• Asian Pacific Journal of Cancer Prevention
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• 제15권22호
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• pp.9905-9908
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• 2014

Background: Helicobacter pylori (H. pylori) is the most common chronic infectious agent in the stomach. Most importantly, it may lead to atrophy, metaplasia and cancer. The aim of this study was to investigate the incidence of H. pylori infection and to detect early mucosal changes that may lead to malignant degeneration in children. Materials and Methods: Children who underwent upper gastrointestinal endoscopy were included. Familial history of gastric cancer was noted. Endoscopic examinations were performed by a single pediatric gastroenterologist. A minimum of three biopsy samples were collected during endoscopy. The patients were accepted as H. pylori infected if results of biopsies and rapid urease test were both positive. Biopsies were evaluated for the presence and degree of chronic inflammation, the activity and severity of gastritis, glandular atrophy and intestinal metaplasia. Results: A total of 750 children (388 boys, 362 girls) were evaluated in our study, with a mean age of 10.1 years. A total of 390 patients (52%) were found to be infected with H. pylori. Among the H. pylori infected patients, 289 (74%) were diagnosed to have chronic superficial gastritis, 24 (6.2%) had gastric atrophy. Most strikingly, intestinal metaplasia was observed in 11 children, all were in the H. pylori positive group. There was no difference in the mean of age, gender and socioeconomic class between H. pylori infected and non-infected groups. The frequency of gastric cancer in family members (4 in number) was higher in patients with H. pylori infection. No gastric cancer case was reported from the parents of non-infected children. The worst biopsy parameters (atropy and metaplasia) were improved after H. pylori eradication on control endoscopy. Conclusions: The current study shows a higher prevalence of familial history of gastric cancer in H. pylori infected children. Intestinal metaplasia was also higher in the infected children. Eradication of H. pylori infection for this risk group may prevent subsequent development of gastric cancer.

• Journal of Preventive Medicine and Public Health
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• 제19권2호
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• pp.281-292
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• 1986

Infection by hepatitis B virus is one of the major health problems of this nation. HBsAg positive rates of general population and school children were known to be as about 8 percent and 3.9 to 5.9 percent respectively. To study the incidence rate of hepatitis B infection in school children of rural area, author had examined 475 school children of relatively isolated agricultural area for baseline prevalence of hepatitis B virus serologic markers and followed up 415 school children during 10 months to determined the frequency of serologic conversion. The major results are summarized as followings: 1) Among the 278 susceptible children who were followed up, 26 had seroconversion for HBsAg or Anti-HBs. Therefore, the cumulative incidence rate during 10 months is estimated 9.4%. 2) The incidence rate of hepatitis B infection tends to increase with age (6-9yrs: 3.2%, 10-14yrs: 9.5%, 15-17yrs: 18.9%), and the incidence rate in male (13.0%) was higher than in female (5.7%). 3) The incidence rates of hepatitis B virus infection were not different statistically among three economic classes (The rates of lower, middle and higher class were 11.8%, 7.1% and 10.5%.). 4) The incidence rates of hepatitis B virus infection were not different statistically between visitors and non-visitors of clinic or hospital, dental clinic, persons received IV and not received IV, and persons with familial history and without familial history of liver diseases. Therefore all of these factors were not identified as risk factor of hepatitis B virus infection. And the transmissibility within the class of school was not recognized, too. 5) Among the 25 children who were HBsAg positive when enrolled, 15 (60%) were still HBsAg positive, who were identified as chronic carrier 15 of 415 school children were chronic carriers, then chronic carrier rate was estimated 3.6%, and there was no difference between sexes. 6) Of 38 children who had been Anti-HBs positive when enrolled, 5 (13.2%) lost Anti-HBs. Therefore, the loss rate of Anti-HBs per year is estimated to be 15.8%.

• Imaging Science in Dentistry
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• 제42권1호
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• pp.41-45
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• 2012

Hyperdontia or supernumerary teeth without associated syndrome is a rare phenomenon, as supernumerary teeth are usually associated with cleft lip and palate or other syndromes such as Gardner's syndrome, cleidocranial dysplasia, and so on. Five patients with supernumerary teeth visited our department. They had no familial history or other pathology, certain treatment protocols was modified due to the presence of supernumerary teeth. Non-syndromic supernumerary teeth, if asymptomatic, need to have periodical radiographic observation. If they showed no variation as they impacted in the jaw, careful examination is necessary because they may develop into pathological status such as dentigerous cysts. The importance of a precise clinical history and radiographic examination for patients with multiple supernumerary teeth should be emphasized.

• 미국학
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• 제44권2호
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• pp.131-158
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• 2021

This paper examines how nation-specific history of Asian war brides affects different representations of war brides in Velina Hasu Houston's Tea (1984) and Julia Cho's The Architecture of Loss (2003). While war brides had long been excluded from American history, Japanese war brides were brought to public attention in the 1980s. Korean war brides, on the other hand, were kept out of sight until the 2000s. Focusing on how this time gap is related to ethnic difference, this paper analyzes dramaturgical differences between the two plays such as the presence/absence of war bride on stage or ethnic solidarity/familial reconciliation as the main device of war bride memorialization. Such differences, the paper suggests, stem from ethnic/historical differences between Korean and Japanese war brides. Through historical interpretations of the plays, this paper argues that America's military relationships with Korea and Japan were reproduced within the Asian-American families of each drama in ways that raise questions about pan-Asian identity.

• 대한세포병리학회지
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• 제7권2호
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• pp.213-217
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• 1996

Medullary carcinoma of the thyroid gland is a malignant neuroendocrine tumor arising from calcitonin producing-parafollicular cells. The tumor is clinically divided into sporadic and familial form, constituting about 80% and 20%, respectively. Recently, we experienced a case of unilateral and solitary sporadic medullary carcinoma of the left thyroid gland. The patient was a 9 year-old female, who presented with a palpable mass on the anterior lateral neck of 8 months duration without any familial and personal history of neuroendocrine disease. The cytopathologic findings showed spindle cells and plasmacytoid cells in the background of colloid-like materal. The nuclei were eccentrically located, mildly hyperchromatic and pleomorphic, showing speckled chromatin pattern without nuclear inclusion or prominent nucleoli. The cytoplasm was abundant and had a pale granular cyanophilic appearance. No amyloid materal could be identified.

• Journal of Korean Neurosurgical Society
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• 제57권6호
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• pp.422-427
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• 2015

Moyamoya disease (MMD) is a chronic, progressive, cerebrovascular occlusive disorder that displays various clinical features and results in cerebral infarct or hemorrhagic stroke. Specific genes associated with the disease have not yet been identified, making identification of at-risk patients difficult before clinical manifestation. Familial MMD is not uncommon, with as many as 15% of MMD patients having a family history of the disease, suggesting a genetic etiology. Studies of single nucleotide polymorphisms (SNPs) in MMD have mostly focused on mechanical stress on vessels, endothelium, and the relationship to atherosclerosis. In this review, we discuss SNPs studies targeting the genetic etiology of MMD. Genetic analyses in familial MMD and genome-wide association studies represent promising strategies for elucidating the pathophysiology of this condition. This review also discusses future research directions, not only to offer new insights into the origin of MMD, but also to enhance our understanding of the genetic aspects of MMD. There have been several SNP studies of MMD. Current SNP studies suggest a genetic contribution to MMD, but further reliable and replicable data are needed. A large cohort or family-based design would be important. Modern SNP studies of MMD depend on novel genetic, experimental, and database methods that will hopefully hasten the arrival of a consensus conclusion.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제13권1호
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• pp.70-74
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• 2010

저자들은 닭 간을 생식한 가족에서 복통, 기침, 미열두통 등 동일한 임상증상과 심한 호산구 증가증을 보여면역혈청학적 검사를 통해 진단한 개회충에 의한 내장유충 이행증 1예를 경험하였기에 보고하는 바이다.

• Journal of Periodontal and Implant Science
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• 제23권1호
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• pp.193-200
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• 1993

The purpose of this study is to investigate the relationship between occurrence and inducing factors of herpes labialis developed after periodontal therapy and to suggest prediction model of this lesion. A total of 100 patients were studied. A standard schedule was used for interviews of patients. It included demographic information, patient and familial history of recurrent aphthous ulcer and recurrent herpes labialis, history of systemic disease, religion, and emotional state. In case of female patients, the association of dysmenorrhea and onset of recurrent herpes labialis was also observed. After periodontal therapy, some details about therapy, such as the kind of therapy, location, spending time were recorded. At next appointment, the appearance and location of herpes labialis were examined. The frequency of herpes labialis after periodontal therapy was 8% and the location was predominantly mouth angle. The significant relationship was found between the onset of herpes labialis and the history of recurrent herpes labialis, surgical therapy rather than non-surgical therapy, and spending time. The prediction model of herpes labialis was not apparently established with the results of this study. In conclusion it is suggested that we should minimize traumatic manipulation and treatment time to prevent the onset of herpes labialis after periodontal therapy.

• 건축역사연구
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• 제25권2호
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• pp.31-44
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• 2016

Imcheong-gak[臨淸閣] was a familial residence constructed in the early half of the Joseon dynasty period. It was partially destroyed by a fire during the 1590s war[壬辰倭亂] with the Japanese, and another fire that was caused between 1631 and 1634. The inner chamber[An-chae] and the Sarang section[Sarang-chae] today is the result of a partial reconstruction that took place back in 1626 and again around 1634. The residence also went through some changes because the new Ondol[溫突] heating system had to be applied to the structure. Based upon sections that remain in their original forms, we can presume that the Imcheong-gak residence originally had an inner chamber which was composed of the following elements: A main structure which was built upon a foundation featuring a Matbae[맞배] roof, two "Ik'rang[翼廊, flank]" sections on the East and West sides of the inner chamber, and a "Haeng'rang[行廊, passage]" structure on the opposite side of the main structure. Unlike the main structure, other portions of the inner chamber were all built directly upon the ground, and showed multiple stories, with Matbae roofs of their own. We can also assume that the Sarang section in the south would have been a pre-Ondol[溫突] bedroom, with a Board platform[板房] and a Gomi-ceiling[Gomi-banza] fashion.

• Asian Pacific Journal of Cancer Prevention
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• 제16권5호
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• pp.1719-1724
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• 2015

Background: Breast and cervical cancers are the most common types of cancer in women worldwide. Previous studies in Asia have shown that related knowledge and awareness is low among female university students. The goal of this study was to assess breast and cervical cancer knowledge, practices, and awareness among female university students in Samsun,Turkey. Materials and Methods: This research was a cross-sectional survey of female university students using a self-administered. questionnaire to investigate participant awareness and knowledge of breast and cervical cancer. A total of 301 female university students participated. Descriptive statistics and chi square tests were used for data analysis. Results: The mean age of the participants in this study was $22.0{\pm}5.91$ years. Regarding family history, 89.7 % of the students had no known familial history of breast cancer. Students (65.4%) had knowledge about breast self examination and 52.2 % of them had performed breast self examinationm while 55.1% of them had knowledge about prevention of cervical cancer. Conclusions: Although the results are preliminary, the study points to an insufficient knowledge of university students in Samsun about breast and cervical cancer.