• Journal of the Korean Geotechnical Society
• /
• v.27 no.10
• /
• pp.93-104
• /
• 2011

In this paper, a numerical procedure of probabilistic steady seepage analysis that considers the spatial variability of soil permeability is presented. The procedure extends the deterministic analysis based on the finite element method to a probabilistic approach that accounts for the uncertainties and spatial variation of the soil permeability. Two-dimensional random fields are generated based on a Karhunen-Lo$\grave{e}$ve expansion in a fashion consistent with a specified marginal distribution function and an autocorrelation function. A Monte Carlo simulation is then used to determine the statistical response based on the random fields. A series of analyses were performed to verify the application potential of the proposed method and to study the effects of uncertainty due to the spatial heterogeneity on the seepage behavior of soil foundation beneath water retaining structure with a single sheet pile wall. The results showed that the probabilistic framework can be used to efficiently consider the various flow patterns caused by the spatial variability of the soil permeability in seepage assessment for a soil foundation beneath water retaining structures.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.38 no.4
• /
• pp.517-526
• /
• 2018

As groundwater recharge shows the heterogeneity in space and time due to land use and soil types, estimating daily recharge by integrated hydrologic analysis is needed. In this work, the SWAT-MODFLOW model was applied to compute daily based groundwater recharge in Jangseong region. The accuracy of the model was evaluated by comparing the observed and calculated values of the unsteady groundwater flow levels after calibrating the observed and calculated flow rates of the stream for a hydrological analysis. The estimated hydrologic components showed a strong correlation with each other and significant spatial variations regarding the groundwater recharge rate in accordance with the heterogeneous watershed characteristics such as subbasin slope, land use, and soil type. Overall, it was concluded that the coupled hydrologic models were capable of simulating the spatial variation with respect to the hydrologic component process in surface water and groundwater. The average recharge rate was estimated at approximately 20.8%.

• Geomechanics and Engineering
• /
• v.23 no.4
• /
• pp.327-338
• /
• 2020

The role of precise prediction of subsurface fluids and discrimination among them cannot be ignored in reservoir characterization and petroleum prospecting. A suitable rock physics model should be build for the extraction of valuable information form seismic data. The main intent of current work is to present a rock physics model to analyze the characteristics of seismic wave propagating through a cracked porous rock saturated by a three phase fluid. Furthermore, the influence on wave characteristics due to variation in saturation of water, oil and gas were also analyzed for oil and water as wet cases. With this approach the objective to explore wave attenuation and dispersion due to wave induce fluid flow (WIFF) at seismic and sub-seismic frequencies can be precisely achieved. We accomplished our proposed approach by using BISQ equations and by applying appropriate boundary conditions to incorporate heterogeneity due to saturation of three immiscible fluids forming a layered system. To authenticate the proposed methodology, we compared our results with White's mesoscopic theory and with the results obtained by using Biot's poroelastic relations. The outcomes reveals that, at low frequencies seismic wave characteristics are in good agreement with White's mesoscopic theory, however a slight increase in attenuation at seismic frequencies is because of the squirt flow. Moreover, our work crop up as a practical tool for the development of rock physical theories with the intention to identify and estimate properties of different fluids from seismic data.

• Journal of Korean Society for Geospatial Information Science
• /
• v.15 no.2 s.40
• /
• pp.33-42
• /
• 2007

A physical-based aggregation method was suggested to estimate surface roughness, which adequately represents the spatial heterogeneity of vegetation factors, from land cover property obtained from the remote sensing data. For the sensitivity analysis of surface roughness, the peak flow, peak time, and total volume were simulated by the NWS-PC. Effects of surface roughness estimated by three different integration methods (predominant, arithmetic mean, and aggregation approach) on the conceptual rainfall-runoff model parameters was analyzed. In the preliminary sensitivity test to surface roughness, the peak time had 10% variation and total volume had 2% variation. The peak time increased with surface roughness. A physical-based aggregation method was better than the existing method in the Soyanggang Dam basin for the results of STDEV, RMSE, NSE, and PME, but difference between them were small. The parameters related on the total baseflow were changed significantly with change of the surface roughness.

• Asian-Australasian Journal of Animal Sciences
• /
• v.15 no.2
• /
• pp.290-296
• /
• 2002

Serum immunoglobulins (Igs) from Israeli carp were purified using affinity chromatography. Fish were immunized with purified mouse IgG, and the specific fish antibodies were purified from the immune serum on a mouse IgG-immobilized agarose gel. Rabbit anti-Israeli carp Igs (R $\alpha$ I. carp Igs) antibodies were produced following hyperimmunization with mouse IgG specific carp antibodies. SDS-PAGE analysis under reducing condition showed that Israeli carp Igs were composed of two $\mu$-like heavy chains with about 82 and 50 kd, respectively, and one light chain with about 25 kd. On immunoblotting analysis, however, R $\alpha$ I. carp Igs failed to react with the light chain. When both protein A and protein G-purified normal carp Ig were compared with mouse IgG-specific Israeli carp Ig, no significant structural differences among them were observed. To investigate if there is any homology between other fish Ig molecules, cross-reactivity of R $\alpha$ I. carp Igs against Ig molecules from 6 different fish sera and mouse control serum was checked on immunoblotting analysis. As a result, R $\alpha$ I. carp Igs responded to Israeli carp, common carp, and tilapia Ig molecules. In flow cytometry study, however, R $\alpha$ I. carp Igs appeared to recognize 42.0%, 35.8% and <5% of Israeli carp, common carp and tilapia $Ig^+$ head kidney cells, respectively. The result suggests the heterogeneity between receptor Igs on B-like lymphocytes and soluble Igs in serum. It is crucial to obtain pure fish Igs to produce reagent antibodies as tools for the study on their specific immune responses.

• Clinical and Experimental Pediatrics
• /
• v.45 no.2
• /
• pp.183-191
• /
• 2002

Purpose : X-linked agammaglobulinemia(XLA) is an immunodeficiency caused by abnormalities in Bruton's tyrosine kinase(Btk), and is characterized by a deficiency of peripheral blood B cells. We studied the cytoplasmic expression of Btk protein and analyzed the Btk gene in peripheral blood mononuclear cells from two siblings and one cousin with XLA, as well as additional family members. Methods : Btk protein expression was analyzed by flow cytometry. Isolation of the coding sequence of the Btk gene was performed by amplification using the reverse transcription-polymerase chain reaction(RT-PCR) technique. Sequence alterations were screened by the single-stranded conformation polymorphism(SSCP) method and characterized by standard sequencing protocols. Results : Cytoplasmic expression of Btk protein in monocytes was not detected in three patients with XLA. In addition, Btk protein analysis clearly showed cellular mosaicism in monocytes from four obligate carriers, findings further supported by SSCP. A single base pair mutation(T to C) in Btk-exon three, which encodes the PH domain, was identified in four XLA patients. A diagnostic sequencing analysis was established to detect heterozygotic pattern in 4 carrier females. Furthermore, we found significant clinical heterogeneity in individuals with the same gene mutation. Conclusion : The implicating genetic alteration provided valuable clues to the pathogenesis of XLA in Korea and the flow cytometric analysis was suggested as a useful tool for rapid detection of XLA patients and carriers. The present study has identified a genetic mutation in the Btk coding region and demonstrated heterogeneity in clinical manifestations among patients with the same mutation. A flow cytometric analysis was found to be informative in establishing a deficiency of Btk protein in both patients and carriers and is recommended as a frontline procedure in the molecular diagnosis and work-up of XLA.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.31 no.6D
• /
• pp.779-784
• /
• 2011

Freeway FFS (Free-Flow Speed) under the state of LOS (Level of Service) A has been regarded as a homogeneous state to all levels of traffic volume. The features of low-density FFS is served as the basic data for a decision on limited maximal speed, accident analysis, simulation modeling etc. A few researches for the macroscopic characteristics of design and operation speed have been reported, and any study for the microscopic features of freeway free-flow speed under the state of low density has not been done. Therefore, the characteristics of low-density FFS according to the level of traffic volume (1-3 veh/30 sec) and daily hour periods (0-5, 6-8, 9-11, 12-19, 20-23) is microscopically analyzed in this study with huge volume and speed data. It was found that speed distributions are changed and show different behaviors under the conditions of traffic volume levels and daily time periods. V85s (85th percentile speed) at early morning and night periods decrease when levels of traffic volume increase, whereas V85s at day time do not show considerable differences. Especially, FFSs of levels of traffic volume at early morning and night periods, despite low density, is analyzed as heterogeneity, but homogeneity at day time.

• Journal of Korean Society of Environmental Engineers
• /
• v.31 no.4
• /
• pp.300-307
• /
• 2009

The transport of landfill leachate in the subsurface formations of unlined landfill sites is considered. The impacts of hydrogeological and chemical heterogeneities on the leachate transport are assessed by examining the results from a series of Monte-Carlo simulations. The landfill system simulated in this study is hypothetically represented with three levels of spatial variability for the hydrogeological and chemical parameter; (1) homogeneous hydraulic conductivity (K) and distribution coefficient ($K_d$), (2) K heterogeneity only, and (3) combined heterogeneities of K and $K_d$. To calculate the transport of leachate through negatively-correlated random hypothetical K-$K_d$ fields generated using geostatistical input parameters, a saturated flow model is linked with a contaminant transport model. Point statistic values such as mean, standard deviation, and coefficient of variation of the concentration were obtained from 100 Monte-Carlo trials. Results of point statistics show that the heterogeneities of K and $K_d$ in the landfill site prove to be an important parameter in controlling leachate concentrations. Consideration of combined K and $K_d$ heterogeneities results in enhancing the variability of contaminant transport. The variability in the leachate concentration for different realizations also increases as the distance between source and monitoring well increase.

• Ecology and Resilient Infrastructure
• /
• v.7 no.1
• /
• pp.1-14
• /
• 2020

In fluvial and riparian ecosystems, biogeomorphological research has considered the complex, multi-way relationships between biological and hydro-geomorphological components over a wide range of spatial and temporal scales. In this review, we discussed the scope and processes of fluvial biogeomorphology by explaining (1) the multi-lateral interactions between organisms and hydrogeomorphic conditions, (2) the relationships between biodiversity and habitat heterogeneity, and (3) the effects of disturbance on ecosystem patterns. Over time, an organism-landform complex along streams transitions in the sequences of geomorphic, pioneer, biogeomorphic, and ecological stages. Over space, water flow and sediment distributions interact with vegetation to modify channel topography. It is the habitat heterogeneity in streams that enhances riparian biodiversity. However, in the areas downstream of a dam, habitat types and conditions are substantially damaged and biodiversity should be reduced. In South Korea, riparian vegetation flourishes in general and, in particular, invasive species actively colonize in accordance with the changes in the fluvial conditions driven by local disturbances and global climate change. Therefore, the importance of understanding reciprocal relationships between living organisms and hydrogeomorphic conditions will ever increase in this era of rapid climate change and anthropogenic pressure. The fluvial biogeomorphic framework reviewed in this article will contribute to the ecological management and restoration of streams in Korea.

• Journal of Soil and Groundwater Environment
• /
• v.11 no.5
• /
• pp.9-19
• /
• 2006

The accurate estimation of groundwater recharge is important for the proper management of groundwater systems. The widely used techniques of groundwater recharge estimation include water table fluctuation method, baseflow separation method, and annual water balance method. However, these methods can not represent the temporal-spatial variability of recharge resulting from climatic condition, land use, soil storage and hydrogeological heterogeneity because the methods are all based on the lumped concept and local scale problems. Therefore, the objective of this paper is to present an effective method for estimating groundwater recharge with spatial-temporal variability using the SWAT model which can represent the heterogeneity of the watershed. The SWAT model can simulate daily surface runoff, evapotranspiration, soil storage, recharge, and groundwater flow within the watershed. The model was applied to the Musimcheon watershed located in the upstream of Mihocheon watershed. Hydrological components were determined during the period from 2001 to 2004, and the validity of the results was tested by comparing the estimated runoff with the observed runoff at the outlet of the catchment. The results of temporal and spatial variations of groundwater recharge were presented here. This study suggests that variations in recharge can be significantly affected by subbasin slope as well as land use.