• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1987년도 Proceedings of Korea-Japan Panax Ginseng Symposium 1987 Seoul Korea
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• pp.20-28
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• 1987

To clarify central mechanisms of ginsenosides, changes in ingestive and ambulatory behaviors were investigated in rats after single or continuous infusion into the third cerebroventricle or various hypothalamic loci. Following single infusion into the third cerebroventricle, ginsenoside Rbl at doses of 0.05, 0.10 and 0.20 $\mu$mol dose-dependently decreased food intake. None of the doses tested affected ambulation. Drinking suppression was only observed at the maximum dose of 0.20 $\mu$mol. Equimolar injections into the peritoneum had no effects on ingestive behavior or ambulation. These findings indicated that ginsenoside Rbl specifically and centrally inhibited food intake. According to analyses of daily feeding patterns, this feeding suppression was the result of a decrease in meal size, not from changes in the postprandial intermeal interval or eating speed. The suppressed food intake was accompanied by hyperglycemia, leaving plasma insulin unaffected. Unilateral micro injection of 0.01 u mot ginsenoside Rb, into the ventromedial hypothalamus specifically decreased food intake, although equimolar injection into the lateral hypothalamic area did not affect food intake. Following continuous infusion of Rg, into the third cerebroventricle, the feeding inhibition due to surgical operation was attenuated. Rbs administered by the same procedure abolished the toxic effect of toxohormone-L on food intake. Taken together, these findings suggest that ginsenoside as a whole may have pharmacological potency to maintain feeding at a certain physiological level.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1996년도 한국자동제어학술회의논문집(국내학술편); 포항공과대학교, 포항; 24-26 Oct. 1996
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• pp.952-955
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• 1996

It is difficult to determine the feeding rate of coagulant in water treatment process, due to nonlinearity, multivariables and slow response characteristics etc. To deal with this difficulty, the fusion of genetic algorithms and fuzzy inference system was used in determining of feeding rate of coagulant. The genetic algorithms are excellently robust in complex operation problems, since it uses randomized operators and searches for the best chromosome without auxiliary information from a population consists of codings of parameter set. To apply this algorithms, we made the look up table and membership function from the actual operation data of water treatment process. We determined optimum dosages of coagulant (PAC, LAS etc.) by the fuzzy operation, and compared it with the feeding rate of the actual operation data.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2001년도 ICCAS
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• pp.123.2-123
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• 2001

It is difficult to determine the feeding rate of coagulant in the water treatment plant, due to nonlinearity, multivariables and slow response characteristics, etc. To deal with this difficulty, the neuro-fuzzy system and the genetic-fuzzy system were used in determining the feeding rate of the coagulant. The fuzzy system is excellently robust in multi-variables and nonlinear problems. Therefore it uses basic algorithm, but it is difficult to construct of the fuzzy parameter such as the rule table and the membership function, Therefore we made the neuro-fuzzy system and the genetic-fuzzy system with the fusion of learning algorithms and compared the performance of the two fuzzy systems. To apply these algorithms, we made the rule table, membership function from the actual operation data of the water treatment plant. We determined optimized feeding rate of coagulant using the fuzzy operation, and also compared ...

• Asian-Australasian Journal of Animal Sciences
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• 제8권5호
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• pp.523-527
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• 1995

Two on farm feeding trials were conducted at the Pabna milkshed area during July to October 1993, to evaluate the response of feeding urea molassesed straw (UMS) on milk production of Pabna milking cows and its economics. A feeding trial of 60 days with 50 Pabna milking cows showed that the cows fed UMS as a replacer of dry straw increased daily milk yield by 1.37 litre. Moreover, it reduced the daily requirement of concentrate by 1.0 kg/head. In the second trial, a herd of 52 animals including 14 milking cows were fed UMS in place of traditionally used dry straw. Introduction of UMS increased the milk production by 1.0 litre/cow/day and saved concentrate by 1.5 kg/cow daily. Urea molassesed straw can safely and economically be fed to lactating cows.

• 제어로봇시스템학회논문지
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• 제5권7호
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• pp.876-882
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• 1999

It is difficult to determine the feeding rate of coagulant in the water treatment process, due to nonlinearity, multivariables and slow response characteristics, etc. To deal with this difficulty, the genetic-fuzzy system was used in determining the feeding rate of the coagulant. The genetic algorithms are excellently robust in complex optimization problems. Since it uses randomized operators and searches for the best chromosome without auxiliary informations from a population consists of codings of parameter set. To apply this algorithms, we made the lookup table and membership function from the actual operation data of the water treatment process. We determined optimum dosages of coagulant(LAS) by the fuzzy operation, and compared it with the feeding rate of the actual operation data.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1994년도 추계학술대회 논문집
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• pp.597-601
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• 1994

In this paper, we have describes about the reationships between a core gap and a feeding velocity, an amplitude and the core gap by the exciting forc, the parts movement and a bowl materials, and the feeding veocity and the parts in the parts feeder. The main results as compared with the stainless and the aluminum materials are as follow : 1) The mean feeding velocity by bowl material shown more relative proportion in the STS304 to the exciting voltage than the C%AV 2) IN the exciting voltage, the response time for the aluminum material is slow, but the stainless is sensibility. 3) An exciting voltage is rised by an increase of the weight, but an amplitude has been in the range between 23 .mu.m through 40 .mu. m.

• Molecules and Cells
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• 제40권5호
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• pp.331-338
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• 2017

Regulation of feeding is essential for animal survival. The pharyngeal sense organs can act as a second checkpoint of food quality, due to their position between external taste organs such as the labellum which initially assess food quality, and the digestive tract. Growing evidence provides support that the pharyngeal sensory neurons regulate feeding, but much is still unknown. We found that a pair of gustatory receptor neurons in the LSO, a Drosophila adult pharyngeal organ which expresses four gustatory receptors, is involved in feeding inhibition in response to high concentrations of sodium ions. RNAi experiments and mutant analysis showed that the gustatory receptor Gr2a is necessary for this process. This feeding preference determined by whether a food source is perceived as appetizing or not is influenced by nutritional conditions, such that when the animal is hungry, the need for energy dominates over how appealing the food source is. Our results provide experimental evidence that factors involved in feeding function in a context-dependent manner.

• 한국수의병리학회지
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• 제2권1호
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• pp.37-46
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• 1998

It has been known that $\gamma$-irradiation usually induces cell death in regenerating stem cell in normal tissues like skin, intestine and hematopoietic organ. The experiment were carried out to evaluate the early response of radiation injury in radiosensitive and intermediate radiosensitive tissues in feeding and starving rats with the doses of 3.5 and 7.0 Gy. The results of the study showed that the histological phenomenon was apoptosis in the doses of the radiation as the early response of tissue injury. Apoptosis were showed organ-specific and cellular specific responses suggesting that the selection of apoptosis be exactly focused on highly renewal organs and cells. It was interesting that the rats starved for 72 hours prior to irradiation induced less apoptosis in liver than fed rats. As for cellular responses it appeared that apoptotic cells were mostly distributed in ductal or periportal cells in liver of feeding rats unlikely in liver of Starving rots which showed no difference in zonal distribution. In salivary gland apoptotic cells in fed rats were highly induced in intercalating and ductal cell population than in acinar cell population although unlikely in starved rats. This study showed the value of apoptosis using the detection system of TUNEL for evaluating cellular damage after radiation injury and the diminished effect of starvation on cell damage after ionizing irradiation.

• 한국가금학회지
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• 제46권1호
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• pp.1-10
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• 2019

닭의 성장과정에서 어린 병아리의 발달에 가장 결정적인 시간으로 인식되는 시점은 부화 전 수일부터 부화 후 수일간이다. 부화 전후의 충분한 영양소 공급은 배아의 최종 발달과 병아리의 초기성장에 결정적 기여를 한다고 볼 수 있다. In ovo feeding에 의한 탄수화물 또는 아미노산의 공급은 부화 전 후의 소화장기 발달에 긍정적으로 작용한다. Prebiotics과 synbiotics 등에 대한 in ovo 주입은 건강한 미생물 균총 형성 등을 제공하여 영양적, 면역적 측면에서 좋은 결과들을 볼 수 있지만, 연구 결과의 수적 제한과 in ovo 주입의 양과 주입 부위 및 주입시기 등에 대한 추가적인 연구가 요구된다. 탄수화물을 이용한 in ovo feeding은 부화시 체중 증가를 보이지만 육계의 부화 후 능력에는 크게 영향을 보이지 않으며, 탄수화물 주입에 따른 부화율 감소는 기술적 요인(최적 농도, 주입 장소, 부피 등)이 크게 작용하는 것으로 보인다. In ovo feeding에 의한 아미노산 공급은 병아리의 세포성 면역과 체액성 면역을 높여 초기 면역 향상에 도움이 되는 것으로 판단된다. In ovo feeding은 부화 전후의 최적의 영양소 공급과 면역력 증진 및 절식에 따른 병아리의 스트레스를 완화시켜주는 실용적인 기술이 될 수 있다.

• Journal of Microbiology and Biotechnology
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• 제32권7호
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• pp.902-910
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• 2022

The ginsenoside compound K (C-K) is widely used in traditional medicines, nutritional supplements, and cosmetics owing to its diverse pharmacological activities. Although many studies on C-K production have been conducted, fermentation is reported to produce C-K with low concentration and productivity. In the present study, addition of an inducer and optimization of the carbon and nitrogen sources in the medium were performed using response surface methodology to increase the C-K production via fermentation by Aspergillus tubingensis, a generally recognized as safe fungus. The optimized inducer and carbon and nitrogen sources were 2 g/l rice straw, 10 g/l sucrose, and 10 g/l soy protein concentrate, respectively, and they resulted in a 3.1-fold increase in the concentration and productivity of C-K (0.22 g/l and 1.52 mg/l/h, respectively) compared to those used before optimization without inducer (0.071 g/l and 0.49 mg/l/h, respectively). The feeding methods of American ginseng extract (AGE), including feeding timing, feeding concentration, and feeding frequency, were also optimized. Under the optimized conditions, A. tubingensis produced 3.96 mM (2.47 g/l) C-K at 144 h by feeding two times with 8 g/l AGE at 48 and 60 h, with a productivity of 17.1 mg/l/h. The concentration and productivity of C-K after optimization of feeding methods were 11-fold higher than those before the optimization (0.22 g/l and 1.52 mg/l/h, respectively). Thus, the optimization for the feeding methods of ginseng extract is an efficient strategy to increase C-K production. To our knowledge, this is the highest reported C-K concentration and productivity via fermentation reported so far.