• KSBB Journal
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• v.24 no.6
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• pp.591-597
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• 2009

B-type natriuretic peptide is a neurohormone secreted in the cardiac ventricles. BNP levels are elevated in patients with ventricular dysfunction. Therefore, the concentration of BNP is important factor to reflect diagnosis and prognosis for cardiovascular disease. In this respect, anti-BNP scFv is an urgent requirement for early diagnosis in the field of biosensor. Herein, the genetic codes of anti-BNP scFv were chemically synthesized and cloned into both pET22b (+) and pColdⅣ vector, respectively. The recombinant scFv was successfully expressed as a functional form in cytoplasm of E. coli and detected through Western blot and ELISA. The highest level of functional expression of anti-BNP scFv was achieved using pET22b (+) vector at $15^{\circ}C$ by addition of 0.1 mM IPTG. Additionally, being exposed to both BNP and ANP, anti-BNP scFv specifically captured only BNP. Therefore, anti-BNP scFv expressed in this study will be applied to measure the concentration of BNP as a diagnostic recognition molecule.

• Korean Journal of Health Education and Promotion
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• v.27 no.5
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• pp.63-71
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• 2010

Objectives: The field of health education is still relatively new and is therefore evolving and developing rapidly throughout the world. Many countries' certification programs are still being created. This paper will discuss on the US CHES system of regulation, accreditation, and implementation for the future development of international health education programs. Methods: This article focuses on the United States CHES credentialing program, specifically on its historical development and the roles, employment settings and socioeconomic demographics of current CHES professionals through literature review. Results: The roles and skills required vary by employment setting, with seven universally recognized responsibilities of health educators. There are also 35 key competencies which are crucial to the role of the health educator, with 163 sub-competencies performed by all health educators. The employment of health educators will increase from 62,000 in 2006 to 78,000 in 2016. As the costs of healthcare increase, employers are projected to hire more health educators to decrease healthcare costs through prevention and early detection of chronic illnesses. Community health non-profit agencies, academia, healthcare (hospital/clinic), schools, government/government contracting, and businesses are some of the most widespread employment settings for health educators in the United States. Conclusion: Better understanding of this longstanding and successful program will benefit countries developing their own certification system. The variety and specificity of the information on the US CHES program may be of value as South Korea continues to develop its Korean CHES program.

• The Journal of the Korea institute of electronic communication sciences
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• v.9 no.2
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• pp.219-230
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• 2014

There are many economical and industrial as well as social demands enabling smart management of railway vehicle including parts management by introducing RFID system in railway vehicle. In this paper, overseas researches and developments which use cases of RFID were investigated and analyzed. In this process, cases of various industries adopting RFID technology as well as cases of railway part were investigated. RFID system is used mainly for railway vehicle position detection and identification of vehicles in the field of railway. Also there are cases of application on traceability management of railway vehicle parts. The system in which RFID technology can be applied to railway parts management and traceability management is necessary for smart management of domestic railway vehicle.

• Journal of the Korean earth science society
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• v.31 no.6
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• pp.563-572
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• 2010

Both multi-channel temperature monitoring and geophysical electric survey were performed together for an embankment to assess the leakage zone. Temperature variation according to space and time on the inner parts of engineering constructions (e.g.: dam and slope) can be basic information for diagnosing their safety problem. In general, as constructions become superannuated, structural deformation (e.g.: cracks and defects) could be generated by various factors. Seepage or leakage of water through the cracks or defects in old dams will directly cause temperature anomaly. This study shows that the position of seepage or leakage in dam body can be detected by multi-channel temperature monitoring using thermal line sensor. For that matter, diverse temperature monitoring experiments for a leakage physical model were performed in the laboratory. In field application of an old earth fill dam, temperature variations for water depth and for inner parts of boreholes located at downstream slope were measured. Temperature monitoring results for a long time at the bottom of downstream slope of the dam showed the possibility that temperature monitoring can provide the synthetic information about flowing path and quantity of seepage of leakage in dam body. Geophysical data by electrical method are also added to help interpret data.

• Transactions on Electrical and Electronic Materials
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• v.14 no.4
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• pp.211-215
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• 2013

Partial discharge diagnosis techniques using ultra high frequencies do not affect load movement, because there is no interruption of power. Consequently, these techniques are popular among the prevention diagnosis methods. For the first time, this measurement technique has been applied to the GIS, and has been tested by applying an extra high voltage switchboard. This particular technique makes it easy to measure in the live state, and is not affected by the noise generated by analyzing the causes of faults ? thereby making risk analysis possible. It is reported that the analysis data and the evaluation of the risk level are improved, especially for poor location, and that the measurement of Ultra high frequency (UHF) partial discharge of the real live wire in industrial switchgear is spectacular. Partial discharge diagnosis techniques by using the Ultra High Frequency sensor have been recently highlighted, and it is verified by applying them to the GIS. This has become one of the new and various power equipment techniques. Diagnosis using a UHF sensor is easy to measure, and waveform analysis is already standardized, due to numerous past case experiments. This technique is currently active in research and development, and commercialization is becoming a reality. Another aspect of this technique is that it can determine the occurrences and types of partial discharge, by the application diagnosis for live wire of ultra high voltage switchgear. Measured data by using the UHF partial discharge techniques for ultra high voltage switchgear was obtained from 200 places in Gumi, Yeosu, Taiwan and China's semiconductor plants, and also the partial discharge signals at 15 other places were found. It was confirmed that the partial discharge signal was destroyed by improving the work of junction bolt tightening check, and the cable head reinforcement insulation at 8 places with a possibility for preventing the interruption of service. Also, it was confirmed that the UHF partial discharge measurement techniques are also a prevention diagnosis method in actual industrial sites. The measured field data and the usage of the research for risk assessment techniques of the live wire status of power equipment make a valuable database for future improvements.

• KIPS Transactions on Software and Data Engineering
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• v.7 no.3
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• pp.77-90
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• 2018

Software Defect Prediction (SDP) is a field of study that identifies defective modules. With insufficient local data, a company can exploit Cross-Project Defect Prediction (CPDP), a way to build a classifier using dataset collected from other companies. Most machine learning algorithms for SDP have used more than one parameter that significantly affects prediction performance depending on different values. The objective of this study is to propose a parameter selection technique to enhance the performance of CPDP. Using a Harmony Search algorithm (HS), our approach tunes parameters of cost-sensitive boosting, a method to tackle class imbalance causing the difficulty of prediction. According to distributional characteristics, parameter ranges and constraint rules between parameters are defined and applied to HS. The proposed approach is compared with three CPDP methods and a Within-Project Defect Prediction (WPDP) method over fifteen target projects. The experimental results indicate that the proposed model outperforms the other CPDP methods in the context of class imbalance. Unlike the previous researches showing high probability of false alarm or low probability of detection, our approach provides acceptable high PD and low PF while providing high overall performance. It also provides similar performance compared with WPDP.

• Korean Journal of Remote Sensing
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• v.36 no.5_1
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• pp.835-846
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• 2020

Recent severe climate changes and extreme weather events have caused the uncommon types of forest ecosystem disturbances such as hails and gypsy moths. This paper describes the analysis of the forest ecosystem disturbances using ISODATA (Iterative Self-organizing Data Analysis Technique Algorithm) with the RapidEye and Sentinel-2 images, regarding the cases of the hail damages in Hwasun in 2017 and the gypsy moth damages in the Chiak Mountain in 2020. In the case of hail damages, the comparison of the June image of this study and the July field survey of the previous study showed that the damage severity increased from June to July as the drought overlapped after the trees were injured by the hails. In the case of gypsy moths, significant leaf damages were found from the image of June, and the damages were mainly distributed at the low-altitude slope near Wonju City. We made sure that satellite remote sensing is a very effective method to detect various and unusual forest ecosystem disturbances caused by climate change. Also, it is expected that the Korean Medium Satellite for Agriculture and Forestry scheduled to launch in 2024 can be actively utilized to monitor such forest ecosystem disturbances.

• Journal of the Korean Institute of Gas
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• v.21 no.5
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• pp.1-8
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• 2017

Currently gas safety management in the industrial field has been done by LDAR as contact method or methane leak detector as non-contact method. But LDAR method requires a lot of man-power and methane leak detector have the limitation of methane only. Therefore the Research on the OGI(optical gas image) has big attention by industry. This research was undertaken to see the effect of background temperature difference of gas cloud on the clarity of OGI. The background temperature control panel was constructed to cool down the background temperature. OGI was taken at the various methane gas ejection rate and the designed temperature difference. The experimental results showed that the OGI(when the temperature difference is $-6^{\circ}C$) is more clear thane the OGI(when the temperature difference is zero). To quantify the clarity difference, MATLAB's RGB analysis method was employed. The RGB value of the OGI at ${\Delta}T-6^{\circ}C$ was 20% lower than the OGI at ${\Delta}T0^{\circ}C$. The clarity difference by T difference can be explained by the total radiation law. When the background temperature of the gas is lower than the air temperature, the radiation energy coming into the OGI lens is increasing. As the energy is increasing, the OGI image becomes clear.

• Journal of the Korean Society of Radiology
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• v.3 no.4
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• pp.29-33
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• 2009

Recently, the compound materials(a-Se, $HgI_2$, PbO, CdTe, $PbI_2$, etc.) that are used in flat panel x-ray imager have been studied for digital x-ray imaging. In this paper, the signal detection properties of $HgI_2$ and a-Se conversion layer, are compared. The thick $HgI_2$ film is fabricated by special particle-in-binder method and the conventional vacuum thermal evaporation is used for a deposition of a-Se film. And an electrical characteristic measurements were investigated about leakage current, signal response property and x-ray sensitivity. From the experimental results show that the $HgI_2$ film has a low operation voltage and high signal generation than that of a-Se.

• The Korean Journal of Pesticide Science
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• v.4 no.1
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• pp.1-10
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• 2000

The purpose of this study is to establish the assessment techniques of hazardous chemicals by the development of analytical method of biological samples. In this study, we have developed an extraction method of nine pesticides used for rice paddy that resulted in high recovery from the spiked human urine by the liquid-liquid extraction with diethyl ether at pH 7.0. Calibration curve obtained from each pesticide standard using by gas chromatography/mass spectrometry/selected ion monitoring has shown good linearity and detection limits were the range of $0.4{\sim}2.0$ ng/mL in urine. As a biological monitoring, urine samples of local farmers exposed directly to nine pesticides in the field were collected and analyzed by GC/MS. Of the tested pesticides, metabolites of phenthoate assumed were identified by GC/MS analysis. No parent compound was detected.