• Journal of Korean Society of Industrial and Systems Engineering
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• v.1 no.1
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• pp.3-10
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• 1978

Human Engineering has an intention of design to keep the best condition of man-machine system. Hitherto the conception of design has been used to include existing engineering, as mechanical engineering and electric engineering. But the manufactured goods which to be made these process seem to be fully equipped on physical function, but faults come out discountent repeatedly to users. Accordingly, the development of industrial design has been demanded for improving functional design. It is considered that industrial design has aesthetical sensation. In actually, it must be 1. to provide for utility and safety, 2. easy for maintenance, 3. cheap at cost. 4. possible for sales appeal, 5. and good on appearance. As taking into consideration above five conditions, however, for 삯e sake of comprehend to human being about operating method of machinery and equipment, it should be reflected to design what kind of training way will be needed. Also, it must be considered what a certain extent would be occurred tiredness to human being. in other words. it should be considered the design to be possible the reflect to principle of motion economy, It should not be made adoption of human ability for the designed machinery, it must be adopted the method to consider the design on presuppose about human ability. For study of these actual fact, this paper is summarized the essence of human engineering, and also to find out the methodology as humanistic engineering, It is, Particularly, subdivisionization of operation in flow operation is essential direction of mechanization. Generally. as developing the subdivisionization of operation, it will be lack of satisfaction on operation which worker take charge of. The subdivisionization of operation makes the operation to simple-repetitive, to lose the interest of worker and will be also come into question to the feeling of worker's livelihood. It is human's fundamental desire to have get skilful function or special technique. But the subdivisionization of operation hold in those human's fundamental desire and so that it will likely to lose the sorority of living by this fact. Accordingly, this paper have an operation to hold out the methodology on presuppose about human ability.

• The Journal of Internal Korean Medicine
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• v.22 no.4
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• pp.675-681
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• 2001

Objectives : It was designed for making theoretical base about the relation of the Spleen, Stomach and the liver which could be used in clinic. Methods : Including Huang Di Nei Jing(黃帝內經), the 22 kinds of books written about the relation of the Spleen, Stomach and the Liver, and 2 kinds of papers were referenced. They were divided and studied according to physiology, pathology, meridian system and treatment. This study is focused on internal organ theory. Conclusion 1. In physiology, the Liver has the function of smoothing and regulating the flow of vital energy(Ki), while the Spleen is in charge of digestion and transportation. 2. In pathology, there can be informed disharmony of the Spleen, Stomach and the Liver, blood deficiency in the Liver and Spleen, jaundice, and bleeding etc. 3. In meridian system, the junction points of Spleen Meridian and Liver Meridian are Liv14, SP6, SP12, SP13. 4. In treatment, 1) If there is disharmony of the Liver and Spleen, the Liver must be soothed and the function of Spleen invigorated. 2) If there is disharmony of the Liver and Stomach, the Liver must be soothed and the function of Stomach invigorated.

• Asian-Australasian Journal of Animal Sciences
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• v.28 no.3
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• pp.420-427
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• 2015

It is necessary to understand the cellular uptake and cytotoxicity of food-grade delivery systems, such as ${\beta}$-lactoglobulin (${\beta}$-lg) nanoparticles, for the application of bioactive compounds to functional foods. The objectives of this study were to investigate the relationships between the physicochemical properties of ${\beta}$-lg nanoparticles, such as particle size and zeta-potential value, and their cellular uptakes and cytotoxicity in Caco-2 cells. Physicochemical properties of ${\beta}$-lg nanoparticles were evaluated using particle size analyzer. Flow cytometry and confocal laser scanning microscopy were used to investigate cellular uptake and cytotoxicity of ${\beta}$-lg nanoparticles. The ${\beta}$-lg nanoparticles with various particle sizes (98 to 192 nm) and zeta-potential values (-14.8 to -17.6 mV) were successfully formed. A decrease in heating temperature from $70^{\circ}C$ to $60^{\circ}C$ resulted in a decrease in the particle size and an increase in the zeta-potential value of ${\beta}$-lg nanoparticles. Non-cytotoxicity was observed in Caco-2 cells treated with ${\beta}$-lg nanoparticles. There was an increase in cellular uptake of ${\beta}$-lg nanoparticles with a decrease in particle size and an increase in zeta-potential value. Cellular uptake ${\beta}$-lg nanoparticles was negatively correlated with particle size and positively correlated with zeta-potential value. Therefore, these results suggest that the particle size and zeta-potential value of ${\beta}$-lg nanoparticles play an important role in the cellular uptake. The ${\beta}$-lg nanoparticles can be used as a delivery system in foods due to its high cellular uptake and non-cytotoxicity.

• Journal of Microbiology and Biotechnology
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• v.25 no.8
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• pp.1275-1280
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• 2015

Previously, we performed de novo RNA sequencing of Scolopendra subspinipes mutilans using high-throughput sequencing technology and identified several antimicrobial peptide candidates. Among them, a cationic antimicrobial peptide, scolopendrasin VII, was selected based on its physicochemical properties, such as length, charge, and isoelectric point. Here, we assessed the anticancer activities of scolopendrasin VII against U937 and Jurkat leukemia cell lines. The results showed that scolopendrasin VII decreased the viability of the leukemia cells in MTS assays. Furthermore, flow cytometric analysis and acridine orange/ethidium bromide staining revealed that scolopendrasin VII induced necrosis in the leukemia cells. Scolopendrasin VII-induced necrosis was mediated by specific interaction with phosphatidylserine, which is enriched in the membrane of cancer cells. Taken together, these data indicated that scolopendrasin VII induced necrotic cell death in leukemia cells, probably through interaction with phosphatidylserine. The results provide a useful anticancer peptide candidate and an efficient strategy for new anticancer peptide development.

• Journal of the Korea Society of Computer and Information
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• v.26 no.6
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• pp.167-172
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• 2021

The objective of this study is to present the academic implications and developmental direction of the police assigned for special guard system through big data analysis on the objective and macroscopic viewpoint of the media. As research method, this study conducted the analysis on 'police assigned for special guard' and the analysis of related words that would visualize the keywords highly related to keyword trend and news. Also, after dividing the period into the 1990s, 2000s, and 2010s, the number of relevant articles in each period was drawn for understanding the flow. In the results of this study, the perception of media report of police assigned for special guard was about the recruitment of police assigned for special guard, and relevant events/accidents, which showed the coexistence of positive interest in the recruitment of police assigned for special guard and negative image of events/accidents related to police assigned for special guard. As a result, however, the necessity and demand for police assigned for special guard are increasing. Thus, the police assigned for special guard should be engaged in work after carefully thinking of its role in charge of ethical responsibility and safety as an axis for maintaining the national safety and social order.

• Journal of The Korean Society of Agricultural Engineers
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• v.60 no.2
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• pp.25-36
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• 2018

Drip irrigation system is a low energy cost method which can efficiently save and supply water by dropping water slowly on the crop's root zone during crop growth. In the drip irrigation system, disk filters take an important role to physically remove impurity (inorganic and suspended organic) particles present in agricultural water which can cause emitter clogging. For the purpose, both top-and-bottom surfaces of the disk are grooved in micron size flowing from outside to inside. However, many congested flow paths in disk filter media incur higher head loss of inflow water resulting in relatively decreasing velocities depending on operation time than sand and mesh filters. Therefore, it is important to optimize the structure of disk filter in micro irrigation system. The head loss of disk filter media takes also charge of more than 60 % of total head loss in whole disk filter. This study is to find the appropriate cross-sectional shape of the disk groove to minimize the head loss by executing the experiment. The experiment used three disk filters that have similar filter body but have a half-elliptic and two kinds of triangular cross sections. The experimental results showed that the disk filter with half-elliptic cross sections of disk grooves have less head loss than the disk filter with regular triangular one.

• Journal of Korean Society of Environmental Engineers
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• v.35 no.11
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• pp.821-826
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• 2013

The purposes of this research are to study on optimal distance between positive and negative electrodes in dust removal chamber. The experiments were performed with electrode-plate gab arranging in order of 3 cm, 2 cm, 1 cm in series while varying influent flow-rate. From the experimental results of dust removal the optimal influent linear velocity was 6 cm/sec and the total mass of attached dust on the surface of electrode-plate was increased as electrode-plate gab is closer. But in case of electrode-plate gab being very close about 1 cm or so, the attached dust on the surface of electrode-plate was shown releasing from electrode-plate due to dust electric-charge changing (reverse ionization). Evantually. optimal distance between positive and negative electrode-plates was about 2 cm and also optimal dust loading rate was about $24mg/min{\cdot}m^2$.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.8 no.1
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• pp.1-12
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• 1996

In lots of application to heat exchanger systems, closed two-phase thermosyphons are tilted from a horizontal. If the tilt angle, especially, is less than 30$^{\circ}$, the operational performances of thermosyphon are highly dependent on tilt angle. The present study was conducted to better understand such operational behaviors as mech-anni는 of phase change, and flow patterns inside a tilted thermosyphon. For experiment, an ethanol thermosyphon with a 35% of fill charge rate was designed and manufactured, using a copper tube with a diameter 19mm and a length 1500mm. Through a series of test, the tilt angle was kept constant at each of 4 different values in the range 10~25deg. and the heat supply to the evaporator was stepwisely increased up to 30㎾/$m^2$. When a steady state was established to the thermosyphon for each step of thermal loads, the wall temperature distribution and vapor temperature at the condenser were measured. The wall temperature distributions demonstrated a formation of dry patch in the top end zone of the evaporator, with a values of temperature 20~4$0^{\circ}C$ higher than the wetted surface for a moderate heat flux q≒20㎾/$m^2$. Inspite of the presence of hot dry patch, however, the mean values of boiling heat transfer coefficient at the evaporator wall were still in a good agreement with those predicted by Rohsenow's formula, which was based on nucleate boiling. For the condenser, the wall temperatures were practically uniform, and the measured values of condensation heat transfer coefficient were 1.7 times higher than the predicted values obtained from Nusselt's film condensation theory on tilted plate. Using those two expressions, a correlation was formulated as a function of heat flux and tilt angle, to determine the total thermal resistance of a tilted thermosyphon. The correlation formula showed a good agreement with the experimental data within 20%.

• Korea Journal of Hospital Management
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• v.6 no.1
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• pp.1-17
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• 2001

According to the increase of the proportion of aged people, the medical demand for a senile chronic disease has been increased; therefore, aged people call for a geriatric hospital for special geriatric medical service. The main purpose of this study was to analyze the general characteristics and financial status of geriatric hospitals. For the study, a questionnaire was designed and sent to the geriatric hospitals to fill out the patient statistics, number of headcount by department, etc. to find out the stability, profitability, activity and so on financial statements of the hospitals were analyzed. The major findings of this study were as belows. 1. The ratio of the medical expenses to the revenue of the geriatric hospitals is much lower than acute care hospitals. But the probability of bankruptcy is higher due to the high ratio of the liabilities therefore it is required to stabilize the financial position by donating more money. 2. Government budget for the elderly people is not enough. To support the geriatric hospitals by going subsides, government should increase the budget. 3. Portion's of the patient of the geriatric hospitals are government support patient. Since the government doesn't pay the medical charges quickly, geriatric hospitals have a serious cash flow problem. Therefore, it is required that government is to prepay the bill. 4. Since geriatric hospitals treat elderly patient and most patients are government support patients, geriatric hospitals can be said to operate under the strict. 5. When we introduce the daily medical charge, the self-liability will be reduced on approximately 50% of current. This affection will bring a huge progressing financial structure to the medical profit of the geriatric hospital, and also patient family will feel less economical burden.

• Korean Chemical Engineering Research
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• v.48 no.6
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• pp.784-790
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• 2010

VOCs such as acetone, benzene, toluene, ethylbenzene were adsorbed in a fixed-bed adsorber using zeolite synthesized from coal fly ash and 4 kinds of activated carbon at 101.3 kPa. The adsorber was operated batchwise with the charge of 5 g adsorbent to obtain the breakthrough curve of VOCs. Experiments were carried out at $40^{\circ}C$, nitrogen flow rate of $70cm^3/min$ and sparger temperature of $30^{\circ}C$. The deactivation model was tested for these curves by combining the adsorption of VOCs and the deactivation of adsorbent particles. The observed values of the adsorption rate constant and the deactivation rate constant were evaluated through analysis of the experimental breakthrough data using a nonlinear least square technique. The experimental breakthrough data were fitted very well to the deactivation model than the adsorption isotherm models in the literature. Also, adsorption capacities of adsorbents were obtained from the breakthrough curve to observe the correlation between adsorption capacity and the physical properties of VOCs.