• Title/Summary/Keyword: fission

Search Result 676, Processing Time 0.032 seconds

The Change of Mitochondrial Fusion and Fission in human Skeletal Muscle with Aging

  • Cho, Hyung-Jun;Park, Soo-Yeon
    • Biomedical Science Letters
    • /
    • v.18 no.2
    • /
    • pp.112-122
    • /
    • 2012
  • A gradual change of molecules that are related in fission and fusion is occurred during aging process. Although aging effects on mitochondrial fusion and fission are investigated, it is still unclear that the extent of the change in mitochondria fusion and fission periodically. In this study we investigated the changes of mitochondrial proteins involved in fusion (Mfn2, Opa1) and fission (Drp1, Fis1) in the human gracilis muscle ranging from 10 to 50 years of age (n=40). The gracilis muscle showed a significant increase in muscle apoptotic changes in the age of 50s compared with 10s by using in situ terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL). The expression levels of Drp1 and Fis1 (P<0.01, P<0.05) mRNA were significantly elevated and the Mfn2 and Opa1 (P<0.01, P<0.05) levels were decreased from older individuals. The ratio of fission and fusion was altered and the level of increment of fission gene was greater than fusion gene decrement in the age of 50s. These findings suggest that changes of mitochondrial fusion and fission proteins related with aging might contribute to aged muscle apoptosis.

Acceleration method of fission source convergence based on RMC code

  • Pan, Qingquan;Wang, Kan
    • Nuclear Engineering and Technology
    • /
    • v.52 no.7
    • /
    • pp.1347-1354
    • /
    • 2020
  • To improve the efficiency of MC criticality calculation, an acceleration method of fission source convergence which gives an improved initial fission source is proposed. In this method, the MC global homogenization is carried out to obtain the macroscopic cross section of each material mesh, and then the nonlinear iterative solution of the SP3 equations is used to determine the fission source distribution. The calculated fission source is very close to the real fission source, which describes its space and energy distribution. This method is an automatic computation process and is tested by the C5G7 benchmark, the results show that this acceleration method is helpful to reduce the inactive cycles and overall running time.

A Study on Amplification and Deformation of Long-Period Waves (해양장파의 증폭과 변형에 대한 연구)

  • Bae, Jae-Seok;Shin, Choong-Hun;Cho, Young-Joon;Yoon, Sung-Bum
    • Proceedings of the Korea Water Resources Association Conference
    • /
    • 2011.05a
    • /
    • pp.45-49
    • /
    • 2011
  • 본 연구에서는 일본 전력중앙연구소에서 수행된 wave fission 수리모형실험 자료를 토대로 일차원 FUNWAVE 수치모형을 이용하여 wave fission 현상을 재현하는 수치모의를 수행하였다. FUNWAVE 수치모형은 Boussinesq 방정식을 지배방정식으로 사용하고 있으며 파의 분산효과와 비선형 효과를 고려할 수 있는 수치모형이다. 따라서 wave fission의 주된 발생원인인 분산효과와 비선형효과에 대한 고려를 통해 수치모의 결과는 수리모형실험의 관측치와 상당히 잘 일치함을 확인할 수 있었다. 또한, 본 연구에서는 추가적으로 해수의 흐름이 존재하는 경우를 가정하고 수로 내 일정한 유량의 흐름을 추가하여 wave fission 일차원 수치모의를 수행하였다. 수치모의 결과 파의 진행방향과 반대방향으로 흐름이 존재하는 경우 wave fission으로 인한 수면변위의 크기가 상대적으로 증가함을 확인할 수 있었으며 반대로 파의 진행방향과 동일한 방향으로 흐름이 존재하는 경우 wave fission으로 인한 수면변위의 크기가 상대적으로 감소함을 확인할 수 있었다.

  • PDF

Numerical studies on the important fission products for estimating the source term during a severe accident

  • Lee, Yoonhee;Cho, Yong Jin;Lim, Kukhee
    • Nuclear Engineering and Technology
    • /
    • v.54 no.7
    • /
    • pp.2690-2701
    • /
    • 2022
  • In this paper, we select important fission products for the estimation of the source term during a severe accident of a PWR. The selection is based on the numerical results obtained from depletion calculations for the typical PWR fuel via the in-house code named DEGETION (Depletion, Generation, and Transmutation of Isotopes on Nuclear Application), release fractions of the fission products derived from NUREG-1465, and effective dose conversion coefficients from ICRP 119. Then, for the selected fission products, we obtain the adjoint solutions of the Bateman equations for radioactive decay in order to determine the importance of precursors producing the aforementioned fission products via radioactive decay, which would provide insights into the assumption used in MACCS 2 for a level 3 PSA analysis in which up to six precursors are considered in the calculations of radioactive decays for the fission product after release from the reactor.

Effects of Gap Resistance and Failure Location on prompt Fission Gas Release from a Cladding Breach

  • Tak, Nam-Il;Chun, Moon-Hyun;Ahn, Hee-Jin;Park, Jong-Kil;Rhee, In-Hyoung
    • Proceedings of the Korean Nuclear Society Conference
    • /
    • 1997.05a
    • /
    • pp.184-189
    • /
    • 1997
  • A prompt fission gas release model incorporating the resistance to gas flow in the gap was developed and the effects of gap resistance and failure location on prompt fission gas release from the cladding breach were assessed. The process of prompt fission gas release from the plenum and gap into the coolant was modeled in accordance with three major phenomena: (1) transient gas flow in the gap, (2) the growth of the fission gas bubble while it is still attached to the breach, and (3) the detachment of the fission gas bubble from the breach and mixing with the coolant. The cumulative mass release fraction by the present model was calculated for the case of Young-Gwang 3 & 4 nuclear fuel rod as a typical example. The results showed that the release behavior of prompt fission gas with time was different from the frictionless model which has frequently been used in a simplified approach, and that the location of cladding failure was another key factor for the prompt fission gas release process due to the resistance in the gap.

  • PDF

A CLASSIFICATION OF UNIQUELY DIFFERENT TYPES OF NUCLEAR FISSION GAS BEHAVIOR

  • HOFMAN GERARD L.;KIM YEON SOO
    • Nuclear Engineering and Technology
    • /
    • v.37 no.4
    • /
    • pp.299-308
    • /
    • 2005
  • The behavior of fission gas in all major types of nuclear fuel has been reviewed with an emphasis on more recently discovered aspects. It is proposed that the behavior of fission gas can be classified in a number of characteristic types that occur at a high or low operating temperature, and/or at high or low fissile burnup. The crystal structure and microstructure of the various fuels are the determinant factors in the proposed classification scheme. Three types of behavior, characterized by anisotropic $\alpha$-U, high temperature metallic $\gamma$-U, and cubic ceramics, are well-known and have been extensively studied in the literature. Less widely known are two equally typical low temperature kinds: one associated with fission induced grain refinement and the other with fission induced amorphization. Grain refinement is seen in crystalline fuel irradiated to high burnup at low temperatures, whereas breakaway swelling is observed in amorphous fuel containing sufficient excess free-volume. Amorphous fuel, however, shows stable swelling if insufficient excess free-volume is available during irradiation.

The coordinated regulation of mitochondrial structure and function by Drp1 for mitochondrial quality surveillance

  • Cho, Hyo Min;Sun, Woong
    • BMB Reports
    • /
    • v.52 no.2
    • /
    • pp.109-110
    • /
    • 2019
  • Mitochondrial morphology is known to be continuously changing via fusion and fission, but it is unclear what the biological importance of this energy-consuming process is and how it develops. Several data have suggested that mitochondrial fission executed by Drp1 is necessary to select out a damaged spot from the interconnected mitochondrial network, but the precise mechanism for the recognition and isolation of a damaged sub-mitochondrial region during mitochondrial fission is yet unclear. Recently, Cho et al. found that the mitochondrial membrane potential (MMP) is transiently reduced by the physical interaction of Drp1 and mitochondrial Zinc transporter, Zip1, at the fission site prior to the typical mitochondrial division, and we found that this event is essential for a mitochondrial quality surveillance. In this review, Cho et al. discuss the role of a mitochondrial fission in the mitochondrial quality surveillance system.

Development of a Fission Product Transport Module Predicting the Behavior of Radiological Materials during Severe Accidents in a Nuclear Power Plant

  • Kang, Hyung Seok;Rhee, Bo Wook;Kim, Dong Ha
    • Journal of Radiation Protection and Research
    • /
    • v.41 no.3
    • /
    • pp.237-244
    • /
    • 2016
  • Background: Korea Atomic Energy Research Institute is developing a fission product transport module for predicting the behavior of radioactive materials in the primary cooling system of a nuclear power plant as a separate module, which will be connected to a severe accident analysis code, Core Meltdown Progression Accident Simulation Software (COMPASS). Materials and Methods: This fission product transport (COMPASS-FP) module consists of a fission product release model, an aerosol generation model, and an aerosol transport model. In the fission product release model there are three submodels based on empirical correlations, and they are used to simulate the fission product gases release from the reactor core. In the aerosol generation model, the mass conservation law and Raoult's law are applied to the mixture of vapors and droplets of the fission products in a specified control volume to find the generation of the aerosol droplet. In the aerosol transport model, empirical correlations available from the open literature are used to simulate the aerosol removal processes owing to the gravitational settling, inertia impaction, diffusiophoresis, and thermophoresis. Results and Discussion: The COMPASS-FP module was validated against Aerosol Behavior Code Validation and Evaluation (ABCOVE-5) test performed by Hanford Engineering Development Laboratory for comparing the prediction and test data. The comparison results assuming a non-spherical aerosol shape for the suspended aerosol mass concentration showed a good agreement with an error range of about ${\pm}6%$. Conclusion: It was found that the COMPASS-FP module produced the reasonable results of the fission product gases release, the aerosol generation, and the gravitational settling in the aerosol removal processes for ABCOVE-5. However, more validation for other aerosol removal models needs to be performed.

Determination of escape rate coefficients of fission products from the defective fuel rod with large defects in PWR

  • Pengtao Fu
    • Nuclear Engineering and Technology
    • /
    • v.55 no.8
    • /
    • pp.2977-2983
    • /
    • 2023
  • During normal operation, some parts of the fission product in the defective fuel rods can release into the primary loops in PWR and the escape rate coefficients are widely used to assess quantitatively the release behaviors of fission products in the industry. The escape rate coefficients have been standardized and have been validated by some drilling experiments before the 1970s. In the paper, the model to determine the escape rate coefficients of fission products has been established and the typical escape rate coefficients of noble gas and iodine have been deduced based on the measured radiochemical data in one operating PWR. The result shows that the apparent escape rate coefficients vary with the release-to-birth and decay constants for different fission products of the same element. In addition, it is found that the escape rate coefficients from the defective rod with large defects are much higher than the standard escape rate coefficients, i.e., averagely 4.4 times and 1.8 times for noble gas and iodine respectively. The enhanced release of fission products from the severe secondary hydriding of several defective fuel rods in one cycle may lead to the potential risk of the temporary shutdown of the operating reactors.

CONCENTRATION CONTOURS IN LATTICE AND GRAIN BOUNDARY DIFFUSION IN A POLYCRYSTALLINE SOLID

  • Kim, Yongsoo;Wonmok Jae;Saied, Usama-El;Donald R. Olander
    • Proceedings of the Korean Nuclear Society Conference
    • /
    • 1995.05a
    • /
    • pp.707-712
    • /
    • 1995
  • Grain boundary diffusion plays significant role in the fission gas release, which is one of the crucial processes dominating nuclear fuel performance. Gaseous fission products such as Xe and Kr generated inside fuel pellet have to diffuse in the lattice and in the grain boundary before they reach open space in the fuel rod. In the mean time, the grains in the fuel pellet grow and shrink according to grain growth kinetics, especially at elevated temperature at which nuclear reactors are operating. Thus the boundary movement ascribed to the grain growth greatly influences the fission gas release rate by lengthening or shortening the lattice diffusion distance, which is the rate limiting step. Sweeping fission gases by the moving boundary contributes to the increment of the fission gas release as well. Lattice and grain boundary diffusion processes in the fission gas release can be studied by 'tracer diffusion' technique, by which grain boundary diffusion can be estimated and used directly for low burn-up fission gas release analysis. However, even for tracer diffusion analysis, taking both the intragranular grain growth and the diffusion processes simultaneously into consideration is not easy. Only a few models accounting for the both processes are available and mostly handle them numerically. Numerical solutions are limited in the practical use. Here in this paper, an approximate analytical solution of the lattice and stationary grain boundary diffusion in a polycrystalline solid is developed for the tracer diffusion techniques. This short closed-form solution is compared to available exact and numerical solutions and turns out to be acceptably accurate. It can be applied to the theoretical modeling and the experimental analysis, especially PIE (post irradiation examination), of low burn up fission. gas release.

  • PDF