• Asian-Australasian Journal of Animal Sciences
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• 제30권11호
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• pp.1550-1556
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• 2017

Objective: This study estimated the genetic parameters for productive and reproductive traits. Methods: The data included production and reproduction records of animals that have calved between 1979 and 2013. The genetic parameters were estimated using multivariate mixed models (DMU) package, fitting univariate and multivariate mixed models with average information restricted maximum likelihood algorithm. Results: The estimates of heritability for milk production traits from the first three lactation records were $0.03{\pm}0.03$ for lactation length (LL), $0.17{\pm}0.04$ for lactation milk yield (LMY), and $0.15{\pm}0.04$ for 305 days milk yield (305-d MY). For reproductive traits the heritability estimates were, $0.09{\pm}0.03$ for days open (DO), $0.11{\pm}0.04$ for calving interval (CI), and $0.47{\pm}0.06$ for age at first calving (AFC). The repeatability estimates for production traits were $0.12{\pm}0.02$, for LL, $0.39{\pm}0.02$ for LMY, and $0.25{\pm}0.02$ for 305-d MY. For reproductive traits the estimates of repeatability were $0.19{\pm}0.02$ for DO, and to $0.23{\pm}0.02$ for CI. The phenotypic correlations between production and reproduction traits ranged from $0.08{\pm}0.04$ for LL and AFC to $0.42{\pm}0.02$ for LL and DO. The genetic correlation among production traits were generally high (>0.7) and between reproductive traits the estimates ranged from $0.06{\pm}0.13$ for AFC and DO to $0.99{\pm}0.01$ between CI and DO. Genetic correlations of productive traits with reproductive traits were ranged from -0.02 to 0.99. Conclusion: The high heritability estimates observed for AFC indicated that reasonable genetic improvement for this trait might be possible through selection. The $h^2$ and r estimates for reproductive traits were slightly different from single versus multi-trait analyses of reproductive traits with production traits. As single-trait method is biased due to selection on milk yield, a multi-trait evaluation of fertility with milk yield is recommended.

• 한국자기공명학회논문지
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• 제5권2호
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• pp.99-109
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• 2001

Authors investigated neuronal changes of local cellular metabolism in the cerebral lesions of Parkinsonian symptomatic side between before and after stereotactic neurosurgery by follow-up 1H magnetic resonance spectroscopy (MRS). Patients with Parkinson's disease (PD) (n = 15) and age-matched normal controls (n = 15) underwen MRS examinations using a stimulated echo acquisition mode (STEAM) pulse sequence that provided 2${\times}$2${\times}$2 ㎤ (8ml) volume of interest in the regions of substantia nigra, thalamus, and lentiform nucleus. Spectral parameters were 20 ms TE, 2000 ms TR, 128 averages,2500 Hz spectral width, and 2048 data points. Raw data were processed by the SAGE data analysis package (GE Medical Systems). Peak areas of N-acetylaspartate (NAA), creatine (Cr), choline-containing compounds (Cho), inositols (Ins), and the sum (Glx) of glutamate and GABA were calculated by means of fitting the spectrum to a summation of Lorentzian curves using Marquardt algorithm. After blindly processed, we evaluated neuronal alterations of observable metabolite ratios between before and after stereotactic neurosurgery using Pearson product-moment analysis (SPSS, Ver. 6.0). A significant reduction of NAA/Cho ratio was observed in the cerebral lesion in substantia nigra of PD patient related to the symptomatic side after neurosurgery (P : 0.03). In thalamus, NAA/Cho ratio was also significantly decreased in the cerebral lesion including the electrode-surgical region (P : 0.03). A significant reduction of NAA/Cho ratio in lentiform nucleus was not oberved, but tended toward significant reduction after neurosurgery (P = 0.08). In particular, remarkable lactate signal was noted from the surgical thalamic lesions of 6 among 8 patients and internal segments of globus pallidus of 6 among 7 patients, respectively. Significant metabolic alterations of NAA/Cho ratio might reflect functional changes of neuropathological processes in the lesion of substantia nigra, thalamus, and lentiform nucleus, and could be a valuable finding fur evaluation of Parkinson's disease after neurosurgery. Increase of lactate signals, being remarkable in surgical lesions, could be consistent with a common consequence of neurosurgical necrosis. Thus, IH MRS could be a useful modality to evaluate the diagnostic and prognostic implications fur Parkinsons disease after functional neurosurgery.

• 한국진공학회지
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• 제16권4호
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• pp.244-249
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• 2007

분동식압력계는 정밀한 압력 측정의 기준 장비로 널리 사용되고 있다. 그것은 분동압력계가 견고하고 정확하며 이동이 간편하고 압력의 정의를 물리적으로 구현할 수 있기 때문이다. 기본적으로 분동식압력계는 분동과 피스톤/실린더 장치로 구성되며 실린더 안에 직경이 꼭 맞는 피스톤이 수직으로 삽입된 구조를 갖고 있다. 측정하려는 압력은 피스톤 아래에 작용하여 윗방향 힘을 발생시키고 피스톤 위에 얹혀 있는 분동에 의해 발생하는 아랫방향 힘과 평형을 이루게 된다. 이때 피스톤 자체의 하중은 항상 작용하므로 분동식압력계는 보통 10 kPa이상의 압력 범위에서 주로 사용된다. 기존의 방식은 피스톤 아래의 높은 압력을 기준으로 사용하지만 본 방식은 피스톤 주위의 낮은 압력을 기준압력으로 사용하여 보다 더 낮은 압력의 측정이 가능하다. 본 논문에서는 이를 효율적으로 구현한 새로운 장치를 소개하고 실제로 1.33 kPa, 13.3 kPa 두 측정범위를 갖는 정밀한 저진공 게이지(MKS, CDG)를 교정, 평가한 결과에 대해서 기술하였다.

• 대한지역사회영양학회지
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• 제13권1호
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• pp.34-45
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• 2008

For the correct dietary habit and balanced dietary intake of aged people, the nutrition management that fits to the dietary behavior change stage has to be accomplished. In order to do so, in this paper, we chose 175 women that are aged more than 65 years old who are rural long life community residents and surveyed the dietary intake for 2 days including a twice depth interview and the 24 hour recall method. Also, for the sake of our aim, using the transtheoretical model, the dietary behavior change stage group was divided into the contemplation stage group, the preparation stage group, the action stage group and the maintenance stage group. The results are as follows: In the intake amount of protein (p < 0.01), vitamin $B_1$ (p < 0.05) and vitamin $B_6$ (p < 0.05), the intake amount of these nutrients in the action stage group and the maintenance stage group were significantly larger than the intake amount in the contemplation stage group and the preparation stage group. The nutrition evaluation according to the dietary behavior change stage, the ratio of subjects who took insufficient amount of energy, protein, vitamin A, and vitamin C were low as the dietary behavior change stage was upgraded. The subjects of maintenance stage group were most likely to consume vegetables more than once a day, and consume fruits and milk and milk products more than 5 times/week. MAR [13], MAR [10] and MAR [4] of subjects in the action stage group and the maintenance stage group were significantly higher than MAR [13], MAR [10] and MAR [4] of subjects in the contemplation stage group and the preparation stage group (p < 0.001). From the above results, there were differences of nutrient intakes according to the dietary behavior change stage. Therefore, it is considered that the intervention for the dietary behavior motivation induction has to be advanced before accomplishing the individually fitting intervention at the time of nutrient management intervention.

• Journal of Animal Science and Technology
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• 제50권2호
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• pp.151-156
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• 2008

본 연구는 임의회귀모형을 이용하여 한우 거세우 체중에 대해서 유전모수 추정을 하고 이것을 단형질 개체모형의 결과와 비교해 보고자 실시하였다. 분석에 이용한 자료는 총 1,372두의 한우 거세우의 체중 자료로, 농협중앙회 가축개량사업소에서 실시한 한우 후대검정우의 기록이다. 이차의 임의회귀 모형에 적용한 결과 유전력이 총 800일령까지의 검정기간에 대해 0.17~0.30의 범위로 나타났다. 개체모형을 통해 얻은 유전력은 0.24~0.36의 범위로 나타났다. 측정일간의 영구환경효과의 상관은 검정일령이 늘어남에 따라 함께 증가하는 경향을 보였다. 반면, 측정일간의 유전상관의 경우 검정초기에는 0.30 정도의 약한 음의 상관을 보이지만, 검정이 이뤄짐에 따라 상관이 점차 증가하여 검정이 종료될 무렵이면 거의 고정되는 것으로 나타났다. 임의회귀모형과 개체모형의 결과를 비교해보면 두가지 모형 모두 비슷한 경향을 보여 큰 차이를 보이지 않았다. 따라서, 임의회귀모형을 한우에 대한 국가유전능력평가에 사용하는 것이 가능할 것으로 사료된다.

• 대한치과보철학회지
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• 제44권4호
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• pp.421-431
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• 2006

Statement of problem : Accurate impression is essential to success of implant prostheses. But there have been few studies about the accuracy of fixture-level impression technique in internal connection implant system. Purpose: This study evaluated the accuracy of splinted fixture-level impression technique using clinical methods and the effect of internal hex on fit of superstructure in internal connection implant system (Astra Tech). Material and method : Two metal master frameworks made from two abutments (Cast-to Abutment ST) each for parallel and divergent conditions and a corresponding. passively fitting, dental stone master cast with four future replicas (Fixture Replica ST) were fabricated. Ten dental stone casts were made with vinyl polysiloxane impressions from the master cast by acrylic resin splinted fixture-level impression technique. To evaluate the accuracy of impression technique, the fit of master frameworks for test models was evaluated using screw resistance test (SRT) and one-screw test. The results of SRT were recorded as SRT values from grade 1 to grade 5 by 1/4 turn. And to evaluate the effect of hex on fit of superstructure, the same tests were performed after removing hexes of master frameworks. Results: 1. There was only one case (2.5%) showing SRT value of test model below ade 2 in total before and after removing hexes of master frameworks. And, by removing hexes. SRT values decreased in only one test model (5%) and did not change in 17 test models (85%). 2. SRT values of the 1$^{st}$ screws were grade 2 in 80% of cases before, and grade 1 in 80% of cases after removing hexes. And, by removing hexes, SRT values decreased in 72.5% of cases. 3. SRT values of the 2$^{nd}$ screws were grade 3 in 85% of cases before, and grade 3 in 95% of cases after removing hexes. And, by removing hexes, SRT values did not change in 85% of cases. 4. There were only 2 cases regarded as acceptable fit by one-screw test, and SRT values of 2$^{nd}$ screws of both cases were grade 2. Conclusion. Within the limitations of this study, future-level impression of internal connection implant system is considered to obtain inaccurate working cast, even using acrylic resin splinted impression technique. And, it is considered to be unable improve the fit to remove the hexes of implant restoration.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제34권6호
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• pp.398-403
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• 2012

Purpose: Mandible resection and discontinuity defect created lead to aesthetic and functional problems. The iliac crest bone graft exhibits relative ease for bone harvesting, possibility of two team approach, ability to close the wound primarily, large amount of corticocancellous bone and relatively few complications. Whereas the use of free vascularized flaps has donor site morbidity and worse-fitting bone contour, the use of nonvascularized iliac bone graft has advantages in the operation time and patients' recovery time. So, nonvascularized iliac bone graft could be an attractive option. Methods: Twenty-one patients (M:F=1:1.1) underwent iliac crest bone harvesting for reconstruction of mandibular discontinuity defect (mean length : $61.6{\pm}17.8$ mm), from May 2005 to October 2011 at the Department of Oral and Maxillofacial Surgery in Kyungpook National University. The average age was $44.1{\pm}16.4$ years and the mean follow up periods was $28.2{\pm}22.7$ months. Bone resorption rate, according to age, sex, primary lesion, location and distance of defect, type of fixation plate, time of graft and pre-operative radiation therapy, were measured in each patient. Results: The mean bone resorption rate was $16.1{\pm}9.0%$. Bone resorption rate was significantly increased in mandibular defect that is over 6 cm in size (P=0.015, P<0.05) and the cases treated pre-operative radiation therapy (P=0.017, P<0.05). All was successfully fixed and maintained for the long-term follow-up. There were a few donor site complications and almost all patients were shown favorable outcome without severe bone resorption in this study. Conclusion: The nonvascularized iliac bone graft seems to be a reasonably reliable treatment option for reconstruction of mandibular discontinuity defects.

• 한국의학물리학회지:의학물리
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• 제23권4호
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• pp.234-238
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• 2012

눈꺼풀에 발생한 종양의 치료를 위해서는 종종 고에너지 전자선이 이용되며, 이 경우 환자의 시력 보호를 위해 금속차폐체를 눈꺼풀과 안구 사이에 삽입하고 방사선 치료를 시행한다. 차폐체에 접한 눈꺼풀 안쪽의 방사선량 확인을 위해서는 매우 작은 측정도구가 필요하며, 굽은 경계면의 특성상 유연한 측정도구가 바람직한데, radiochromic 필름 도시메트리는 이 목적에 매우 적합하다. 작으면서도 휘어진 경계면을 따라서 선량을 측정하기 위해, 눈꺼풀 팬텀과 차폐체 사이에 3-mm 폭의 EBT2 필름 띠를 삽입하고, 6MeV의 전자선을 조사 후, 선량분포를 얻었다. 금속차폐체와 동일한 크기로 아크릴 재질의 차폐체를 제작하여, 금속인공영상물이 없는 CT 영상을 얻은 후, 이를 이용하여 몬테칼로 전산모사를 수행하였다. 전산모사에서는 실제 안구차폐체의 재질을 따라 텅스텐, 알루미늄 및 스테인레스 스틸 등의 물질 정보를 이용하였다. 이렇게 얻은 전산모사 결과는 필름 측정과 2.1% 내에서 일치하였다. 밀리미터 크기 정도로 작고 또한 휘어진 영역에서 radiochromic 필름 도시메트리는 취급도 용이할 뿐만 아니라 만족스런 정확도를 보여주고 있다.

• 물과 미래
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• 제14권4호
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• pp.35-52
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• 1981

본 연구는 전국 주요 지점에 대한 월별, 계절별 및 연우량을 기본자료집단으로 하여 지점 및 지역 빈도 해석을 실시함으로써 면적 강우량을 산정한 내용이다. 기본자료집단은 전반기(1916년∼1944년; 29년간)와 후반기(1960년∼1979년; 20년간)로 양분하여 처리하고 비교 검토하였다. 지점 빈도해석에 있어서 적정 분포형은 변수변환법을 적용하고, $$-test 법을 이용하여 정규성 검정으로 설정하였으며, 지역 빈도 해석은 지형인자와 수문기상학적 인자를 고려하여 전국을 5개권역으로 구분하고 Thiessen 방법과 등우선법(Isohyetal Method)을 적용하여 비교 검토하였다. 본 연구를 통하여 얻어진 성과는 아래와 같다. 1) 전반기 자료집단에 의한 전국의 면적 강우량치는 후반기 자료집단에 의한 해석 결과치보다 70∼80mm 작은 값을 나타내고 있으므로 보아 현재까지의 1,150mm를 1,180mm 정도를 상향조정함이 바람직하다고 생각한다. 2) 전국을 5개 권역으로 구분하여 연평균 면적 강우량을 산정한 바, 춘계의 면적 강수량이 타계절에 비하여(약 5신) 크게 증가하고 있음은 수자원 적기 확보 방안 수립에 특기할 점이라 하겠다. 3) 면적 강수량 해석은 권역별로 구분하여 등우선도법으로 해석함이 합리적 방법이라고 생각된다.

• 한국측량학회지
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• 제27권6호
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• pp.699-710
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• 2009

한 국가에서 지오이드모델은 그 나라의 일관된 표고기준면을 제공함으로써 정확한 정표고를 결정할 수 있게 하며, 국가기준점의 평면위치 결정시 지오이드고를 고려한 측지망 조정계산을 실시함으로써 좌표결정의 정확도를 높일 수 있다. 본 연구는 말레이시아나 인도네시아와 비슷한 조건의 동남아시아 국가인 필리핀이 자국의 지오이드모델을 어떻게 개발하는 것이 최선인지 그 방법론을 연구한 연구이다. 따라서 본 연구에서는 전반적인 지오이드 결정이론을 살펴보고, 아시아 국가들에서의 지오이드 개발사례를 통하여 필리핀 일원에 가장 적합한 지오이드 모델 개발방안을 제시하고자 하였으며, 필리핀 일원에서 최신의 지구중력장 모델인 EGM2008을 해석하여 지오이드고와 중력이상을 계산하였다. 연구결과 항공중력방법에 기반한 중력 지오이드모델을 개발하고, 200점 내외의 GPS/leveling데이터에 의한 기하학적 지오이드고를 합성하여 하이브리드 지오이드 모델을 개발하는 것이 가장 합리적인 방법으로 연구되었다. 또한 스토크스적분의 수행은 4밴드 구면 FFT방법이, 중력지오이드모델 개발에는 EGM2008과 SRTM에 의한 remove and restore 기법이, 하이브리드 지오이드모델의 개발에는 Least square collocation 알고리즘이 제안되었다.