• 제목/요약/키워드: flexible joints

검색결과 123건 처리시간 0.036초

Comparative Proteomic Analyses of Synovial Fluids and Serums from Rheumatoid Arthritis Patients

  • Noh, Ran;Park, Sung Goo;Ju, Ji Hyeon;Chi, Seung-Wook;Kim, Sunhong;Lee, Chong-Kil;Kim, Jeong-Hoon;Park, Byoung Chul
    • Journal of Microbiology and Biotechnology
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    • 제24권1호
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    • pp.119-126
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    • 2014
  • Rheumatoid arthritis (RA) is a chronic and systemic inflammatory disorder that primarily affects the flexible joints and may also affect a number of tissues and organs. The progression of RA involves an inflammatory response of the capsule around the joint, swelling of synovial cells with excess synovial fluid (SF), and the development of fibrous tissue in the synovium. Since the progressive pathology of the disease often leads to the irreversible destruction of articular cartilage and ankylosis of the joint, early diagnosis of RA is essential. Thus, we undertook a comparative proteomic approach to investigate novel biomarkers for early diagnosis using SFs and serums from RA patients. As a result, we identified 32 differentially expressed spots in SFs and 34 spots in serums. The differential expression of the STEAP4 and ZNF 658 proteins were validated using immunoblotting of the SFs and serums, respectively. These data suggest that differentially expressed proteins in SFs and serums could be used as RA-specific biomarkers for the diagnosis and monitoring of RA. Furthermore, these findings advance our understanding of the molecular etiopathogenesis of RA.

라이트의 유소니언 오토매틱 주택 시스템에 나타난 재료 및 공법에 관한 연구 (Materials and Methods in Usonian Automatic House System of Frank Lloyd Wright)

  • 김태영
    • 한국농촌건축학회논문집
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    • 제18권4호
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    • pp.1-8
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    • 2016
  • This study is to investigate the meaning and value of Usonian Automatic House System(UAHS) of Frank Lloyd Wright in his later period, focused on materials, methods, and his thoughts. The results of this study are follows. UAHS was the outcome of moderate cost and prefab house which Wright had successively attempted after the early Prairie period. The construction was simple and comparatively cheap, but subsequent automatics were difficult and expensive to build. Nevertheless, it was sufficiently flexible to support a rather wide range of house designs. Concrete was the inert mass and a plastic material. Wright saw a kind of weaving coming out of it. He also saw a kind of concrete masonry, steel for warp and masonry units for woof in the automatic concrete block. The reinforced bars in hollowed joints of concrete block increased the safety factor and affected the expression of the construction through the stabilization they provided. But they did not give concrete block the capability of structural span. Standardization as the soul of the machine might be seen in UAHS. The concrete blocks were more cheap, lighter, and larger hollowed plain than textile blocks in 1920s. But the variety of pattern and different block types in the UAHS were achieved at some sacrifice of standardization. The repetitive nature of production was compromised for artistic goals. The sense of compromise was not maximized, however, because the units as installed looked far more repetitive than they actually were.

한복 전시를 위한 마네킹에 관한 연구 (A Study on the Mannequins for the Display of Hanbok)

  • 김여경;김정민;홍나영
    • 복식
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    • 제63권6호
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    • pp.113-126
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    • 2013
  • The purpose of this study is to analyze the current use of mannequins that are designed to display Hanbok and put forward suggestions for improvement. In order to carry out the study, an analysis on the mannequins that are currently in the market was conducted along with a survey with professionals who are in charge of the display. The significance of the study is that it has gathered the opinions of professionals who are currently participating in the displays of Hanbok to lay the foundation for improvements. As Hanbok is a flat-pattern costume unlike the Western ones, the most prominent way to display is to lay them on the floor or hang them on the wall. Nevertheless, the mannequin displays are needed to show the beauty of Hanbok as the silhouette can only be completed when it is put on a body. A new type of mannequins that can portray the distinctive features of Korean beauty more effectively need to be developed. Although the museum and enterprise slightly differ in their preferences and requirements for the mannequins, both agree on the following criteria; the shape should be adjusted: the protruding breasts of the mannequin are not suitable for Hanbok, the body should be disassembled: all parts of the body should be separable and it should be flexible at the joints so that it can produce various poses, the face should represent the "koreaness" and the material should be soft. Based on these findings, we put forth the suggestion that a more suitable mannequin should be developed to portray the beauty of Hanbok.

파쇄대가 터널 주변 암반의 변형 거동에 미치는 영향에 대한 수치해석적 연구 (Numerical Analysis on the Effect of Fractured Zone on the Displacement Behavior of Tunnel)

  • 김창용;김광염;문현구;이승도;백승한
    • 터널과지하공간
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    • 제16권3호
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    • pp.218-231
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    • 2006
  • 이방성/비균질 암반은 터널 굴착에 의해 매우 다양한 변형거동을 나타내며, 이는 암반 내 존재하는 단층 및 절리 그리고 파쇄대 등과 같은 지질학적 요소들의 공간적인 특성에 의해 크게 좌우된다. 본 논문에서는 파쇄대가 존재할 경우 2차원 수치해석을 통해 여러 가지 영향인자들에 대한 매개변수 분석을 수행하였다. 그 결과 파쇄대 폭 및 위치 그리고 지보 등에 따라 터널 변위는 분석 위치마다 매우 상이하게 나타났다. 그러나 불연속면 및 파쇄대는 3차원적 기하구조를 나타내므로 3차원 지반 구조적 특성을 고려할 수 있는 3차원 해석이 필수적이라고 판단된다. 또한 기술적으로 안전하고 경제적인 터널 건설을 위하여 불확실한 지반조건 및 환경여건에 매우 유연하게 대처할 수 있는 설계/시공 기술이 필요하다고 판단된다.

패션쇼를 위한 3D 프린팅 의상 디자인 개발 연구 (A Study on the Development of 3D printed garments for Fashion Show)

  • 이현승
    • 한국의류산업학회지
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    • 제21권3호
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    • pp.267-276
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    • 2019
  • This study develops 3D-printed-garment collections for a fashion show presentation. A design concept using traditional patterns that consisted of garments regarding the limitation of the printing technology was investigated in order to develop the collection. The structures of the connecting joints of the textile parts which could be easily and sturdily interconnected were invented. Wearability as garments that could be naturally worn on the human body were sought. As a result, four 3D-printed-garments were developed. The 1st garment composed of objects based on a 'Yeon-Dang-Cho'-pattern was constructed as a geometric robe style using a FDM 3D printer and transparent TPU filaments. The 2nd and 3rd 3D-printed-garments composed of an object based on a 'Boe-Sang-Hwa'-pattern was constructed as a distorted one-piece exaggerating the silhouettes of shoulders and waist parts as well as a straight asymmetric tunic style that used the same printer and material as the 1st garment. The last garment composed of an object based on a 'Boe-Sang-Hwa'-pattern printed using a SLA 3D printer and flexible-liquid-resin was constructed attaching the objects on the fabric material by the hot-press machine. The four developed garments were presented in the opening fashion show of 'the 6th International 3D-printing Korea Expo'. This study provides a basic case for related studies to adapt 3D-printing technology in textile pattern development of garment construction.

변형경화형 시멘트 복합체를 사용한 프리캐스트 끼움벽의 내진성능 (Seismic Performance of Precast Infill Walls with Strain-Hardening Cementitious Composites)

  • 김선우;윤현도;장광수;윤여진
    • 콘크리트학회논문집
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    • 제21권3호
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    • pp.327-335
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    • 2009
  • 지진이 빈번하게 발생하는 지역에서는 비내진상세구조물은 지진 발생시 연약층을 형성하고 취성적 붕괴를 일으키게 된다. 그러나, 기존 구조물을 해체하고 내진상세 구조물을 신축하는 방법은 건설폐기물, 환경오염 및 민원 등 여러가지 문제들을 가지는 등 비경제적 방법이라 할 수 있다. 따라서 기존 구조물이 내진성능을 만족하도록 내진보강에 관한 많은 연구가 이루어졌으며, 이러한 내진보강방법에는 끼움벽, 철골브레이스, 연속벽, 부벽, 날개벽, 기둥/보의 자켓팅 등이 있다. 이 중 끼움벽 골조는 큰 변형과 접합부에서의 회전이 발생하는 골조와, 비교적 작은 변형에서도 전단파괴를 야기하는 끼움전단벽 등 복합적인 거동특성을 나타낸다. 따라서, 이러한 시스템의 거동특성은 개개의 골조나 벽에서 나타나는 거동특성과 매우 다르게 된다. 본 연구에서는 끼움벽의 내진성능을 평가하고자 하였으며, 손상에너지의 효과적 흡수를 위해 변형경화형 시멘트 복합체 (SHCC)를 사용하였다. 실험은 1/3 축소모형의 끼움벽을 반복가력하는 것으로 계획하였다. 실험 결과, SHCC 끼움벽에서는 섬유의 가교작용을 통해 시멘트 복합체 내 응력을 재분배함으로써 미세균열이 발생하였으며, 강도 및 에너지소산능력이 우수한 것으로 나타났다.

A Study on Development of Off-Line Path Programming for Footwear Buffing Robot

  • Lho, Tae-Jung;Kang, Dong-Joon;Che, Woo-Seung;Kim, Jung-Young;Kim, Min-Sung
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2004년도 ICCAS
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    • pp.1469-1473
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    • 2004
  • We suggest how to program off-line robot path along shoes' outsole shape in the footwear buffing process by a 5-axis microscribe system like robot arms. This microscribe system developed consists a 5-axis robot link with a turn table, signal processing circuit, PC and an application software program. It makes a robot path on the shoe's upper through the movement of a microscribe with many joints. To do this, first it reads 5-encoder's pulse values while a robot arm points a shoes' outsole shape from the initial status. This system developed calculates the encoder pulse values for the robot arm's rotation and transmits the angle pulse values to the PC through a circuit. Then, Denavit-Hartenberg's(D-H) direct kinematics is used to make the global coordinate from robot joint one. The determinant is obtained with kinematics equation and D-H variable representation. To drive the kinematics equation, we have to set up the standard coordinates first. The many links and the more complicated structure cause the difficult kinematics problem to solve in the geometrical way. Thus, we can solve the robot's kinematics problems efficiently and systematically by Denavit-Hartenberg's representation. Finally, with the coordinate values calculated above, it can draw a buffing gauge-line on the upper. Also, it can program off-line robot path on the shoes' upper. We are subjected to obtaining shoes' outline points, which are 2 outlines coupled with the points and the normal vector based on the points. These data is supposed to be transformed into .dxf file to be used for data of automatic buffing robot. This system developed is simulated by using spline curves coupled with each point from dxf file in Autocad. As a result of applying this system to the buffing robot in the flexible footwear manufacturing system, it can be used effectively to program the path of a real buffing robot.

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스쿼시 백핸드 드라이브 동작시 상지 분절의 운동학적 변인 분석 (The Kinematic Analysis of the Upper Extremity during Backhand Stroke in Squash)

  • 안용환;류지선;류호영;소재무;임영태
    • 한국운동역학회지
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    • 제17권2호
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    • pp.145-156
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    • 2007
  • The purposes of this study were to investigate kinematic parameters of racket head and upper extremities during squash back hand stroke and to provide quantitative data to the players. Five Korean elite male players were used as subjects in this study. To find out the swing motion of the players, the land-markers were attached to the segments of upper limb and 3-D motion analysis was performed. Orientation angles were also computed for angular movement of each segment. The results were as follows. 1) the average time of the back hand swing (downswing + follow-through) was 0.39s (0.24 s + 0.15 s). 2) for each event, the average racket velocity at impact was 11.17m/s and the velocity at the end of swing was 8.03m/s, which was the fastest swing speed after impact. Also, for each phase, 5.10m/s was found in down swing but 7.68m/s was found in follow-through. Racket swing speed was fastest after the impact but the swing speed was reduced in the follow-through phase. 3) in records of average of joints angle, shoulder angle was defined as the relative angle to the body. 1.04rad was found at end of back swing, 1.75rad at impact and it changes to 2.35 rad at the end of swing. Elbow angle was defined as the relative angle of forearm to upper arm. 1.73rad was found at top of backswing, 2.79rad at impact, and the angle was changed to 2.55rad at end of swing. Wrist angle was defined as the relative angle of hand to forearm. 2.48rad was found at top of backswing, 2.86rad at impact, and the angle changes to 1.96rad at end of swing. As a result, if the ball is to fly in the fastest speed, the body has to move in the order of trunk, shoulder, elbow and wrist (from proximal segment to distal segment). Thus, the flexibility of the wrist can be very important factor to increase ball speed as the last action of strong impact. In conclusion, the movement in order of the shoulder, elbow and the wrist decided the racket head speed and the standard deviations were increased as the motion was transferred from proximal to the distal segment due to the personal difference of swing arc. In particular, the use of wrist (snap) may change the output dramatically. Therefore, it was concluded that the flexible wrist movement in squash was very important factor to determine the direction and spin of the ball.

암반사면의 절리빈도 특성에 따른 프리스플리팅 발파공법의 적용성 연구 (A Study on Applicability of Pre-splitting Blasting Method According to Joint Frequency Characteristics in Rock Slope)

  • 김신;이승중;최성웅
    • 화약ㆍ발파
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    • 제28권2호
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    • pp.1-16
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    • 2010
  • 본 연구에서는 암반사면형성 작업시 최종벽면에 적용된 프리스플리팅(pre-splitting) 발파공법의 발파효과와 관련하여 발파 후 벽면의 암반손상이 장약된 폭약의 폭력 보다는 암반 내에 발달된 불연속면의 발달 형태에 따라 더 큰 영향을 보일 수 있음을 규명하였다. 이를 위하여 불연속면을 대표할 수 있는 절리에 대한 조사를 통해 발파 후 벽면 암반의 절리군 분포양상을 4가지 Case로 분류하고, 파쇄도 분석 영상처리시스템을 통해 벽면에 나타나는 암반블록의 크기 빈도를 비교 분석함으로써 벽면의 암반손상도를 파악하였다. 절리군이 1개 이하로 발달하는 경우, 분석된 블록의 크기 중 2,000mm 이상 되는 부분이 42%를 차지하여 프리스플리팅 발파공법의 효과를 뚜렷이 확인할 수 있었으며, 2~3개의 절리군이 일방향으로 발달하는 경우와 교차되면서 발달하는 경우, 블록의 크기는 1,000~2,000mm 사이에 각각 43.6% 및 35.8%의 빈도로 분포하는 것으로 나타나 프리스플리팅 발파공법에 의한 발파효율이 다소 떨어지는 양상을 보였다. 그러나 3개 이상의 절리군이 불규칙하게 발달하는 경우에는 블록의 크기가 250~500mm 사이에 35%의 빈도로 분포하고 1,000mm 이상의 크기에 대해서는 거의 나타나지 않는 양상을 보였다. 따라서 이러한 경우 프리스플리팅 발파공법에 의한 발파 효과는 거의 없이 일반적인 발파가 이루어졌다고 볼 수 있었다. 또한 PFC2D에 의한 발파수치해석결과, 암반 내부로의 손상영역 발생은 본 발파보다는 프리스플리팅 발파공법에 의해 직접적인 영향을 받을 수 있음을 확인하였으며, 따라서 향후 사면 형성을 위한 프리스플리팅 발파공법을 적용할 경우에는 사전 지표지질조사를 시행하여 절리를 비롯한 불연속면과 관련된 사항을 충분히 파악할 필요가 있으며, 시공진행에 따라 예상보다 많은 절리군이 나타날 경우에는 프리스플리팅 발파공법의 설계 조정이 필요할 것으로 판단된다.

버핑 로봇의 오프라인 경로 프로그래밍용 5축 마이크로스크라이브 개발 및 응용 (Development of 5-Axis Microscribe System for Off-Line Buffing Robot Path Programming and Its Application)

  • 노태정
    • 한국산학기술학회논문지
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    • 제9권1호
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    • pp.1-8
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    • 2008
  • 신발 버핑공정에서 로봇 메카니즘과 같은 5축 마이크로스크라이브에 의하여 신발창 형상을 따라서 버핑 로봇 경로를 오프라인으로 프로그래밍하는 방법을 제안한다. 개발한 마이크로스크라이브 시스템은 턴테이블이 부착된 5축 로봇링크, 신호처리장치, PC 및 응용 소프트웨어 프로그램으로 구성되어 있다. 많은 조인트를 가진 마이크로스크 라이브를 신발창 표면을 따라 이동시킴으로써 로봇 경로가 만들어진다. 개발시스템은 마이크로스크라이브 암의 회전에 해당되는 엔코더 펄스 값을 환산하며, 이 각도 값을 신호처리장치를 통하여 PC로 전송한다. Denavit-Hartenberg's(D-H) 직접 키네메틱스가 마이크로스크라이브 조인트 각도 값으로서 글로벌 좌표값을 만드는데 사용된다. 마이크로스크라이브의 키네메틱스 문제는 D-H 표현에 의하여 효과적이고 시스템적으로 해결된다. 개발시스템은 D-H식에 의하여 계산된 좌표 값으로서 신발 갑피 위에 버핑 게이지 라인을 그릴 수 있으며, 또한 신발 갑피 위에 각 점들과 그 점에 수직인 벡터와 결합된 2개의 외곽 라인으로서 로봇 경로를 얻는다. 개발시스템을 FMS의 버핑 로봇에 적용함으로써 실제적인 버핑 로봇의 경로를 프로그래밍하는데 효과적으로 사용될 수 있다.