• Toxicological Research
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• 제23권1호
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• pp.1-9
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• 2007

Transporters are membrane proteins that mediate the transfer of substrate across the cellular membrane. In this overview, the characteristics and the toxicological relevance were discussed for various types of transporters. For drug transporters, the overview focused on ATP-binding cassette transporters and solute carrier family 21A/22A member transporters. Except for OCTN transporters and OATP transporters, drug transporters tend to have broad substrate specificity, suggesting drug-drug interaction at the level of transport processes (e.g., interaction between methotrexate and non-steroidal anti-inflammatory agents) is likely. For metal transporters, transporters for zinc, copper and multiple metals were discussed in this overview. These metal transporters have comparatively narrow substrate specificity, except for multiple metal transporters, suggesting that inter-substrate interaction at the level of transport is less likely. In contrast, the expressions of the transporters are often regulated by their substrates, suggesting cellular adaptation mechanism exists for these transporters. The drug-drug interactions in drug transporters and the cellular adaptation mechanisms for metal transporters are likely to lead to alterations in pharmacokinetics and cellular metal homeostasis, which may be linked to the development of toxicity. Therefore, the transporter-mediated alterations may have toxicological relevance.

• International Journal of Advanced Culture Technology
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• 제8권3호
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• pp.159-165
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• 2020

The purpose of this study is to consider the home environment and awareness of elementary school students in the first grade of elementary school, and to find ways to support them. Participants were 31 1st graders in elementary schools nationwide. Data collection was conducted from June 6, 2017 to July 7, 2017. The focus group interview was used as a data collection method for this study. Results were analyzed as 'The Changing family environment that first graders think' and 'First graders' awareness of elementary school'. 'The Changing family environment that first graders think' include 'Changes in language used by parents', 'Changes in how parents and families live', and 'What to do after school'. 'First graders' awareness of elementary school' was analyzed as 'Awareness of Elementary school life', 'Awareness of peers', 'Awareness of homeroom teacher', and 'Awareness of learning'. As the conclusion of this study, we suggest that because the children have more free time than attending kindergarten, they need quality programs and support plans to support their first grade primary adjustment. Also, we propose a common problem facing first-year students: the difficulty of adjusting to study and support for how to study in an easier way.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제24권3호
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• pp.124-131
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• 2013

South Korea is changing into a multi-cultural society, due to an increase in international marriage, foreign workers and transcultural immigration. In addition, the number of North Korean defectors entering South Korea has increased and now, there are approximately 25000. Therefore, this review have focused on a research that pertains to adaptation and mental health concerns of their children. Children who have immigrated themselves or whose parents have immigrated, might experience language barriers, difficulties in school adjustment, identity confusion and mental health problems. However, their academic performance and developmental status are known to be variable and be affected by socioeconomic status and their parents' educational level. Studies that evaluated the psychological problems of North Korean adolescent refugees' indicated the need for interests in both emotional and behavioral problems. The risk factors of North Korean adolescent refugees' mental health are suggested to be past traumatic experiences, long duration of defection and short period of adaptation. When mental health professionals provide assessment and treatment, they should consider the pre- and post-migration experiences & cultural background that affect the illness behaviors and attitudes toward mental illnesses. Lastly, the majority of children with multi-cultural background are still under an adolescent period and we should follow up with long-term perspectives.

• 한국식품조리과학회지
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• 제32권1호
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• pp.76-83
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• 2016

The purpose of this study was to analyze meal management behaviors for Korea dietary acculturation among multicultural families in Korea. The study compared differences in meal management behaviors among 90 multicultural families. Results of the study were as follows: cultural adaptation to Korea got higher with increasing age; marriage immigrants with longer marriage duration and with children showed higher cultural adaptation to Korea. Regarding food value of marriage immigrant women, 'eating favorite food' was the highest in the 20s, while 'satisfaction with Korean dietary lifestyle' was high in Chinese and in those with longer residency. Most of them replied 'myself' for the meal manager of their multicultural family. When surveyed on major difficulties in Korean meal management, existence of children showed significant difference for 'cooking', and period of residency and existence of children made significant difference for 'taste'. In conclusion, meal management behavior of multicultural families was influenced by socioeconomic factors. Further research is needed for more quantitative analysis and understanding of the effect of dietary patterns on nutritional status and quality of life in multicultural families.

• 대한가정학회지
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• 제45권6호
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• pp.89-100
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• 2007

The objective of this study was to analyze children's maladjustment behavior as related to sex, temperament, and the mother's maternal attitudes, and to characterize the relative influence of these variables on the maladjustment behavior of 3-5 year old children in early child education centers. The subjects were recruited from Gwangju City, and included 217 mothers, and the teachers of their children. Statistical analyses were conducted using SPSSWIN(12.0) for Cronbach's alpha, t-test, one-way ANOVA, Pearson's correlation, and multiple regression analysis. The major findings are as follows; 1. Statistically significant differences existed in the maternal overprotective attitude group with regard to anxiety and withdrawal behaviors. 2. Boys evidenced more aggression, inattention, impulse, and anxiety behaviors than did girls. 3. The activity and adaptation factors of temperaments were significantly different. Increasing activity was associated with increasing aggressive behavior. Increasing adaptation was associated with higher levels of distraction. 4. In terms of maladjustment behaviors in the aggregate, the sex of the children appeared to be the most salient influencing factor, and the activity factor of children's temperament also exerted a significant influence, explaining 13% of maladjustment behavior.

• 여성건강간호학회지
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• 제18권4호
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• pp.257-267
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• 2012

Purpose: This study was conducted to identify the caring experience of the mothers of childhood burn patients. Methods: Data were collected from 28 mothers of childhood burn patients, through semi-structured in-depth interviews. Data were categorized and coded by using content analysis. Results: 27 categories and 102 statements were drawn from 4 domains. The analyzed domains were psychological sufferings, confronted harsh reality, coping method, and future concerns. Psychological sufferings were categorized heartache, sense of guilt, confusion, regret, depression, sorriness, getting hurt, frustration and upset feeling. Confronted harsh nature were categorized economic difficulty, physical burn-out, lack of caring other children and family troubles. Coping method were categorized positive thinking, having hope, ventilating feelings, accepting the situations, demanding help from family members, changing patterns of the burned child rearing, collecting information for burn treatment, refusing accept the condition of burned child, avoiding personal and social relationship, and reliance on religion. Concerns were categorized concerns of growth and adaptation of the burned child, anxiety for scar, concerns of adapting school life and vague future concerns. Conclusion: The nursing interventions for early assessing psychological problems and providing social supports for caring both burn patients and other siblings should be provided to the mothers of childhood burn patients.

• 가정과삶의질연구
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• 제19권6호
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• pp.35-50
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• 2001

The purpose of this study was to examine the effects of family violence, peer\`s deviant behavior, school environment, and accessibility of violence through a mass media, mediated by school violence, on adolescents 'psychological & behavioral maladjustment. The present study was the primary research of developing program for adolescents'psychological & behavioral adaptation to school violence. On the basis of previous literature, the theoretical model was specified, estimated, and evaluated for adequacy of statistical fat. Subjects of this study consisted of 974 adolescents drawn from middle and high schools in Cheong-ju. The model was supported by the data. Family violence, peer's deviant behavior, school environment, and accessibility of violence through a mass media explained directly the variance of school violence and adolescents'psychological & behavioral maladjustment. The results shows that adolescents'psychological & behavioral maladjustment can be viewed as products of the interaction with environmental factors and school violence. Accessibility of violence through a mass media was strongly related to school violence. Also, school violence was the strongest risk factor in relation to adolescents'behavioral maladjustment while school environment to adolescents'psychological maladjustment. Therefore, prevention program for school violence should consider the psychological & behavioral components within the environmental context.

• 노인간호학회지
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• 제20권3호
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• pp.193-203
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• 2018

Purpose: This study was done to develop a predictive model for quality of life of elderly residents in long-term care facilities (LTCF). The study was based on Brofenbrenner's ecological system theory and a literature review. Methods: Data were collected using a convenience sample of 205 elderly residents in 2 nursing homes located in D city and 1 nursing home located in K province. The exogenous variables were individual factors, family support, and facility environmental factors. The endogenous variables were self-esteem, accommodation adaptation and quality of life of elderly residents in LTCF. Collected data were analyzed through structural equation modeling using AMOS 20.0. Results: Eleven of the twelve hypotheses were supported, but the hypothesis that facility environment factors effect self-esteem was not supported. Quality of life of elderly residents in LTCF was explained first by facility environmental factors, followed by self-esteem, individual factors, accommodation adaptation, and family support with an explanatory power of 83.0%. Conclusion: To improve the quality of life of elderly residents in LTCF, the service and environment preparation provided by facilities is important, and it is necessary to provide emotional counseling to improve the self-esteem of these elders.

• 한국가족관계학회지
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• 제21권2호
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• pp.97-127
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• 2016

Objective: This study explored benefits of a relationship-focused intervention to enhance marriage communication designed for multicultural married couples and changes that occurred in the way the program's participants communicated with one another. Method: The intervention program was implemented on six married multicultural couples (and six other couples as a control group), and their communication, conflict resolution, and adaptation before and after the intervention were examined. In addition, the researchers kept observation journals to understand the changes in the manner in which the married multicultural couples communicated with their spouse and examine their perception about participating in the program; further, we conducted post-program interviews with the participants after the completion of the program. Results: The results of this study are as follows: (1) the experiment group made more progress in improving couple communication, resolving marriage conflicts, and adapting as a married couple than the control group in a statistically significant manner in both preand post-program tests, and (2) the study confirmed through qualitative analysis that the program made positive contributions to improving the couples' abilities to have conversations and resolve conflicts, as well as their intimacy. Conclusion: Based on these results, implications for further research and practices were discussed.

• Human Ecology Research
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• 제61권4호
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• pp.635-645
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• 2023

This study examined the trends of domestic academic research on children of divorced families by classifying them by period, method, target, and subject. From 2000 to 2022, 105 papers published in 58 journals were surveyed. In terms of research methods, quantitative research was conducted using questionnaires and panel data. The subjects of the reviewed studies were mainly elementary school children, and there were many studies on both divorced single mother and child families as well as divorced single father and child families. By analyzing the core subjects of the study, papers related to children's personal adaptation accounted for the largest proportion, followed by problematic behaviors, psychological difficulties, such as depression and stress, and relationships. In conclusion, due to the high divorce rate in Korea there is a need to focus academic attention on the children of divorced families. To this end, it is necessary to study the adaptation and protection factors of the children of divorced families. More qualitative research should be conducted on children of divorced families of various ages, not just elementary school students.