• Title/Summary/Keyword: flemilineatins A-B

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Two New Flavanones from the Leaves of Flemingia lineata (L.) Aiton

  • Tanjung, Mulyadi;Tjahjandarie, Tjitjik Srie;Mardhiyyah, Shola;Rahman, Ghinsha Zakatina;Aldin, Muhammad Fajar;Saputri, Ratih Dewi;Ahmat, Norizan
    • Natural Product Sciences
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    • v.28 no.2
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    • pp.58-61
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    • 2022
  • Three isoprenylated flavanones were isolated from the leaves of Flemingia lineata (L.) Aiton. Among them are two new flavanones, flemilineatins A and B (1-2), along with 6-isoprenyl eridioctyol (3). Their structures were determined using HRESIMS data and NMR spectra. Flavanones 1 - 3 were assayed in the HeLa cancer cells. Compound 1 showed moderate activity with an IC50 value of 11.2 μM.

Two New Flavanones from the Leaves of Flemingia lineata (L.) Aiton

  • Tanjung, Mulyadi;Tjahjandarie, Tjitjik Srie;Mardhiyyah, Shola;Rahman, Ghinsha Zakatina;Aldin, Muhammad Fajar;Saputri, Ratih Dewi;Ahmat, Norizan
    • Natural Product Sciences
    • /
    • v.28 no.1
    • /
    • pp.40-43
    • /
    • 2022
  • Three isoprenylated flavanones were isolated from the leaves of Flemingia lineata (L.) Aiton. Among them are two new flavanones, flemilineatins A and B (1-2), along with 6-isoprenyl eridioctyol (3). Their structures were determined using HRESIMS data and NMR spectra. Flavanones 1-3 were assayed in the HeLa cancer cells. Compound 1 showed moderate activity with an IC50 value of 11.2 μM.