• BMB Reports
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• 제51권4호
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• pp.167-173
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• 2018

Experimental results obtained from research using only one sex are sometimes extrapolated to both sexes without thorough justification. However, this might cause enormous economic loss and unintended fatalities. Between years 1997 and 2000, the US Food and Drug Administration suspended ten prescription drugs producing severe adverse effects on the market. Eight of the ten drugs caused greater health risks in women. Serious male biases in basic, preclinical, and clinical research were the main reason for the problem. This mini-review will describe why and how funding organizations such as the European Commission, the Canadian Institutes of Health Research, and the US National Institutes of Health have tried to influence researchers to integrate sex/gender not only in clinical research, but also in basic and preclinical research. Editorial policies of prominent journals for sex-specific reporting will also be introduced, and some considerations in integrating sex as a biological variable will be pointed out. To produce precise and reproducible results applicable for both men and women, sex should be considered as an important biological variable from basic and preclinical research.

• Safety and Health at Work
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• 제1권2호
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• pp.107-111
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• 2010

This paper provided a brief summary of the current strategic goals, activities, and impacts of the NIOSH (National Institute for Occupational Safety and Health) occupational injury research program. Three primary drivers (injury database, stakeholder input, and staff capacity) were used to define NIOSH research focuses to maximize relevance and impact of the NIOSH injury-prevention-research program. Injury data, strategic goals, program activities, and research impacts were presented with a focus on prevention of four leading causes of workplace injury and death in the US: motor vehicle incidents, falls, workplace violence, and machine and industrial vehicle incidents. This paper showcased selected priority goals, activities, and impacts of the NIOSH injury prevention program. The NIOSH contribution to the overall decrease in fatalities and injuries is reinforced by decreases in specific goal areas. There were also many intermediate outcomes that are on a direct path to preventing injuries, such as new safety regulations and standards, safer technology and products, and improved worker safety training. The outcomes serve as an excellent foundation to stimulate further research and worldwide partnership to address global workplace injury problems.

• 한국철도학회논문집
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• 제7권4호
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• pp.302-306
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• 2004

Many long railway tunnels without emergency evacuation system or ventilation system are under construction or in-use in Korea. In the case of tunnel-fire, many fatalities are occur in current condition. Current safety level is estimated in this study, for the efficient investment on safety. But so many uncertainties in major input parameters make the safety estimation difficult. In this study, probabilistic techniques are applied for the consideration of uncertainties in major input parameters. As results of this study, accident scenarios and survival ratio under tunnel fire accident are determined for various conditions.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2006년도 추계학술대회 논문집
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• pp.1053-1058
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• 2006

Many railway safety measures reduce railway fatalities into half for last 10 years. But more improvement in railway safety is required to meet the social need after railway fire accident in Daegue. Reasonable railway safety index is needed to find out the weak point and efficiencies of various safety measures. But we still have only 2 kinds of safety index which are set for 10 years ago. In order to derive guideline for setting up safety index, we analyze accident cause, previous studies for railway safety improvement in Korea, and other countries safety plan. As a result some proposal for safety index was driven in this study.

• 한국건축시공학회지
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• 제6권4호
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• pp.53-60
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• 2006

Quality control and safety represent increasingly important concerns for project managers. In the worst case, failures may cause personal injuries or fatalities. Accidents during the construction process can similarly result in personal injuries and large costs. We present the results of a study designed to identify the tools that are most widely used and those that are associated with successful project management in general, and with effective project risk management in particular. The study is based on a questionnaire administered to a sample of project managers from construction enterprises. The response data was analyzed in order to find which tools are more likely to be used in the those organizations that report better project management performance and in those that value the contribution of risk management processes.

• International Journal of Automotive Technology
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• 제6권5호
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• pp.491-499
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• 2005

There are different types of vehicle impacts recorded every year, resulting in many injuries and fatalities. The severity of these impacts depends on the aggressivety and incompatibility of vehicle-to-roadside hardware impacts. The aim of this paper is to investigate and to enhance crashworthiness in the case of full barrier impact using a new idea of crash improvement. Two different types of smart structures have been proposed to support the function of the existing vehicle. The work carried out in this paper includes developing and analyzing mathematical models of vehicle-to-barrier impact for the two types of smart structures. It is proven from analytical analysis that the mathematical models can be used in an effective way to give a quick insight of real life crashes. Moreover, it is shown that these models are valid and flexible, and can be useful in optimization studies.

• Safety and Health at Work
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• 제1권1호
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• pp.11-18
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• 2010

In the UK, a person or organisation that creates risk is required to manage and control that risk so that it is reduced 'So Far As Is Reasonably Practicable (SFAIRP).' How the risk is managed is to be determined by those who create the risk. They have a duty to demonstrate that they have taken action to ensure all risk is reduced SFAIRP and must have documentary evidence, for example a risk assessment or safety case, to prove that they manage the risks their activities create. The UK Health and Safety Executive (HSE) does not tell organisations how to manage the risks they create but does inspect the quality of risk identification and management. This paper gives a brief overview of where responsibility for occupational health and safety lies in the UK, and how risk should be managed through risk assessment. The focus of the paper is three recent major UK incidents, all involving fatalities, and all of which were wholly avoidable if risks had been properly assessed and managed. The paper concludes with an analysis of the common failings of risk assessments and key actions for improvement.

• 한국안전학회지
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• 제36권5호
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• pp.36-42
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• 2021

Portable ladders are widely used as ascend and descend pathways and platforms for works at height at residential and industrial sites. In the last 10 years, 267 fatalities and 36,571 accidents related to portable ladders have been reported, suggesting a need to develop countermeasures to prevent such accidents. In this study, an in-depth focus group interview (FGI) was conducted with various stakeholders of portable ladders to survey the current usage and requirements for improving work safety. A new portable ladder called active platform ladder was developed based on the requirements suggested by the FGI. A stability test confirmed that the developed ladder is more stable than conventional ones, suggesting that it can reduce the fall accidents.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.118.2-118.2
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• 2003

Propofol(2, 6-diisopropylphenol) is rapid, short-acting intravenous anaesthetic agent. It is used for the induction and maintenance of general anaesthesia or sedation. The recommended doses are 2-2.5mg/kg given as a titration infusion over about 30min to achieve anaesthesia. Recently, we encountered 4 fatalities related to propofol. One death is a suicide by self-administered of propofol and the others are therapeutic misadventures during surgical care. The propofol level in the blood and tissues were determined by gas chromatographic analysis with mass spectral detection. (omitted)

• International Journal of Computer Science & Network Security
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• 제21권1호
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• pp.192-200
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• 2021

In the mid of the December 2019, the virus has been started to spread from China namely Corona virus. It causes fatalities globally and WHO has been declared as pandemic in the whole world. There are different methods which can fit such types of values which obtain peak and get flattened by the time. The main aim of the paper is to find the best or nearly appropriate modeling of such data. The three different models has been deployed for the fitting of the data of Coronavirus confirmed patients in Pakistan till the date of 20^th November 2020. In this paper, we have conducted analysis based on data obtained from National Institute of Health (NIH) Islamabad and produced a forecast of COVID-19 confirmed cases as well as the number of deaths and recoveries in Pakistan using the Logistic model, Gompertz model and Auto-Regressive Integrated Moving Average Model (ARIMA) model. The fitted models revealed high exponential growth in the number of confirmed cases, deaths and recoveries in Pakistan.