• Korean Journal of Biological Psychiatry
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• v.27 no.1
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• pp.27-35
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• 2020

Objectives Ketamine has been reported to have antidepressant effects or psychotomimetic effects. The aim of this study was to investigate the behavioral effects of ketamine treatment at various sub-anesthetic doses in adolescent and adult naïve mice. Methods In each experiment for adolescent and adult mice, a total of 60 male Institute of Cancer Research mice were randomly divided into 6 groups, which were intraperitoneally treated with physiological saline, 10, 20, 30, 40, and 50 mg/kg ketamine for consecutive 3 days. At 1 day after last injection, the locomotor and depressive-like behaviors were evaluated in mice, using open field test (OFT) and forced swim test (FST), respectively. Results In case of adolescent mice, ketamine dose was negatively correlated with total distance traveled in the OFT (Spearman's rho = -0.27, p = 0.039). In case of adult mice, we found significant positive correlation between ketamine dose and duration of immobility in the FST (Spearman's rho = 0.45, p < 0.001). Immobility time in the 50 mg/kg ketamine-treated mice was significantly higher compared to the saline-treated mice (Dunnett's post-hoc test, p = 0.012). Conclusions We found that the repeated treatment with ketamine could decrease the locomotor or prolong the duration of immobility in mice as the dose of ketamine increased. Our findings suggest that sub-anesthetic doses of ketamine might induce schizophrenia-like negative symptoms but not antidepressant effects in naïve laboratory animals.

• Journal of Digital Convergence
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• v.20 no.5
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• pp.227-232
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• 2022

This study is an exploratory study on the sustainable management of MICE events, and was conducted using the FGI method. Twelve experts in the MICE field, industry, and academia were selected as the subjects of the study. The reason is that understanding and specialty of those targets provides research reliability and validity. The study period was 3 months from June to August 2021. As a result, it is very important to prepare a sustainable development strategy in the MICE industry, and in particular, the need for guidelines to be practiced during event operation from the organizer's point of view was derived. In addition, to derive items that can be used in practice based on the theoretical basis, and it was necessary to derive research results using internationally recognized Sustainable Development Goals (UNSDGs) and sustainable MICE research developed in the fields of tourism and MICE. Therefore, through the verification of such experts in the field of MICE, theoretical and practical guidelines from the perspective of the organizer that can be used when holding MICE were developed. The results of the study will provide implications for establishing more effective strategies for hosting sustainable MICE events in the future.

• Journal of the Korean Data and Information Science Society
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• v.7 no.2
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• pp.247-256
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• 1996

In this paper, we applied bayesian hierarchical model to analyze the field mice example introduced by Demster et al.(1981). For this example, we use Gibbs sampler method to provide the posterior mean and compared it with LSE(Least Square Estimator) and MLR(Maximum Likelihood estimator with Random effect) via the EM algorithm.

• Animal Systematics, Evolution and Diversity
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• v.2 no.1
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• pp.1-10
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• 1986

문경산 흰 넓적다리 붉은 쥐, Apodemus peninsulae peninsulae, 의 염색체 핵형 분석과 단변량 및 다변량분석방법들을 사용한 등줄쥐, Apodemus agrarius coreae, 와의 형태적 형질의 비교를 하였다. 흰 넓적다리 붉은 쥐의 염색체수는 2n=50-54R지 수적 변이를 보였다. 차단부 염색체의 수는 48개로 개체간에 일정하였으나 , 중부 염색체의 수는 2-6개의 변이가 나타났다. 형태적 형질의 분석결과는 등줄쥐보다 흰 넓적다리 붉은 쥐가 크다고 판정되었으며 가장 구별이 잘 되는 경구개의 길이였다.

• Journal of Korean Society of Forest Science
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• v.70 no.1
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• pp.55-62
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• 1985

This study was made on bamboo shoot's damage of Phyllostachys edulis by field mice in Jinju, Gyeongsangnam-do, and grasped the inhabitation environment by the analysis of around and lower vegetation in damaged bamboo stands, and made clear the species of field mice in damaged bamboo stand, the damaged degree and rate, therefore, were put in practice for contribution with damage prevention and extermination. The results were summarized as follows; The damaged degree were influenced by inhabitation environment and stand density around damaged bamboo stands. The damaged degree were shown 4,359.1 g with 7.1 shoots per. ha and the rate 0.23%. The damage season were from the middle of April to the middle and end of May, the most damaged season was about April 23. The length of damaged bamboo shoot was mean 28.12 cm, the inside diameter 7.49 cm, the weight 613.96 g. The damaged type of parts was shown to more numerous overland and surface damaged type of three types; overland, surface and underground damaged type. The field mice to be captured in damaged bamboo stand were three species; Apodemus agrarius coreae, Mus molossinus and Crocidura lasiura, the species of main damage was Apodemus agrarius coreae of captured Rodentia's 2 species. Crocidura lasiura in order Insectivora was found to inhabitate for the first time at southern region in Korea.

• Microbiology and Biotechnology Letters
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• v.14 no.4
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• pp.325-328
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• 1986

The lethality to Pieris raepi larvae and the safety tests to mice of the endotoxin crystals and the pesticide of B thuringiensis serovar kurstaki were carried out. The LD50 of the endotoxin (3.9$\times$10$^9$ spores/$m{\ell}$) appeared to be 1$\mu$g and that of the pesticide (2.6$\times$10$^9$ spores/$m{\ell}$) was about 9 $\mu$g. When the endotoxin solution and the pesticide were injected to the mice's intraperitoneal cavities, 10 to 20% of the mite were dead. Also in the case of intracerebral injection 20% of the mice were dead at the doses of 7.8$\times$10$^3$ spores and 100% of the mice were dead at the concentration of 7.8$\times$10$^8$ spores. but the mice in the oral, subcutaneous and inhalation treatment groups were safe and healthy. When the pesticide applied to the cabbage field for raepi larvae, 52 to 65% of the larvae in the field were killed in 4 days postapplication.

• Korea Science and Art Forum
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• v.37 no.2
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• pp.35-46
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• 2019

The purpose of this study was to develop a hybrid model forecasting the optimal number of employees for the hotel MICE and investigate indicators' reliability and validity empirically. The dominant approach of manpower planning has long been conducted based on heuristic experience in the field of Hotel and MICE. There is little research on the manpower planning and forecasting in the hotel and MICE studies. However, it is significantly important to ensure how many the optimal number of employees are calculated to meet the goals of the company as well as the expectation of their customers. A focus group interview was used to collect data through a series of surveys. A total of 289 samples were collected to test validity of finalized indicators for forecasting the optimal number of employees for the Hotel MICE. The study developed 15 quantitative indicators and 19 qualitative indicators to forecasting the optimal number of employees for the Hotel MICE, based on three types of groups such as 'service-oriented', 'stability-oriented', and 'profitability-oriented' hotel company The study revealed the econometrics formula for the practical application for this field.

• Parasites, Hosts and Diseases
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• v.52 no.4
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• pp.419-423
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• 2014

The present study was performed to know the infection status of intestinal helminths in a most common species of field mice, Apodemus agrarius, from 2 southern regions of Korea. Total 133 and 103 mice were collected by the mouse trap in Hapcheon-gun, Gyeongsangnam-do and Gurye-gun, Jeollanam-do, respectively, from July 2005 to June 2006. The small intestine of each mouse was resected and longitudinally opened with a pair of scissors. The intestinal contents were washed with 0.85% saline until the supernatant became clear. Helminths were collected with naked eyes or under a stereomicroscope from the sediment of the intestinal content. More than 11 species of helminths (4 nematode spp., 5 trematode spp., and 2 cestode spp.) were recovered. Among these, heligmosomoid nematodes (97.5%) was the most highly and heavily infected species. As the members of trematodes, Plagiorchis muris, Brachylaima sp., Echinostoma hortense, Echinostoma cinetorchis, and unidentified echinostome larvae were found in the small intestines of 35 (14.8%), 12 (5.1%), 6 (2.5%), 1 (0.4%), and 1 (0.4%) mice respectively. Two species of tapeworms, Hymenolepis nana and Hymenolepis diminuta were also detected in 79 (33.5%) and 21 (8.9%) mice, respectively. Conclusively, heligmosomoid nematodes were the most prevalent (dominant) species among more than 11 helminth species detected, and Brachylaima sp. fluke is newly added in the list of intestinal trematodes in Korea.

• Journal of Environmental Science International
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• v.8 no.4
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• pp.515-523
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• 1999

Nine trace metals (Zn, Fe, Al, Pb, Mn, Cu, Ni, Cr, and Cd) and Se concentrations were determined in organs and tissues(muscle, bone, kidney, liver and skin) of the striped field mice, Apodemus agrarius collected at Daejeo-dong, Pusan city and the Sorak Mt., Kangwon Province. All the trate elements were detected from all the mice examined. As for the metal concentrations in the mice from Daejeo-dong, Zn, Fe, Al, Mn, Ni and Cr were significantly higher than those in Sorak Mt.(p<0.05), suggesting that pesticides including Zn and factory wastes containing several metals might contaminated the environment of Daejeo-dong. As regards the element concentrations in each organ and tissue, Fe, Al, Pb, Mn, Cu, Cr and Cd concentrations were high in liver or kidney; Zn in skin and bone; Ni in bone, skin and kidney; and Se in muscle, liver and skin in all the mice examined. There were significant differences(p<0.05) between juveniles and adults in average concentration of metals(Zn, Fe, Pb, Mn, Ni, and Cd) in every organs and tissues of mice collected at Daejeo-dong. Much higher average levels of metals in juveniles indicate that considerable burdens fo metals might be transferred through the placenta. However, there were no significant differences between males and females, and between young and old adults in average metal concentrations, which suggests that the mice might accumulate the metals during their life time, although they might excrete the metals not only through reproductive activities, such as parturition, lactation and ejaculation of semen, but also through molting, judging from higher accumulating ratios of most metals in skin of adults than of juveniles.

• Animal Systematics, Evolution and Diversity
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• v.5 no.1
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• pp.1-12
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• 1989

Samples of striped field mice, Apodemus agrarius Pallas, from eight localities in s southwestern islands and coasts in Korea were collected and analyzed together with samples from the mainland and Jeju island. In chromosomal analyses no variation was revealed in karyotypes among samples from Korea. In morphometric analyses samples from Wan and Bogil islands formed a large-size g group (A. agrarius chejuensis) with those from Jeju island, whereas samples from Jin and H Hajo islands formed a small-size group (A. agrarius coreae) with those from the mainland including southwestern coasts It is supposed that small-size population of striped field mice in Wan and Bogil islands w were extinct and replaced by large-szie population of striped field mice immigrated from Jeju island by humans.