and accurate.

• 한국임상수의학회지
• /
• 제38권3호
• /
• pp.163-168
• /
• 2021

A 6-year-old, spayed female, Maltese dog with tachypnea and dry cough was presented to Gyeongsang National University Veterinary Medical Teaching hospital. On physical examination, its respiration rate was 132 per minute. Decreased partial pressure of oxygen, partial pressure of carbon dioxide, and hyperlactatemia were found on arterial blood gas analysis. Its diastolic blood pressure was 80 mmHg. Auscultation revealed arrhythmia. Electrocardiogram revealed P pulmonale, P mitrale, and ventricular premature complexes. Thoracic radiographs revealed mild enlargement of both atrium and moderate enlargement of the left ventricular. There was also a moderate alveolar pattern in the right and caudal part of the left cranial lung lobe. Two-dimensional echocardiography showed enlargement of generalized four chambers without remarkable findings of valvular degeneration. M-mode echocardiography showed decreased left ventricular fractional shortening and enlarged left ventricular internal diameter at both end-systolic and end-diastolic. Color-flow Doppler imaging revealed eccentric turbulent flow starting below the left ventricular outflow tract and extending into the left atrium during systole. Spectral Doppler recordings revealed a high velocity flow through the mitral, tricuspid, aorta, and pulmonic regurgitation. Restrictive transmitral flow revealed high E-wave velocity, short E-wave deceleration time, and reduced A-wave velocity. There was also low ejection velocity thorough left ventricular out tract flow. Based on echocardiographic examination, dilated cardiomyopathy was the tentative diagnosis. The dog was medicated with inotropes, angiotensin converting enzyme inhibitor, and diuretics. At the 10-day following-up, the dog died suddenly. This report describes echocardiographic diagnosis and prognosis of dilated cardiomyopathy rarely reported in small breed dogs.

• Journal of Ginseng Research
• /
• 제27권4호
• /
• pp.165-170
• /
• 2003

발기부전 환자에서 홍삼의 효능을 객관적으로 확인하기 위하여 홍삼 복용 전후의 음경혈류 변화를 AVS-Penogram을 이용하여 홍삼이 음경발기 및 음경혈류에 미치는 영향을 활성도 곡선의 유형 변화와 최대활성도치를 분석하여 평가하고, 동시에 주관적인 발기부전의 증상호전 정도를 비교하였다. 활성도 곡선유형은 홍삼 투여군에서 위약 투여군에 비하여 전반적으로 호전 양상을 보였으나 통계학적 유의성은 없었고, 최대활성도치의 증가에서는 홍삼 투여군이 57.9%(l1/19)로 위약 투여군의 22.2%(2/9)에 비하여 유의하게 높은 호전을 보였으며, 주관적인 증상호전에서도 홍삼 투여군이 63.2％(12/19)로 위약 투여군의 33.3%(3/9)에 비하여 유의한 호전을 나타냈다. 약물의 안정성 평가에서는 약물 관련 특이 반응이나 특별한 부작용은 없는 것으로 나타났다. 이상으로 발기부전 환자에서 홍삼의 투여가 특별한 독성이나 부작용 없이 위약군에 비하여 좋은 치료효과를 보이며, 음경발기와 음경혈류 증가에 양성적인 영향을 미치는 것으로 나타났으며, 단독 투여뿐만 아니라 다른 발기부전 치료제와의 병용 요법에 따른 상승효과(synergic effect) 등에 대하여도 인상 연구가 필요하리라 생각된다.

• Investigative Magnetic Resonance Imaging
• /
• 제18권4호
• /
• pp.314-322
• /
• 2014

배경: 심장의 이완기능 이상은 비대성심근증 환자에서 흔히 발견되는 문제이다. 본 연구는 비대성심근증 환자의 심장 이완기능을 평가하는 데 있어, 승모판과 폐정맥의 유속을 이용한 MRI의 역할을 알아보고자 하였다. 방법과 결과: 승모판과 폐정맥의 유속을 이용한 위상차 MRI와 심초음파검사가 59명 (남:여 = 44:15, 평균 연령 = 51세)의 비대성심근증 환자에서 시행되었다. 49명의 환자가 심초음파검사에서 다양한 정도의 심장 이완기능 이상을 보였다; grade 1 (20명), grade 2 (27명), and grade 3 (2명). MRI로 계산한 승모판 유속인자들 (E, A, E/A ratios)은 심초음파검사로 구한 동일 인자들과 양의 상관관계를 보였다 (Pearson's r values = 0.47, 0.60, 0.75 for E, A, E/A, respectively, all P < 0.001). MRI로 폐정맥 유속정보를 이용하는 경우, pseudo-normalized pattern (8명)이 정상 충만 양상(filling pattern) (17명)과 구분될 수 있었고, 이들을 이용하여 이완기능 정도를 평가를 하는 경우, 심장 MRI가 심초음파검사와 중등도의 일치도를 보였다 (kappa value = 0.45, P < 0.001). 결론: 비대성심근증 환자에서 위상차 MRI를 이용한 심장 이완기능 평가는 임상적으로 적용 가능한 방법이며, 폐정맥 유속 분석을 추가하는 경우, 정상과 pseudo-normal을 구분하는데 유용하다.

• 한국의사학회지
• /
• 제23권1호
• /
• pp.23-41
• /
• 2010

Greater yang disease(太陽病) is a syndrome induced by peripheral obstruction. One of them is "wind stroke(中風)" with the obstruction in lymphatic system. The other obstruction appearing on circulatory system is called "cold damage(傷寒)." Kyejitang(桂枝湯) is the formula prescribed for greater yang wind stroke pattern(太陽中風證) which is caused by peripheral lymphatic duct obstruction. Ramulus Cinamoni acts as a vasodilator and Radix Paeoniae relieves the abdominal tension. They make blood move to the internal organ and this can remove the retention of peripheral lymphatic system. Covering the patient with a blanket and getting him/her to have hot and thin rice gruel causes slight Diaphoresis, contributing to relieving the retention of lymphatic system. Disharmony between nutrient and defense(營衛不和) means that pressure becomes different between lymphatic system and vascular system. Kyejitang(桂枝湯) is called releasing muscles formula(解肌劑) because it can resolve such pressure difference. Diaphoresis is not a means to eliminate pathogenic qi(邪氣) from the body. That is the syndrome proving that the body fluid has moved around when disordered fluid distribution is corrected. Therefore, diaphoresis should be induced weakly all the time. If diaphoresis is induced excessively, body fluid will move more than desired and then illness cannot be cured. In Sanghanlun(傷寒論), dispersing drugs aim at addressing the retention in the exterior field, but it actually applies to the entire exterior and interior to make body fluid move. Therefore, diaphoresis does not just act on exterior field, and freeing the stool does not only apply to interior field. Distribution of body fluid changed by pathogenic qi(邪氣) influences the whole body because the human body has a closed circulatory system. Sanghanlun(傷寒論) has included treatments for pathogenic disease. However, its value should not be limited to pathogenic disease. It is because controlling blood flow by sending body fluid to the place a doctor wants is certainly worth using for treatment of non-exogenous disease or chronic illnesses.