• 한국콘텐츠학회논문지
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• 제21권12호
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• pp.585-594
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• 2021

가족결합은 이주민의 행복과 사회통합에 중요한 요인이다. 따라서 유엔은 난민협약상 난민으로 인정되지는 않지만, 출신국으로 귀환할 경우 심각한 위해를 입을 상당한 근거가 있어 국제적 보호가 필요하다고 판단되는 보충적 보호대상자에 대해서도 난민과 같은 수준에서의 가족결합권 보장을 권고하고 있다. 한국은 보충적 보호 대상자와 유사한 인도적 체류자 제도가 있지만, 난민과 달리 가족결합권을 보장받지 못한다. 본 연구는 보충적 보호 대상자의 가족결합권과 관련하여 스웨덴, 아일랜드, 호주, 캐나다 등 해외사례를 살펴봄으로써 한국의 인도적 체류자 가족결합 보장에 대한 대안을 도출하고자 하였다. 분석결과 국가별로 허용기간이나 범위에 있어 차이가 있지만 공통적으로 가족결합을 인정하고 있었다. 또한 가족결합권은 국제규약에서 기본적 인권으로 간주할 뿐만 아니라 인도적 체류자처럼 취약한 상황에 있는 이들에게는 수용국에서의 적응을 위한 심리적 기반이라는 점에서 우리나라도 인도적 체류자의 가족결합권 보장을 구체화할 것을 제안하였다.

• 토지주택연구
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• 제11권1호
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• pp.21-38
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• 2020

This study examined the population movement of the young generation in accordance with the characteristics of housing market focusing on the housing problem of youth issues. Targeting 64 local governments in the seoul metropolitan area, the temporal range was decided as 2015. Setting up the rising population in 19-34 as a dependent variable, supposing that each age group shows different characteristics, it was divided into age groups in 19~34, 19~29, and 25~34. The population movement of the young generation in accordance with the characteristics of housing market was considered through the multiple regression analysis. In the results, the population movement of the young generation was influenced by the change in detached multi-family housing and the rate of housing supply. The increase of detached multi-family housing promoted the population inflow of the young generation while the population movement of the young generation was disturbed by the rising rate of housing supply. Also, when the local characteristics are not controlled, the young generation hesitates to enter the region where relatively high rent should be paid while the new housing supply focusing on apartment is hard to be selected by the young generation for residence because of the size and price. The population movement of the young generation looked quite different in each age group. The population inflow of the young generation in 19~29 was influenced when there were many officetels and non-apartments on top of detached multi-family housing. On the contrary, the population movement of the young generation in 25~34 was significantly influenced by the increase of the whole size of completed apartment area. Even though it was not the research subject of this study, among control variables, the financial independence and daily average number of get-on/off had effects on the movement of the young generation. It means that the housing type preferred by college students and social novices is different from the housing type preferred by the group with experiences in marriage and childbirth within the same young generation. Thus, it would be necessary to divide the purposes of policies for each subject when executing the youth housing policies.

• Animal cells and systems
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• 제13권1호
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• pp.9-15
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• 2009

Eph receptors and their ephrin ligands have been implicated in a variety of cellular processes such as cellular morphogenesis and motility. Our previous studies demonstrated that Odin, one of the Anks family proteins, functions as a scaffolding protein of the EphA8 signaling pathway leading to modulation of cell migration or axonal outgrowth. Here we show that WDR7 is associated with Odin and that it is possibly implicated in the EphA8 signaling pathway. WD40 repeats present in the COOH-terminal region of WDR7 appear to be crucial for its association with Odin, whereas the binding motif of Odin is located in between ankyrin repeats and PTB domain. Co-immunoprecipitation experiments revealed that association of WDR7 with Odin is enhanced by ephrin ligand treatment, possibly through forming large protein complexes including both EphA8 and ephrin-A5. Consistently, immunofluorescence staining experiments suggested that WDR7 constitute a component of the large protein complexes containing Odin, EphA8 and ephrin-A5. Taken together, our results suggest the WDR7-Odin complexes might be involved in the signaling pathway downstream of the EphA8 receptor.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제24권3호
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• pp.124-131
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• 2013

South Korea is changing into a multi-cultural society, due to an increase in international marriage, foreign workers and transcultural immigration. In addition, the number of North Korean defectors entering South Korea has increased and now, there are approximately 25000. Therefore, this review have focused on a research that pertains to adaptation and mental health concerns of their children. Children who have immigrated themselves or whose parents have immigrated, might experience language barriers, difficulties in school adjustment, identity confusion and mental health problems. However, their academic performance and developmental status are known to be variable and be affected by socioeconomic status and their parents' educational level. Studies that evaluated the psychological problems of North Korean adolescent refugees' indicated the need for interests in both emotional and behavioral problems. The risk factors of North Korean adolescent refugees' mental health are suggested to be past traumatic experiences, long duration of defection and short period of adaptation. When mental health professionals provide assessment and treatment, they should consider the pre- and post-migration experiences & cultural background that affect the illness behaviors and attitudes toward mental illnesses. Lastly, the majority of children with multi-cultural background are still under an adolescent period and we should follow up with long-term perspectives.

• 한국식품조리과학회지
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• 제7권1호
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• pp.1-9
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• 1991

The purpose of this study is to investigate the management of Indigenous fermented foods during the period of economic development starting from 1960 until now, and to specify their correlation, while paying special concern to the variables of social change such as the increase of people's income, ceaseless migration of population, change in the family structure, heightening up of the educational level of women and the resulting increase of chances for getting employment, all of which may affect the management of Indigenous fermerted foods in korean families. The result is as follows. Basic seasonings and dishes such as soy bean sauce, red pepper paste, pickled seafoods, and Kimchi, are inclined to be bought as readymade products or provided by relatives in case of many nuclear families rather than made at home, which is a traditional way of home life. However, Kimchi and basic sauces or redpepper paste still show high rate of being made at home. Social variables which affect such tendency are the number of family members, the age and educational level of housewife, and the type of residence.

• 한국인구학
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• 제11권1호
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• pp.185-196
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• 1988

광역도시내 대도시와 신도시는 경제적인 유기체임에도 불구하고 임의적인 행정구역으로 분할되어 있다. 이 결과 대도시는 신도시 주민들을 위하여 막대한 재원을 투자하여 도시기반시설을 건설하여야 하나, 상주인구의 감소로 재원부족이라는 어려움에 빠지게 된다. 본 연구는 1990년 미국 센서스 1% 자료를 이용하여 53개 광역도시내 인구이동을 분석하여 대도시가 도시기반시설에 투자를 하면 할수록 신도시로 대도시 인구가 빠져나가는 "신도시 주민의 대도시 찰취가설"을 입증하였다. 결국 광역도시내에 상이한 지방정부가 존재하는 경우 지방정부서비스 공급은 티부이론이 제시하는 효율성을 달성하지 못하기 때문에 광역도시내 정부 서비스의 공급은 사무엘슨 방식의 통합적 제공이 필요하다. 제공이 필요하다.

• BMB Reports
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• 제57권6호
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• pp.305-310
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• 2024

T-plastin (PLST), a member of the actin-bundling protein family, plays crucial roles in cytoskeletal structure, regulation, and motility. Studies have shown that the plastin family is associated with the malignant characteristics of cancer, such as circulating tumor cells and metastasis, by inducing epithelial-mesenchymal transition (EMT) in various cancer cells. However, the role of PLST in the EMT of human lung cancer cells remains unclear. In this study, we observed that PLST overexpression enhanced cell migratory and invasive abilities, whereas its downregulation resulted in their suppression. Moreover, PLST expression levels were associated with the expression patterns of EMT markers, including E-cadherin, vimentin, and Slug. Furthermore, the phosphorylation levels of focal adhesion kinase (FAK) and AKT serine/threonine kinase (AKT) were dependent on PLST expression levels. These findings indicate that PLST induces the migration and invasion of human lung cancer cells by promoting Slug-mediated EMT via the FAK/AKT signaling pathway.

• BMB Reports
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• 제55권2호
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• pp.87-91
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• 2022

Aurora kinase is a family of serine/threonine kinases intimately associated with mitotic progression and the development of human cancers. Studies have shown that aurora kinases are important for the protein kinase C (PKC)-induced invasion of colon cancer cells. Recent studies have shown that aurora kinase A promotes distant metastasis by inducing epithelial-to-mesenchymal transition (EMT) in colon cancer cells. However, the role of aurora kinase A in colon cancer metastasis remains unclear. In this study, we investigated the effects of aurora kinase A on PKC-induced cell invasion, migration, and EMT in human SW480 colon cancer cells. Treatment with 12-O-tetradecanoylphorbol-13-acetate (TPA) changed the expression levels of EMT markers, increasing α-SMA, vimentin, and MMP-9 expression and decreasing E-cadherin expression, with changes in cell morphology. TPA treatment induced EMT in a PKC-dependent manner. Moreover, the inhibition of aurora kinase A by siRNAs and inhibitors (reversine and VX-680) suppressed TPA-induced cell invasion, migration, and EMT in SW480 human colon cells. Inhibition of aurora kinase A blocked TPA-induced vimentin and MMP-9 expression, and decreased E-cadherin expression. Furthermore, the knockdown of aurora kinase A decreased the transcriptional activity of NF-κB and AP-1 in PKC-stimulated SW480 cells. These findings indicate that aurora kinase A induces migration and invasion by inducing EMT in SW480 colon cancer cells. To the best of our knowledge, this is the first study that showed aurora kinase A is a key molecule in PKC-induced metastasis in colon cancer cells.

• 대한가정학회지
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• 제11권4호
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• pp.414-423
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• 1973

Before the modern education was introduced in Korea men had the opportunity to be educated. Women's education was limited to a small number of girls belonging to ruling class. It was the men who got a job to earn the money for the family. The customary law prohibited women from being employed. They were to stay at home engaged in household affairs. This phenomenon has undergone a change when modern education was adopted which gave women the equal opportunity in education. The modernization of the country required a lot of educated and skilled labour. Since 1945 when Korea was liberated from the Japanese colonial administration the modernization programme has been worked out in every field such as industry, education, culture and politics, etc. The traditional grand family was transformed to nuclear family. The migration took place from country to town. With the adoption of compulsory education in the primary school the schoolgirls are increased in great number. The number of girls has been increased every year in Middle Schools, High schools and Universities. Even if boys still outnumber girls in all education institutions, the rate of increase of girl students are higher than that of boy students. Accordingly women are given more opportunity than ever for the employment vis-a-vis men. The number of employed women has been increasing greatly in recent years inproportion to the acceleration of industrialization. The type of their job is also various and colorful ranging from factory worker to doctor and lawyer. There are some problems to be solved with respect to the improvement of women's education. The improved women's education should be reviewed light of the fact that inequality still exists between men and women in occupation and wages, and that women is required of good education contributable to the better Korean society.

• Biomolecules & Therapeutics
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• 제28권1호
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• pp.110-118
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• 2020

Migration presents a substantial social and public health issue. However, it is unclear whether diabetes is worse among Asian migrants than natives of South Korea over time. This longitudinal study investigated the nationwide population, including 2,680,495 adults aged 20 years and older (987,214 Asian migrants and 1,693,281 natives), who received health check-ups, using the Korean National Health Insurance Service data (2009-2015). Joinpoint regression was used to estimate the annual percentage change of diabetes, and multivariable logistic regression was used to examine differences in incident type 2 diabetes between Asian migrants and natives adjusting for age, sex, economic status, body mass index, smoking status, any alcohol use, and physical activity. The age-adjusted prevalence of diabetes increased among native men (from 8.8% in 2009 to 9.7% in 2015, APC=1.64, p<0.05) compared to Asian migrant men, and the age-adjusted prevalence of diabetes increased among native women (from 6.0% in 2009 to 6.7% in 2015, APC=1.88, p<0.05) compared to Asian migrant women. In the multivariate analyses, Asian migrants were less likely to get type 2 diabetes than natives (odds ratio, 0.82; 95% CI, 0.78 to 0.86) between the first and last health check-ups. However, the odds ratio for developing type 2 diabetes was 1.15 (95% CI, 1.10 to 1.20) among low-income levels compared to high-income levels, regardless of whether they were Asian migrants or natives. The results could help to establish a new strategy for prevention, treatment, and management of diabetes among the Asian population.