• 한방비만학회지
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• 제4권1호
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• pp.1-11
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• 2004

Objectives: The effects of peroxisome proliferator-activated receptor ${\gamma}2\;(PPAR{\gamma}2)$ Pro12Ala (P12A) polymorphism on body mass index (BMI) and type 2 diabetes are well documented; however, until now, only a few studies have evaluated the effects of this polymorphism on body fat distribution. This study was conducted to elucidate the effects of this polymorphism on computed tomography (CT)-measured body fat distribution and other obesity-related parameters in Korean female subjects. Methods & Results: The frequencies of $PPAR{\gamma}2$ genotypes were: PP type, 93.0%; PA type, 6.8%; and AA type, 0.2%. The frequency of the A allele was 0.035. Body weight (P .012), BMI (P .012), and waist-to-hip ratio (WHR) (P .001) were significantly higher in subjects with PA/AA compared with subjects with PP. When body composition was analyzed by bioimpedance analysis, lean body mass and body water content were similar between the 2 groups. However, body fat mass (P .003) and body fat percent (P .025) were significantly higher in subjects with PA/AA compared with subjects with PP. Among overweight subjects with BMI of greater than 25, PA/AA was associated with significantly higher abdominal subcutaneous fat (P .000), abdominal visceral fat (P .031), and subcutaneous upper and lower thigh adipose tissue (P .010 and .013). However, among lean subjects with BMI of less than 25, no significant differences associated with $PPAR{\gamma}2$ genotype were found, suggesting that the fat-accumulating effects of the PA/AA genotype were evident only among overweight subjects, but not among lean subjects. When serum lipid profiles, glucose, and liver function indicators were compared among overweight subjects, no significant difference associated with $PPAR{\gamma}2$ genotype was found. Changes in body weight, BMI, WHR, and body fat mass were measured among overweight subjects who finished a 1-month weight lose program of a hypocaloric diet and exercise; no significant differences associated with $PPAR{\gamma}2$ genotype were found. Conclusions: The results of this study suggest that the $PPAR{\gamma}2$ PA/AA genotype is associated with increased subcutaneous and visceral fat areas in overweight Korean female subjects, but does not significantly affect serum biochemical parameters and outcomes of weight loss programs.

• 한국식품영양학회지
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• 제12권3호
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• pp.312-319
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• 1999

This study was carried out to examine obesity and nutrition knowledge in male employees who had high educational background. The subjects in this study were 213 persons aged 20 to 40(52.6% among them were 20s) Ninety six percent of them graduated university. Most of them took exercise regularly and showed less smoking tends but drank frequently. Twenty two point one percent of the subjects had diseases specially gastrointestinal disease. anthropometric results were height:172.1cm; weight :70.5kg;BMI:23.8;fat mass:16.1kg; fat percentage :21.3% ;LBM :55.4kg ; and TBW : 40.9kg BMI and fat percent were used for screening obesity. According to BMI the normal group (20∼25) was 64.6% the oberweight group (25∼27) was 18.4% the underweight group (<20) was 9.9% and the obese group (>27) was 7.1% Based on fat percentage, the normal group (14%∼23%) was 58.5% the obese group(>23%) was 36.0% and the underweight group(<14%) was 6.5%. There was significant relationship be-tween age or marriage and BMI or fat percentage. But the rest of socio-dmographic and health-related factors didn't affect signifincantly. There was no difference in nutrition knowledge of subjects by obesity rate however obese group was more sensitive to the foods related to weight gain.

• 지역사회간호학회지
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• 제9권2호
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• pp.458-466
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• 1998

The purpose of this study is to investigate the differences in body fat distribution between obese boys and girls in high school and the relationship between the precent of body fat and the Broca Index. The survey of data was conducted from November 3rd to the 11th in 1997. The data were analyzed by the use of a mean, standard deviation and a Pearson's correlation coefficient. Measurements of the percentage of body fat and lean body mass were made by a Bioelectrical Impedence while height, weigh and the Broca index were measured by a fatness measuring system. First, measurements of height, weight and the Broca index were made by a fatness measuring system on 1,125 1st year students and 1,076 2nd year students. The result of measurements, 216 obese boys and 100 obese girls appeared to have above 10% of the Broca index. The result of this study can be summarized as follows: 1) Obese boys and girls were grouped by the level of the Broca index as follows: boys, 110-less than 120 60.0%, 120-less than 130 20.8%, 130-less than 140 11.1%, above 140 7.4%. ; girls, 110-less than 120 44.4%, 120-less than 130 32.0%, 130-less than 140 13.0%, above 140 11.0%. 2) Obese boys and girls were grouped by level of the percentage of body fat by Bioelectrical Impedence as follows: boys, less than 20% 5%, 20%-less than 25% 34.7%, above 25% 33.8% ; girls. less than 25% 15.0%, 25%-less than 30% 43.0%, above 30% 42.0%. 3) In obese boys the Broca index score appeared to be positively related to body weight(r = .741, p<.001), the percent of body fat(r=.604, p<.001), lean body mass(r=.375, p<.001), body fluid(r=.445, p<.001l). On the other hand the percent of body fat was not a significant correlation of lean body mass (r= -.074), body fluid(r= -.073). 4) In obese girls, the Broca index score appeared to be positively related to body weight(r= .693, p<.001), the percent of body fat(r=.645, p<.001), lean body mass(r=.531, p<.001), body fluid(r=.532, p<.01), and the percent of body weight score appeared to be positively related to lean body mass(r=.206, p<.01), body fluid(r=.207, p<.01).

• 한방비만학회지
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• 제21권1호
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• pp.22-31
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• 2021

Objectives: We conducted a retrospective chart review to investigate the effects of Korean Medicine (KM) treatment on weight loss in patients with morbid obesity (body mass index [BMI]≥30 kg/m²) and to compare the effects of KM counseling and non-counseling on weight loss. Methods: We performed a retrospective chart review of patients with morbid obesity who received KM treatment for at least 1 month. We evaluated the effects of KM treatment on body weight, BMI, body fat, fat mass, EuroQol-5D, and the Korean version of the obesity-related quality of life scale (KOQOL). We also assessed the liver and kidney functions, and adverse events. We performed a comparative analysis between the counseling and non-counseling groups. Results: A total of 37 patients who underwent 4 weeks of KM treatment involving Wolbi-tang, electroacupuncture, and KM counseling were included in this study. Twenty-one patients were assigned to the counseling group and sixteen patients to the non-counseling group. There was a significant decrease in weight, BMI, fat mass, and KOQOL (P<0.05) with improvements in total cholesterol, low-density lipoprotein, and triglycerides. The counseling group had a greater reduction in body weight, BMI, body fat, and fat mass compared to the non-counseling group, although it was not significant. In the BMI below 35 (n=25), the reduction ratio of body weight, body fat mass, and body fat was higher in the counseling group than in the non-counseling group; additionally, body fat decreased significantly in counseling group (P<0.05). No severe adverse effects were observed. Conclusion: KM treatment could be effective for weight loss, especially in patients with morbid obesity, KM counseling could also be a good tool for weight loss, typically in patients with BMI<35 kg/m².

• 성인간호학회지
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• 제22권6호
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• pp.615-623
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• 2010

Purpose: The purpose of this study was to evaluate the influence of the Koryo Hand Acupuncture Therapy on middle-age women s obesity index. Methods: A total of 38 middle-age women were assigned to either a control or an intervention group. The intervention group received Koryo Hand Acupuncture Therapy three times a week for ten weeks. The two sample t-test was used to compare the body mass index, fat mass, and waist-to-hip ratio between the intervention (n=18) and the control group (n=20). Results: In both groups, body mass index did not change significantly following the intervention. The intervention group lost $1.00{\pm}1.10kg$ of fat mass (p=.00) and the decrease was significant between the intervention and control group (p=.00). Both groups had increase in waist-to-hip ratio, however, the increase was only significant for the control group (p=.00). Conclusion: The application of Koryo Hand Acupuncture Therapy influenced the change of fat mass, but not clinically significant. It may be useful to repeat the study and to examine other factors that may have interfered with the effectiveness of the intervention. The use of Koryo hand acupuncture therapy should be further studied.

• 한방비만학회지
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• 제1권1호
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• pp.21-32
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• 2001

Objectives: The aim of this study was to the effect of very low calorie diet with Chegameuiintang to treat obese patients . Methods: We have evaluated 54 obese patients during very low calorie diet with Chegameuiintang weight-reducing regime by determining the body composition before and 1 month, 2 months after treatment by Bioelectrical impedence analysis . Results: In the change of body composition by the treatment, mean weight reduction was 11.59kg(15.57% of initial weight), mean weight reduction after 1month was 7.68kg( 10.31% of initial weight), mean weight reduction after 2 months was 3.91 kg(5.86% of weight after 1 month). Mean reduction in total fat mass was 8.03kg(2914% of the initial fat mass) which constitutes 69.28%. Mean reduction in lean body mass was 3.56kg(7.59%) Conclusions: This study has demonstrated that the compound therapy of very low calorie diet and Chegameuiintang (Tiganyiyiren-tang) is the good way of weight reduction, which reduces total fat mass and preserves lean body mass.

• Nutrition Research and Practice
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• 제15권4호
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• pp.456-467
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• 2021

BACKGROUND/OBJECTIVES: The prevalence of morbid obesity in Korean women has consistently been increasing, while the overall prevalence rate of obesity in Korean women seems to be stable. In addition to bariatric surgery, intragastric balloons (IGBs), as a nonsurgical therapy, have been reported to be effective in weight loss. However, the beneficial effects of IGB in Korean women with obesity have not been fully investigated. The aim of this study was to evaluate the changes in fat mass in Korean women with obesity who had undergone IGB treatment for 6 mon. SUBJECTS/METHODS: Seventy-four women with obesity (body mass index [BMI] ≥ 25.0 kg/m²) were recruited. Clinical data, including general information, comorbidities with obesity, anthropometric data, and changes in the body fat composition before and after IGB treatment, were obtained from the subjects. RESULTS: Most subjects had one or more comorbidities, such as osteoarthropathy and woman's disease, and had poor eating behaviors, including irregular mealtimes, eating quickly, and frequent overeating. Body composition measurements showed that weight, fat mass, and waist-hip circumference ratio decreased significantly at 6 mon after IGB treatment. In particular, women with morbid obesity (BMI ≥ 30 kg/m²) showed 33% excess weight loss. There was no significant difference in skeletal muscle mass and mineral contents after IGB treatment. CONCLUSIONS: This study suggested that 6 mon of IGB treatment can be a beneficial treatment for obesity without muscle mass and bone mineral loss.

• 한방비만학회지
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• 제5권1호
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• pp.141-146
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• 2005

It is very important that the ratio of Soft Lean Mass and Body Fat Mass in body composition. Generally we make an effort not only weight reduction but body fat mass reduction, and finally percent body fat is reduced. And we make an effort to reduce of partial obesity. I have one case that improvement of imbalance on the upper and lower part of the body by Oriental Medicine. We have the result that the upper part of the body composition is increased and the lower part of the body composition is decreased.

• 생약학회지
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• 제46권4호
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• pp.283-288
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• 2015

In this study, we investigated anti-obesity effect of isoegomaketone (IK) isolated from leaves extract of Perilla frutescens (L.) Britt. cv. We verified differentiation and lipid accumulation by Oil Red O staining in 3T3-L1 cells after IK treatment with differentiation media. IK inhibited mRNA expression of adipocyte specific genes that were related with differentiation of 3T3-L1 cells. We confirmed the effects of IK on body weight and visceral fat mass in obese mice. Mice were randomly divided into three groups; normal diet group (ND), high-fat diet group (HFD) and high-fat diet with IK group (HFD-IK). The obesity mice were induced by feeding the 45% high-fat diet to the C57BL/6J mice during 4 weeks. After HFD-IK was orally administered 10 mg/kg of IK. As a result, the body weight of HFD and HFD-IK was increased 2.4 times and 1.7 times of ND, respectively. Also visceral fat mass of HFD was increased 24 times but in the case of HFD-IK was increased to 13 times in comparison with ND. Taken together, our findings suggest that IK reduced differentiation and adiogenesis in 3T3-L1 cells, decreased the body weight and visceral fat mass in obesity mice. These results suggest that IK may have a potential benefit as anti-obesity material.

• Preventive Nutrition and Food Science
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• 제13권3호
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• pp.146-156
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• 2008

The enhancement of the human body fat reduction of conjugated linoleic acid (CLA) with the supplementation of $\gamma$-oryzanol (OZ) was investigated on overweight Korean women (n=51, BMI> 23). Subjects were divided into 4 groups of control, CLA, glyceride form of CLA (GCLA), and CLA plus OZ (CLA-OZ). The soft-gel capsule (500 mg) was used to deliver control (500 mg olive oil), CLA (500 mg CLA), GCLA (500 mg GCLA) and CLA-OZ (500 mg CLA plus 50 mg OZ). Three capsules were taken twice a day for 12 weeks. The CLA-OZ supplementation reduced 1.35% body fat that was 0.34% enhancement against CLA supplementation. As considered subject variations, CLA-OZ reduced body fat ranged from 7.9% to -2.7%, equivalent to 5.6 kg loss to 0.7 kg gain in body fat mass, against CLA. The CLA-OZ reduced body weight and body mass index (BMI), relative to control, but the reductions by CLA-OZ were not different from those by CLA and GCLA. All biochemical markers analyzed for safty were not significantly different within or between groups and were within the normal range. The CLA-OZ supplementation significantly reduced blood pressure, as compared to the supplementation of CLA, GCLA and control. These results suggest that OZ could be a useful ingredient to mix with CLA for the reduction of human body fat.